FXR mediates a chromatin looping in the GR promoter thus promoting the resolution of colitis in rodents

Pharmacological Research

Volumn 77, Issue , 2013, Pages 1-10

  Renga, Barbara ^a   D'Amore, Claudio ^a   Cipriani, Sabrina ^a   Mencarelli, Andrea ^a   Carino, Adriana ^a   Sepe, Valentina ^b   Zampella, Angela ^b   Distrutti, Eleonora ^c   Fiorucci, Stefano ^a  

^a UNIVERSITY OF PERUGIA   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^c SANTA MARIA DELLA MISERICORDIA HOSPITAL   (Italy)

Author keywords

Chromatin looping; Colitis; FXR; GR; Intestinal immunity

Indexed keywords

DEXAMETHASONE; FARNESOID X RECEPTOR; GLUCOCORTICOID; MIFEPRISTONE; 6-ETHYLCHENODEOXYCHOLIC ACID; ANTIINFLAMMATORY AGENT; CELL RECEPTOR; CHENODEOXYCHOLIC ACID; CHROMATIN; FARNESOID X-ACTIVATED RECEPTOR; GLUCOCORTICOID RECEPTOR; TRINITROBENZENESULFONIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CHROMATIN; COLITIS; CONTROLLED STUDY; DNA RESPONSIVE ELEMENT; GENETIC TRANSCRIPTION; INNATE IMMUNITY; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; SIGNAL TRANSDUCTION; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL CULTURE; CHEMISTRY; GENETICS; HUMAN; KNOCKOUT MOUSE; METABOLISM;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELLS, CULTURED; CHENODEOXYCHOLIC ACID; CHROMATIN; COLITIS; DEXAMETHASONE; HUMANS; MICE; MICE, KNOCKOUT; MIFEPRISTONE; PROMOTER REGIONS, GENETIC; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, GLUCOCORTICOID; RESPONSE ELEMENTS; TRINITROBENZENESULFONIC ACID;

EID: 84884539771     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2013.08.008     Document Type: Article

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