메뉴 건너뛰기




Volumn 53, Issue 1, 2011, Pages 160-170

Lupeol targets liver tumor-initiating cells through phosphatase and tensin homolog modulation

Author keywords

[No Author keywords available]

Indexed keywords

BREAST CANCER RESISTANCE PROTEIN; CD133 ANTIGEN; CISPLATIN; DOXORUBICIN; LENTIVIRUS VECTOR; LUPEOL; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B;

EID: 78751552761     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.24000     Document Type: Article
Times cited : (93)

References (38)
  • 2
    • 7044239399 scopus 로고    scopus 로고
    • Hepatocellular carcinoma: current management and future trends
    • Carr BI. Hepatocellular carcinoma: current management and future trends. Gastroenterology 2004; 127: 218-224.
    • (2004) Gastroenterology , vol.127 , pp. 218-224
    • Carr, B.I.1
  • 3
    • 33847702042 scopus 로고    scopus 로고
    • Liver resection and transplantation in the management of hepatocellular carcinoma: a review
    • Kassahun WT, Fangmann J, Harm J, Hauss J, Bartels M. Liver resection and transplantation in the management of hepatocellular carcinoma: a review. Ex Clin Transplant 2006; 4: 549-558.
    • (2006) Ex Clin Transplant , vol.4 , pp. 549-558
    • Kassahun, W.T.1    Fangmann, J.2    Harm, J.3    Hauss, J.4    Bartels, M.5
  • 4
    • 0034793993 scopus 로고    scopus 로고
    • Nonsurgical treatment of hepatocellular carcinoma
    • Aguayo A, Patt YZ. Nonsurgical treatment of hepatocellular carcinoma. Semin Oncol 2001; 28: 503-513.
    • (2001) Semin Oncol , vol.28 , pp. 503-513
    • Aguayo, A.1    Patt, Y.Z.2
  • 5
    • 0036775308 scopus 로고    scopus 로고
    • Radiofrequency ablation of liver tumors: influence of technique and tumor size
    • Kuvshinoff BW, Ota DM. Radiofrequency ablation of liver tumors: influence of technique and tumor size. Surgery 2002; 132: 605-611.
    • (2002) Surgery , vol.132 , pp. 605-611
    • Kuvshinoff, B.W.1    Ota, D.M.2
  • 6
    • 0037308133 scopus 로고    scopus 로고
    • Systematic review of randomized trials for unresectable hepatocellular carcinoma: chemoembolization improves survival
    • Llovet JM, Bruix J. Systematic review of randomized trials for unresectable hepatocellular carcinoma: chemoembolization improves survival. HEPATOLOGY 2003; 37: 429-442.
    • (2003) HEPATOLOGY , vol.37 , pp. 429-442
    • Llovet, J.M.1    Bruix, J.2
  • 7
    • 0037079003 scopus 로고    scopus 로고
    • Rules for making human tumor cells
    • Hahn WC, Weinberg RA. Rules for making human tumor cells. N Engl J Med 2002; 347: 1593-1603.
    • (2002) N Engl J Med , vol.347 , pp. 1593-1603
    • Hahn, W.C.1    Weinberg, R.A.2
  • 8
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000; 100: 57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 9
    • 33644826473 scopus 로고    scopus 로고
    • Roots and stems: stem cells in cancer
    • Polyak K, Hahn CW. Roots and stems: stem cells in cancer. Nat Med 2005; 11: 296-300.
    • (2005) Nat Med , vol.11 , pp. 296-300
    • Polyak, K.1    Hahn, C.W.2
  • 11
    • 47849087204 scopus 로고    scopus 로고
    • Stem cells and cancer in the liver
    • Taniguchi H, Chiba T. Stem cells and cancer in the liver. Dis Markers 2008; 24: 223-229.
    • (2008) Dis Markers , vol.24 , pp. 223-229
    • Taniguchi, H.1    Chiba, T.2
  • 13
    • 33846100356 scopus 로고    scopus 로고
    • A human colon cancer cell capable of initiating tumor growth in immunodeficient mice
    • O'Brien CA, Pollett A, Gallinger S, Dick JE. A human colon cancer cell capable of initiating tumor growth in immunodeficient mice. Nature 2007; 445: 106-110.
    • (2007) Nature , vol.445 , pp. 106-110
    • O'Brien, C.A.1    Pollett, A.2    Gallinger, S.3    Dick, J.E.4
  • 15
    • 28244472369 scopus 로고    scopus 로고
    • Prospective identification of tumorigenic prostate cancer stem cells
    • Collin AT, Berry PA, Hyde C, Stower MJ, Maitland NJ. Prospective identification of tumorigenic prostate cancer stem cells. Cancer Res 2005; 65: 10946-10951.
    • (2005) Cancer Res , vol.65 , pp. 10946-10951
    • Collin, A.T.1    Berry, P.A.2    Hyde, C.3    Stower, M.J.4    Maitland, N.J.5
  • 16
    • 27144557960 scopus 로고    scopus 로고
    • A tumorigenic subpopulation with stem cell properties in melanomas
    • Fang D, Nguyen TK, Leishear K, Finko R, Kulp AN, Hotz S, et al. A tumorigenic subpopulation with stem cell properties in melanomas. Cancer Res 2005; 65: 9328-9337.
    • (2005) Cancer Res , vol.65 , pp. 9328-9337
    • Fang, D.1    Nguyen, T.K.2    Leishear, K.3    Finko, R.4    Kulp, A.N.5    Hotz, S.6
  • 17
    • 34548455927 scopus 로고    scopus 로고
    • Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer
    • Hermann PC, Huber SL, Herrler T, Aicher A, Ellwart JW, Guba M, et al. Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer. Cell Stem Cell 2007; 1: 313-323.
    • (2007) Cell Stem Cell , vol.1 , pp. 313-323
    • Hermann, P.C.1    Huber, S.L.2    Herrler, T.3    Aicher, A.4    Ellwart, J.W.5    Guba, M.6
  • 18
    • 33846512398 scopus 로고    scopus 로고
    • Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma
    • Prince ME, Sivanandan R, Kaczorowski A, Wolf GT, Kaplan MJ, Dalerba P, et al. Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma. Proc Natl Acad Sci U S A 2007; 104: 973-978.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 973-978
    • Prince, M.E.1    Sivanandan, R.2    Kaczorowski, A.3    Wolf, G.T.4    Kaplan, M.J.5    Dalerba, P.6
  • 19
    • 34249980343 scopus 로고    scopus 로고
    • Identification and characterization of tumorigenic liver cancer stem/progenitor cells
    • Ma S, Chan KW, Hu L, Lee TK, Wo JY, Ng IO, et al. Identification and characterization of tumorigenic liver cancer stem/progenitor cells. Gastroenterology 2007; 132: 2542-2556.
    • (2007) Gastroenterology , vol.132 , pp. 2542-2556
    • Ma, S.1    Chan, K.W.2    Hu, L.3    Lee, T.K.4    Wo, J.Y.5    Ng, I.O.6
  • 20
    • 38549139140 scopus 로고    scopus 로고
    • Significance of CD90+ cancer stem cells in human liver cancer
    • Yang ZF, Ho DW, Ng MN, Lau CK, Yu WC, Ngai P, et al. Significance of CD90+ cancer stem cells in human liver cancer. Cancer Cell 2008; 13: 153-166.
    • (2008) Cancer Cell , vol.13 , pp. 153-166
    • Yang, Z.F.1    Ho, D.W.2    Ng, M.N.3    Lau, C.K.4    Yu, W.C.5    Ngai, P.6
  • 21
    • 36348991571 scopus 로고    scopus 로고
    • Activation of hepatic stem cell marker EpCAM by Wnt-beta-catenin signaling in hepatocellular carcinoma
    • Yamashita T, Budhu A, Forgues M, Wang XW. Activation of hepatic stem cell marker EpCAM by Wnt-beta-catenin signaling in hepatocellular carcinoma. Cancer Res 2007; 67: 10831-10839.
    • (2007) Cancer Res , vol.67 , pp. 10831-10839
    • Yamashita, T.1    Budhu, A.2    Forgues, M.3    Wang, X.W.4
  • 22
    • 58149231321 scopus 로고    scopus 로고
    • JPHC Study Group. Vegetable, fruit and antioxidant nutrient consumption and subsequent risk of hepatocellular carcinoma: a prospective cohort study in Japan
    • Kurahashi N, Inoue M, Iwasaki M, Tanaka Y, Mizokami M, Tsugane S; JPHC Study Group. Vegetable, fruit and antioxidant nutrient consumption and subsequent risk of hepatocellular carcinoma: a prospective cohort study in Japan. Br J Cancer 2009; 100: 181-184.
    • (2009) Br J Cancer , vol.100 , pp. 181-184
    • Kurahashi, N.1    Inoue, M.2    Iwasaki, M.3    Tanaka, Y.4    Mizokami, M.5    Tsugane, S.6
  • 23
    • 0031008177 scopus 로고    scopus 로고
    • Attributable risks for hepatocellular carcinoma in northern Italy
    • Braga C, La Vecchia C, Negri E, Franceschi S. Attributable risks for hepatocellular carcinoma in northern Italy. Eur J Cancer 1997; 33: 629-634.
    • (1997) Eur J Cancer , vol.33 , pp. 629-634
    • Braga, C.1    La Vecchia, C.2    Negri, E.3    Franceschi, S.4
  • 24
    • 34548763142 scopus 로고    scopus 로고
    • Lupeol suppresses cisplatin induced NFκB activation in HNSCC cells and inhibits local invasion and nodal metastasis in orthotopic nude mouse model of tongue squamous cell carcinoma
    • Lee TK, Poon RT, Guan XY, Ma S, Guan XY, Myers JN, et al. Lupeol suppresses cisplatin induced NFκB activation in HNSCC cells and inhibits local invasion and nodal metastasis in orthotopic nude mouse model of tongue squamous cell carcinoma. Cancer Res 2007; 67: 8800-8809.
    • (2007) Cancer Res , vol.67 , pp. 8800-8809
    • Lee, T.K.1    Poon, R.T.2    Guan, X.Y.3    Ma, S.4    Guan, X.Y.5    Myers, J.N.6
  • 25
    • 0033960043 scopus 로고    scopus 로고
    • A long-term hepatitis B viremia model generated by transplanting nontumorigenic immortalized human hepatocytes in Rag-2-deficient mice
    • Brown JJ, Parashar B, Moshage H, Tanaka KE, Engelhardt D, Rabbani E, et al. A long-term hepatitis B viremia model generated by transplanting nontumorigenic immortalized human hepatocytes in Rag-2-deficient mice. HEPATOLOGY 2000; 31: 173-181.
    • (2000) HEPATOLOGY , vol.31 , pp. 173-181
    • Brown, J.J.1    Parashar, B.2    Moshage, H.3    Tanaka, K.E.4    Engelhardt, D.5    Rabbani, E.6
  • 26
    • 3142676732 scopus 로고    scopus 로고
    • Lupeol modulates NFκB and PI3/Akt pathways and inhibits skin cancer in CD-1 mice
    • Saleem M, Afaq F, Adhami VM, Mukhtar H. Lupeol modulates NFκB and PI3/Akt pathways and inhibits skin cancer in CD-1 mice. Oncogene 2004; 23: 5203-5214.
    • (2004) Oncogene , vol.23 , pp. 5203-5214
    • Saleem, M.1    Afaq, F.2    Adhami, V.M.3    Mukhtar, H.4
  • 27
    • 18944407603 scopus 로고    scopus 로고
    • Mammary stem cells, self-renewal pathways, and carcinogenesis
    • Liu S, Dontu G, Wicha MS. Mammary stem cells, self-renewal pathways, and carcinogenesis. Breast Cancer Res 2005; 7: 86-95.
    • (2005) Breast Cancer Res , vol.7 , pp. 86-95
    • Liu, S.1    Dontu, G.2    Wicha, M.S.3
  • 28
    • 40749150740 scopus 로고    scopus 로고
    • CD133+ HCC cancer stem cells confer chemoresistance by preferential expression of the Akt/PKB survival pathway
    • Ma S, Lee TK, Zheng BJ, Chan KW, Guan XY. CD133+ HCC cancer stem cells confer chemoresistance by preferential expression of the Akt/PKB survival pathway. Oncogene 2008; 27: 1749-1758.
    • (2008) Oncogene , vol.27 , pp. 1749-1758
    • Ma, S.1    Lee, T.K.2    Zheng, B.J.3    Chan, K.W.4    Guan, X.Y.5
  • 29
    • 62549136153 scopus 로고    scopus 로고
    • Expansion of CD133-expressing liver cancer stem cells in liver-specific phosphatase and tensin homolog deleted on chromosome 10-deleted mice
    • Rountree CB, Ding W, He L, Stiles B. Expansion of CD133-expressing liver cancer stem cells in liver-specific phosphatase and tensin homolog deleted on chromosome 10-deleted mice. Stem Cells 2009; 27: 290-299.
    • (2009) Stem Cells , vol.27 , pp. 290-299
    • Rountree, C.B.1    Ding, W.2    He, L.3    Stiles, B.4
  • 30
    • 60849117508 scopus 로고    scopus 로고
    • PTEN/PI3K/Akt pathway regulates the side population phenotype and ABCG2 activitiy in glioma tumor stem-like cells
    • Bleau AM, Hambardzumyan D, Ozawa T, Fomchenko EI, Huse JT, Brennan CW, et al. PTEN/PI3K/Akt pathway regulates the side population phenotype and ABCG2 activitiy in glioma tumor stem-like cells. Cell Stem Cell 2009; 4: 226-235.
    • (2009) Cell Stem Cell , vol.4 , pp. 226-235
    • Bleau, A.M.1    Hambardzumyan, D.2    Ozawa, T.3    Fomchenko, E.I.4    Huse, J.T.5    Brennan, C.W.6
  • 31
    • 26444503696 scopus 로고    scopus 로고
    • Akt phosphorylation associates with LOH of PTEN and leads to chemoresistance for gastric cancer
    • Oki E, Baba H, Tokunaga E, Nakamura T, Ueda N, Futatsugi M, et al. Akt phosphorylation associates with LOH of PTEN and leads to chemoresistance for gastric cancer. Int J Cancer 2005; 117: 376-380.
    • (2005) Int J Cancer , vol.117 , pp. 376-380
    • Oki, E.1    Baba, H.2    Tokunaga, E.3    Nakamura, T.4    Ueda, N.5    Futatsugi, M.6
  • 32
    • 53749088741 scopus 로고    scopus 로고
    • Identification of side population cells in human hepatocellular carcinoma cell lines with stepwise metastatic potentials
    • Shi GM, Xu Y, Fan J, Zhou J, Yang XR, Qiu SJ, et al. Identification of side population cells in human hepatocellular carcinoma cell lines with stepwise metastatic potentials. J Cancer Res Clin Oncol 2008; 134: 1155-1163.
    • (2008) J Cancer Res Clin Oncol , vol.134 , pp. 1155-1163
    • Shi, G.M.1    Xu, Y.2    Fan, J.3    Zhou, J.4    Yang, X.R.5    Qiu, S.J.6
  • 33
    • 16844368698 scopus 로고    scopus 로고
    • Tumour stem cells and drug resistance
    • Dean M, Fojo T, Bates S. Tumour stem cells and drug resistance. Nat Rev Cancer 2005; 5: 275-284.
    • (2005) Nat Rev Cancer , vol.5 , pp. 275-284
    • Dean, M.1    Fojo, T.2    Bates, S.3
  • 36
    • 0042355204 scopus 로고    scopus 로고
    • Regulation of constitutive expression of mouse PTEN by the 5'-untranslated region
    • Han B, Dong Z, Liu Y, Chen Q, Hashimoto K, Zhang J-T. Regulation of constitutive expression of mouse PTEN by the 5'-untranslated region. Oncogene 2003; 22: 5325-5337.
    • (2003) Oncogene , vol.22 , pp. 5325-5337
    • Han, B.1    Dong, Z.2    Liu, Y.3    Chen, Q.4    Hashimoto, K.5    Zhang, J.-T.6
  • 37
    • 57349094741 scopus 로고    scopus 로고
    • Analysis of ABCG2 express and side population identifies intrinsic drug efflux in the HCC cell line MHCC-97L and its modulation by Akt signalling
    • Hu C, Li H, Zhu Z, Yin S, Hao X, Yao M, et al. Analysis of ABCG2 express and side population identifies intrinsic drug efflux in the HCC cell line MHCC-97L and its modulation by Akt signalling. Carcinogenesis 2008; 12: 2289-2297.
    • (2008) Carcinogenesis , vol.12 , pp. 2289-2297
    • Hu, C.1    Li, H.2    Zhu, Z.3    Yin, S.4    Hao, X.5    Yao, M.6
  • 38
    • 70349479538 scopus 로고    scopus 로고
    • Highly tumorigenic lung cancer CD133+ cells display stem-like features and are spared by cisplatin treatment
    • Bertolini G, Roz L, Perego P, Tortoreto M, Fontanella E, Gatti L, et al. Highly tumorigenic lung cancer CD133+ cells display stem-like features and are spared by cisplatin treatment. Proc Natl Acad Sci U S A 2009; 106: 16281-16286.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 16281-16286
    • Bertolini, G.1    Roz, L.2    Perego, P.3    Tortoreto, M.4    Fontanella, E.5    Gatti, L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.