Calcium wave propagation in pancreatic acinar cells: Functional interaction of inositol 1,4,5-trisphosphate receptors, ryanodine receptors, and mitochondria

Journal of General Physiology

Volumn 116, Issue 4, 2000, Pages 547-559

  Straub, Stephen V ^a   Giovannucci, David R ^a   Yule, David I ^a  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

Author keywords

Calcium dynamics; Digital imaging; Exocrine cells; Flash photolysis; Intracellular signaling

Indexed keywords

RYANODINE RECEPTOR;

ACINAR CELL; ANIMAL TISSUE; ARTICLE; CALCIUM TRANSPORT; CELL COMMUNICATION; MOUSE; NONHUMAN; PANCREAS SECRETION;

ANIMALS; CALCIUM; CALCIUM CHANNELS; CALCIUM SIGNALING; CARBONYL CYANIDE P-TRIFLUOROMETHOXYPHENYLHYDRAZONE; ENDOPLASMIC RETICULUM; INOSITOL 1,4,5-TRISPHOSPHATE; MICE; MITOCHONDRIA; PANCREAS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RYANODINE; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; UNCOUPLING AGENTS;

EID: 0033772282     PISSN: 00221295     EISSN: None     Source Type: Journal    
DOI: 10.1085/jgp.116.4.547     Document Type: Article

References (42)

1. Range of messenger action of calcium ion and inositol 1,4,5-trisphosphate
2. Inositol trisphosphate and calcium signalling
3. 2+-signalling patterns by NAADP in pancreatic acinar cells
4. Calcium signalling
5. 2+](i) elevations in sympathetic neurons
6. Quasi-synaptic calcium signal transmission between endoplasmic reticulum and mitochondria
7. 3H]ryanodine-binding sites
8. Contributions of mitochondria to animal physiology: From homeostatic sensor to calcium signalling and cell death
9. 2+ with high affinity and releases it rapidly upon photolysis
10. 2+ indicators with greatly improved fluorescence properties
11. Mitochondrial calcium transport: Physiological and pathological relevance
12. 2+
13. 2+ spikes regulating distinct cellular functions in pancreatic acinar cells
14. 2+ spikes by inositol trisphosphate in pancreatic acinar cells
15. 2+ gradients triggering unidirectional fluid secretion from exocrine pancreas
16. 2+ waves and oscillations in exocrine pancreas
17. 2+ signals in mouse pancreatic acinar cells
18. 2+ release channel complex of skeletal muscle sarcoplasmic reticulum. Evidence for a cooperatively coupled, negatively charged homotetramer
19. 2+](i) waves
20. Expression and subcellular localization of the ryanodine receptor in rat pancreatic acinar cells
21. Positive cooperativity of ryanodine binding to the calcium release channel of sarcoplasmic reticulum from heart and skeletal muscle
22. Elevation of mitochondrial calcium by ryanodine-sensitive calcium-induced calcium-release
23. 2+ wave propagation in pancreatic acinar cells
24. 2+ wave trigger zone of pancreatic acinar cells
25. Mitochondria and neuronal survival
26. 2+ concentrations in the cytosol and the lumen of the endoplasmic reticulum in pancreatic acinar cells
27. 2+ responses
28. 2+ release channels
29. Calcium signal transmission between ryanodine receptors and mitochondria
30. 2+-dependent exocytosis in pancreatic beta cells
31. 2+ oscillations in exocrine cells evoked by agonists and inositol trisphosphate
32. 2+ signals
33. 2+ signals in exocrine acinar cells analysed by digital image microscopy
34. Action of secretagogues on a new preparation of functionally intact, isolated pancreatic acini
35. RGS proteins determine signaling specificity of Gq-coupled receptors
36. Oscillations of cytosolic calcium in single pancreatic acinar cells stimulated by acetylcholine
37. Stimulus-secretion coupling in the pancreatic acinus
38. Evidence that zymogen granules are not a physiologically relevant calcium pool. Defining the distribution of inositol 1,4,5-trisphosphate receptors in pancreatic acinar cells
39. 2+
40. 2+ release in rat parotid acinar cells
41. Ryanodine and inositol trisphosphate receptors are differentially distributed and expressed in rat parotid gland