메뉴 건너뛰기




Volumn 2012, Issue , 2012, Pages

The role of Bcl-2 family proteins in therapy responses of malignant astrocytic gliomas: Bcl2L12 and beyond

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; CASPASE; PROTEIN BCL 2; PROTEIN BCL 2 LIKE 12; PROTEIN BCL XL; PROTEIN MCL 1; PROTEIN P53; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; DACARBAZINE; DRUG DERIVATIVE; TEMOZOLOMIDE;

EID: 84858142877     PISSN: None     EISSN: 1537744X     Source Type: Journal    
DOI: 10.1100/2012/838916     Document Type: Review
Times cited : (47)

References (62)
  • 4
    • 4644251550 scopus 로고    scopus 로고
    • Mutation of P53 in head and neck squamous cell carcinoma correlates with BCL-2 expression and increased susceptibility to cisplatin-induced apoptosis
    • DOI 10.1002/hed.20029
    • Andrews G. A., Xi S., Pomerantz R. G., Lin C. J., Gooding W. E., Wentzel A. L., Wu L., Sidransky D., Grandis J. R., Mutation of P53 in head and neck squamous cell carcinoma correlates with BCL-2 expression and increased susceptibility to cisplatin-induced apoptosis Head and Neck 2004 26 10 870 877 (Pubitemid 39299306)
    • (2004) Head and Neck , vol.26 , Issue.10 , pp. 870-877
    • Andrews, G.A.1    Xi, S.2    Pomerantz, R.G.3    Lin, C.J.4    Gooding, W.E.5    Wentzel, A.L.6    Wu, L.7    Sidransky, D.8    Grandis, J.R.9
  • 5
    • 0028081924 scopus 로고
    • Expression of bcl-2 in small cell lung carcinoma cells
    • Ikegaki N., Katsumata M., Minna J., Tsujimoto Y., Expression of bcl-2 in small cell lung carcinoma cells Cancer Research 1994 54 1 6 8 (Pubitemid 24042076)
    • (1994) Cancer Research , vol.54 , Issue.1 , pp. 6-8
    • Ikegaki, N.1    Katsumata, M.2    Minna, J.3    Tsujimoto, Y.4
  • 6
    • 0030740592 scopus 로고    scopus 로고
    • BCL2 overexpression associated with chromosomal amplification in diffuse large B-cell lymphoma
    • Monni O., Joensuu H., Franssila K., Klefstrom J., Alitalo K., Knuutila S., BCL2 overexpression associated with chromosomal amplification in diffuse large B-cell lymphoma Blood 1997 90 3 1168 1174 (Pubitemid 27314153)
    • (1997) Blood , vol.90 , Issue.3 , pp. 1168-1174
    • Monni, O.1    Joensuu, H.2    Franssila, K.3    Klefstrom, J.4    Alitalo, K.5    Knuutila, S.6
  • 7
    • 0037276437 scopus 로고    scopus 로고
    • The CD95(APO-1/Fas) DISC and beyond
    • DOI 10.1038/sj.cdd.4401186
    • Peter M. E., Krammer P. H., The CD95(APO-1/Fas) DISC and beyond Cell Death and Differentiation 2003 10 1 26 35 (Pubitemid 36511830)
    • (2003) Cell Death and Differentiation , vol.10 , Issue.1 , pp. 26-35
    • Peter, M.E.1    Krammer, P.H.2
  • 8
    • 37549048249 scopus 로고    scopus 로고
    • The BCL-2 protein family: Opposing activities that mediate cell death
    • Youle R. J., Strasser A., The BCL-2 protein family: opposing activities that mediate cell death Nature Reviews Molecular Cell Biology 2008 9 1 47 59
    • (2008) Nature Reviews Molecular Cell Biology , vol.9 , Issue.1 , pp. 47-59
    • Youle, R.J.1    Strasser, A.2
  • 9
    • 78149449341 scopus 로고    scopus 로고
    • BH3-triggered structural reorganization drives the activation of proapoptotic BAX
    • Gavathiotis E., Reyna D. E., Davis M. L., Bird G. H., Walensky L. D., BH3-triggered structural reorganization drives the activation of proapoptotic BAX Molecular Cell 2010 40 3 481 492
    • (2010) Molecular Cell , vol.40 , Issue.3 , pp. 481-492
    • Gavathiotis, E.1    Reyna, D.E.2    Davis, M.L.3    Bird, G.H.4    Walensky, L.D.5
  • 10
    • 0030715323 scopus 로고    scopus 로고
    • Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
    • Li P., Nijhawan D., Budihardjo I., Srinivasula S. M., Ahmad M., Alnemri E. S., Wang X., Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade Cell 1997 91 4 479 489 (Pubitemid 27508237)
    • (1997) Cell , vol.91 , Issue.4 , pp. 479-489
    • Li, P.1    Nijhawan, D.2    Budihardjo, I.3    Srinivasula, S.M.4    Ahmad, M.5    Alnemri, E.S.6    Wang, X.7
  • 11
    • 27544471076 scopus 로고    scopus 로고
    • The mitochondrial death squad: Hardened killers or innocent bystanders?
    • DOI 10.1016/j.ceb.2005.09.001, PII S0955067405001389
    • Ekert P. G., Vaux D. L., The mitochondrial death squad: hardened killers or innocent bystanders? Current Opinion in Cell Biology 2005 17 6 626 630 (Pubitemid 41540412)
    • (2005) Current Opinion in Cell Biology , vol.17 , Issue.6 , pp. 626-630
    • Ekert, P.G.1    Vaux, D.L.2
  • 16
    • 0031059570 scopus 로고    scopus 로고
    • Immunohistochemical analysis of Bcl-2, Bcl-X, Mcl-1, and Bax in tumors of central and peripheral nervous system origin
    • Krajewski S., Krajewska M., Ehrmann J., Sikorska M., Lach B., Chatten J., Reed J. C., Immunohistochemical analysis of Bcl-2, Bcl-X, Mcl-1, and Bax in tumors of central and peripheral nervous system origin American Journal of Pathology 1997 150 3 805 814 (Pubitemid 27106152)
    • (1997) American Journal of Pathology , vol.150 , Issue.3 , pp. 805-814
    • Krajewski, S.1    Krajewska, M.2    Ehrmann, J.3    Sikorska, M.4    Lach, B.5    Chatten, J.6    Reed, J.C.7
  • 17
    • 0030794452 scopus 로고    scopus 로고
    • The anti-apoptosis function of: Bcl-2 can be genetically separated from its inhibitory effect on cell cycle entry
    • DOI 10.1093/emboj/16.15.4628
    • Huang D. C. S., O'Reilly L. A., Strasser A., Cory S., The anti-apoptosis function of: Bcl-2 can be genetically separated from its inhibitory effect on cell cycle entry EMBO Journal 1997 16 15 4628 4638 (Pubitemid 27326600)
    • (1997) EMBO Journal , vol.16 , Issue.15 , pp. 4628-4638
    • Huang, D.C.S.1    O'Reilly, L.A.2    Strasser, A.3    Cory, S.4
  • 18
    • 1342306819 scopus 로고    scopus 로고
    • Conversion of Bcl-2 from Protector to Killer by Interaction with Nuclear Orphan Receptor Nur77/TR3
    • DOI 10.1016/S0092-8674(04)00162-X
    • Lin B., Kolluri S. K., Lin F., Liu W., Han Y. H., Cao X., Dawson M. I., Reed J. C., Zhang X. K., Conversion of Bcl-2 from protector to killer by interaction with nuclear orphan receptor Nur77/TR3 Cell 2004 116 4 527 540 (Pubitemid 38264430)
    • (2004) Cell , vol.116 , Issue.4 , pp. 527-540
    • Lin, B.1    Kolluri, S.K.2    Lin, F.3    Liu, W.4    Han, Y.-H.5    Cao, X.6    Dawson, M.I.7    Reed, J.C.8    Zhang, X.-K.9
  • 22
    • 23944445368 scopus 로고    scopus 로고
    • A role for proapoptotic BID in the DNA-damage response
    • DOI 10.1016/j.cell.2005.06.022, PII S0092867405006410
    • Zinkel S. S., Hurov K. E., Ong C., Abtahi F. M., Gross A., Korsmeyer S. J., A role for proapoptotic BID in the DNA-damage response Cell 2005 122 4 579 591 (Pubitemid 41191156)
    • (2005) Cell , vol.122 , Issue.4 , pp. 579-591
    • Zinkel, S.S.1    Hurov, K.E.2    Ong, C.3    Abtahi, F.M.4    Gross, A.5    Korsmeyer, S.J.6
  • 23
    • 0032510679 scopus 로고    scopus 로고
    • Drug resistance of human glioblastoma cells conferred by a tumor-specific mutant epidermal growth factor receptor through modulation of Bcl-XL and caspase-3-like proteases
    • Nagane M., Levitzki A., Gazit A., Cavenee W. K., Huang H. J. S., Drug resistance of human glioblastoma cells conferred by a tumor-specific mutant epidermal growth factor receptor through modulation of Bcl-XL and caspase-3-like proteases Proceedings of the National Academy of Sciences of the United States of America 1998 95 10 5724 5729
    • (1998) Proceedings of the National Academy of Sciences of the United States of America , vol.95 , Issue.10 , pp. 5724-5729
    • Nagane, M.1    Levitzki, A.2    Gazit, A.3    Cavenee, W.K.4    Huang, H.J.S.5
  • 24
    • 77953017646 scopus 로고    scopus 로고
    • EGFR and EGFRvIII interact with PUMA to inhibit mitochondrial translocalization of PUMA and PUMA-mediated apoptosis independent of EGFR kinase activity
    • Zhu H., Cao X., Ali-Osman F., Keir S., Lo H. W., EGFR and EGFRvIII interact with PUMA to inhibit mitochondrial translocalization of PUMA and PUMA-mediated apoptosis independent of EGFR kinase activity Cancer Letters 2010 294 1 101 110
    • (2010) Cancer Letters , vol.294 , Issue.1 , pp. 101-110
    • Zhu, H.1    Cao, X.2    Ali-Osman, F.3    Keir, S.4    Lo, H.W.5
  • 25
    • 75749138443 scopus 로고    scopus 로고
    • Notch3 cooperates with the EGFR pathway to modulate apoptosis through the induction of bim
    • Konishi J., Yi F., Chen X., Vo H., Carbone D. P., Dang T. P., Notch3 cooperates with the EGFR pathway to modulate apoptosis through the induction of bim Oncogene 2010 29 4 589 596
    • (2010) Oncogene , vol.29 , Issue.4 , pp. 589-596
    • Konishi, J.1    Yi, F.2    Chen, X.3    Vo, H.4    Carbone, D.P.5    Dang, T.P.6
  • 26
    • 85027926988 scopus 로고    scopus 로고
    • BIM induction of apoptosis triggered by EGFR-sensitive and resistance cell lines of non-small-cell lung cancer
    • Li Z., Zhou S., Zhang L., Su C., Hang J., Zhao Y., Su B., Zhou C., BIM induction of apoptosis triggered by EGFR-sensitive and resistance cell lines of non-small-cell lung cancer Medical Oncology 2011 28 572 577
    • (2011) Medical Oncology , vol.28 , pp. 572-577
    • Li, Z.1    Zhou, S.2    Zhang, L.3    Su, C.4    Hang, J.5    Zhao, Y.6    Su, B.7    Zhou, C.8
  • 27
    • 37549001026 scopus 로고    scopus 로고
    • Proapoptotic BH3-only BCL-2 family protein BIM connects death signaling from epidermal growth factor receptor inhibition to the mitochondrion
    • Deng J., Shimamura T., Perera S., Carlson N. E., Cai D., Shapiro G. I., Wong K. K., Letai A., Proapoptotic BH3-only BCL-2 family protein BIM connects death signaling from epidermal growth factor receptor inhibition to the mitochondrion Cancer Research 2007 67 24 11867 11875
    • (2007) Cancer Research , vol.67 , Issue.24 , pp. 11867-11875
    • Deng, J.1    Shimamura, T.2    Perera, S.3    Carlson, N.E.4    Cai, D.5    Shapiro, G.I.6    Wong, K.K.7    Letai, A.8
  • 28
    • 35648953299 scopus 로고    scopus 로고
    • Gefitinib-induced killing of NSCLC cell lines expressing mutant EGFR requires BIM and can be enhanced by BH3 mimetics
    • DOI 10.1371/journal.pmed.0040316
    • Cragg M. S., Kuroda J., Puthalakath H., Huang D. C. S., Strasser A., Gefitinib-induced killing of NSCLC cell lines expressing mutant EGFR requires BIM and can be enhanced by BH3 mimetics PLoS Medicine 2007 4 10 1681 1690 (Pubitemid 350035457)
    • (2007) PLoS Medicine , vol.4 , Issue.10 , pp. 1681-1690
    • Cragg, M.S.1    Kuroda, J.2    Puthalakath, H.3    Huang, D.C.S.4    Strasser, A.5
  • 29
    • 35648949422 scopus 로고    scopus 로고
    • BIM mediates EGFR tyrosine kinase inhibitor-induced apoptosis in lung cancers with oncogenic EGFR mutations
    • DOI 10.1371/journal.pmed.0040315
    • Costa D. B., Halmos B., Kumar A., Schumer S. T., Huberman M. S., Boggon T. J., Tenen D. G., Kobayashi S., BIM mediates EGFR tyrosine kinase inhibitor-induced apoptosis in lung cancers with oncogenic EGFR mutations PLoS Medicine 2007 4 10 1669 1680 (Pubitemid 350035456)
    • (2007) PLoS Medicine , vol.4 , Issue.10 , pp. 1669-1680
    • Costa, D.B.1    Halmos, B.2    Kumar, A.3    Schumer, S.T.4    Huberman, M.S.5    Boggon, T.J.6    Tenen, D.G.7    Kobayashi, S.8
  • 30
    • 33646774358 scopus 로고    scopus 로고
    • EGFR-dependent downregulation of Bim in epithelial cells requires MAPK and PKC-δ activities
    • Quadros M. R., Connelly S., Kari C., Abrams M. T., Wickstrom E., Rodeck U., EGFR-dependent downregulation of Bim in epithelial cells requires MAPK and PKC- activities Cancer Biology and Therapy 2006 5 5 498 504 (Pubitemid 43765284)
    • (2006) Cancer Biology and Therapy , vol.5 , Issue.5 , pp. 498-504
    • Quadros, M.R.1    Connelly, S.2    Kari, C.3    Abrams, M.T.4    Wickstrom, E.5    Rodeck, U.6
  • 32
    • 0035280247 scopus 로고    scopus 로고
    • Molecular cloning, physical mapping, and expression analysis of a novel gene, BCL2L12, encoding a proline-rich protein with a highly conserved BH2 domain of the Bcl-2 family
    • DOI 10.1006/geno.2000.6455
    • Scorilas A., Kyriakopoulou L., Yousef G. M., Ashworth L. K., Kwamie A., Diamandis E. P., Molecular cloning, physical mapping, and expression analysis of a novel gene, BCL2L12, encoding a proline-rich protein with a highly conserved BH2 domain of the Bcl-2 family Genomics 2001 72 2 217 221 (Pubitemid 32242963)
    • (2001) Genomics , vol.72 , Issue.2 , pp. 217-221
    • Scorilas, A.1    Kyriakopoulou, L.2    Yousef, G.M.3    Ashworth, L.K.4    Kwamie, A.5    Diamandis, E.P.6
  • 34
    • 51849083426 scopus 로고    scopus 로고
    • What drives intense apoptosis resistance and propensity for necrosis in glioblastoma? A role for Bcl2L12 as a multifunctional cell death regulator
    • Stegh A. H., Chin L., Louis D. N., DePinho R. A., What drives intense apoptosis resistance and propensity for necrosis in glioblastoma? A role for Bcl2L12 as a multifunctional cell death regulator Cell Cycle 2008 7 18 2833 2839
    • (2008) Cell Cycle , vol.7 , Issue.18 , pp. 2833-2839
    • Stegh, A.H.1    Chin, L.2    Louis, D.N.3    Depinho, R.A.4
  • 35
    • 29944438881 scopus 로고    scopus 로고
    • Necrotic death as a cell fate
    • DOI 10.1101/gad.1376506
    • Zong W. X., Thompson C. B., Necrotic death as a cell fate Genes and Development 2006 20 1 1 15 (Pubitemid 43042662)
    • (2006) Genes and Development , vol.20 , Issue.1 , pp. 1-15
    • Zong, W.-X.1    Thompson, C.B.2
  • 37
    • 78650831721 scopus 로고    scopus 로고
    • Beyond effector caspase inhibition: Bcl2L12 neutralizes p53 signaling in glioblastoma
    • Stegh A. H., DePinho R. A., Beyond effector caspase inhibition: Bcl2L12 neutralizes p53 signaling in glioblastoma Cell Cycle 2011 10 1 33 38
    • (2011) Cell Cycle , vol.10 , Issue.1 , pp. 33-38
    • Stegh, A.H.1    Depinho, R.A.2
  • 42
    • 27744431949 scopus 로고    scopus 로고
    • Investigations on gossypol: Past and present developments
    • DOI 10.1517/13543784.14.11.1419
    • Dodou K., Anderson R. J., Small D. A. P., Groundwater P. W., Investigations of gossypol: past and present developments Expert Opinion on Investigational Drugs 2005 14 11 1419 1434 (Pubitemid 41601456)
    • (2005) Expert Opinion on Investigational Drugs , vol.14 , Issue.11 , pp. 1419-1434
    • Dodou, K.1
  • 44
    • 22944473652 scopus 로고    scopus 로고
    • New approaches and therapeutics targeting apoptosis in disease
    • DOI 10.1124/pr.57.2.6
    • Fischer U., Schulze-Osthoff K., New approaches and therapeutics targeting apoptosis in disease Pharmacological Reviews 2005 57 2 187 215 (Pubitemid 41043884)
    • (2005) Pharmacological Reviews , vol.57 , Issue.2 , pp. 187-215
    • Fischer, U.1    Schulze-Osthoff, K.2
  • 47
    • 78650371145 scopus 로고    scopus 로고
    • Intratumoral mediated immunosuppression is prognostic in genetically engineered murine models of glioma and correlates to immunotherapeutic responses
    • Kong L. Y., Wu A. S., Doucette T., Wei J., Priebe W., Fuller G. N., Qiao W., Sawaya R., Rao G., Heimberger A. B., Intratumoral mediated immunosuppression is prognostic in genetically engineered murine models of glioma and correlates to immunotherapeutic responses Clinical Cancer Research 2010 16 23 5722 5733
    • (2010) Clinical Cancer Research , vol.16 , Issue.23 , pp. 5722-5733
    • Kong, L.Y.1    Wu, A.S.2    Doucette, T.3    Wei, J.4    Priebe, W.5    Fuller, G.N.6    Qiao, W.7    Sawaya, R.8    Rao, G.9    Heimberger, A.B.10
  • 49
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • Bartel D. P., MicroRNAs: genomics, biogenesis, mechanism, and function Cell 2004 116 2 281 297
    • (2004) Cell , vol.116 , Issue.2 , pp. 281-297
    • Bartel, D.P.1
  • 50
    • 74049092646 scopus 로고    scopus 로고
    • Downregulations of B-cell lymphoma 2 and myeloid cell leukemia sequence 1 by microRNA 153 induce apoptosis in a glioblastoma cell line DBTRG-05MG
    • Xu J., Liao X., Wong C., Downregulations of B-cell lymphoma 2 and myeloid cell leukemia sequence 1 by microRNA 153 induce apoptosis in a glioblastoma cell line DBTRG-05MG International Journal of Cancer 2010 126 4 1029 1035
    • (2010) International Journal of Cancer , vol.126 , Issue.4 , pp. 1029-1035
    • Xu, J.1    Liao, X.2    Wong, C.3
  • 51
    • 77956178738 scopus 로고    scopus 로고
    • MiR-21 protected human glioblastoma U87MG cells from chemotherapeutic drug temozolomide induced apoptosis by decreasing Bax/Bcl-2 ratio and caspase-3 activity
    • Shi L., Chen J., Yang J., Pan T., Zhang S., Wang Z., MiR-21 protected human glioblastoma U87MG cells from chemotherapeutic drug temozolomide induced apoptosis by decreasing Bax/Bcl-2 ratio and caspase-3 activity Brain Research 2010 1352 255 264
    • (2010) Brain Research , vol.1352 , pp. 255-264
    • Shi, L.1    Chen, J.2    Yang, J.3    Pan, T.4    Zhang, S.5    Wang, Z.6
  • 54
    • 0036210180 scopus 로고    scopus 로고
    • BCL-2 family proteins modulate radiosensitivity in human malignant glioma cells
    • DOI 10.1023/A:1014448721327
    • Streffer J. R., Rimner A., Rieger J., Naumann U., Rodemann H. P., Weller M., BCL-2 family proteins modulate radiosensitivity in human malignant glioma cells Journal of Neuro-Oncology 2002 56 1 43 49 (Pubitemid 34256617)
    • (2002) Journal of Neuro-Oncology , vol.56 , Issue.1 , pp. 43-49
    • Streffer, J.R.1    Rimner, A.2    Rieger, J.3    Naumann, U.4    Rodemann, H.-P.5    Weller, M.6
  • 55
    • 80051761743 scopus 로고    scopus 로고
    • The role of Bcl-2 and its pro-survival relatives in tumourigenesis and cancer therapy
    • Kelly P. N., Strasser A., The role of Bcl-2 and its pro-survival relatives in tumourigenesis and cancer therapy Cell Death and Differentiation 2011 18 9 1414 1424
    • (2011) Cell Death and Differentiation , vol.18 , Issue.9 , pp. 1414-1424
    • Kelly, P.N.1    Strasser, A.2
  • 56
    • 34249996230 scopus 로고    scopus 로고
    • L inhibitor ABT-737
    • DOI 10.1038/sj.onc.1210166, PII 1210166
    • Lin X., Morgan-Lappe S., Huang X., Li L., Zakula D. M., Vernetti L. A., Fesik S. W., Shen Y., Seed analysis of off-target siRNAs reveals an essential role of Mcl-1 in resistance to the small-molecule Bcl-2/Bcl-XL inhibitor ABT-737 Oncogene 2007 26 27 3972 3979 (Pubitemid 46884293)
    • (2007) Oncogene , vol.26 , Issue.27 , pp. 3972-3979
    • Lin, X.1    Morgan-Lappe, S.2    Huang, X.3    Li, L.4    Zakula, D.M.5    Vernetti, L.A.6    Fesik, S.W.7    Shen, Y.8
  • 57
    • 0141869788 scopus 로고    scopus 로고
    • Expression of antisense bcl-2 cDNA abolishes tumorigenicity and enhances chemosensitivity of human malignant glioma cells
    • DOI 10.1002/jnr.10722
    • Zhu C. J., Li Y. B., Wong M. C., Expression of antisense bcl-2 cDNA abolishes tumorigenicity and enhances chemosensitivity of human malignant glioma cells Journal of Neuroscience Research 2003 74 1 60 66 (Pubitemid 37176667)
    • (2003) Journal of Neuroscience Research , vol.74 , Issue.1 , pp. 60-66
    • Zhu, C.J.1    Li, Y.B.2    Wong, M.C.3
  • 61
    • 77953230937 scopus 로고    scopus 로고
    • A genome-wide RNA interference screen reveals an essential CREB3L2-ATF5-MCL1 survival pathway in malignant glioma with therapeutic implications
    • Sheng Z., Li L., Zhu L. J., Smith T. W., Demers A., Ross A. H., Moser R. P., Green M. R., A genome-wide RNA interference screen reveals an essential CREB3L2-ATF5-MCL1 survival pathway in malignant glioma with therapeutic implications Nature Medicine 2010 16 6 671 677
    • (2010) Nature Medicine , vol.16 , Issue.6 , pp. 671-677
    • Sheng, Z.1    Li, L.2    Zhu, L.J.3    Smith, T.W.4    Demers, A.5    Ross, A.H.6    Moser, R.P.7    Green, M.R.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.