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Volumn 329, Issue 1-2, 2007, Pages 53-61

Evaluation of ibuprofen-loaded microspheres prepared from novel copolyesters

Author keywords

Emulsion solvent evaporation; Manufacturing parameters; Microspheres; Polyesters

Indexed keywords

IBUPROFEN; MICROSPHERE; POLYESTER; POLYMER; SHL 509; SHL 510;

EID: 33845575863     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2006.08.019     Document Type: Article
Times cited : (65)

References (56)
  • 1
    • 0028124296 scopus 로고
    • Effect of temperature on mechanisms of drug release and matrix degradation of poly(d, l-lactide) microspheres
    • Aso Y., Yoshioka S., Po L.W., and Terao T. Effect of temperature on mechanisms of drug release and matrix degradation of poly(d, l-lactide) microspheres. J. Contr. Release 31 (1994) 33-39
    • (1994) J. Contr. Release , vol.31 , pp. 33-39
    • Aso, Y.1    Yoshioka, S.2    Po, L.W.3    Terao, T.4
  • 2
    • 0002782942 scopus 로고
    • Microencapsulation
    • Lachman L., Lieberman H.A., and Kanig J.L. (Eds), Lea and Febinger, Philadelphia
    • Bakan J.A. Microencapsulation. In: Lachman L., Lieberman H.A., and Kanig J.L. (Eds). The Theory and Practice of Industrial Pharmacy (1986), Lea and Febinger, Philadelphia 412-429
    • (1986) The Theory and Practice of Industrial Pharmacy , pp. 412-429
    • Bakan, J.A.1
  • 3
    • 0002665262 scopus 로고
    • Microcapsules and microspheres for embolization and chemoembolization
    • Guiot P., and Couvreur P. (Eds), CRC Press, Florida
    • Benoit J.P., and Puisieux F. Microcapsules and microspheres for embolization and chemoembolization. In: Guiot P., and Couvreur P. (Eds). Polymeric Nanoparticles and Microspheres (1986), CRC Press, Florida 143-174
    • (1986) Polymeric Nanoparticles and Microspheres , pp. 143-174
    • Benoit, J.P.1    Puisieux, F.2
  • 4
    • 0037334524 scopus 로고    scopus 로고
    • Preparation of bupivacaine-loaded poly(ε-caprolactone) microspheres by spray drying: drug release studies and biocompatibility
    • Blanco M.D., Bernardo M.V., Sastre R.L., Olmo R., Muñiz E., and Teijón J.M. Preparation of bupivacaine-loaded poly(ε-caprolactone) microspheres by spray drying: drug release studies and biocompatibility. Eur. J. Pharm. Biopharm. 55 (2003) 229-236
    • (2003) Eur. J. Pharm. Biopharm. , vol.55 , pp. 229-236
    • Blanco, M.D.1    Bernardo, M.V.2    Sastre, R.L.3    Olmo, R.4    Muñiz, E.5    Teijón, J.M.6
  • 6
    • 0024445139 scopus 로고
    • Preparation and characterization of microspheres containing the anti-inflammatory agents, indomethacin, ibuprofen, and ketoprofen
    • Bodmeier R., and Chen H. Preparation and characterization of microspheres containing the anti-inflammatory agents, indomethacin, ibuprofen, and ketoprofen. J. Contr. Release 10 (1989) 167-175
    • (1989) J. Contr. Release , vol.10 , pp. 167-175
    • Bodmeier, R.1    Chen, H.2
  • 7
    • 0023904637 scopus 로고
    • Solvent selection in the preparation of poly(dl-lactide) microspheres prepared by the solvent evaporation method
    • Bodmeier R., and McGinity J.W. Solvent selection in the preparation of poly(dl-lactide) microspheres prepared by the solvent evaporation method. Int. J. Pharm. 43 (1988) 179-186
    • (1988) Int. J. Pharm. , vol.43 , pp. 179-186
    • Bodmeier, R.1    McGinity, J.W.2
  • 8
    • 0024553973 scopus 로고
    • The effect of the addition of low molecular weight poly(dl-lactide) on drug release from biodegradable poly(dl-lactide) drug delivery systems
    • Bodmeier R., Oh K.H., and Chen H. The effect of the addition of low molecular weight poly(dl-lactide) on drug release from biodegradable poly(dl-lactide) drug delivery systems. Int. J. Pharm. 51 (1989) 1-8
    • (1989) Int. J. Pharm. , vol.51 , pp. 1-8
    • Bodmeier, R.1    Oh, K.H.2    Chen, H.3
  • 10
    • 0026563624 scopus 로고
    • Use of polylactic acid for the preparation of microparticulate drug delivery systems
    • Conti B., Pavanetto F., and Genta I. Use of polylactic acid for the preparation of microparticulate drug delivery systems. J. Microencapsul. 9 (1992) 153-166
    • (1992) J. Microencapsul. , vol.9 , pp. 153-166
    • Conti, B.1    Pavanetto, F.2    Genta, I.3
  • 11
    • 0000187747 scopus 로고
    • Thermoanalysis of microspheres
    • Dubernet C. Thermoanalysis of microspheres. Thermochim. Acta 248 (1995) 259-269
    • (1995) Thermochim. Acta , vol.248 , pp. 259-269
    • Dubernet, C.1
  • 12
    • 0026059172 scopus 로고
    • Physico-mechanical properties of biodegradable polymers used in medical applications: a comparative study
    • Engelberg I., and Kohn J. Physico-mechanical properties of biodegradable polymers used in medical applications: a comparative study. Biomaterials 12 (1991) 292-304
    • (1991) Biomaterials , vol.12 , pp. 292-304
    • Engelberg, I.1    Kohn, J.2
  • 13
    • 0031740426 scopus 로고    scopus 로고
    • Poly(l-lactic acid) microspheres for pulmonary drug delivery: release kinetics and aerosolization studies
    • El-Baseir M.M., and Kellaway I.W. Poly(l-lactic acid) microspheres for pulmonary drug delivery: release kinetics and aerosolization studies. Int. J. Pharm. 175 (1998) 135-145
    • (1998) Int. J. Pharm. , vol.175 , pp. 135-145
    • El-Baseir, M.M.1    Kellaway, I.W.2
  • 14
    • 0036231029 scopus 로고    scopus 로고
    • PLGA-based microparticles: elucidation of mechanisms and a new, simple mathematical model quantifying drug release
    • Faisant N., Siepmann J., and Benoit J.P. PLGA-based microparticles: elucidation of mechanisms and a new, simple mathematical model quantifying drug release. Eur. J. Pharm. Sci. 15 (2002) 355-366
    • (2002) Eur. J. Pharm. Sci. , vol.15 , pp. 355-366
    • Faisant, N.1    Siepmann, J.2    Benoit, J.P.3
  • 15
    • 3242798076 scopus 로고    scopus 로고
    • Biodegradable ibuprofen-loaded PLGA microspheres for intraarticular administration: effect of Labrafil addition on release in vitro
    • Fernandez-Carballido A., Herrero-Vanrell R., Molina-Martinez I.T., and Pastoriza P. Biodegradable ibuprofen-loaded PLGA microspheres for intraarticular administration: effect of Labrafil addition on release in vitro. Int. J. Pharm. 279 (2004) 33-41
    • (2004) Int. J. Pharm. , vol.279 , pp. 33-41
    • Fernandez-Carballido, A.1    Herrero-Vanrell, R.2    Molina-Martinez, I.T.3    Pastoriza, P.4
  • 16
    • 0011337219 scopus 로고
    • Clinical applications of microspheres in embolization and chemoembolization: comprehensive review and perspectives
    • Rolland A. (Ed), Marcel Dekker, New York
    • Flandroy P.M.J., Grandfils C., and Jerome R. Clinical applications of microspheres in embolization and chemoembolization: comprehensive review and perspectives. In: Rolland A. (Ed). Pharmaceutical Particulate Carriers: Therapeutic Applications (1993), Marcel Dekker, New York 321-366
    • (1993) Pharmaceutical Particulate Carriers: Therapeutic Applications , pp. 321-366
    • Flandroy, P.M.J.1    Grandfils, C.2    Jerome, R.3
  • 17
    • 0034776156 scopus 로고    scopus 로고
    • Characteristics and controlled release of anticancer drug loaded poly(d, l-lactide) microparticles prepared by spray drying technique
    • Fu Y.-J., Mi F.-L., Wong T.-B., and Shyu S.-S. Characteristics and controlled release of anticancer drug loaded poly(d, l-lactide) microparticles prepared by spray drying technique. J. Microencapsul. 18 (2001) 733-747
    • (2001) J. Microencapsul. , vol.18 , pp. 733-747
    • Fu, Y.-J.1    Mi, F.-L.2    Wong, T.-B.3    Shyu, S.-S.4
  • 18
    • 0031751190 scopus 로고    scopus 로고
    • Preparation and in vitro release studies of ibuprofen-loaded films and microspheres made from graft copolymers of poly(l-lactic acid) on acrylic backbones
    • Gallardo A., Eguiburu J.L., Berridi M.J.F., and Roman J.S. Preparation and in vitro release studies of ibuprofen-loaded films and microspheres made from graft copolymers of poly(l-lactic acid) on acrylic backbones. J. Contr. Release 55 (1998) 171-179
    • (1998) J. Contr. Release , vol.55 , pp. 171-179
    • Gallardo, A.1    Eguiburu, J.L.2    Berridi, M.J.F.3    Roman, J.S.4
  • 19
    • 0029129848 scopus 로고
    • Spray-drying as a preparation method of microparticulate drug delivery systems: an overview
    • Giunchedi P., and Conte U. Spray-drying as a preparation method of microparticulate drug delivery systems: an overview. STP Pharm. 5 (1995) 276-290
    • (1995) STP Pharm. , vol.5 , pp. 276-290
    • Giunchedi, P.1    Conte, U.2
  • 20
    • 0029954602 scopus 로고    scopus 로고
    • Investigation of in-vitro release characteristics of NSAID-loaded polylactic acid microspheres
    • Guiziou B., Armstrong D.J., Elliott P.N.C., Ford J.L., and Rostron C. Investigation of in-vitro release characteristics of NSAID-loaded polylactic acid microspheres. J. Microencapsul. 13 (1996) 701-708
    • (1996) J. Microencapsul. , vol.13 , pp. 701-708
    • Guiziou, B.1    Armstrong, D.J.2    Elliott, P.N.C.3    Ford, J.L.4    Rostron, C.5
  • 21
    • 0031765207 scopus 로고    scopus 로고
    • Nifedipine loaded-polymeric microspheres: preparation and physical characteristics
    • Guyot M., and Fawaz F. Nifedipine loaded-polymeric microspheres: preparation and physical characteristics. Int. J. Pharm. 175 (1998) 61-74
    • (1998) Int. J. Pharm. , vol.175 , pp. 61-74
    • Guyot, M.1    Fawaz, F.2
  • 22
    • 0037467194 scopus 로고    scopus 로고
    • Non-degradable microparticles containing a hydrophilic and/or a lipophilic drug: preparation, characterization and drug release modeling
    • Hombreiro-Pérez M., Siepmann J., Zinutti C., Lamprecht A., Ubrich N., Hoffman M., Bodmeier R., and Maincent P. Non-degradable microparticles containing a hydrophilic and/or a lipophilic drug: preparation, characterization and drug release modeling. J. Contr. Release 88 (2003) 413-428
    • (2003) J. Contr. Release , vol.88 , pp. 413-428
    • Hombreiro-Pérez, M.1    Siepmann, J.2    Zinutti, C.3    Lamprecht, A.4    Ubrich, N.5    Hoffman, M.6    Bodmeier, R.7    Maincent, P.8
  • 23
    • 0035850221 scopus 로고    scopus 로고
    • On the importance and mechanisms of burst release in matrix-controlled drug delivery systems
    • Huang X., and Brazel C. On the importance and mechanisms of burst release in matrix-controlled drug delivery systems. J. Contr. Release 73 (2001) 121-136
    • (2001) J. Contr. Release , vol.73 , pp. 121-136
    • Huang, X.1    Brazel, C.2
  • 24
    • 0031845276 scopus 로고    scopus 로고
    • Controlled drug delivery by biodegradable poly(ester) devices: different preparative approaches
    • Jain R., Shah N.H., Malick A.W., and Rhodes C.T. Controlled drug delivery by biodegradable poly(ester) devices: different preparative approaches. Drug Develop. Ind. Pharm. 24 (1999) 703-727
    • (1999) Drug Develop. Ind. Pharm. , vol.24 , pp. 703-727
    • Jain, R.1    Shah, N.H.2    Malick, A.W.3    Rhodes, C.T.4
  • 25
    • 0034580371 scopus 로고    scopus 로고
    • The manufacturing techniques of various drug loaded biodegradable poly(lactide-co-glycolide) (PLGA) devices
    • Jain J.A. The manufacturing techniques of various drug loaded biodegradable poly(lactide-co-glycolide) (PLGA) devices. Biomaterials 21 (2000) 2475-2490
    • (2000) Biomaterials , vol.21 , pp. 2475-2490
    • Jain, J.A.1
  • 26
    • 0037844431 scopus 로고    scopus 로고
    • Extended release lipophilic indomethacin microspheres: formulation factors and mathematical equations fitted drug release rates
    • Karasulu E., Yeşim Karasulu H., Ertan G., Kirilmaz L., and Güneri T. Extended release lipophilic indomethacin microspheres: formulation factors and mathematical equations fitted drug release rates. Eur. J. Pharm. Sci. 19 (2003) 99-104
    • (2003) Eur. J. Pharm. Sci. , vol.19 , pp. 99-104
    • Karasulu, E.1    Yeşim Karasulu, H.2    Ertan, G.3    Kirilmaz, L.4    Güneri, T.5
  • 27
    • 0032188863 scopus 로고    scopus 로고
    • Polymer drugs and polymeric drugs X: slow release of 5-fluorouracil from biodegradable poly(γ-glutamic acid) and its benzyl ester matrices
    • Kishida A., Murakami K., Goto H., Akashi M., Kubita H., and Endo T. Polymer drugs and polymeric drugs X: slow release of 5-fluorouracil from biodegradable poly(γ-glutamic acid) and its benzyl ester matrices. J. Bioact. Compat. Polym. 13 (1998) 270-278
    • (1998) J. Bioact. Compat. Polym. , vol.13 , pp. 270-278
    • Kishida, A.1    Murakami, K.2    Goto, H.3    Akashi, M.4    Kubita, H.5    Endo, T.6
  • 29
    • 84950232819 scopus 로고
    • Polymeric delivery systems for controlled drug release
    • Langer R. Polymeric delivery systems for controlled drug release. Chem. Eng. Commun. 6 (1980) 1-48
    • (1980) Chem. Eng. Commun. , vol.6 , pp. 1-48
    • Langer, R.1
  • 30
    • 0029540462 scopus 로고
    • Biomaterials and biomedical engineering
    • Langer R. Biomaterials and biomedical engineering. Chem. Eng. Sci. 50 (1995) 4109-4121
    • (1995) Chem. Eng. Sci. , vol.50 , pp. 4109-4121
    • Langer, R.1
  • 31
    • 0033951386 scopus 로고    scopus 로고
    • Surface drug removal from ibuprofen-loaded PLA microspheres
    • Leo E., Forni F., and Bernabei M.T. Surface drug removal from ibuprofen-loaded PLA microspheres. Int. J. Pharm. 196 (2000) 1-9
    • (2000) Int. J. Pharm. , vol.196 , pp. 1-9
    • Leo, E.1    Forni, F.2    Bernabei, M.T.3
  • 33
    • 0001021413 scopus 로고
    • Percolation theory-a novel approach to solid dosage form design
    • Leuenberger H., Rohera B.D., and Haas C. Percolation theory-a novel approach to solid dosage form design. Int. J. Pharm. 38 (1987) 109-115
    • (1987) Int. J. Pharm. , vol.38 , pp. 109-115
    • Leuenberger, H.1    Rohera, B.D.2    Haas, C.3
  • 34
    • 0033981065 scopus 로고    scopus 로고
    • Studies on microencapsulation of 5-fluorouracil with poly(ortho ester) polymers
    • Lin Y.-H.E., and Vasavada R.C. Studies on microencapsulation of 5-fluorouracil with poly(ortho ester) polymers. J. Microencapsul. 17 (2000) 1-11
    • (2000) J. Microencapsul. , vol.17 , pp. 1-11
    • Lin, Y.-H.E.1    Vasavada, R.C.2
  • 36
    • 0035914220 scopus 로고    scopus 로고
    • ®) loaded poly(lactic-co-glycolic acid) microspheres prepared by spray drying technique with lipid/cholesterol emulsifiers
    • ®) loaded poly(lactic-co-glycolic acid) microspheres prepared by spray drying technique with lipid/cholesterol emulsifiers. J. Contr. Release 76 (2001) 239-254
    • (2001) J. Contr. Release , vol.76 , pp. 239-254
    • Mu, L.1    Feng, S.S.2
  • 37
    • 0034279006 scopus 로고    scopus 로고
    • Enzymatic synthesis of polyesters from lactones, dicarboxylic acid divinyl esters, and glycols through combination of ring-opening polymerisation and polycondensation
    • Namekawa S., Uyama H., and Kobayashi S. Enzymatic synthesis of polyesters from lactones, dicarboxylic acid divinyl esters, and glycols through combination of ring-opening polymerisation and polycondensation. Biomacromolecules 1 (2000) 335-338
    • (2000) Biomacromolecules , vol.1 , pp. 335-338
    • Namekawa, S.1    Uyama, H.2    Kobayashi, S.3
  • 38
    • 0035907179 scopus 로고    scopus 로고
    • An investigation into the effects of residual water on the glass transition temperature of polylactide microspheres using modulated temperature DSC
    • Passerini N., and Craig D.Q.M. An investigation into the effects of residual water on the glass transition temperature of polylactide microspheres using modulated temperature DSC. J. Contr. Release 73 (2001) 111-115
    • (2001) J. Contr. Release , vol.73 , pp. 111-115
    • Passerini, N.1    Craig, D.Q.M.2
  • 39
    • 0032781442 scopus 로고    scopus 로고
    • Effect of formulation variables on in vitro drug release and micrometric properties of modified release ibuprofen microspheres
    • Perumal D., Dangor C.M., Alcock R.S., Hurbans N., and Moopanar K.R. Effect of formulation variables on in vitro drug release and micrometric properties of modified release ibuprofen microspheres. J. Microencapsul. 16 (1999) 475-487
    • (1999) J. Microencapsul. , vol.16 , pp. 475-487
    • Perumal, D.1    Dangor, C.M.2    Alcock, R.S.3    Hurbans, N.4    Moopanar, K.R.5
  • 40
    • 0035821402 scopus 로고    scopus 로고
    • ® RS 100 by the emulsion solvent diffusion technique
    • ® RS 100 by the emulsion solvent diffusion technique. Int. J. Pharm. 218 (2001) 1-11
    • (2001) Int. J. Pharm. , vol.218 , pp. 1-11
    • Perumal, D.1
  • 41
    • 0035907172 scopus 로고    scopus 로고
    • Brush-like branched biodegradable polyesters, part III. Protein release from microspheres of poly(vinyl alcohol)-graft-poly(d, l-lactic-co-glycolic acid)
    • Pistel K.F., Breitenbach A., Zange-Volland R., and Kissel T. Brush-like branched biodegradable polyesters, part III. Protein release from microspheres of poly(vinyl alcohol)-graft-poly(d, l-lactic-co-glycolic acid). J. Contr. Release 73 (2001) 7-20
    • (2001) J. Contr. Release , vol.73 , pp. 7-20
    • Pistel, K.F.1    Breitenbach, A.2    Zange-Volland, R.3    Kissel, T.4
  • 42
    • 0001922118 scopus 로고
    • Poly(ε-caprolactone) and its copolymers
    • Chasin M., and Langer R. (Eds), Marcel Dekker, New York
    • Pitt C.G. Poly(ε-caprolactone) and its copolymers. In: Chasin M., and Langer R. (Eds). Biodegradable Polymers as Drug Delivery Systems (1990), Marcel Dekker, New York 71-120
    • (1990) Biodegradable Polymers as Drug Delivery Systems , pp. 71-120
    • Pitt, C.G.1
  • 43
    • 0013006703 scopus 로고
    • The need for improved drug delivery in clinical practice
    • Prescott L.F., and Nimmo W.S. (Eds), John Wiley and Sons, Chichester
    • Prescott L.F. The need for improved drug delivery in clinical practice. In: Prescott L.F., and Nimmo W.S. (Eds). Novel Drug Delivery and its Therapeutic Application (1989), John Wiley and Sons, Chichester 1-11
    • (1989) Novel Drug Delivery and its Therapeutic Application , pp. 1-11
    • Prescott, L.F.1
  • 44
    • 25844448637 scopus 로고    scopus 로고
    • Ketoprofen controlled release from composite microcapsules for cell encapsulation: effect on post-transplant acute inflammation
    • Ricci M., Blasi P., Giovagnoli S., Rossi C., Macchiarulo G., Luca G., Basta G., and Calafiore R. Ketoprofen controlled release from composite microcapsules for cell encapsulation: effect on post-transplant acute inflammation. J. Contr. Release 107 (2005) 395-407
    • (2005) J. Contr. Release , vol.107 , pp. 395-407
    • Ricci, M.1    Blasi, P.2    Giovagnoli, S.3    Rossi, C.4    Macchiarulo, G.5    Luca, G.6    Basta, G.7    Calafiore, R.8
  • 45
    • 0023872985 scopus 로고
    • Porous biodegradable microspheres for controlled drug delivery. I. Assessment of processing conditions and solvent removal techniques
    • Sato T., Kanke M., Schroeder H.G., and DeLuca P.P. Porous biodegradable microspheres for controlled drug delivery. I. Assessment of processing conditions and solvent removal techniques. Pharm. Res. 5 (1988) 21-30
    • (1988) Pharm. Res. , vol.5 , pp. 21-30
    • Sato, T.1    Kanke, M.2    Schroeder, H.G.3    DeLuca, P.P.4
  • 47
    • 33744917282 scopus 로고    scopus 로고
    • Enzymatic synthesis and evaluation of new novel ω-pentadecalactone polymers for the production of biodegradable microspheres
    • Thompson C.J., Hansford D., Higgins S., Hutcheon G.A., Rostron C., and Munday D. Enzymatic synthesis and evaluation of new novel ω-pentadecalactone polymers for the production of biodegradable microspheres. J. Microencapsul. 23 (2006) 213-226
    • (2006) J. Microencapsul. , vol.23 , pp. 213-226
    • Thompson, C.J.1    Hansford, D.2    Higgins, S.3    Hutcheon, G.A.4    Rostron, C.5    Munday, D.6
  • 48
    • 0021630153 scopus 로고
    • Biodegradable controlled-release parenteral systems
    • Tice T.R., and Cowsar D.R. Biodegradable controlled-release parenteral systems. Pharm. Technol. 11 (1984) 26-36
    • (1984) Pharm. Technol. , vol.11 , pp. 26-36
    • Tice, T.R.1    Cowsar, D.R.2
  • 49
    • 0342546477 scopus 로고    scopus 로고
    • Diclofenac sodium incorporated PLGA (50:50) microspheres: formulation considerations and in vitro/in vivo evaluation
    • Tunçay M., Calis S., Kas H.S., Ercan M.T., Peksoy I., and Hincal A.A. Diclofenac sodium incorporated PLGA (50:50) microspheres: formulation considerations and in vitro/in vivo evaluation. Int. J. Pharm. 195 (2000) 179-188
    • (2000) Int. J. Pharm. , vol.195 , pp. 179-188
    • Tunçay, M.1    Calis, S.2    Kas, H.S.3    Ercan, M.T.4    Peksoy, I.5    Hincal, A.A.6
  • 50
    • 0033959003 scopus 로고    scopus 로고
    • Mathematical modelling of diffusion-mediated release from bulk degrading matrices
    • Tzafriri A.R. Mathematical modelling of diffusion-mediated release from bulk degrading matrices. J. Contr. Release 63 (2000) 69-79
    • (2000) J. Contr. Release , vol.63 , pp. 69-79
    • Tzafriri, A.R.1
  • 51
    • 0033832635 scopus 로고    scopus 로고
    • Labile conjugation of a hydrophilic drug to PLA oligomers to modify a drug delivery system: cephradin in a PLAGA matrix
    • Ustariz-Peyret C., Coudane J., Vert M., Kaltsatos V., and Boisramené B. Labile conjugation of a hydrophilic drug to PLA oligomers to modify a drug delivery system: cephradin in a PLAGA matrix. J. Microencapsul. 17 (2000) 615-624
    • (2000) J. Microencapsul. , vol.17 , pp. 615-624
    • Ustariz-Peyret, C.1    Coudane, J.2    Vert, M.3    Kaltsatos, V.4    Boisramené, B.5
  • 52
    • 0025694947 scopus 로고
    • Microencapsulation using emulsification/solvent evaporation: an overview of techniques and applications
    • Watts P.J., Davies M.C., and Melia C.D. Microencapsulation using emulsification/solvent evaporation: an overview of techniques and applications. Crit. Rev. Ther. Drug Carr. Sys. 7 (1990) 235-259
    • (1990) Crit. Rev. Ther. Drug Carr. Sys. , vol.7 , pp. 235-259
    • Watts, P.J.1    Davies, M.C.2    Melia, C.D.3
  • 53
    • 0002502026 scopus 로고
    • Biodegradable microspheres for controlled drug delivery
    • Karsa D.R., and Stephenson R.A. (Eds), The Royal Society of Chemistry, Cambridge
    • Whateley T.L. Biodegradable microspheres for controlled drug delivery. In: Karsa D.R., and Stephenson R.A. (Eds). Encapsulation and Controlled Release (1993), The Royal Society of Chemistry, Cambridge 52-65
    • (1993) Encapsulation and Controlled Release , pp. 52-65
    • Whateley, T.L.1
  • 54
    • 0034601882 scopus 로고    scopus 로고
    • Effect of preparation temperature on the characteristics and release profiles of PLGA microspheres containing protein fabricated by double-emulsion solvent extraction/evaporation method
    • Yang Y.Y., Chia H.H., and Chung T.S. Effect of preparation temperature on the characteristics and release profiles of PLGA microspheres containing protein fabricated by double-emulsion solvent extraction/evaporation method. J. Contr. Release 69 (2000) 81-96
    • (2000) J. Contr. Release , vol.69 , pp. 81-96
    • Yang, Y.Y.1    Chia, H.H.2    Chung, T.S.3
  • 55
    • 0032790609 scopus 로고    scopus 로고
    • Protein-loaded poly(ε-caprolactone) microparticles. I. Optimization of the preparation by (water-in-oil)-in water emulsion solvent evaporation
    • Youan B.B., Benoit M.A., Baras B., and Gillard J. Protein-loaded poly(ε-caprolactone) microparticles. I. Optimization of the preparation by (water-in-oil)-in water emulsion solvent evaporation. J. Microencapsul. 16 (1999) 587-599
    • (1999) J. Microencapsul. , vol.16 , pp. 587-599
    • Youan, B.B.1    Benoit, M.A.2    Baras, B.3    Gillard, J.4
  • 56
    • 20144370270 scopus 로고    scopus 로고
    • Preparation, characterization and in vitro release properties of ibuprofen-loaded microspheres based on polylactide, poly(ε-caprolactone) and their copolymers
    • Zhu K.J., Li Y., Jiang H.L., Yasuda H., Ichimaru A., Yamamoto K., Lecomte P., and Jerome R. Preparation, characterization and in vitro release properties of ibuprofen-loaded microspheres based on polylactide, poly(ε-caprolactone) and their copolymers. J. Microencapsul. 22 (2005) 25-36
    • (2005) J. Microencapsul. , vol.22 , pp. 25-36
    • Zhu, K.J.1    Li, Y.2    Jiang, H.L.3    Yasuda, H.4    Ichimaru, A.5    Yamamoto, K.6    Lecomte, P.7    Jerome, R.8


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