메뉴 건너뛰기




Volumn 4, Issue 1, 2012, Pages 146-150

Scorpion venom component III inhibits cell proliferation by modulating NF-κB activation in human leukemia cells

Author keywords

Cell cycle; Leukemia; Nuclear factor B; Scorpion venom

Indexed keywords

CYCLIN D1; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LUCIFERASE; SCORPION VENOM; SCORPION VENOM COMPONENT 3; UNCLASSIFIED DRUG;

EID: 84865748382     PISSN: 17920981     EISSN: 17921015     Source Type: Journal    
DOI: 10.3892/etm.2012.548     Document Type: Article
Times cited : (17)

References (31)
  • 2
    • 79957465104 scopus 로고    scopus 로고
    • Scorpion (Androctonus crassicauda) venom limits growth of transformed cells (SH-SY5Y and MCF-7) by cytotoxicity and cell cycle arrest
    • Zargan J, Sajad M, Umar S, Naime M, Ali S and Khan HA: Scorpion (Androctonus crassicauda) venom limits growth of transformed cells (SH-SY5Y and MCF-7) by cytotoxicity and cell cycle arrest. Exp Mol Pathol 91: 447-454, 2011.
    • (2011) Exp Mol Pathol , vol.91 , pp. 447-454
    • Zargan, J.1    Sajad, M.2    Umar, S.3    Naime, M.4    Ali, S.5    Khan, H.A.6
  • 3
    • 68449085749 scopus 로고    scopus 로고
    • Upregulation of PTEN involved in scorpion venom-induced apoptosis in a lymphoma cell line
    • Gao F, Li H, Chen YD, Yu XN, Wang R and Chen XL: Upregulation of PTEN involved in scorpion venom-induced apoptosis in a lymphoma cell line. Leuk Lymphoma 50: 633-641, 2009.
    • (2009) Leuk Lymphoma , vol.50 , pp. 633-641
    • Gao, F.1    Li, H.2    Chen, Y.D.3    Yu, X.N.4    Wang, R.5    Chen, X.L.6
  • 4
    • 78651307658 scopus 로고    scopus 로고
    • Scorpion (Odontobuthus doriae) venom induces apoptosis and inhibits DNA synthesis in human neuroblastoma cells
    • Zargan J, Sajad M, Umar S, Naime M, Ali S and Khan HA: Scorpion (Odontobuthus doriae) venom induces apoptosis and inhibits DNA synthesis in human neuroblastoma cells. Mol Cell Biochem 348: 173-181, 2011.
    • (2011) Mol Cell Biochem , vol.348 , pp. 173-181
    • Zargan, J.1    Sajad, M.2    Umar, S.3    Naime, M.4    Ali, S.5    Khan, H.A.6
  • 5
    • 33750435582 scopus 로고    scopus 로고
    • NF-κB and the immune response
    • Hayden MS, West AP and Ghosh S: NF-κB and the immune response. Oncogene 25: 6758-6780, 2006.
    • (2006) Oncogene , vol.25 , pp. 6758-6780
    • Hayden, M.S.1    West, A.P.2    Ghosh, S.3
  • 6
    • 85047699198 scopus 로고    scopus 로고
    • Nuclear transcription factor-kappaB as a target for cancer drug development
    • Garg A and Aggarwal BB: Nuclear transcription factor-kappaB as a target for cancer drug development. Leukemia 16: 1053-1068, 2002.
    • (2002) Leukemia , vol.16 , pp. 1053-1068
    • Garg, A.1    Aggarwal, B.B.2
  • 8
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D and Weinberg RA: The hallmarks of cancer. Cell 100: 57-70, 2000.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 9
    • 72449125362 scopus 로고    scopus 로고
    • Apoptosis induction in human leukemic cells by a novel protein Bengalin, isolated from Indian black scorpion venom: Through mitochondrial pathway and inhibition of heat shock proteins
    • Gupta SD, Gomes A, Debnath A, Saha A and Gomes A: Apoptosis induction in human leukemic cells by a novel protein Bengalin, isolated from Indian black scorpion venom: through mitochondrial pathway and inhibition of heat shock proteins. Chem Biol Interact 183: 293-303, 2010.
    • (2010) Chem Biol Interact , vol.183 , pp. 293-303
    • Gupta, S.D.1    Gomes, A.2    Debnath, A.3    Saha, A.4    Gomes, A.5
  • 10
    • 34249898393 scopus 로고    scopus 로고
    • Indian black scorpion (Heterometrus bengalensis Koch) venom induced antiproliferative and apoptogenic activity against human leukemic cell lines U937 and K562
    • Das Gupta S, Debnath A, Saha A, Giri B, Tripathi G, Vedasiromoni JR and Gomes A: Indian black scorpion (Heterometrus bengalensis Koch) venom induced antiproliferative and apoptogenic activity against human leukemic cell lines U937 and K562. Leukemia Res 31: 817-825, 2007.
    • (2007) Leukemia Res , vol.31 , pp. 817-825
    • Das Gupta, S.1    Debnath, A.2    Saha, A.3    Giri, B.4    Tripathi, G.5    Vedasiromoni, J.R.6    Gomes, A.7
  • 13
    • 20444489265 scopus 로고    scopus 로고
    • Scorpion venom induces glioma cell apoptosis in vivo and inhibits glioma tumor growth in vitro
    • Wang WX and Ji YH: Scorpion venom induces glioma cell apoptosis in vivo and inhibits glioma tumor growth in vitro. J Neurooncol 73: 1-7, 2005.
    • (2005) J Neurooncol , vol.73 , pp. 1-7
    • Wang, W.X.1    Ji, Y.H.2
  • 14
    • 77958513924 scopus 로고    scopus 로고
    • Apoptogenic peptides from Tityus discrepans scorpion venom acting against the SKBR3 breast cancer cell line
    • D'Suze G, Rosales A, Salazar V and Sevcik C: Apoptogenic peptides from Tityus discrepans scorpion venom acting against the SKBR3 breast cancer cell line. Toxicon 56: 1497-1505, 2010.
    • (2010) Toxicon , vol.56 , pp. 1497-1505
    • D'Suze, G.1    Rosales, A.2    Salazar, V.3    Sevcik, C.4
  • 15
    • 78651326954 scopus 로고    scopus 로고
    • Anti-proliferation effect of polypeptide extracted from scorpion venom on human prostate cancer cells in vitro
    • Zhang YY, Wu LC, Wang ZP, Wang ZX, Jia Q, Jiang GS and Zhang WD: Anti-proliferation effect of polypeptide extracted from scorpion venom on human prostate cancer cells in vitro. J Clin Med Res 1: 24-31, 2009.
    • (2009) J Clin Med Res , vol.1 , pp. 24-31
    • Zhang, Y.Y.1    Wu, L.C.2    Wang, Z.P.3    Wang, Z.X.4    Jia, Q.5    Jiang, G.S.6    Zhang, W.D.7
  • 16
    • 72449157185 scopus 로고    scopus 로고
    • In vitro anticancer effect of scorpion Leiurus quinquestriatus and Egyptian Cobra venom on human breast and prostate cancer cell lines
    • Omran MAA: In vitro anticancer effect of scorpion Leiurus quinquestriatus and Egyptian Cobra venom on human breast and prostate cancer cell lines. J Med Sci 3: 66-86, 2003.
    • (2003) J Med Sci , vol.3 , pp. 66-86
    • Omran, M.A.A.1
  • 17
    • 2342464085 scopus 로고    scopus 로고
    • The two NF-kappaB activation pathways and their role in innate and adaptive immunity
    • Bonizzi G and Karin M: The two NF-kappaB activation pathways and their role in innate and adaptive immunity. Trends Immunol 25: 280-288, 2004.
    • (2004) Trends Immunol , vol.25 , pp. 280-288
    • Bonizzi, G.1    Karin, M.2
  • 18
    • 50049112829 scopus 로고    scopus 로고
    • Role of nuclear IkappaB proteins in the regulation of host immune responses
    • Yamamoto M and Takeda K: Role of nuclear IkappaB proteins in the regulation of host immune responses. J Infect Chemother 14: 265-269, 2008.
    • (2008) J Infect Chemother , vol.14 , pp. 265-269
    • Yamamoto, M.1    Takeda, K.2
  • 19
    • 76949084622 scopus 로고    scopus 로고
    • TNF-alpha/NF-kappaB/Snail pathway in cancer cell migration and invasion
    • Wu Y and Zhou BP: TNF-alpha/NF-kappaB/Snail pathway in cancer cell migration and invasion. Br J Cancer 102: 639-644, 2010.
    • (2010) Br J Cancer , vol.102 , pp. 639-644
    • Wu, Y.1    Zhou, B.P.2
  • 20
    • 53949090765 scopus 로고    scopus 로고
    • NF-kappaB signaling pathway and its therapeutic implications in human diseases
    • Sarkar FH, Li Y, Wang Z and Kong D: NF-kappaB signaling pathway and its therapeutic implications in human diseases. Int Rev Immunol 27: 293-319, 2008.
    • (2008) Int Rev Immunol , vol.27 , pp. 293-319
    • Sarkar, F.H.1    Li, Y.2    Wang, Z.3    Kong, D.4
  • 21
    • 33646581238 scopus 로고    scopus 로고
    • Classical and alternative NF-κB activation pathways and their roles in lymphoid malignancies
    • Nishikori M: Classical and alternative NF-κB activation pathways and their roles in lymphoid malignancies. J Clin Exp Hematopathol 45: 15-24, 2005.
    • (2005) J Clin Exp Hematopathol , vol.45 , pp. 15-24
    • Nishikori, M.1
  • 22
    • 72149129447 scopus 로고    scopus 로고
    • A small molecule inhibitor of NF-kappaB, dehydroxymethylepoxyquinomicin (DHMEQ), suppresses growth and invasion of nasopharyngeal carcinoma (NPC) cells
    • Wong JH, Lui VW, Umezawa K, Ho Y, Wong EY, Ng MH, Cheng SH, Tsang CM, Tsao SW and Chan AT: A small molecule inhibitor of NF-kappaB, dehydroxymethylepoxyquinomicin (DHMEQ), suppresses growth and invasion of nasopharyngeal carcinoma (NPC) cells. Cancer Lett 287: 23-32, 2010.
    • (2010) Cancer Lett , vol.287 , pp. 23-32
    • Wong, J.H.1    Lui, V.W.2    Umezawa, K.3    Ho, Y.4    Wong, E.Y.5    Ng, M.H.6    Cheng, S.H.7    Tsang, C.M.8    Tsao, S.W.9    Chan, A.T.10
  • 23
    • 47249161539 scopus 로고    scopus 로고
    • Anthrax lethal toxin enhances TNF-induced endothelial VCAM-1 expression via an IFN regulatory factor-1-dependent mechanism
    • Warfel JM and D'Agnillo F: Anthrax lethal toxin enhances TNF-induced endothelial VCAM-1 expression via an IFN regulatory factor-1-dependent mechanism. J Immunol 180: 7516-7524, 2008.
    • (2008) J Immunol , vol.180 , pp. 7516-7524
    • Warfel, J.M.1    D'Agnillo, F.2
  • 24
    • 78549245097 scopus 로고    scopus 로고
    • NF-κB mediates aberrant activation of HIF-1 in malignant lymphoma
    • Qiao Q, Nozaki Y, Sakoe K, Komatsu N and Kirito K: NF-κB mediates aberrant activation of HIF-1 in malignant lymphoma. Exp Hematol 38: 1199-1208, 2010.
    • (2010) Exp Hematol , vol.38 , pp. 1199-1208
    • Qiao, Q.1    Nozaki, Y.2    Sakoe, K.3    Komatsu, N.4    Kirito, K.5
  • 25
    • 34547785584 scopus 로고    scopus 로고
    • Human chorionic gonadotrophin attenuates NF-kappaB activation and cytokine expression of endometriotic stromal cells
    • Huber AV, Saleh L, Prast J, Haslinger P and Knöfler M: Human chorionic gonadotrophin attenuates NF-kappaB activation and cytokine expression of endometriotic stromal cells. Mol Hum Reprod 13: 595-604, 2007.
    • (2007) Mol Hum Reprod , vol.13 , pp. 595-604
    • Huber, A.V.1    Saleh, L.2    Prast, J.3    Haslinger, P.4    Knöfler, M.5
  • 26
    • 0034084163 scopus 로고    scopus 로고
    • Phosphorylation meets ubiquitination: The control of NF-kB activity
    • Karin M and Ben-Neriah Y: Phosphorylation meets ubiquitination: the control of NF-kB activity. Annu Rev Immunol 18: 621-663, 2000.
    • (2000) Annu Rev Immunol , vol.18 , pp. 621-663
    • Karin, M.1    Ben-Neriah, Y.2
  • 27
    • 0035929670 scopus 로고    scopus 로고
    • Cytokine-induced activation of nuclear factor-kappa B is inhibited by hydrogen peroxide through oxidative inactivation of IkappaB kinase
    • Korn SH, Wouters EF, Vos N and Janssen-Heininger YM: Cytokine-induced activation of nuclear factor-kappa B is inhibited by hydrogen peroxide through oxidative inactivation of IkappaB kinase. J Biol Chem 276: 35693-35700, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 35693-35700
    • Korn, S.H.1    Wouters, E.F.2    Vos, N.3    Janssen-Heininger, Y.M.4
  • 28
    • 3843052483 scopus 로고    scopus 로고
    • Nuclear factor-κB: Its role in health and disease
    • Kumar A, Takada Y, Boriek AM and Aggarwal BB: Nuclear factor-κB: its role in health and disease. J Mol Med 82: 434-448, 2004.
    • (2004) J Mol Med , vol.82 , pp. 434-448
    • Kumar, A.1    Takada, Y.2    Boriek, A.M.3    Aggarwal, B.B.4
  • 29
    • 37549004392 scopus 로고    scopus 로고
    • Nuclear factor-kappaB activation: From bench to bedside
    • Sethi G, Sung B and Aggarwal BB: Nuclear factor-kappaB activation: from bench to bedside. Exp Biol Med (Maywood) 233: 21-31, 2008.
    • (2008) Exp Biol Med (Maywood) , vol.233 , pp. 21-31
    • Sethi, G.1    Sung, B.2    Aggarwal, B.B.3
  • 30
    • 23844490779 scopus 로고    scopus 로고
    • Overexpression of cyclin D1 promotes tumor cell growth and confers resistance to cisplatinmediated apoptosis in an elastase-myc transgene-expressing pancreatic tumor cell line
    • Biliran H Jr, Wang Y, Banerjee S, Xu H, Heng H, Thakur A, cfBollig A, Sarkar FH and Liao JD: Overexpression of cyclin D1 promotes tumor cell growth and confers resistance to cisplatinmediated apoptosis in an elastase-myc transgene-expressing pancreatic tumor cell line. Clin Cancer Res 11: 6075-6086, 2005.
    • (2005) Clin Cancer Res , vol.11 , pp. 6075-6086
    • Biliran Jr., H.1    Wang, Y.2    Banerjee, S.3    Xu, H.4    Heng, H.5    Thakur, A.6    Cfbollig, A.7    Sarkar, F.H.8    Liao, J.D.9
  • 31
    • 77951049854 scopus 로고    scopus 로고
    • Noscapine, a benzylisoquinoline alkaloid, sensitizes leukemic cells to chemotherapeutic agents and cytokines by modulating the NF-kappaB signaling pathway
    • Sung B, Ahn KS and Aggarwal BB: Noscapine, a benzylisoquinoline alkaloid, sensitizes leukemic cells to chemotherapeutic agents and cytokines by modulating the NF-kappaB signaling pathway. Cancer Res 70: 3259-3268, 2010.
    • (2010) Cancer Res , vol.70 , pp. 3259-3268
    • Sung, B.1    Ahn, K.S.2    Aggarwal, B.B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.