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Volumn 368, Issue 1629, 2013, Pages

Epithelial polarity and spindle orientation: Intersecting pathways

Author keywords

Epithelial polarity; Mitosis; Spindle orientation

Indexed keywords

CELL ORGANELLE; CHROMOSOME; STEM;

EID: 84884491658     PISSN: 09628436     EISSN: 14712970     Source Type: Journal    
DOI: 10.1098/rstb.2013.0291     Document Type: Review
Times cited : (40)

References (91)
  • 1
    • 64049088018 scopus 로고    scopus 로고
    • Spindle orientation during asymmetric cell division
    • (doi:10.1038/ncb0409-365)
    • Siller KH, Doe CQ. 2009 Spindle orientation during asymmetric cell division. Nat. Cell Biol. 11, 365-374. (doi:10.1038/ncb0409-365)
    • (2009) Nat. Cell Biol. , vol.11 , pp. 365-374
    • Siller, K.H.1    Doe, C.Q.2
  • 2
    • 79960207659 scopus 로고    scopus 로고
    • Mitotic spindle orientation in asymmetric and symmetric cell divisions during animal development
    • (doi:10.1016/j.devcel.2011.06.012)
    • Morin X, Bellaïche Y. 2011 Mitotic spindle orientation in asymmetric and symmetric cell divisions during animal development. Dev. Cell 21, 102-119. (doi:10.1016/j.devcel.2011.06.012)
    • (2011) Dev. Cell , vol.21 , pp. 102-119
    • Morin, X.1    Bellaïche, Y.2
  • 3
    • 0034681261 scopus 로고    scopus 로고
    • Analysis of partner of inscuteable, a novel player of Drosophila asymmetric divisions, reveals two distinct steps in inscuteable apical localization
    • (doi:10.1016/S0092-8674(00)80676-5)
    • Yu F, Morin X, Cai Y, Yang X, Chia W. 2000 Analysis of partner of inscuteable, a novel player of Drosophila asymmetric divisions, reveals two distinct steps in inscuteable apical localization. Cell 100, 399-409. (doi:10.1016/S0092-8674(00)80676-5)
    • (2000) Cell , vol.100 , pp. 399-409
    • Yu, F.1    Morin, X.2    Cai, Y.3    Yang, X.4    Chia, W.5
  • 4
    • 0035205087 scopus 로고    scopus 로고
    • A mammalian Partner of inscuteable binds NuMA and regulates mitotic spindle organization
    • (doi:10.1038/ncb1201-1069)
    • Du Q, Stukenberg PT, Macara IG. 2001 A mammalian Partner of inscuteable binds NuMA and regulates mitotic spindle organization. Nat. Cell Biol. 3, 1069-1075. (doi:10.1038/ncb1201-1069)
    • (2001) Nat. Cell Biol. , vol.3 , pp. 1069-1075
    • Du, Q.1    Stukenberg, P.T.2    Macara, I.G.3
  • 5
    • 0041969719 scopus 로고    scopus 로고
    • Subcellular localization of LGN during mitosis: Evidence for its cortical localization in mitotic cell culture systems and its requirement for normal cell cycle progression
    • (doi:10.1091/mbc.E03-04-0212)
    • Kaushik R, Yu F, Chia W, Yang X, Bahri S. 2003 Subcellular localization of LGN during mitosis: evidence for its cortical localization in mitotic cell culture systems and its requirement for normal cell cycle progression. Mol. Biol. Cell 14, 3144-3155. (doi:10.1091/mbc.E03-04-0212)
    • (2003) Mol. Biol. Cell , vol.14 , pp. 3144-3155
    • Kaushik, R.1    Yu, F.2    Chia, W.3    Yang, X.4    Bahri, S.5
  • 6
    • 0037948857 scopus 로고    scopus 로고
    • A complex of LIN-5 and GPR proteins regulates G protein signaling and spindle function in C. elegans
    • (doi:10. 1101/gad.1081203)
    • Srinivasan DG, Fisk RM, Xu H, van den Heuvel S. 2003 A complex of LIN-5 and GPR proteins regulates G protein signaling and spindle function in C. elegans. Genes Dev. 17, 1225-1239. (doi:10. 1101/gad.1081203)
    • (2003) Genes Dev. , vol.17 , pp. 1225-1239
    • Srinivasan, D.G.1    Fisk, R.M.2    Xu, H.3    van den Heuvel, S.4
  • 7
    • 0037665297 scopus 로고    scopus 로고
    • Asymmetrically distributed C. elegans homologs of AGS3/PINS control spindle position in the early embryo
    • (doi:10.1016/S0960-9822(03)00371-3)
    • Gotta M, Dong Y, Peterson YK, Lanier SM, Ahringer J. 2003 Asymmetrically distributed C. elegans homologs of AGS3/PINS control spindle position in the early embryo. Curr. Biol. 13, 1029-1037. (doi:10.1016/S0960-9822(03)00371-3)
    • (2003) Curr. Biol. , vol.13 , pp. 1029-1037
    • Gotta, M.1    Dong, Y.2    Peterson, Y.K.3    Lanier, S.M.4    Ahringer, J.5
  • 8
    • 0038046388 scopus 로고    scopus 로고
    • Translation of polarity cues into asymmetric spindle positioning in Caenorhabditis elegans embryos
    • (doi:10.1126/science.1084146)
    • Colombo K, Grill SW, Kimple RJ, Willard FS, Siderovski DP, Gönczy P. 2003 Translation of polarity cues into asymmetric spindle positioning in Caenorhabditis elegans embryos. Science 300, 1957-1961. (doi:10.1126/science.1084146)
    • (2003) Science , vol.300 , pp. 1957-1961
    • Colombo, K.1    Grill, S.W.2    Kimple, R.J.3    Willard, F.S.4    Siderovski, D.P.5    Gönczy, P.6
  • 9
    • 33744794908 scopus 로고    scopus 로고
    • Drosophila Pins-binding protein Mud regulates spindle-polarity coupling and centrosome organization
    • (doi:10.1038/ncb1409)
    • Izumi Y, Ohta N, Hisata K, Raabe T, Matsuzaki F. 2006 Drosophila Pins-binding protein Mud regulates spindle-polarity coupling and centrosome organization. Nat. Cell Biol. 8, 586-593. (doi:10.1038/ncb1409)
    • (2006) Nat. Cell Biol. , vol.8 , pp. 586-593
    • Izumi, Y.1    Ohta, N.2    Hisata, K.3    Raabe, T.4    Matsuzaki, F.5
  • 10
    • 33744811175 scopus 로고    scopus 로고
    • The NuMArelated Mud protein binds Pins and regulates spindle orientation in Drosophila neuroblasts
    • (doi:10.1038/ncb1412)
    • Siller KH, Cabernard C, Doe CQ. 2006 The NuMArelated Mud protein binds Pins and regulates spindle orientation in Drosophila neuroblasts. Nat. Cell Biol. 8, 594-600. (doi:10.1038/ncb1412)
    • (2006) Nat. Cell Biol. , vol.8 , pp. 594-600
    • Siller, K.H.1    Cabernard, C.2    Doe, C.Q.3
  • 11
    • 70149120831 scopus 로고    scopus 로고
    • Identification of an Aurora-A/PinsLINKER/Dlg spindle orientation pathway using induced cell polarity in S2 cells
    • (doi:10.1016/j.cell. 2009.07.041)
    • Johnston CA, Hirono K, Prehoda KE, Doe CQ. 2009 Identification of an Aurora-A/PinsLINKER/Dlg spindle orientation pathway using induced cell polarity in S2 cells. Cell 138, 1150-1163. (doi:10.1016/j.cell. 2009.07.041)
    • (2009) Cell , vol.138 , pp. 1150-1163
    • Johnston, C.A.1    Hirono, K.2    Prehoda, K.E.3    Doe, C.Q.4
  • 12
    • 35448993955 scopus 로고    scopus 로고
    • Gαi generates multiple Pins activation states to link cortical polarity and spindle orientation in Drosophila neuroblasts
    • (doi:10.1073/pnas.0701812104)
    • Nipper RW, Siller KH, Smith NR, Doe CQ, Prehoda KE. 2007 Gαi generates multiple Pins activation states to link cortical polarity and spindle orientation in Drosophila neuroblasts. Proc. Natl Acad. Sci USA 104, 14 306-14 311. (doi:10.1073/pnas.0701812104)
    • (2007) Proc. Natl Acad. Sci USA , vol.104 , pp. 14306-14311
    • Nipper, R.W.1    Siller, K.H.2    Smith, N.R.3    Doe, C.Q.4    Prehoda, K.E.5
  • 13
    • 8344271193 scopus 로고    scopus 로고
    • Mammalian Pins is a conformational switch that links NuMA to heterotrimeric G proteins
    • (doi:10.1016/j.cell.2004.10.028)
    • Du Q, Macara IG. 2004 Mammalian Pins is a conformational switch that links NuMA to heterotrimeric G proteins. Cell 119, 503-516. (doi:10.1016/j.cell.2004.10.028)
    • (2004) Cell , vol.119 , pp. 503-516
    • Du, Q.1    Macara, I.G.2
  • 14
    • 0020989882 scopus 로고
    • Mutations that affect neural cell lineages and cell fates during the development of the nematode Caenorhabditis elegans
    • (doi:10. 1101/SQB.1983.048.01.050)
    • Horvitz HR, Sternberg PW, Greenwald IS, Fixsen W, Ellis HM. 1983 Mutations that affect neural cell lineages and cell fates during the development of the nematode Caenorhabditis elegans. Cold Spring Harb. Symp. Quant. Biol. 48, 453-463. (doi:10. 1101/SQB.1983.048.01.050)
    • (1983) Cold Spring Harb. Symp. Quant. Biol. , vol.48 , pp. 453-463
    • Horvitz, H.R.1    Sternberg, P.W.2    Greenwald, I.S.3    Fixsen, W.4    Ellis, H.M.5
  • 15
    • 0034627760 scopus 로고    scopus 로고
    • LIN-5 is a novel component of the spindle apparatus required for chromosome segregation and cleavage plane specification in Caenorhabditis elegans
    • (doi:10.1083/jcb. 148.1.73)
    • Lorson MA, Horvitz HR, van den Heuvel S. 2000 LIN-5 is a novel component of the spindle apparatus required for chromosome segregation and cleavage plane specification in Caenorhabditis elegans. J. Cell Biol. 148, 73-86. (doi:10.1083/jcb. 148.1.73)
    • (2000) J. Cell Biol. , vol.148 , pp. 73-86
    • Lorson, M.A.1    Horvitz, H.R.2    van den Heuvel, S.3
  • 16
    • 33646861011 scopus 로고    scopus 로고
    • The Drosophila NuMA homolog Mud regulates spindle orientation in asymmetric cell division
    • (doi:10.1016/j. devcel.2006.05.005)
    • Bowman SK, Neumüller RA, Novatchkova M, Du Q, Knoblich JA. 2006 The Drosophila NuMA homolog Mud regulates spindle orientation in asymmetric cell division. Dev. Cell 10, 731-742. (doi:10.1016/j. devcel.2006.05.005)
    • (2006) Dev. Cell , vol.10 , pp. 731-742
    • Bowman, S.K.1    Neumüller, R.A.2    Novatchkova, M.3    Du, Q.4    Knoblich, J.A.5
  • 17
    • 33751117796 scopus 로고    scopus 로고
    • Spindle oscillations during asymmetric cell division require a threshold number of active cortical force generators
    • (doi:10.1016/j.cub.2006.09.030)
    • Pecreaux J, Röper J-C, Kruse K, Jülicher F, Hyman AA, Grill SW, Howard J. 2006 Spindle oscillations during asymmetric cell division require a threshold number of active cortical force generators. Curr. Biol. 16, 2111-2122. (doi:10.1016/j.cub.2006.09.030)
    • (2006) Curr. Biol. , vol.16 , pp. 2111-2122
    • Pecreaux, J.1    Röper, J.-C.2    Kruse, K.3    Jülicher, F.4    Hyman, A.A.5    Grill, S.W.6    Howard, J.7
  • 18
    • 84857788913 scopus 로고    scopus 로고
    • Chromosomeand spindle-pole-derived signals generate an intrinsic code for spindle position and orientation
    • (doi:10.1038/ncb2440)
    • Kiyomitsu T, Cheeseman IM. 2012 Chromosomeand spindle-pole-derived signals generate an intrinsic code for spindle position and orientation. Nat. Cell Biol. 14, 311-317. (doi:10.1038/ncb2440)
    • (2012) Nat. Cell Biol. , vol.14 , pp. 311-317
    • Kiyomitsu, T.1    Cheeseman, I.M.2
  • 19
    • 84869121021 scopus 로고    scopus 로고
    • Cortical dynein is critical for proper spindle positioning in human cells
    • (doi:10.1083/jcb. 201203166)
    • Kotak S, Busso C, Gönczy P. 2012 Cortical dynein is critical for proper spindle positioning in human cells. J. Cell Biol. 199, 97-110. (doi:10.1083/jcb. 201203166)
    • (2012) J. Cell Biol. , vol.199 , pp. 97-110
    • Kotak, S.1    Busso, C.2    Gönczy, P.3
  • 20
    • 0034611690 scopus 로고    scopus 로고
    • A protein complex containing Inscuteable and the Gα-binding protein Pins orients asymmetric cell divisions in Drosophila
    • (doi:10.1016/S0960-9822(00)00401-2)
    • Schaefer M, Shevchenko A, Shevchenko A, Knoblich JA. 2000 A protein complex containing Inscuteable and the Gα-binding protein Pins orients asymmetric cell divisions in Drosophila. Curr. Biol. 10, 353-362. (doi:10.1016/S0960-9822(00)00401-2)
    • (2000) Curr. Biol. , vol.10 , pp. 353-362
    • Schaefer, M.1    Shevchenko, A.2    Shevchenko, A.3    Knoblich, J.A.4
  • 21
    • 0041977037 scopus 로고    scopus 로고
    • Distinct roles of Gαi and Gβ13F subunits of the heterotrimeric G protein complex in the mediation of Drosophila neuroblast asymmetric divisions
    • (doi:10.1083/jcb.200303174)
    • Yu F, Cai Y, Kaushik R, Yang X, Chia W. 2003 Distinct roles of Gαi and Gβ13F subunits of the heterotrimeric G protein complex in the mediation of Drosophila neuroblast asymmetric divisions. J. Cell Biol. 162, 623-633. (doi:10.1083/jcb.200303174)
    • (2003) J. Cell Biol. , vol.162 , pp. 623-633
    • Yu, F.1    Cai, Y.2    Kaushik, R.3    Yang, X.4    Chia, W.5
  • 22
    • 0034745355 scopus 로고    scopus 로고
    • Distinct roles for Gα and Gβγ in regulating spindle position and orientation in Caenorhabditis elegans embryos
    • (doi:10.1038/35060092)
    • Gotta M, Ahringer J. 2001 Distinct roles for Gα and Gβγ in regulating spindle position and orientation in Caenorhabditis elegans embryos. Nat. Cell Biol. 3, 297-300. (doi:10.1038/35060092)
    • (2001) Nat. Cell Biol. , vol.3 , pp. 297-300
    • Gotta, M.1    Ahringer, J.2
  • 23
    • 0034533704 scopus 로고    scopus 로고
    • oα) in regulating a subset of centrosome movements during early embryogenesis in Caenorhabditis elegans
    • oα) in regulating a subset of centrosome movements during early embryogenesis in Caenorhabditis elegans. Genetics 156, 1649-1660.
    • (2000) Genetics , vol.156 , pp. 1649-1660
    • Miller, K.G.1    Rand, J.B.2
  • 24
    • 6944256893 scopus 로고    scopus 로고
    • Control of embryonic spindle positioning and Gα activity by C. elegans RIC-8
    • (doi:10.1016/j.cub.2004.09.059)
    • Couwenbergs C, Spilker AC, Gotta M. 2004 Control of embryonic spindle positioning and Gα activity by C. elegans RIC-8. Curr. Biol. 14, 1871-1876. (doi:10.1016/j.cub.2004.09.059)
    • (2004) Curr. Biol. , vol.14 , pp. 1871-1876
    • Couwenbergs, C.1    Spilker, A.C.2    Gotta, M.3
  • 25
    • 5444260164 scopus 로고    scopus 로고
    • RIC-8 is required for GPR-1/2-dependent Gα function during asymmetric division of C. elegans embryos
    • (doi:10.1016/j.cell.2004.09.026)
    • Afshar K, Willard FS, Colombo K, Johnston CA, McCudden CR, Siderovski DP, Gönczy P. 2004 RIC-8 is required for GPR-1/2-dependent Gα function during asymmetric division of C. elegans embryos. Cell 119, 219-230. (doi:10.1016/j.cell.2004.09.026)
    • (2004) Cell , vol.119 , pp. 219-230
    • Afshar, K.1    Willard, F.S.2    Colombo, K.3    Johnston, C.A.4    McCudden, C.R.5    Siderovski, D.P.6    Gönczy, P.7
  • 26
    • 77954357112 scopus 로고    scopus 로고
    • Ric-8A and Giα recruit LGN, NuMA, and dynein to the cell cortex to help orient the mitotic spindle
    • (doi:10.1128/MCB.00394-10)
    • Woodard GE, Huang N-N, Cho H, Miki T, Tall GG, Kehrl JH. 2010 Ric-8A and Giα recruit LGN, NuMA, and dynein to the cell cortex to help orient the mitotic spindle. Mol. Cell. Biol. 30, 3519-3530. (doi:10.1128/MCB.00394-10)
    • (2010) Mol. Cell. Biol. , vol.30 , pp. 3519-3530
    • Woodard, G.E.1    Huang, N.-N.2    Cho, H.3    Miki, T.4    Tall, G.G.5    Kehrl, J.H.6
  • 27
    • 28844482414 scopus 로고    scopus 로고
    • Ric-8 controls Drosophila neural progenitor asymmetric division by regulating heterotrimeric G proteins
    • (doi:10.1038/ ncb1317)
    • Wang H, Ng KH, Qian H, Siderovski DP, Chia W, Yu F. 2005 Ric-8 controls Drosophila neural progenitor asymmetric division by regulating heterotrimeric G proteins. Nat. Cell Biol. 7, 1091-1098. (doi:10.1038/ ncb1317)
    • (2005) Nat. Cell Biol. , vol.7 , pp. 1091-1098
    • Wang, H.1    Ng, K.H.2    Qian, H.3    Siderovski, D.P.4    Chia, W.5    Yu, F.6
  • 28
    • 77953283628 scopus 로고    scopus 로고
    • Cell polarity in eggs and epithelia: Parallels and diversity
    • (doi:10.1016/j.cell.2010.05.011)
    • St Johnston D, Ahringer J. 2010 Cell polarity in eggs and epithelia: parallels and diversity. Cell 141, 757-774. (doi:10.1016/j.cell.2010.05.011)
    • (2010) Cell , vol.141 , pp. 757-774
    • St Johnston, D.1    Ahringer, J.2
  • 29
    • 84871914189 scopus 로고    scopus 로고
    • Epithelial cell polarity: What flies can teach us about cancer
    • (doi:10.1042/ bse0530129)
    • Bergstralh DT, St Johnston D. 2012 Epithelial cell polarity: what flies can teach us about cancer. Essays Biochem. 53, 129-140. (doi:10.1042/ bse0530129)
    • (2012) Essays Biochem. , vol.53 , pp. 129-140
    • Bergstralh, D.T.1    St Johnston, D.2
  • 30
    • 77951911203 scopus 로고    scopus 로고
    • aPKC phosphorylation of Bazooka defines the apical/lateral border in Drosophila epithelial cells
    • (doi:10.1016/j.cell.2010.02.040)
    • Morais-de-Sá E, Mirouse V, St Johnston D. 2010 aPKC phosphorylation of Bazooka defines the apical/lateral border in Drosophila epithelial cells. Cell 141, 509-523. (doi:10.1016/j.cell.2010.02.040)
    • (2010) Cell , vol.141 , pp. 509-523
    • Morais-de-Sá, E.1    Mirouse, V.2    St Johnston, D.3
  • 31
    • 77956372591 scopus 로고    scopus 로고
    • Formation of a Bazooka-Stardust complex is essential for plasma membrane polarity in epithelia
    • (doi:10.1083/jcb.201006029)
    • Krahn MP, Buckers J, Kastrup L, Wodarz A. 2010 Formation of a Bazooka-Stardust complex is essential for plasma membrane polarity in epithelia. J. Cell Biol. 190, 751-760. (doi:10.1083/jcb.201006029)
    • (2010) J. Cell Biol. , vol.190 , pp. 751-760
    • Krahn, M.P.1    Buckers, J.2    Kastrup, L.3    Wodarz, A.4
  • 32
    • 77955714079 scopus 로고    scopus 로고
    • Crumbs/DaPKCdependent apical exclusion of Bazooka promotes photoreceptor polarity remodeling
    • (doi:10.1016/j.cub.2010.04.049)
    • Walther RF, Pichaud F. 2010 Crumbs/DaPKCdependent apical exclusion of Bazooka promotes photoreceptor polarity remodeling. Curr. Biol. 20, 1065-1074. (doi:10.1016/j.cub.2010.04.049)
    • (2010) Curr. Biol. , vol.20 , pp. 1065-1074
    • Walther, R.F.1    Pichaud, F.2
  • 33
    • 84875453508 scopus 로고    scopus 로고
    • Rap1 and Canoe/afadin are essential for establishment of apical-basal polarity in the Drosophila embryo
    • (doi:10.1091/mbc.E12-10-0736)
    • Choi W, Harris NJ, Sumigray KD, Peifer M. 2013 Rap1 and Canoe/afadin are essential for establishment of apical-basal polarity in the Drosophila embryo. Mol. Biol. Cell 24, 945-963. (doi:10.1091/mbc.E12-10-0736)
    • (2013) Mol. Biol. Cell , vol.24 , pp. 945-963
    • Choi, W.1    Harris, N.J.2    Sumigray, K.D.3    Peifer, M.4
  • 34
    • 0034617129 scopus 로고    scopus 로고
    • Cooperative regulation of cell polarity and growth by Drosophila tumor suppressors
    • (doi:10. 1126/science.289.5476.113)
    • Bilder D, Li M, Perrimon N. 2000 Cooperative regulation of cell polarity and growth by Drosophila tumor suppressors. Science 289, 113-116. (doi:10. 1126/science.289.5476.113)
    • (2000) Science , vol.289 , pp. 113-116
    • Bilder, D.1    Li, M.2    Perrimon, N.3
  • 35
    • 84871843234 scopus 로고    scopus 로고
    • Cell polarity and asymmetric cell division: The C. elegans early embryo
    • (doi:10.1042/ bse0530001)
    • Noatynska A, Gotta M. 2012 Cell polarity and asymmetric cell division: the C. elegans early embryo. Essays Biochem. 53, 1-14. (doi:10.1042/ bse0530001)
    • (2012) Essays Biochem. , vol.53 , pp. 1-14
    • Noatynska, A.1    Gotta, M.2
  • 36
    • 0035252546 scopus 로고    scopus 로고
    • Polarity controls forces governing asymmetric spindle positioning in the Caenorhabditis elegans embryo
    • (doi:10.1038/ 35054572)
    • Grill SW, Gönczy P, Stelzer EH, Hyman AA. 2001 Polarity controls forces governing asymmetric spindle positioning in the Caenorhabditis elegans embryo. Nature 409, 630-633. (doi:10.1038/ 35054572)
    • (2001) Nature , vol.409 , pp. 630-633
    • Grill, S.W.1    Gönczy, P.2    Stelzer, E.H.3    Hyman, A.A.4
  • 37
    • 0042845879 scopus 로고    scopus 로고
    • The distribution of active force generators controls mitotic spindle position
    • (doi:10.1126/science.1086560)
    • Grill SW, Howard J, Schäffer E, Stelzer EHK, Hyman AA. 2003 The distribution of active force generators controls mitotic spindle position. Science 301, 518-521. (doi:10.1126/science.1086560)
    • (2003) Science , vol.301 , pp. 518-521
    • Grill, S.W.1    Howard, J.2    Schäffer, E.3    Stelzer, E.H.K.4    Hyman, A.A.5
  • 38
    • 35548975477 scopus 로고    scopus 로고
    • Coupling of cortical dynein and Gα proteins mediates spindle positioning in Caenorhabditis elegans
    • (doi:10.1038/ncb1649)
    • Nguyen-Ngoc T, Afshar K, Gönczy P. 2007 Coupling of cortical dynein and Gα proteins mediates spindle positioning in Caenorhabditis elegans. Nat. Cell Biol. 9, 1294-1302. (doi:10.1038/ncb1649)
    • (2007) Nat. Cell Biol. , vol.9 , pp. 1294-1302
    • Nguyen-Ngoc, T.1    Afshar, K.2    Gönczy, P.3
  • 39
    • 77957930053 scopus 로고    scopus 로고
    • Membrane invaginations reveal cortical sites that pull on mitotic spindles in one-cell C. elegans embryos
    • (doi:10.1371/journal.pone. 0012301)
    • Redemann S, Pecreaux J, Goehring NW, Khairy K, Stelzer EHK, Hyman AA, Howard J. 2010 Membrane invaginations reveal cortical sites that pull on mitotic spindles in one-cell C. elegans embryos. PLoS ONE 5, e12301. (doi:10.1371/journal.pone. 0012301)
    • (2010) PLoS ONE , vol.5
    • Redemann, S.1    Pecreaux, J.2    Goehring, N.W.3    Khairy, K.4    Stelzer, E.H.K.5    Hyman, A.A.6    Howard, J.7
  • 40
    • 0024284814 scopus 로고
    • Identification of genes required for cytoplasmic localization in early C. elegans embryos
    • Kemphues KJ, Priess JR, Morton DG, Cheng NS. 1988 Identification of genes required for cytoplasmic localization in early C. elegans embryos. Cell 52, 311-320.
    • (1988) Cell , vol.52 , pp. 311-320
    • Kemphues, K.J.1    Priess, J.R.2    Morton, D.G.3    Cheng, N.S.4
  • 41
    • 35549001736 scopus 로고    scopus 로고
    • The PAR proteins: Fundamental players in animal cell polarization
    • (doi:10.1016/j.devcel. 2007.10.007)
    • Goldstein B, Macara IG. 2007 The PAR proteins: fundamental players in animal cell polarization. Dev. Cell 13, 609-622. (doi:10.1016/j.devcel. 2007.10.007)
    • (2007) Dev. Cell , vol.13 , pp. 609-622
    • Goldstein, B.1    Macara, I.G.2
  • 42
    • 0031954429 scopus 로고    scopus 로고
    • The let-99 gene is required for proper spindle orientation during cleavage of the C. elegans embryo
    • Rose LS, Kemphues K. 1998 The let-99 gene is required for proper spindle orientation during cleavage of the C. elegans embryo. Development 125, 1337-1346.
    • (1998) Development , vol.125 , pp. 1337-1346
    • Rose, L.S.1    Kemphues, K.2
  • 43
    • 0036798722 scopus 로고    scopus 로고
    • LET-99 determines spindle position and is asymmetrically enriched in response to PAR polarity cues in C. elegans embryos
    • Tsou M-FB, Hayashi A, DeBella LR, McGrath G, Rose LS. 2002 LET-99 determines spindle position and is asymmetrically enriched in response to PAR polarity cues in C. elegans embryos. Development 129, 4469-4481.
    • (2002) Development , vol.129 , pp. 4469-4481
    • Tsou, M.-F.B.1    Hayashi, A.2    DeBella, L.R.3    McGrath, G.4    Rose, L.S.5
  • 44
    • 39249083863 scopus 로고    scopus 로고
    • Dynamic localization of LIN-5 and GPR-1/2 to cortical force generation domains during spindle positioning
    • (doi:10.1016/j.ydbio.2007.11.037)
    • Park DH, Rose LS. 2008 Dynamic localization of LIN-5 and GPR-1/2 to cortical force generation domains during spindle positioning. Dev. Biol. 315, 42-54. (doi:10.1016/j.ydbio.2007.11.037)
    • (2008) Dev. Biol. , vol.315 , pp. 42-54
    • Park, D.H.1    Rose, L.S.2
  • 45
    • 77951823707 scopus 로고    scopus 로고
    • LET-99 inhibits lateral posterior pulling forces during asymmetric spindle elongation in C. elegans embryos
    • (doi:10.1083/ jcb.201001115)
    • Krueger LE, Wu J-C, Tsou M-FB, Rose LS. 2010 LET-99 inhibits lateral posterior pulling forces during asymmetric spindle elongation in C. elegans embryos. J. Cell Biol. 189, 481-495. (doi:10.1083/ jcb.201001115)
    • (2010) J. Cell Biol. , vol.189 , pp. 481-495
    • Krueger, L.E.1    Wu, J.-C.2    Tsou, M.-F.B.3    Rose, L.S.4
  • 46
    • 80052494501 scopus 로고    scopus 로고
    • aPKC phosphorylates NuMA-related LIN-5 to position the mitotic spindle during asymmetric division
    • (doi:10.1038/ncb2315)
    • Galli M, Muñoz J, Portegijs V, Boxem M, Grill SW, Heck AJR, van den Heuvel S. 2011 aPKC phosphorylates NuMA-related LIN-5 to position the mitotic spindle during asymmetric division. Nat. Cell Biol. 13, 1132-1138. (doi:10.1038/ncb2315)
    • (2011) Nat. Cell Biol. , vol.13 , pp. 1132-1138
    • Galli, M.1    Muñoz, J.2    Portegijs, V.3    Boxem, M.4    Grill, S.W.5    Heck, A.J.R.6    van den Heuvel, S.7
  • 47
    • 0025774706 scopus 로고
    • The prospero gene specifies cell fates in the Drosophila central nervous system
    • (doi:10.1016/0092-8674(91)90463-9)
    • Doe CQ, Chu-LaGraff Q, Wright DM, Scott MP. 1991 The prospero gene specifies cell fates in the Drosophila central nervous system. Cell 65, 451-464. (doi:10.1016/0092-8674(91)90463-9)
    • (1991) Cell , vol.65 , pp. 451-464
    • Doe, C.Q.1    Chu-LaGraff, Q.2    Wright, D.M.3    Scott, M.P.4
  • 48
    • 0026361046 scopus 로고
    • The prospero gene encodes a divergent homeodomain protein that controls neuronal identity in Drosophila
    • Chu-LaGraff Q, Wright DM, McNeil LK, Doe CQ. 1991 The prospero gene encodes a divergent homeodomain protein that controls neuronal identity in Drosophila. Development Suppl. 2, 79-85.
    • (1991) Development , Issue.SUPPL. 2 , pp. 79-85
    • Chu-LaGraff, Q.1    Wright, D.M.2    McNeil, L.K.3    Doe, C.Q.4
  • 49
    • 0028803382 scopus 로고
    • The prospero transcription factor is asymmetrically localized to the cell cortex during neuroblast mitosis in Drosophila
    • Spana EP, Doe CQ. 1995 The prospero transcription factor is asymmetrically localized to the cell cortex during neuroblast mitosis in Drosophila. Development 121, 3187-3195.
    • (1995) Development , vol.121 , pp. 3187-3195
    • Spana, E.P.1    Doe, C.Q.2
  • 50
    • 0028785304 scopus 로고
    • Asymmetric segregation of the homeodomain protein Prospero during Drosophila development
    • (doi:10.1038/377627a0)
    • Hirata J, Nakagoshi H, Nabeshima Y, Matsuzaki F. 1995 Asymmetric segregation of the homeodomain protein Prospero during Drosophila development. Nature 377, 627-630. (doi:10.1038/377627a0)
    • (1995) Nature , vol.377 , pp. 627-630
    • Hirata, J.1    Nakagoshi, H.2    Nabeshima, Y.3    Matsuzaki, F.4
  • 51
    • 0028818805 scopus 로고
    • Asymmetric segregation of Numb and Prospero during cell division
    • (doi:10.1038/ 377624a0)
    • Knoblich JA, Jan LY, Jan YN. 1995 Asymmetric segregation of Numb and Prospero during cell division. Nature 377, 624-627. (doi:10.1038/ 377624a0)
    • (1995) Nature , vol.377 , pp. 624-627
    • Knoblich, J.A.1    Jan, L.Y.2    Jan, Y.N.3
  • 52
    • 0034650760 scopus 로고    scopus 로고
    • Pan-neural Prospero terminates cell proliferation during Drosophila neurogenesis
    • Li L, Vaessin H. 2000 Pan-neural Prospero terminates cell proliferation during Drosophila neurogenesis. Genes Dev. 14, 147-151.
    • (2000) Genes Dev. , vol.14 , pp. 147-151
    • Li, L.1    Vaessin, H.2
  • 53
    • 33751330924 scopus 로고    scopus 로고
    • Prospero acts as a binary switch between selfrenewal and differentiation in Drosophila neural stem cells
    • (doi:10.1016/j. devcel.2006.09.015)
    • Choksi SP, Southall TD, Bossing T, Edoff K, de Wit E, Fischer BE, van Steensel B, Micklem G, Brand AH. 2006 Prospero acts as a binary switch between selfrenewal and differentiation in Drosophila neural stem cells. Dev. Cell 11, 775-789. (doi:10.1016/j. devcel.2006.09.015)
    • (2006) Dev. Cell , vol.11 , pp. 775-789
    • Choksi, S.P.1    Southall, T.D.2    Bossing, T.3    Edoff, K.4    de Wit, E.5    Fischer, B.E.6    van Steensel, B.7    Micklem, G.8    Brand, A.H.9
  • 54
    • 33645525794 scopus 로고    scopus 로고
    • Brat is a Miranda cargo protein that promotes neuronal differentiation and inhibits neuroblast self-renewal
    • (doi:10.1016/j.devcel.2006.01.017)
    • Lee C-Y, Wilkinson BD, Siegrist SE, Wharton RP, Doe CQ. 2006 Brat is a Miranda cargo protein that promotes neuronal differentiation and inhibits neuroblast self-renewal. Dev. Cell 10, 441-449. (doi:10.1016/j.devcel.2006.01.017)
    • (2006) Dev. Cell , vol.10 , pp. 441-449
    • Lee, C.-Y.1    Wilkinson, B.D.2    Siegrist, S.E.3    Wharton, R.P.4    Doe, C.Q.5
  • 55
    • 33745485289 scopus 로고    scopus 로고
    • The brain tumor gene negatively regulates neural progenitor cell proliferation in the larval central brain of Drosophila
    • (doi:10.1242/ dev.02429)
    • Bello B, Reichert H, Hirth F. 2006 The brain tumor gene negatively regulates neural progenitor cell proliferation in the larval central brain of Drosophila. Development 133, 2639-2648. (doi:10.1242/ dev.02429)
    • (2006) Development , vol.133 , pp. 2639-2648
    • Bello, B.1    Reichert, H.2    Hirth, F.3
  • 56
    • 33646027006 scopus 로고    scopus 로고
    • Asymmetric segregation of the tumor suppressor Brat regulates self-renewal in Drosophila neural stem cells
    • (doi:10.1016/j. cell.2006.01.038)
    • Betschinger J, Mechtler K, Knoblich JA. 2006 Asymmetric segregation of the tumor suppressor Brat regulates self-renewal in Drosophila neural stem cells. Cell 124, 1241-1253. (doi:10.1016/j. cell.2006.01.038)
    • (2006) Cell , vol.124 , pp. 1241-1253
    • Betschinger, J.1    Mechtler, K.2    Knoblich, J.A.3
  • 57
    • 0027947609 scopus 로고
    • Asymmetric distribution of Numb protein during division of the sensory organ precursor cell confers distinct fates to daughter cells
    • (doi:10.1016/ 0092-8674(94)90112-0)
    • Rhyu MS, Jan LY, Jan YN. 1994 Asymmetric distribution of Numb protein during division of the sensory organ precursor cell confers distinct fates to daughter cells. Cell 76, 477-491. (doi:10.1016/ 0092-8674(94)90112-0)
    • (1994) Cell , vol.76 , pp. 477-491
    • Rhyu, M.S.1    Jan, L.Y.2    Jan, Y.N.3
  • 58
    • 0024980213 scopus 로고
    • Numb, a gene required in determination of cell fate during sensory organ formation in Drosophila embryos
    • (doi:10. 1016/0092-8674(89)90849-0)
    • Uemura T, Shepherd S, Ackerman L, Jan LY, Jan YN. 1989 numb, a gene required in determination of cell fate during sensory organ formation in Drosophila embryos. Cell 58, 349-360. (doi:10. 1016/0092-8674(89)90849-0)
    • (1989) Cell , vol.58 , pp. 349-360
    • Uemura, T.1    Shepherd, S.2    Ackerman, L.3    Jan, L.Y.4    Jan, Y.N.5
  • 59
    • 0028802562 scopus 로고
    • Asymmetric localization of numb autonomously determines sibling neuron identity in the Drosophila CNS
    • Spana EP, Kopczynski C, Goodman CS, Doe CQ. 1995 Asymmetric localization of numb autonomously determines sibling neuron identity in the Drosophila CNS. Development 121, 3489-3494.
    • (1995) Development , vol.121 , pp. 3489-3494
    • Spana, E.P.1    Kopczynski, C.2    Goodman, C.S.3    Doe, C.Q.4
  • 60
    • 0030199995 scopus 로고    scopus 로고
    • Numb antagonizes Notch signaling to specify sibling neuron cell fates
    • (doi:10.1016/S0896-6273(00)80277-9)
    • Spana EP, Doe CQ. 1996 Numb antagonizes Notch signaling to specify sibling neuron cell fates. Neuron 17, 21-26. (doi:10.1016/S0896-6273(00)80277-9)
    • (1996) Neuron , vol.17 , pp. 21-26
    • Spana, E.P.1    Doe, C.Q.2
  • 61
    • 2642620243 scopus 로고    scopus 로고
    • Binary sibling neuronal cell fate decisions in the Drosophila embryonic central nervous system are nonstochastic and require inscuteable-mediated asymmetry of ganglion mother cells
    • (doi:10.1101/gad.12.12.1858)
    • Buescher M, Yeo SL, Udolph G, Zavortink M, Yang X, Tear G, Chia W. 1998 Binary sibling neuronal cell fate decisions in the Drosophila embryonic central nervous system are nonstochastic and require inscuteable-mediated asymmetry of ganglion mother cells. Genes Dev. 12, 1858-1870. (doi:10.1101/gad.12.12.1858)
    • (1998) Genes Dev. , vol.12 , pp. 1858-1870
    • Buescher, M.1    Yeo, S.L.2    Udolph, G.3    Zavortink, M.4    Yang, X.5    Tear, G.6    Chia, W.7
  • 62
    • 0031471138 scopus 로고    scopus 로고
    • Miranda directs Prospero to a daughter cell during Drosophila asymmetric divisions
    • (doi:10. 1038/37641)
    • Ikeshima-Kataoka H, Skeath JB, Nabeshima Y, Doe CQ, Matsuzaki F. 1997 Miranda directs Prospero to a daughter cell during Drosophila asymmetric divisions. Nature 390, 625-629. (doi:10. 1038/37641)
    • (1997) Nature , vol.390 , pp. 625-629
    • Ikeshima-Kataoka, H.1    Skeath, J.B.2    Nabeshima, Y.3    Doe, C.Q.4    Matsuzaki, F.5
  • 63
    • 0030812318 scopus 로고    scopus 로고
    • Miranda is required for the asymmetric localization of Prospero during mitosis in Drosophila
    • (doi:10.1016/S0092-8674(00)80505-X)
    • Shen CP, Jan LY, Jan YN. 1997 Miranda is required for the asymmetric localization of Prospero during mitosis in Drosophila. Cell 90, 449-458. (doi:10.1016/S0092-8674(00)80505-X)
    • (1997) Cell , vol.90 , pp. 449-458
    • Shen, C.P.1    Jan, L.Y.2    Jan, Y.N.3
  • 64
    • 33846513022 scopus 로고    scopus 로고
    • aPKC-mediated phosphorylation regulates asymmetric membrane localization of the cell fate determinant Numb
    • (doi:10.1038/sj.emboj. 7601495)
    • Smith CA et al. 2007 aPKC-mediated phosphorylation regulates asymmetric membrane localization of the cell fate determinant Numb. EMBO J. 26, 468-480. (doi:10.1038/sj.emboj. 7601495)
    • (2007) EMBO J. , vol.26 , pp. 468-480
    • Smith, C.A.1
  • 65
    • 67349132552 scopus 로고    scopus 로고
    • aPKC phosphorylates Miranda to polarize fate determinants during neuroblast asymmetric cell division
    • (doi:10.1016/j.cub.2009.03.056)
    • Atwood SX, Prehoda KE. 2009 aPKC phosphorylates Miranda to polarize fate determinants during neuroblast asymmetric cell division. Curr. Biol. 19, 723-729. (doi:10.1016/j.cub.2009.03.056)
    • (2009) Curr. Biol. , vol.19 , pp. 723-729
    • Atwood, S.X.1    Prehoda, K.E.2
  • 66
    • 36448970103 scopus 로고    scopus 로고
    • Insights into neural stem cell biology from flies
    • (doi:10.1098/rstb. 2006.2011)
    • Egger B, Chell JM, Brand AH. 2008 Insights into neural stem cell biology from flies. Phil. Trans. R. Soc. B 363, 39-56. (doi:10.1098/rstb. 2006.2011)
    • (2008) Phil. Trans. R. Soc. B , vol.363 , pp. 39-56
    • Egger, B.1    Chell, J.M.2    Brand, A.H.3
  • 67
    • 0029821914 scopus 로고    scopus 로고
    • Role of inscuteable in orienting asymmetric cell divisions in Drosophila
    • (doi:10. 1038/383050a0)
    • Kraut R, Chia W, Jan LY, Jan YN, Knoblich JA. 1996 Role of inscuteable in orienting asymmetric cell divisions in Drosophila. Nature 383, 50-55. (doi:10. 1038/383050a0)
    • (1996) Nature , vol.383 , pp. 50-55
    • Kraut, R.1    Chia, W.2    Jan, L.Y.3    Jan, Y.N.4    Knoblich, J.A.5
  • 68
    • 0033518223 scopus 로고    scopus 로고
    • Bazooka provides an apical cue for Inscuteable localization in Drosophila neuroblasts
    • (doi:10.1038/990128)
    • Wodarz A, Ramrath A, Kuchinke U, Knust E. 1999 Bazooka provides an apical cue for Inscuteable localization in Drosophila neuroblasts. Nature 402, 544-547. (doi:10.1038/990128)
    • (1999) Nature , vol.402 , pp. 544-547
    • Wodarz, A.1    Ramrath, A.2    Kuchinke, U.3    Knust, E.4
  • 69
    • 0033518187 scopus 로고    scopus 로고
    • Bazooka recruits Inscuteable to orient asymmetric cell divisions in Drosophila neuroblasts
    • (doi:10.1038/990135)
    • Schober M, Schaefer M, Knoblich JA. 1999 Bazooka recruits Inscuteable to orient asymmetric cell divisions in Drosophila neuroblasts. Nature 402, 548-551. (doi:10.1038/990135)
    • (1999) Nature , vol.402 , pp. 548-551
    • Schober, M.1    Schaefer, M.2    Knoblich, J.A.3
  • 70
    • 79960913555 scopus 로고    scopus 로고
    • LGN/mInsc and LGN/NuMA complex structures suggest distinct functions in asymmetric cell division for the Par3/mInsc/LGN and Gαi/LGN/NuMA pathways
    • (doi:10.1016/j.molcel.2011.07.011)
    • Zhu J et al. 2011 LGN/mInsc and LGN/NuMA complex structures suggest distinct functions in asymmetric cell division for the Par3/mInsc/LGN and Gαi/LGN/NuMA pathways. Mol. Cell 43, 418-431. (doi:10.1016/j.molcel.2011.07.011)
    • (2011) Mol. Cell , vol.43 , pp. 418-431
    • Zhu, J.1
  • 71
    • 84855487476 scopus 로고    scopus 로고
    • Inscuteable and NuMA proteins bind competitively to Leu-Gly-Asn repeat-enriched protein (LGN) during asymmetric cell divisions
    • (doi:10. 1073/pnas.1113077108)
    • Culurgioni S, Alfieri A, Pendolino V, Laddomada F, Mapelli M. 2011 Inscuteable and NuMA proteins bind competitively to Leu-Gly-Asn repeat-enriched protein (LGN) during asymmetric cell divisions. Proc. Natl Acad. Sci. USA 108, 20 998-21 003. (doi:10. 1073/pnas.1113077108)
    • (2011) Proc. Natl Acad. Sci. USA , vol.108 , pp. 20998-21003
    • Culurgioni, S.1    Alfieri, A.2    Pendolino, V.3    Laddomada, F.4    Mapelli, M.5
  • 72
    • 82755163576 scopus 로고    scopus 로고
    • Structural basis for interaction between the conserved cell polarity proteins Inscuteable and Leu-Gly-Asn repeat-enriched protein (LGN)
    • (doi:10.1073/pnas.1110951108)
    • Yuzawa S, Kamakura S, Iwakiri Y, Hayase J, Sumimoto H. 2011 Structural basis for interaction between the conserved cell polarity proteins Inscuteable and Leu-Gly-Asn repeat-enriched protein (LGN). Proc. Natl Acad. Sci. USA 108, 19 210-19 215. (doi:10.1073/pnas.1110951108)
    • (2011) Proc. Natl Acad. Sci. USA , vol.108 , pp. 19210-19215
    • Yuzawa, S.1    Kamakura, S.2    Iwakiri, Y.3    Hayase, J.4    Sumimoto, H.5
  • 73
    • 52949115363 scopus 로고    scopus 로고
    • Linking cell cycle to asymmetric division: Aurora-A phosphorylates the Par complex to regulate Numb localization
    • (doi:10.1016/j.cell. 2008.07.049)
    • Wirtz-Peitz F, Nishimura T, Knoblich JA. 2008 Linking cell cycle to asymmetric division: Aurora-A phosphorylates the Par complex to regulate Numb localization. Cell 135, 161-173. (doi:10.1016/j.cell. 2008.07.049)
    • (2008) Cell , vol.135 , pp. 161-173
    • Wirtz-Peitz, F.1    Nishimura, T.2    Knoblich, J.A.3
  • 74
    • 35548977489 scopus 로고    scopus 로고
    • Cdc42 acts downstream of Bazooka to regulate neuroblast polarity through Par-6 aPKC
    • (doi:10.1242/jcs. 014902)
    • Atwood SX, Chabu C, Penkert RR, Doe CQ, Prehoda KE. 2007 Cdc42 acts downstream of Bazooka to regulate neuroblast polarity through Par-6 aPKC. J. Cell Sci. 120, 3200-3206. (doi:10.1242/jcs. 014902)
    • (2007) J. Cell Sci. , vol.120 , pp. 3200-3206
    • Atwood, S.X.1    Chabu, C.2    Penkert, R.R.3    Doe, C.Q.4    Prehoda, K.E.5
  • 75
    • 0034874862 scopus 로고    scopus 로고
    • PAR-6 regulates aPKC activity in a novel way and mediates cell-cell contact-induced formation of the epithelial junctional complex
    • (doi:10.1046/j.1365-2443.2001.00453.x)
    • Yamanaka T et al. 2001 PAR-6 regulates aPKC activity in a novel way and mediates cell-cell contact-induced formation of the epithelial junctional complex. Genes Cells 6, 721-731. (doi:10.1046/j.1365-2443.2001.00453.x)
    • (2001) Genes Cells , vol.6 , pp. 721-731
    • Yamanaka, T.1
  • 76
    • 84862281704 scopus 로고    scopus 로고
    • Partitioning-defective protein 6 (Par-6) activates atypical protein kinase C (aPKC) by pseudosubstrate displacement
    • (doi:10.1074/jbc.M112.360495)
    • Graybill C, Wee B, Atwood SX, Prehoda KE. 2012 Partitioning-defective protein 6 (Par-6) activates atypical protein kinase C (aPKC) by pseudosubstrate displacement. J. Biol. Chem. 287, 21 003-21 011. (doi:10.1074/jbc.M112.360495)
    • (2012) J. Biol. Chem. , vol.287 , pp. 21003-21011
    • Graybill, C.1    Wee, B.2    Atwood, S.X.3    Prehoda, K.E.4
  • 77
    • 0347480270 scopus 로고    scopus 로고
    • Drosophila aPKC regulates cell polarity and cell proliferation in neuroblasts and epithelia
    • (doi:10.1083/jcb.200306079)
    • Rolls MM, Albertson R, Shih H-P, Lee C-Y, Doe CQ. 2003 Drosophila aPKC regulates cell polarity and cell proliferation in neuroblasts and epithelia. J. Cell Biol. 163, 1089-1098. (doi:10.1083/jcb.200306079)
    • (2003) J. Cell Biol. , vol.163 , pp. 1089-1098
    • Rolls, M.M.1    Albertson, R.2    Shih, H.-P.3    Lee, C.-Y.4    Doe, C.Q.5
  • 78
    • 0037456795 scopus 로고    scopus 로고
    • The Par complex directs asymmetric cell division by phosphorylating the cytoskeletal protein Lgl
    • (doi:10.1038/nature01486)
    • Betschinger J, Mechtler K, Knoblich JA. 2003 The Par complex directs asymmetric cell division by phosphorylating the cytoskeletal protein Lgl. Nature 422, 326-330. (doi:10.1038/nature01486)
    • (2003) Nature , vol.422 , pp. 326-330
    • Betschinger, J.1    Mechtler, K.2    Knoblich, J.A.3
  • 79
    • 0034735789 scopus 로고    scopus 로고
    • Role of cortical tumour-suppressor proteins in asymmetric division of Drosophila neuroblast
    • (doi:10.1038/35046087)
    • Ohshiro T, Yagami T, Zhang C, Matsuzaki F. 2000 Role of cortical tumour-suppressor proteins in asymmetric division of Drosophila neuroblast. Nature 408, 593-596. (doi:10.1038/35046087)
    • (2000) Nature , vol.408 , pp. 593-596
    • Ohshiro, T.1    Yagami, T.2    Zhang, C.3    Matsuzaki, F.4
  • 80
    • 0034735753 scopus 로고    scopus 로고
    • The tumour-suppressor genes lgl and dlg regulate basal protein targeting in Drosophila neuroblasts
    • (doi:10.1038/35046094)
    • Peng CY, Manning L, Albertson R, Doe CQ. 2000 The tumour-suppressor genes lgl and dlg regulate basal protein targeting in Drosophila neuroblasts. Nature 408, 596-600. (doi:10.1038/35046094)
    • (2000) Nature , vol.408 , pp. 596-600
    • Peng, C.Y.1    Manning, L.2    Albertson, R.3    Doe, C.Q.4
  • 81
    • 0037318955 scopus 로고    scopus 로고
    • Dlg, Scrib and Lgl regulate neuroblast cell size and mitotic spindle asymmetry
    • (doi:10. 1038/ncb922)
    • Albertson R, Doe CQ. 2003 Dlg, Scrib and Lgl regulate neuroblast cell size and mitotic spindle asymmetry. Nat. Cell Biol. 5, 166-170. (doi:10. 1038/ncb922)
    • (2003) Nat. Cell Biol. , vol.5 , pp. 166-170
    • Albertson, R.1    Doe, C.Q.2
  • 82
    • 31844432828 scopus 로고    scopus 로고
    • Lgl, Pins and aPKC regulate neuroblast self-renewal versus differentiation
    • (doi:10.1038/ nature04299)
    • Lee C-Y, Robinson KJ, Doe CQ. 2006 Lgl, Pins and aPKC regulate neuroblast self-renewal versus differentiation. Nature 439, 594-598. (doi:10.1038/ nature04299)
    • (2006) Nature , vol.439 , pp. 594-598
    • Lee, C.-Y.1    Robinson, K.J.2    Doe, C.Q.3
  • 83
    • 44349147164 scopus 로고    scopus 로고
    • The PDZ protein Canoe regulates the asymmetric division of Drosophila neuroblasts and muscle progenitors
    • (doi:10.1016/ j.cub.2008.04.072)
    • Speicher S, Fischer A, Knoblich J, Carmena A. 2008 The PDZ protein Canoe regulates the asymmetric division of Drosophila neuroblasts and muscle progenitors. Curr. Biol. 18, 831-837. (doi:10.1016/ j.cub.2008.04.072)
    • (2008) Curr. Biol. , vol.18 , pp. 831-837
    • Speicher, S.1    Fischer, A.2    Knoblich, J.3    Carmena, A.4
  • 84
    • 84855718127 scopus 로고    scopus 로고
    • Canoe binds RanGTP to promote Pins(TPR)/Mudmediated spindle orientation
    • (doi:10.1083/jcb.201102130)
    • Wee B, Johnston CA, Prehoda KE, Doe CQ. 2011 Canoe binds RanGTP to promote Pins(TPR)/Mudmediated spindle orientation. J. Cell Biol. 195, 369-376. (doi:10.1083/jcb.201102130)
    • (2011) J. Cell Biol. , vol.195 , pp. 369-376
    • Wee, B.1    Johnston, C.A.2    Prehoda, K.E.3    Doe, C.Q.4
  • 85
    • 22244455455 scopus 로고    scopus 로고
    • Membraneassociated guanylate kinases regulate adhesion and plasticity at cell junctions
    • (doi:10.1146/annurev.biochem.74. 082803.133339)
    • Funke L, Dakoji S, Bredt DS. 2005 Membraneassociated guanylate kinases regulate adhesion and plasticity at cell junctions. Annu. Rev. Biochem. 74, 219-245. (doi:10.1146/annurev.biochem.74. 082803.133339)
    • (2005) Annu. Rev. Biochem. , vol.74 , pp. 219-245
    • Funke, L.1    Dakoji, S.2    Bredt, D.S.3
  • 86
    • 0035839053 scopus 로고    scopus 로고
    • The partner of Inscuteable/Discs-large complex is required to establish planar polarity during asymmetric cell division in Drosophila
    • (doi:10.1016/S0092-8674(01)00444-5)
    • Bellaïche Y, Radovic A, Woods DF, Hough CD, Parmentier ML, O'Kane CJ, Bryant PJ, Schweisguth F. 2001 The partner of Inscuteable/Discs-large complex is required to establish planar polarity during asymmetric cell division in Drosophila. Cell 106, 355-366. (doi:10.1016/S0092-8674(01)00444-5)
    • (2001) Cell , vol.106 , pp. 355-366
    • Bellaïche, Y.1    Radovic, A.2    Woods, D.F.3    Hough, C.D.4    Parmentier, M.L.5    O'Kane, C.J.6    Bryant, P.J.7    Schweisguth, F.8
  • 87
    • 29244469948 scopus 로고    scopus 로고
    • Microtubule-induced Pins/ Gαi cortical polarity in Drosophila neuroblasts
    • (doi:10.1016/j.cell.2005. 09.043)
    • Siegrist SE, Doe CQ. 2005 Microtubule-induced Pins/ Gαi cortical polarity in Drosophila neuroblasts. Cell 123, 1323-1335. (doi:10.1016/j.cell.2005. 09.043)
    • (2005) Cell , vol.123 , pp. 1323-1335
    • Siegrist, S.E.1    Doe, C.Q.2
  • 88
    • 0034666131 scopus 로고    scopus 로고
    • GAKIN, a novel kinesin-like protein associates with the human homologue of the Drosophila Discs large tumor suppressor in T lymphocytes
    • (doi:10.1074/jbc. M000715200)
    • Hanada T, Lin L, Tibaldi EV, Reinherz EL, Chishti AH. 2000 GAKIN, a novel kinesin-like protein associates with the human homologue of the Drosophila Discs large tumor suppressor in T lymphocytes. J. Biol. Chem. 275, 28 774-28 784. (doi:10.1074/jbc. M000715200)
    • (2000) J. Biol. Chem. , vol.275 , pp. 28774-28784
    • Hanada, T.1    Lin, L.2    Tibaldi, E.V.3    Reinherz, E.L.4    Chishti, A.H.5
  • 89
    • 78049255724 scopus 로고    scopus 로고
    • Par3 controls epithelial spindle orientation by aPKC-mediated phosphorylation of apical Pins
    • (doi:10.1016/j.cub. 2010.09.032)
    • Hao Y, Du Q, Chen X, Zheng Z, Balsbaugh JL, Maitra S, Shabanowitz J, Hunt DF, Macara IG. 2010 Par3 controls epithelial spindle orientation by aPKC-mediated phosphorylation of apical Pins. Curr. Biol. 20, 1809-1818. (doi:10.1016/j.cub. 2010.09.032)
    • (2010) Curr. Biol. , vol.20 , pp. 1809-1818
    • Hao, Y.1    Du, Q.2    Chen, X.3    Zheng, Z.4    Balsbaugh, J.L.5    Maitra, S.6    Shabanowitz, J.7    Hunt, D.F.8    Macara, I.G.9
  • 90
    • 79955497378 scopus 로고    scopus 로고
    • A lateral belt of cortical LGN and NuMA guides mitotic spindle movements and planar division in neuroepithelial cells
    • (doi:10.1083/jcb. 201101039)
    • Peyre E, Jaouen F, Saadaoui M, Haren L, Merdes A, Durbec P, Morin X. 2011 A lateral belt of cortical LGN and NuMA guides mitotic spindle movements and planar division in neuroepithelial cells. J. Cell Biol. 193, 141-154. (doi:10.1083/jcb. 201101039)
    • (2011) J. Cell Biol. , vol.193 , pp. 141-154
    • Peyre, E.1    Jaouen, F.2    Saadaoui, M.3    Haren, L.4    Merdes, A.5    Durbec, P.6    Morin, X.7
  • 91
    • 84855420819 scopus 로고    scopus 로고
    • Drosophila aPKC is required for mitotic spindle orientation during symmetric division of epithelial cells
    • (doi:10.1242/dev.071027)
    • Guilgur LG, Prudencio P, Ferreira T, Pimenta-Marques AR, Martinho RG. 2012 Drosophila aPKC is required for mitotic spindle orientation during symmetric division of epithelial cells. Development 139, 503-513. (doi:10.1242/dev.071027)
    • (2012) Development , vol.139 , pp. 503-513
    • Guilgur, L.G.1    Prudencio, P.2    Ferreira, T.3    Pimenta-Marques, A.R.4    Martinho, R.G.5


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