Therapeutic efficacy and molecular mechanisms of snake (Walterinnesia aegyptia) venom-loaded silica nanoparticles in the treatment of breast cancer- and prostate cancer-bearing experimental mouse models

Free Radical Biology and Medicine

Volumn 65, Issue , 2013, Pages 175-189

  Badr, Gamal ^a,b,c   Al Sadoon, Mohamed K ^b,c   Rabah, Danny M ^a,d  

^a KING SAUD UNIVERSITY   (Saudi Arabia)

^b Assiut University   (Egypt)

^c KING SAUD UNIVERSITY   (Saudi Arabia)

^d KING SAUD UNIVERSITY   (Saudi Arabia)

Author keywords

Apoptosis; Bcl 2 family members; Cell signaling; Chemokines; Nanoparticles; Proliferation; Snake venom

Indexed keywords

ANTINEOPLASTIC AGENT; CHEMOKINE RECEPTOR CXCR4; CXCL16 CHEMOKINE; CXCL9 CHEMOKINE; EPIDERMAL GROWTH FACTOR; GAMMA INTERFERON INDUCIBLE PROTEIN 10; NANOCARRIER; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; SILICON NANOPARTICLE; SNAKE VENOM; SOMATOMEDIN C; UNCLASSIFIED DRUG; NANOCONJUGATE; SILICON DIOXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL; CANCER THERAPY; CELL PROLIFERATION; CONTROLLED STUDY; DRUG EFFICACY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN PHOSPHORYLATION; SNAKE; TUMOR XENOGRAFT; WALTERINNESIA AEGYPTIA; ANIMAL; DISEASE MODEL; DRUG DELIVERY SYSTEM; DRUG EFFECTS; DRUG SCREENING; ELAPIDAE; FEMALE; MALE; MAMMARY NEOPLASMS, EXPERIMENTAL; PATHOLOGY; PROCEDURES; PROSTATIC NEOPLASMS; TUMOR CELL LINE; WESTERN BLOTTING;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL PROLIFERATION; DISEASE MODELS, ANIMAL; DRUG DELIVERY SYSTEMS; ELAPID VENOMS; ELAPIDAE; FEMALE; MALE; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; NANOCONJUGATES; PROSTATIC NEOPLASMS; SILICON DIOXIDE; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84884584401     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2013.06.018     Document Type: Article

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