Acute metabolic amplification of insulin secretion in mouse islets is mediated by mitochondrial export of metabolites, but not by mitochondrial energy generation

Metabolism: Clinical and Experimental

Volumn 62, Issue 10, 2013, Pages 1375-1386

  Panten, Uwe ^a   Willenborg, Michael ^a   Schumacher, Kirstin ^a   Hamada, Asmaa ^a   Ghaly, Hany ^a   Rustenbeck, Ingo ^a  

^a TECHNICAL UNIVERSITY OF BRAUNSCHWEIG   (Germany)

Author keywords

Acetoacetate; Acetyl CoA; Beta cell; Glucose Ketoisocaproate

Indexed keywords

2 OXOISOCAPROIC ACID; 2 OXOISOVALERIC ACID; ACETOACETIC ACID; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; CITRIC ACID; FUEL; GLIPIZIDE; GLUCOSE; INSULIN; PYRUVIC ACID; ACETOACETIC ACID DERIVATIVE; ALPHA-KETOISOCAPROIC ACID; ALPHA-KETOISOVALERATE; FLAVINE ADENINE NUCLEOTIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; OXOACID; SULFONYLUREA DERIVATIVE;

ANIMAL EXPERIMENT; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENERGY; EXPERIMENTAL DESIGN; FEMALE; FLUORESCENCE; HYPERPOLARIZATION; INSULIN RELEASE; METABOLIC PARAMETERS; METABOLITE; MITOCHONDRION; MOUSE; NONHUMAN; PANCREAS ISLET; PRIORITY JOURNAL; ANIMAL; METABOLISM; PANCREAS ISLET BETA CELL; SECRETION (PROCESS);

ACETOACETATES; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ANIMALS; CITRIC ACID; FEMALE; FLAVIN-ADENINE DINUCLEOTIDE; FLUORESCENCE; GLIPIZIDE; GLUCOSE; INSULIN; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; KETO ACIDS; MICE; MITOCHONDRIA; NADP; PYRUVIC ACID; SULFONYLUREA COMPOUNDS;

EID: 84884530581     PISSN: 00260495     EISSN: 15328600     Source Type: Journal    
DOI: 10.1016/j.metabol.2013.05.006     Document Type: Article

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