메뉴 건너뛰기




Volumn 400, Issue 1, 2006, Pages 81-89

Oxo-4-methylpentanoic acid directs the metabolism of GABA into the Krebs cycle in rat pancreatic islets

Author keywords

amino acid; aminobutyric acid (GABA); Glucose; L leucine; Oxo 4 methylpentanoic acid (OMP); Pancreatic islet

Indexed keywords

AMINO ACIDS; CELLS; CONCENTRATION (PROCESS); ENZYMES; GLUCOSE; INSULIN; METABOLISM;

EID: 33751088531     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20060173     Document Type: Article
Times cited : (11)

References (28)
  • 1
    • 0020037167 scopus 로고
    • Stimulus-secretion coupling of amino acid-induced insulin release VII. The B-cell memory for L-glutamine
    • Somers, G., Carpinelli, A. R., Devis, G., Sener, A. and Malaisse, W. J. (1982) Stimulus-secretion coupling of amino acid-induced insulin release VII. The B-cell memory for L-glutamine. Metab., Clin. Exp 31, 229-237
    • (1982) Metab., Clin. Exp. , vol.31 , pp. 229-237
    • Somers, G.1    Carpinelli, A.R.2    Devis, G.3    Sener, A.4    Malaisse, W.J.5
  • 2
    • 0021320053 scopus 로고
    • Regulation of insulin secretion by energy metabolism in pancreatic B-ceil mitoctiondria. Studies with a non-metabolizable analogue
    • Panten, U., Zielmann, S., Lange. J., Zünkler, B.-J. and Lenzen, S. (1984) Regulation of insulin secretion by energy metabolism in pancreatic B-ceil mitoctiondria. Studies with a non-metabolizable analogue. Biochem. J. 219, 189-196
    • (1984) Biochem. J. , vol.219 , pp. 189-196
    • Panten, U.1    Zielmann, S.2    Lange, J.3    Zünkler, B.-J.4    Lenzen, S.5
  • 3
    • 0019133275 scopus 로고
    • L-leucine and a nonmetabolized analogue activate pancreatic islet glutamate dehydrogenase
    • Sener, A. and Malaisse, W. J. (1980) L-leucine and a nonmetabolized analogue activate pancreatic islet glutamate dehydrogenase. Nature 288, 187-189
    • (1980) Nature , vol.288 , pp. 187-189
    • Sener, A.1    Malaisse, W.J.2
  • 5
    • 0019433688 scopus 로고
    • Insulin release: Reconciliation of the receptor and metabolic hypothesis. Nutrient receptors in islet cells
    • Malaisse, W. J., Sener, A. and Malaisse-Lagae, F. (1981) Insulin release: reconciliation of the receptor and metabolic hypothesis. Nutrient receptors in islet cells. Mol. Cell. Biochem. 37, 157-165
    • (1981) Mol. Cell. Biochem. , vol.37 , pp. 157-165
    • Malaisse, W.J.1    Sener, A.2    Malaisse-Lagae, F.3
  • 8
    • 0022347742 scopus 로고
    • Transamination of neutral amino acids and 2-keto acids in pancreatic B-cell mitochondria
    • Lenzen, S., Schmidt, W. and Panten, U. (1985) Transamination of neutral amino acids and 2-keto acids in pancreatic B-cell mitochondria. J. Biol. Chem. 260, 12629-12634
    • (1985) J. Biol. Chem. , vol.260 , pp. 12629-12634
    • Lenzen, S.1    Schmidt, W.2    Panten, U.3
  • 12
    • 0023256869 scopus 로고
    • Immunoreactive GABA transaminase within the pancreatic islet is localized in mitochondria of the B-cell
    • Garry, D. J., Coulter, H. D., McIntee, T. J., Wu, J.-Y. and Sorenson, R. L. (1987) Immunoreactive GABA transaminase within the pancreatic islet is localized in mitochondria of the B-cell. J. Histochem. Cytochem. 35, 831-836
    • (1987) J. Histochem. Cytochem. , vol.35 , pp. 831-836
    • Garry, D.J.1    Coulter, H.D.2    McIntee, T.J.3    Wu, J.-Y.4    Sorenson, R.L.5
  • 14
    • 0037106619 scopus 로고    scopus 로고
    • Novel homodimeric rat γ-hydroxybutyrate synthases that associate with the Golgi apparatus define a distinct subclass of aldo-keto reductase 7 family proteins
    • Kelly, V. P., Sherratt, P. J., Crouch, D. H. and Hayes, J. D. (2002) Novel homodimeric rat γ-hydroxybutyrate synthases that associate with the Golgi apparatus define a distinct subclass of aldo-keto reductase 7 family proteins. Biochem. J. 366, 847-861
    • (2002) Biochem. J. , vol.366 , pp. 847-861
    • Kelly, V.P.1    Sherratt, P.J.2    Crouch, D.H.3    Hayes, J.D.4
  • 15
    • 0015297746 scopus 로고
    • The pentose cycle and insulin release in mouse pancreatic islets
    • Asbcroft, S. J. H., Weerasinghe, C. C., Bassett, J. M. and Randle, P. J. (1972) The pentose cycle and insulin release in mouse pancreatic islets. Biochem. J. 126, 525-532
    • (1972) Biochem. J. , vol.126 , pp. 525-532
    • Asbcroft, S.J.H.1    Weerasinghe, C.C.2    Bassett, J.M.3    Randle, P.J.4
  • 16
    • 84911562381 scopus 로고
    • Amino acid analysis and enzymatic sequence determination of peptides by an improved o-phtalaldialdehyde precolumn labeling procedure
    • Jones, B. N., Paabo, S. and Stein, S. (1981) Amino acid analysis and enzymatic sequence determination of peptides by an improved o-phtalaldialdehyde precolumn labeling procedure. J. Liq. Chromatogr. 4, 565-586
    • (1981) J. Liq. Chromatogr. , vol.4 , pp. 565-586
    • Jones, B.N.1    Paabo, S.2    Stein, S.3
  • 18
    • 0033789943 scopus 로고    scopus 로고
    • Oscillations in oxygen tension and insulin release of individual pancreatic ob/ob mouse islets
    • Ortsäter, H., Liss, P., Lund, P. E., Åkerman, K. E. O. and Bergsten, P. (2000) Oscillations in oxygen tension and insulin release of individual pancreatic ob/ob mouse islets. Diabetologia 43, 1313-1318
    • (2000) Diabetologia , vol.43 , pp. 1313-1318
    • Ortsäter, H.1    Liss, P.2    Lund, P.E.3    Åkerman, K.E.O.4    Bergsten, P.5
  • 20
    • 0018415451 scopus 로고
    • Inhibition of brain glutamate decarboxylase by 2-keto-4-pentenoic acid, a metabolite of allylglycine
    • Reingold, D. F. and Orlowski, M. (1979) Inhibition of brain glutamate decarboxylase by 2-keto-4-pentenoic acid, a metabolite of allylglycine. J. Neurochem. 32, 907-913
    • (1979) J. Neurochem. , vol.32 , pp. 907-913
    • Reingold, D.F.1    Orlowski, M.2
  • 22
    • 0019858605 scopus 로고
    • The stimulus-secretion coupling of amino acid-induced insulin release: Metabolic interaction of L-glutamine and 2-ketoisocaproate in pancreatic islets
    • Malaisse, W. J., Sener, A., Malaisse-Lagae, F., Hutton, J. C. and and Christophe, J. (1981) The stimulus-secretion coupling of amino acid-induced insulin release: metabolic interaction of L-glutamine and 2-ketoisocaproate in pancreatic islets. Biochim. Biophys. Acta 677, 39-49
    • (1981) Biochim. Biophys. Acta , vol.677 , pp. 39-49
    • Malaisse, W.J.1    Sener, A.2    Malaisse-Lagae, F.3    Hutton, J.C.4    Christophe, J.5
  • 23
    • 0028106823 scopus 로고
    • Regulation of the glutamate dehydrogenase activity in rat islets of Langerhans and its consequence on insulin release
    • Bryla, B., Michalik, M., Nelson, J. and Erecinska, M. (1994) Regulation of the glutamate dehydrogenase activity in rat islets of Langerhans and its consequence on insulin release. Metab. Clin. Endocrinol. 43, 1187-1195
    • (1994) Metab. Clin. Endocrinol. , vol.43 , pp. 1187-1195
    • Bryla, B.1    Michalik, M.2    Nelson, J.3    Erecinska, M.4
  • 24
    • 0031438061 scopus 로고    scopus 로고
    • Nutrient regulation of γ-aminobutyric acid release from islet β cells
    • Smismans, A., Schuit, F. and Pipeleers, D. (1997) Nutrient regulation of γ-aminobutyric acid release from islet β cells. Diabetologia 40, 1411-1415
    • (1997) Diabetologia , vol.40 , pp. 1411-1415
    • Smismans, A.1    Schuit, F.2    Pipeleers, D.3
  • 25
    • 0020319986 scopus 로고
    • Signal function of metabolism of neutral amino acids and 2-keto acids for initiation of insulin secretion
    • Lenzen, S., Formanek, H. and Panten, U. (1982) Signal function of metabolism of neutral amino acids and 2-keto acids for initiation of insulin secretion. J. Biol.Chem. 257, 6631-6633
    • (1982) J. Biol.Chem. , vol.257 , pp. 6631-6633
    • Lenzen, S.1    Formanek, H.2    Panten, U.3
  • 26
    • 0016302539 scopus 로고    scopus 로고
    • Inhibition by the branched-chain 2-oxo acids of the 2-oxoglutarate dehydrogenase complex in developing rat and human brain
    • (974)
    • Patel, M. (974) Inhibition by the branched-chain 2-oxo acids of the 2-oxoglutarate dehydrogenase complex in developing rat and human brain. Biocbem. J. 144, 91-97
    • Biocbem. J. , vol.144 , pp. 91-97
    • Patel, M.1
  • 28
    • 0032806183 scopus 로고    scopus 로고
    • Glucose regulation of glutaminolysis and its role in insulin secretion
    • Gao, Z. Y., Li, G., Najafi, H., Wolf, B. A. and Matschinsky, F. M. (1999) Glucose regulation of glutaminolysis and its role in insulin secretion. Diabetes 47, 1535-1542
    • (1999) Diabetes , vol.47 , pp. 1535-1542
    • Gao, Z.Y.1    Li, G.2    Najafi, H.3    Wolf, B.A.4    Matschinsky, F.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.