The PAR network: Redundancy and robustness in a symmetry-breaking system

Philosophical Transactions of the Royal Society B: Biological Sciences

Volumn 368, Issue 1629, 2013, Pages

  Motegi, Fumio ^a,b   Seydoux, Geraldine ^c  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cdc42; Feedback loops; Modelling of biological networks; PAR proteins; Polarity; Robustness

Indexed keywords

ANTAGONISM; CELL ORGANELLE; POLARIZATION; PROTEIN;

CAENORHABDITIS ELEGANS PROTEIN; PAR-1 PROTEIN, C ELEGANS; PROTEIN CDC42; PROTEIN SERINE THREONINE KINASE; PAR 1 PROTEIN, C ELEGANS;

ANIMAL; BIOLOGICAL MODEL; CAENORHABDITIS ELEGANS; CELL POLARITY; CENTROSOME; FEEDBACK SYSTEM; METABOLISM; PHYSIOLOGY; ZYGOTE; CDC42; FEEDBACK LOOPS; MODELLING OF BIOLOGICAL NETWORKS; PAR PROTEINS; POLARITY; REVIEW; ROBUSTNESS;

ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CDC42 GTP-BINDING PROTEIN, SACCHAROMYCES CEREVISIAE; CELL POLARITY; CENTROSOME; FEEDBACK, PHYSIOLOGICAL; MODELS, BIOLOGICAL; PROTEIN-SERINE-THREONINE KINASES; ZYGOTE;

CDC42; FEEDBACK LOOPS; MODELLING OF BIOLOGICAL NETWORKS; PAR PROTEINS; POLARITY; ROBUSTNESS;

EID: 84884487170     PISSN: 09628436     EISSN: 14712970     Source Type: Journal    
DOI: 10.1098/rstb.2013.0010     Document Type: Review

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