Evaluation of PEG and mPEG-co-(PGA-co-PDL) microparticles loaded with sodium diclofenac

Saudi Pharmaceutical Journal

Volumn 21, Issue 4, 2013, Pages 387-397

  Tawfeek, Hesham M ^a  

^a Assiut University   (Egypt)

Author keywords

Lung delivery; Microparticles; PEG co polymers; PGA co PDL; Sodium diclofenac

Indexed keywords

COPOLYMER; DICLOFENAC; MACROGOL; POLY(ETHYLENE GLYCOL METHYL ETHER) POLY(GYLCEROL ADIPATE CO OMEGA PENTADECALACTONE); POLY(ETHYLENE GLYCOL) POLY(GYLCEROL ADIPATE CO OMEGA PENTADECALACTONE); POLYESTER; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG;

AEROSOL; ARTICLE; CATALYSIS; CELL VIABILITY; CONTROLLED STUDY; DENSITY; DRUG DELIVERY SYSTEM; EMULSION; ENCAPSULATION; HUMAN; HUMAN CELL; IN VITRO STUDY; MORPHOLOGY; PARTICLE SIZE; POLYMERIZATION; SPRAY DRYING; SUSTAINED RELEASE PREPARATION; SYNTHESIS; ZETA POTENTIAL;

EID: 84884533949     PISSN: 13190164     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jsps.2012.11.006     Document Type: Article

References (57)

1. Ahsan F., Rivas I.P., Khan M.A., Torres Suárez A.I. Targeting to macrophages: role of physicochemical properties of particulate carriers-liposomes and microspheres-on the phagocytosis by macrophages. J. Controlled Release 2002, 79:29-40.
2. Alder M., Unger M., Lee G. Surface composition of spray dried particles of bovine serum albumin/trehalose/surfactant. Pharm. Res. 2000, 17:863-870.
3. Batycky R.P., Hanes J., Langer R., Edwards D.A. A theoretical model of erosion and macromolecular drug release from biodegrading microspheres. J. Pharm. Sci. 1997, 86:1464-1477.
4. Bean H.S., Beckett A.H., Carless J.E. Advances in Pharmaceutical Sciences 1967, vol. 2. Academic Press, London, pp. 181-221.
5. Bentley M.D., Bossard M.J., Burton K.W., Viegas T.X. Poly(ethylene) glycol conjugates of biopharmaceuticals in drug delivery. Mod. Biopharm. 2005, 4:1393-1418.
6. Bosquillon C., Préat V., Vanbever R. Pulmonary delivery of growth hormone using dry powders and visualization of its local fate in rats. J. Controlled Release 2004, 96:233-244.
7. Canal-Raffin M., L'Azou B., Martinez B., Sellier E., Fawaz F., Robinson P., et al. Physicochemical characteristics and bronchial epithelial cell cytotoxicity of Folpan 80 WG(R) and Myco 500(R), two commercial forms of folpet. Part Fibre Toxicol. 2007, 8(4):1743-89778.
8. Castellanos I.J., Flores G., Griebenow K. Effect of the molecular weight of poly(ethylene glycol) used as emulsifier on alpha-chymotrypsin stability upon encapsulation in PLGA microspheres. J. Pharm. Pharmacol. 2005, 57:1261-1269.
9. Cheng J., Teply B.A., Sherifi I., Sung J., Luther G., Gu F.X., Levy-Nissenbaum E., Radovic-Moreno A.F., Langer R., Farokhzad O.C. Formulation of functionalized PLGA-PEG nanoparticles for in vivo targeted drug delivery. Biomaterials 2007, 28:869-876.
10. Chew N.Y.K., Shekunov B.Y., Tong H.H.Y., Chow A.H.L., Savage C., Wu J., Chan H.K. Effect of amino acids on the dispersion of disodium cromoglycate powders. J. Pharm. Sci. 2005, 94:2289-2300.
11. Chew N.Y.K., Tang P., Chan H.K., Raper J.A. How much particle surface corrugation is sufficient to improve aerosol performance of powders?. Pharm. Res. 2005, 22:148-152.
12. Corrigan O.I. Thermal-analysis of spray-dried products. Thermochim. Acta 1995, 24:245-258.
13. Donald E., Owens I.I.I., Nicholas A. Peppas Opsonization, biodistribution, and pharmacokinetics of polymeric nanoparticles. Int. J. Pharm. 2006, 307:93-102.
14. Dong Y.C., Feng S.S. Methoxy poly(ethylene glycol)-poly(lactide) (MPEGPLA) nanoparticles for controlled delivery of anticancer drugs. Biomaterials 2004, 25:2843-2849.
15. Dorati R., Genta I., Montanari L., Cilurzo F., Buttafava A., Faucitano A., Conti B. The effect of [gamma]-irradiation on PLGA/PEG microspheres containing ovalbumin. J. Controlled. Release 2005, 107:78-90.
16. Edlund U., Albertsson A.C. Degradable polymer microspheres for controlled drug delivery. Adv. Polym. Sci. 2002, 157:67-112.
17. Edwards D.A., Hanes J., Caponetti G., Hrkach J., BenJebria A., Eskew M.L., et al. Large porous particles for pulmonary drug delivery. Science 1997, 276:1868-1871.
18. Feddah M.R., Brown K.F., Gipps E.M., Davies N.M. In-vitro characterisation of metered dose inhaler versus dry powder inhaler glucocorticoid products: influence of inspiratory flow rates. J. Pharm. Pharm. Sci. 2000, 3:317-324.
19. Fiegel J., Fu H., Hanes J. Poly(ether-anhydride) dry powder aerosols for sustained drug delivery in the lungs. J. Controlled Release 2004, 96:411-423.
20. Foged C., Brodin B., Frokjaer S., Sundblad A. Particle size and surface charge affect particle uptake by human dendritic cells in an in vitro model. Int. J. Pharm. 2005, 298:315-322.
21. Fu J., Fiegel J., Krauland E., Hanes J. New polymeric carriers for controlled drug delivery following inhalation or injection. Biomaterials 2002, 23:4425-4433.
22. Garcia-Contreras L., Morcol T., Bell S.J.D., Hickey A.J. Evaluation of novel particles as pulmonary delivery systems for insulin in rats. AAPS Pharm. Sci. 2003, 5:1-11.
23. Göpferich A. Mechanisms of polymer degradation and erosion. Biomaterials 1996, 17:103-114.
24. Govender T., Stolnik S., Garnett M.C., Illum L., Davis S.S. PLGA nanoparticles prepared by nanoprecipitation: drug loading and release studies of a water soluble drug. J. Controlled Release 1999, 57:171-185.
25. Gref R., Minamitake Y., Peracchia M.T., Trubetskoy V., Torchilin V., Langer R. Biodegradable long-circulating polymeric nanosphers. Science 1994, 263:1600-1603.
26. Grenha A., Seijo B., Remuñán-López C. Microencapsulated chitosan nanoparticles for lung protein delivery. Eur. J. Pharm. Sci. 2005, 25:427-437.
27. Harris J.M., Chess R.B. Effect of PEGylation on pharmaceuticals. Nat. Rev. Drug Discovery 2003, 2:214-221.
28. Harris J.M., Zalipsky S. Polyethylene glycol: Chemistry and biological applications. ACS Symp. Ser. 2004, 680:489.
29. He F., Li S.M., Vert M., Zhuo R.X. Enzyme-catalyzed polymerization and degradationof copolymers prepared from epsilon-caprolactone and poly(ethylene glycol). Polymer 2003, 44:5145-5151.
30. Hillery A.M., Lloyd A.W., Swarbrick J. Drug Delivery and Targeting for Pharmaceutical and Pharmaceutical Scientists 2001, Tylor & Francis, London.
31. Jiang G., Woo B.H., Kang F.R., Singh J., DeLuca P.P. Assessment of protein release kinetics, stability and protein polymer interaction of lysozyme encapsulated poly (d, l-lactide-co-glycolide) microspheres. J. Controlled Release 2002, 79:137-145.
32. Kawashima Y., Yamamoto H., Takeuchi H., Fujioka S., Hino T. Pulmonary delivery of insulin with nebulized DL-lactide/glycolide copolymer (PLGA) nanospheres to prolong hypoglycemic effect. J. Controlled Release 1999, 62:279-287.
33. Kim D.H., Martin D.C. Sustained release of dexamethasone from hydrophilic matrices using PLGA nanoparticles for neural drug delivery. Biomaterials 2006, 27:3031-3037.
34. Kumar R., Shakil N.A., Chen M.H., Parmar V.S., Saumelson L.A., Kumar J., Watterson A.C. Chemo-enzymatic synthesis and characterization of novel Functionalized amphiphilic polymers. J. Macromol. Sci.-Pure Appl. Chem. 2002, A39:1137-1149.
35. Leach K.J. Cancer, drug delivery to treat-local and systemic. Encyclopaedia of Contolled Drug Delivery 1999, 123-191. John Wiley & Sons, New York. E. Mathiowitz (Ed.).
36. Learoyd T.P., Burrows J.L., French E., Seville P.C. Sustained delivery of salbutamol and beclometasone from spray-dried double emulsions. J. Microencapsulation 2010, 27:162-170.
37. Leo E., Brina B., Forni F., Angela M. In vitro evaluation of PLA nanoparticles containing a lipophilic drug in water-soluble or insoluble form. Int. J. Pharm. 2004, 278:133-141.
38. Li W.I., Perzl M., Heyder J., Langer R., Brain J.D., Englmeier K.H., et al. Aerodynamics and aerosol particle deaggregation phenomena in model oral-pharyngeal cavities. J. Aerosol Sci. 1996, 27:1269-1286.
39. Li H.Y., Seville P.C., Williamson I.J., Birchall J.C. The use of amino acids to enhance the aerosolisation of spary dried powders for pulmonary gene therapy. J. Gene Med. 2005, 7:1035-1043.
40. Lin W.J., Wang C.L., Chen Y.C. Comparison of two pegylated copolymeric micelles and their potential as drug carriers. Drug Delivery 2005, 12:223-227.
41. Maa Y.F., Nguyen P.A.T., Hsu S.W. Spray-drying of air-liquid interface sensitive recombinant human growth hormone. J. Pharm. Sci. 1998, 87:152-159.
42. Maja K., Marija M., Marjan V., Franc V. Study of the physicochemical parameters affecting the release of diclofenac sodium from lipohilic matrix tablets. Acta Chim. Slov. 2004, 51:409-425.
43. Onoue S., Hashimoto N., Yamada S. Dry powder inhalation systems for pulmonary delivery of therapeutic peptides and proteins. Expert Opin. Ther. Patents 2008, 18:429-442.
44. Puri S., Kallinteri P., Higgins S., Hutcheon G.A., Garnett M.C. Drug incorporation and release of water soluble drugs from noval functionalized poly(glycerol adipate) nanoparticles. J. Controlled Release 2008, 125:59-67.
45. Seville P.C., Learoyd T.P., Li H.Y., Williamson I.J., Birchall J.C. Amino acid-modified spray-dried powders with enhanced aerosolisation properties for pulmonary drug delivery. Powder Tech. 2007, 178:40-50.
46. Ståhl K., Claesson M., Lilliehorn P., Lindén H., Bäckström K. The effect of process variables on the degradation and physical properties of spray dried insulin intended for inhalation. Int. J. Pharm. 2002, 233:227-237.
47. Tawfeek H.M., Khidr S.H., Samy E.M., Ahmed S.M., Shabir A., Mohammed A.R., Hutcheon G.A., Saleem I. Pulmonary delivery of alpha-chymotrypsin via novel polyester microparticles. J. Pharm. Pharmacol. 2010, 62:1294-1295.
48. Tawfeek H., Khidr S., Samy E., Ahmed S., Murphy M., Mohammed A., Shabir A., Hutcheon G., Saleem I. Poly(glycerol adipate-co-ω-pentadecalactone) spary-dried microparticles as sustained release carriers for pulmonary delivery. Pharm. Res. 2011, 28:2086-2097.
49. Thiele L., Rothen-Rutishauser B., Jilek S., Wunderli-Allenspach H., Merkle H.P., Walter E. Evaluation of particle uptake in human blood monocyte-derived cells in vitro. Does phagocytosis activity of dendritic cells measure up with macrophages?. J. Controlled Release 2001, 76:59-71.
50. Thompson C.J., Hansford D., Higgins S., Hutcheon G.A., Rostron C., Munday D.L. Enzymatic synthesis and evaluation of new novel omega-pentadecalactone polymers for the production of biodegradable microspheres. J. Microencapsulation 2006, 23:213-226.
51. Thompson C.J., Hansford D., Higgins S., Rostron C., Hutcheon G., Munday D.L. Evaluation of ibuprofen-loaded microspheres prepared from novel copolyesters. Int. J. Pharm. 2007, 329:53-61.
52. Thompson C.J., Hansford D., Munday D.L., Higgins S., Rostron C., Hutcheon G.A. Synthesis and evaluation of novel polyesteribuprofen conjugates for modified drug release. Drug Dev. Ind. Pharm. 2008, 34:877-884.
53. Tice T.R., Cowsar D.R. Biodegradable contolled-release parenteral systems. Pharm. Tech. 1984, 8:26-34.
54. Uchida T., Yoshida K., Nakada Y., Nagareyan N., Konishi Y., Nakai A., et al. Preparation and characterization of polylactic acid microspheres containing water-soluble anesthetics with small molecular weight. Chem. Pharm. Bull. Tokyo 1997, 45:513-517.
55. Van de Weert M., Hennink W.E., Jiskoot W. Protein instability in poly(lactic-co-glycolic acid) microparticles. Pharm. Res. 2000, 17:1159-1167.
56. Youn Y.S., Kwon M.J., Na D.H., Chae S.Y., Lee S., Lee K.C. Improved intrapulmonary delivery of site-specific PEGylated salmon calcitonin: optimization by PEG size selection. J. Controlled Release 2008, 125:68-75.
57. Zhou Y., Zhuo R.X., Liu Z.L. Synthesis and properties of novel biodegradable triblock copolymers of poly(5-methyl-5-methoxycarbonyl-1,3-dioxan-2-one) and poly(ethylene glycol). Polymer 2004, 45:5459-5463.