Downregulation of wild-type p53 protein by HER-2/neu mediated PI3K pathway activation in human breast cancer cells: Its effect on cell proliferation and implication for therapy

Cell Research

Volumn 14, Issue 6, 2004, Pages 497-506

  Zheng, Li ^a   Ren, Jia Qiang ^a   Li, Hua ^a   Kong, Zhao Lu ^a   Zhu, Hong Guang ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Breast; Cancer; HER 2 neu; MDM2; p53; PI3K

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; 2-(4-MORPHOLINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE; CHROMONE DERIVATIVE; MORPHOLINE DERIVATIVE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN P53;

ARTICLE; BREAST TUMOR; CELL PROLIFERATION; DOWN REGULATION; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; FEMALE; GENETICS; HUMAN; METABOLISM; PHYSIOLOGY; PROTO ONCOGENE; SIGNAL TRANSDUCTION; TIME; TUMOR CELL LINE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; CHROMONES; DOWN-REGULATION; FEMALE; GENES, ERBB-2; HUMANS; MORPHOLINES; SIGNAL TRANSDUCTION; TIME FACTORS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 21644462450     PISSN: 10010602     EISSN: 17487838     Source Type: Journal    
DOI: 10.1038/sj.cr.7290253     Document Type: Article

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