Cluster of differentiation 38 (CD38) mediates bile acid-induced acinar cell injury and pancreatitis through cyclic ADP-ribose and intracellular calcium release

Journal of Biological Chemistry

Volumn 288, Issue 38, 2013, Pages 27128-27137

  Orabi, Abrahim I ^a   Muili, Kamaldeen A ^a   Javed, Tanveer A ^a   Jin, Shunqian ^a   Jayaraman, Thottala ^a   Lund, Frances E ^b   Husain, Sohail Z ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b University of Alabama at Birmingham   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE PANCREATITIS; CRITICAL FEATURES; CYCLIC ADP-RIBOSE (CADPR); INTRACELLULAR CA; INTRACELLULAR CALCIUM; LACTATE DEHYDROGENASE; PANCREATIC ACINAR CELLS; RYANODINE RECEPTORS;

BODY FLUIDS; CALCIUM; CELLS; CYTOLOGY; MAMMALS; PLANTS (BOTANY);

CELL SIGNALING;

ADENOSINE DIPHOSPHATE RIBOSYL CYCLASE; BILE ACID; CALCIUM; CLUSTER OF DIFFERENTIATION 38 PROTEIN; CYCLIC ADENOSINE DIPHOSPHATE RIBOSE; ENZYME INHIBITOR; NICOTINAMIDE; PROPIDIUM IODIDE; TAUROLITHOCHOLIC ACID; UNCLASSIFIED DRUG;

ACINAR CELL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CALCIUM TRANSPORT; CD38 GENE; CELL DAMAGE; CELL ISOLATION; CONTROLLED STUDY; CULTURE MEDIUM; CYTOSOL; EXTRACELLULAR CALCIUM; GENE; GENE DELETION; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; MOUSE; NONHUMAN; PANCREATITIS; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

BILE ACID; CALCIUM SIGNALING; CD38; CYCLIC ADP-RIBOSE; NAADP; PANCREAS; RYANODINE RECEPTOR;

ACINAR CELLS; ANIMALS; ANTIGENS, CD38; BILE ACIDS AND SALTS; CALCIUM; CALCIUM SIGNALING; CYCLIC ADP-RIBOSE; HUMANS; L-LACTATE DEHYDROGENASE; MEMBRANE GLYCOPROTEINS; MICE; MICE, KNOCKOUT; PANCREATITIS;

EID: 84884544733     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.494534     Document Type: Article

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