Mice deficient for the ecto-nicotinamide adenine dinucleotide glycohydrolase CD38 exhibit altered humoral immune responses

Blood

Volumn 92, Issue 4, 1998, Pages 1324-1333

  Cockayne, Debra A ^a   Muchamuel, Tony ^b   Grimaldi, J Christopher ^b   Muller Steffner, Hélène ^b   Randall, Troy D ^b   Lund, Frances E ^b   Murray, Richard ^b   Schuber, Francis ^b   Howard, Maureen C ^b  

^a ROCHE BIOSCIENCE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE RIBOSE; GLYCOSIDASE; NICOTINAMIDE ADENINE DINUCLEOTIDE;

ANTIBODY RESPONSE; ANTIGEN ANTIBODY REACTION; ARTICLE; HEMATOPOIETIC STEM CELL; HUMORAL IMMUNITY; IMMUNE RESPONSE; IMMUNOREGULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 0032529498     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v92.4.1324.416k26_1324_1333     Document Type: Article

References (63)

1. Price SR, Pekala PH: Pyridine Nucleotide Coenzymes: Chemical, Biological, and Medical Aspects (vol 2B). New York, NY, Wiley-Interscience, 1987
2. Howard M, Grimaldi JC, Bazan JF, Lund FE, Santos-Argumedo L, Parkhouse RME, Walseth TF, Lee HC: Formation and hydrolysis of cyclic ADP-ribose catalyzed by lymphocyte antigen CD38. Science 262:1056, 1993
3. + glycohydrolase, ADP-ribosyl cyclase and cyclic ADP-ribosyl hydrolase activities at the outer surface of human erythrocytes. Biochem Biophys Res Comm 196:1459, 1993
4. Takasawa S, Togho A, Noguchi N, Koguma T, Nata K, Sugimoto T, Yonekura H, Okamoto H: Synthesis and hydrolysis of cyclic ADP-ribose by human leukocyte antigen CD38 and inhibition of the hydrolysis by ATP. J Biol Chem 268:26052, 1993
5. Kim H, Jacobson EL, Jacobson MK: Synthesis and degradation of cyclic ADP-ribose by NAD glycohydrolases. Science 261:1330, 1993
6. + glycohydrolase. J Biol Chem 271:23967, 1996
7. Jacobson MK, Jacobson EL: ADP-Ribose Transfer Reactions: Mechanisms and Biological Significance. New York, NY, Springer-Verlag, 1989
8. Hellmich MR, Strumwasser F: Purification and characterization of a molluscan egg-specific NADase, a second-messenger enzyme. Cell Regul 2:193, 1991
9. + into a calcium-mobilizing metabolite. Cell Regul 2:203, 1991
10. 2+ release in sea urchin egg homogenates: Modulation by cyclic ADP-ribose. Science 253:1143, 1991
11. Kalo I, Takasawa S, Akabane A, Tanaka O, Abe H, Takamura T, Suzuki Y, Nata K, Yonekura H, Yoshimoto T, Okamoto H: Regulatory role of CD38 (ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase) in insulin secretion by glucose in pancreatic β cells. J Biol Chem 270:30045, 1995
12. 2+-dependent currents in cultured rat dorsal root ganglion neurones by a sperm factor and cyclic ADP-ribose. Mol Biol Cell 3:1415, 1992
13. 2+ entry into bullfrog sympathetic neurons. Neuron 12:1073, 1994
14. Ebihara S, Sasaki T, Hida W, Kikuchi Y, Oshiro T, Shimura S, Takasawa S, Okamoto H, Nishiyama A, Akaike N, Shirato K: Role of cyclic ADP-ribose in ATP-activated potassium currents in alveolar macrophages. J Biol Chem 272:16023, 1997
15. Lund F, Solvason N, Grimaldi JC, Parkhouse RME, Howard M: Murine CD38: An immunoregulatory ectoenzyme. Immunol Today 16:469, 1995
16. Dong C, Wang J, Neame P, Cooper MD: The murine BP-3 gene encodes a relative of the CD38/NAD glycohydrolase family. Int Immunol 6:1353, 1994
17. Itoh M, Ishihara K, Tomizawa H, Tanaka H, Kobune Y, Ishikawa J, Kaisho T, Hirano T: Molecular cloning of murine BST-1 having homology with CD38 and Aplysia ADP-ribosyl cyclase. Biochem Biophys Res Comm 203:1309, 1994
18. + cells in peripheral lymph nodes of DA rats. Transplant Proc 19:3157, 1987
19. Reinherz EL, Kung PC, Goldstein G, Levey RH, Schlossman SF: Discrete stages of human intrathymic differentiation: Analysis of normal thymocytes and leukemic lymphoblasts of T-cell lineage. Proc Natl Acad Sci USA 77:1588, 1980
20. Malavasi F, Funaro A, Roggero S, Horenstein A, Calosso L, Mehta K: Human CD38: A glycoprotein in search of a function. Immunol Today 15:95, 1994
21. Mizuguchi M, Otsuka N, Sato M, Ishii Y, Kon S, Yamada M, Nishina H, Katada T Ikeda K: Neuronal localization of CD38 in the human brain. Brain Res 697:235, 1995
22. Randall TD, Lund FE, Howard MC, Weissman IL: Expression of CD38 defines a population of long-term reconstituting hematopoietic stem cells. Blood 87:4057, 1996
23. Marinov J, Koubek K, Stary J: Immunophenotypic significance of the "lymphoid" CD38 antigen in myeloid blood malignancies. Neoplasma 40:355, 1993
24. Kramer G, Steiner G, Fodinger D, Fiebiger E, Rappersberger C, Binder S, Hofbauer J, Marberger M: High expression of a CD38-like molecule in normal prostatic epithelium and its differential loss in benign and malignant disease. J Urol 154:636, 1995
25. + cell counts and proliferation to mitogens. Cell Immunol 150:72, 1993
26. + T cell levels: Results of 6 years of follow-up. J Acquir Immune Defic Syndr 6:904, 1993
27. Ausiello CM, Urbani F, la Sala A, Furano A, Malavasi F: CD38 ligation induces discrete cytokine mRNA expression in human cultured lymphocytes. Eur J Immonol 25:1477, 1995
28. Kumagai M, Coustan-Smith E, Murray DJ, Silvennoinen O, Murti KG, Evans WE, Malavasi F, Campana D: Ligation of CD38 suppresses human B lymphopoiesis. J Exp Med 181:1101, 1995
29. Santos-Argumedo L, Teixeira C, Preece G, Kirkham PA, Parkhouse RME: A B lymphocyte surface molecule mediating activation and protection from apoptosis via calcium channels. J Immunol 151:3119, 1993
30. Lund FE, Yu N, Kim K-M, Reth M, Howard MC: Signaling through CD38 augments B cell antigen receptor (BCR) responses and is dependent on BCR expression. J Immunol 157:1455, 1996
31. Lund FE, Cockayne DA, Randall TD, Solvason N, Schuber F, Howard MC: CD38: A new paradigm in lymphocyte activation and signal transduction. Immunol Rev 161:79, 1998
32. Carter RH, Fearon DT: CD19: Lowering the threshold for antigen receptor stimulation of B lymphocytes. Science 256:105, 1992
33. Yasue T, Nishizumi H, Aizawa S, Yamamoto T, Miyake K, Mizoguchi C, Uehara S, Kikuchi Y, Takatsu K: A critical role for Lyn and Fyn for B cell responses to CD38 ligation and interleukin 5. Proc Natl Acad Sci USA 94:10307, 1997
34. Shubinsky G, Schlesinger M: The CD38 lymphocyte differentiation marker: New insight into its ectoenzyme activity and its role as a signal transducer. Immunity 7:315, 1997
35. Zubiaur M, Izquierdo M, Terhorst C, Malavasi F, Sancho J: CD38 ligation results in activation of the Raf-1/mitogen-activated protein kinase and the CD3-ζ/ζ-associated protein-70 signaling pathways in Jurkat T lymphocytes. J Immunol 159:193, 1997
36. Kitanaka A, Ito C, Coustan-Smith E, Campana D: CD38 ligation in human B cell progenitors triggers tryrosine phosphorylation of CD19 and association of CD 19 with lyn and phosphatidylinositol 3-kinase. J Immunol 159:184, 1997
37. Tsujimoto N, Kontani K, Inoue S, Hoshino S, Hazeki O, Malavasi F, Katada T: Potentiation of chemotactic peptide-induced Superoxide generation by CD38 ligation in human myeloid cell lines. J Biochem 121:949, 1997
38. + glycohydrolase, an ecto-enzyme of calf spleen cells. Biochem J 212:459, 1983
39. Tarnus C, Schuber F: Application of linear free-energy relationships to the mechanistic probing of nonenzymatic and NAD-glycohydrolase-catalyzed hydrolysis of pyridine dinucleotides. Bioorg Chem 15:31, 1987
40. + as substrates for a sensitive fluorimetric assay of nucleotide pyrophosphatase. Biochem J 223:715, 1984
41. Harrison DE: Competitive repopulation: A new assay for long-term stem cell functional capacity. Blood 55:77, 1980
42. Savelkoul HFJ, Seymour BWP, Sullivan L, Coffman RL: IL-4 can correct defective IgE production in SJA/9 mice. J Immunol 146:1801, 1991
43. Roes J, Rajewsky K: Immunoglobulin D (IgD)-deficient mice reveal an auxiliary receptor function for IgD in antigen-mediated recruitment of B cells. J Exp Med 177:45, 1993
44. Stohrer R, Lee MC, Kearney JF: Analysis of the anti-alpha 1 leads to a 3 dextran response with monoclonal anti-idiotype antibodies. J Immunol 131:1375, 1983
45. Grimaldi JC, Balasubramanian S, Kabra NH, Shanafelt A, Bazan JF, Zurawski G, Howard MC: CD38-mediated ribosylation of proteins. J Immunol 155:811, 1995
46. Takada T, Iida K, Moss J: Expression of NAD glycohydrolase activity by rat mammary adenocarcinoma cells transformed with rat T cell alloantigen RT6.2. J Biol Chem 269:9420, 1994
47. Haag F, Andresen V, Karsten S, Koch-Nolte F, Thiele H-G: Both allelic forms of the rat T cell differentiation marker RT6 display nicotinamide adenine dinucteotide (NAD)-glycohydrolase activity, yet only RT6.2 is capable of automodification upon incubation with NAD. Eur J Immunol 25:2355, 1995
48. Koch-Nolte F, Petersen D, Balasubramanian S, Haag F, Kahlke D, Wilier T, Kastelein R, Bazan F, Thiele HG: Mouse T cell membrane proteins Rt6-l and Rt6-2 are arginine/protein mono(ADPribosyl)transferases and share secondary structure motifs with ADP-ribosylating bacterial toxins. J Biol Chem 271:7686, 1996
49. - progenitor cells. Blood 77:1218, 1991
50. + human fetal liver progenitors with a high proliferative potential. Blood 83:3170, 1994
51. - hematopoietic stem cells. Blood 83:1515, 1994
52. - thymocytes. Int Immunol 7:213, 1995
53. Allison AC, Byars NE: Immunological adjuvants: Desirable properties and side effects. Mol Immunol 28:279, 1991
54. + B cells upon transfer of peritoneal cells into allotype-congenic newborn mice. Eur J Immunol 17:521, 1987
55. Mond JJ, Lees A, Snapper CM: T cell-independent antigens type 2. Annu Rev Immunol 13:655, 1995
56. Lund FE, Solvason NW, Cooke MP, Heath AW, Grimaldi JC, Parkhouse RME, Goodnow CC, Howard MC: Signaling through murine CD38 is impaired in antigen receptor unresponsive B cells. Eur J Immunol 25:1338, 1995
57. Rothstein TL, Kolber DL: Anti-Ig antibody inhibits the phorbol ester-induced stimulation of peritoneal B cells. J Immunol 141:4089, 1988
58. Silvennoinen O, Nishigaki H, Kitanaka A, Kumagai M, Ito C, Malavassi F, Lin Q, Conley ME, Campana D: CD38 signal transduction in human B cell precursors. Rapid induction of tyrosine phosphorylation, activation of syk tyrosine kinase, and phosphorylation of phospholipase C-gamma and phosphatidylinositol 3-kinase. J Immunol 156: 100, 1996
59. Kurosaki T: Molecular mechanisms in B cell antigen receptor signaling. Curr Opin Immunol 9:309, 1997
60. Birkeland ML, Monroe JG: Biochemistry of antigen receptor signaling in mature and developing B lymphocytes. Crit Rev Immunol 17:353, 1997
61. Engel P, Zhou L-J, Ord DC, Sato S, Koller B, Tedder TF: Abnormal B lymphocyte development, activation, and differentiation in mice that lack or overexpress the CD19 signal transduction molecule. Immunity 3:39, 1995
62. Rickert RC, Rajewsky K, Roes J: Impairment of T-cell-dependent B-cell responses and B-1 cell development in CD 19-deficient mice. Nature 376:352, 1995
63. Coffman RL, Seymour BW, Lebman DA, Hiraki DD, Christiansen JA, Shrader B, Cherwinski HM, Savelkoul HF, Finkelman FD, Bond MW, Mosmann TR: The role of helper T cell products in mouse B cell differentiation and isotype regulation. Immunol Rev 102:5, 1988