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Volumn 140, Issue 9, 2013, Pages 2005-2014

PAR-2, LGL-1 and the CDC-42 GAP CHIN-1 act in distinct pathways to maintain polarity in the C. elegans embryo

Author keywords

Embryo; PAR genes; Polarity

Indexed keywords

CGEF 1 PROTEIN; CHIN 1 PROTEIN; LGL 1 PROTEIN; MYOSIN II; PROTEIN; PROTEIN CDC42; PROTEINASE ACTIVATED RECEPTOR; PROTEINASE ACTIVATED RECEPTOR 2; PROTEINASE ACTIVATED RECEPTOR 3; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

EID: 84876001280     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.088310     Document Type: Article
Times cited : (30)

References (31)
  • 1
    • 33750331486 scopus 로고    scopus 로고
    • Interaction of PAR-6 with CDC-42 is required for maintenance but not establishment of PAR asymmetry in C. elegans
    • Aceto, D., Beers, M. and Kemphues, K. J. (2006). Interaction of PAR-6 with CDC-42 is required for maintenance but not establishment of PAR asymmetry in C. elegans. Dev. Biol. 299, 386-397.
    • (2006) Dev. Biol. , vol.299 , pp. 386-397
    • Aceto, D.1    Beers, M.2    Kemphues, K.J.3
  • 2
    • 78649890169 scopus 로고    scopus 로고
    • The C. elegans homolog of Drosophila Lethal giant larvae functions redundantly with PAR-2 to maintain polarity in the early embryo
    • Beatty, A., Morton, D. and Kemphues, K. (2010). The C. elegans homolog of Drosophila Lethal giant larvae functions redundantly with PAR-2 to maintain polarity in the early embryo. Development 137, 3995-4004.
    • (2010) Development , vol.137 , pp. 3995-4004
    • Beatty, A.1    Morton, D.2    Kemphues, K.3
  • 3
    • 10344236460 scopus 로고    scopus 로고
    • PAR-2 is asymmetrically distributed and promotes association of P granules and PAR-1 with the cortex in C. elegans embryos
    • Boyd, L., Guo, S., Levitan, D., Stinchcomb, D. T. and Kemphues, K. J. (1996). PAR-2 is asymmetrically distributed and promotes association of P granules and PAR-1 with the cortex in C. elegans embryos. Development 122, 3075-3084.
    • (1996) Development , vol.122 , pp. 3075-3084
    • Boyd, L.1    Guo, S.2    Levitan, D.3    Stinchcomb, D.T.4    Kemphues, K.J.5
  • 4
    • 0016063911 scopus 로고
    • The genetics of Caenorhabditis elegans
    • Brenner, S. (1974). The genetics of Caenorhabditis elegans. Genetics 77, 71-94.
    • (1974) Genetics , vol.77 , pp. 71-94
    • Brenner, S.1
  • 5
    • 3042598129 scopus 로고    scopus 로고
    • C. elegans PAR proteins function by mobilizing and stabilizing asymmetrically localized protein complexes
    • Cheeks, R. J., Canman, J. C., Gabriel, W. N., Meyer, N., Strome, S. and Goldstein, B. (2004). C. elegans PAR proteins function by mobilizing and stabilizing asymmetrically localized protein complexes. Curr. Biol. 14, 851-862.
    • (2004) Curr. Biol. , vol.14 , pp. 851-862
    • Cheeks, R.J.1    Canman, J.C.2    Gabriel, W.N.3    Meyer, N.4    Strome, S.5    Goldstein, B.6
  • 6
    • 0028843197 scopus 로고
    • Control of cleavage spindle orientation in Caenorhabditis elegans: The role of the genes par-2 and par-3
    • Cheng, N. N., Kirby, C. M. and Kemphues, K. J. (1995). Control of cleavage spindle orientation in Caenorhabditis elegans: the role of the genes par-2 and par-3. Genetics 139, 549-559.
    • (1995) Genetics , vol.139 , pp. 549-559
    • Cheng, N.N.1    Kirby, C.M.2    Kemphues, K.J.3
  • 7
    • 0037386142 scopus 로고    scopus 로고
    • Polarization of the C. elegans zygote proceeds via distinct establishment and maintenance phases
    • Cuenca, A. A., Schetter, A., Aceto, D., Kemphues, K. and Seydoux, G. (2003). Polarization of the C. elegans zygote proceeds via distinct establishment and maintenance phases. Development 130, 1255-1265.
    • (2003) Development , vol.130 , pp. 1255-1265
    • Cuenca, A.A.1    Schetter, A.2    Aceto, D.3    Kemphues, K.4    Seydoux, G.5
  • 8
    • 80053123895 scopus 로고    scopus 로고
    • PAR-3 oligomerization may provide an actin-independent mechanism to maintain distinct par protein domains in the early Caenorhabditis elegans embryo
    • Dawes, A. T. and Munro, E. M. (2011). PAR-3 oligomerization may provide an actin-independent mechanism to maintain distinct par protein domains in the early Caenorhabditis elegans embryo. Biophys. J. 101, 1412-1422.
    • (2011) Biophys. J. , vol.101 , pp. 1412-1422
    • Dawes, A.T.1    Munro, E.M.2
  • 9
    • 70350022781 scopus 로고    scopus 로고
    • Myosin II regulation during C. elegans embryonic elongation: LET-502/ROCK, MRCK-1 and PAK-1, three kinases with different roles
    • Gally, C., Wissler, F., Zahreddine, H., Quintin, S., Landmann, F. and Labouesse, M. (2009). Myosin II regulation during C. elegans embryonic elongation: LET-502/ROCK, MRCK-1 and PAK-1, three kinases with different roles. Development 136, 3109-3119.
    • (2009) Development , vol.136 , pp. 3109-3119
    • Gally, C.1    Wissler, F.2    Zahreddine, H.3    Quintin, S.4    Landmann, F.5    Labouesse, M.6
  • 10
    • 79956193666 scopus 로고    scopus 로고
    • PAR proteins diffuse freely across the anterior-posterior boundary in polarized C. elegans embryos
    • Goehring, N. W., Hoege, C., Grill, S. W. and Hyman, A. A. (2011a). PAR proteins diffuse freely across the anterior-posterior boundary in polarized C. elegans embryos. J. Cell Biol. 193, 583-594.
    • (2011) J. Cell Biol. , vol.193 , pp. 583-594
    • Goehring, N.W.1    Hoege, C.2    Grill, S.W.3    Hyman, A.A.4
  • 12
    • 0035799292 scopus 로고    scopus 로고
    • CDC-42 controls early cell polarity and spindle orientation in C. elegans
    • Gotta, M., Abraham, M. C. and Ahringer, J. (2001). CDC-42 controls early cell polarity and spindle orientation in C. elegans. Curr. Biol. 11, 482-488.
    • (2001) Curr. Biol. , vol.11 , pp. 482-488
    • Gotta, M.1    Abraham, M.C.2    Ahringer, J.3
  • 13
    • 31744439314 scopus 로고    scopus 로고
    • Stabilization of cell polarity by the C. elegans RING protein PAR-2
    • Hao, Y., Boyd, L. and Seydoux, G. (2006). Stabilization of cell polarity by the C. elegans RING protein PAR-2. Dev. Cell 10, 199-208.
    • (2006) Dev. Cell , vol.10 , pp. 199-208
    • Hao, Y.1    Boyd, L.2    Seydoux, G.3
  • 14
    • 77955493116 scopus 로고    scopus 로고
    • LGL can partition the cortex of one-cell Caenorhabditis elegans embryos into two domains
    • Hoege, C., Constantinescu, A. T., Schwager, A., Goehring, N. W., Kumar, P. and Hyman, A. A. (2010). LGL can partition the cortex of one-cell Caenorhabditis elegans embryos into two domains. Curr. Biol. 20, 1296-1303.
    • (2010) Curr. Biol. , vol.20 , pp. 1296-1303
    • Hoege, C.1    Constantinescu, A.T.2    Schwager, A.3    Goehring, N.W.4    Kumar, P.5    Hyman, A.A.6
  • 15
    • 0032949091 scopus 로고    scopus 로고
    • PAR-6 is a conserved PDZ domaincontaining protein that colocalizes with PAR-3 in Caenorhabditis elegans embryos
    • Hung, T. J. and Kemphues, K. J. (1999). PAR-6 is a conserved PDZ domaincontaining protein that colocalizes with PAR-3 in Caenorhabditis elegans embryos. Development 126, 127-135.
    • (1999) Development , vol.126 , pp. 127-135
    • Hung, T.J.1    Kemphues, K.J.2
  • 16
    • 51249093026 scopus 로고    scopus 로고
    • C. elegans Brat homologs regulate PAR protein-dependent polarity and asymmetric cell division
    • Hyenne, V., Desrosiers, M. and Labbé, J. C. (2008). C. elegans Brat homologs regulate PAR protein-dependent polarity and asymmetric cell division. Dev. Biol. 321, 368-378.
    • (2008) Dev. Biol. , vol.321 , pp. 368-378
    • Hyenne, V.1    Desrosiers, M.2    Labbé, J.C.3
  • 17
    • 0035799308 scopus 로고    scopus 로고
    • CDC-42 regulates PAR protein localization and function to control cellular and embryonic polarity in C. elegans
    • Kay, A. J. and Hunter, C. P. (2001). CDC-42 regulates PAR protein localization and function to control cellular and embryonic polarity in C. elegans. Curr. Biol. 11, 474-481.
    • (2001) Curr. Biol. , vol.11 , pp. 474-481
    • Kay, A.J.1    Hunter, C.P.2
  • 18
    • 0024284814 scopus 로고
    • Identification of genes required for cytoplasmic localization in early C. elegans embryos
    • Kemphues, K. J., Priess, J. R., Morton, D. G. and Cheng, N. S. (1988). Identification of genes required for cytoplasmic localization in early C. elegans embryos. Cell 52, 311-320.
    • (1988) Cell , vol.52 , pp. 311-320
    • Kemphues, K.J.1    Priess, J.R.2    Morton, D.G.3    Cheng, N.S.4
  • 19
    • 75649117062 scopus 로고    scopus 로고
    • CGEF-1 and CHIN-1 regulate CDC-42 activity during asymmetric division in the Caenorhabditis elegans embryo
    • Kumfer, K. T., Cook, S. J., Squirrell, J. M., Eliceiri, K. W., Peel, N., O'Connell, K. F. and White, J. G. (2010). CGEF-1 and CHIN-1 regulate CDC-42 activity during asymmetric division in the Caenorhabditis elegans embryo. Mol. Biol. Cell 21, 266-277.
    • (2010) Mol. Biol. Cell , vol.21 , pp. 266-277
    • Kumfer, K.T.1    Cook, S.J.2    Squirrell, J.M.3    Eliceiri, K.W.4    Peel, N.5    O'Connell, K.F.6    White, J.G.7
  • 20
    • 77649179932 scopus 로고    scopus 로고
    • Binding to PKC-3, but not to PAR-3 or to a conventional PDZ domain ligand, is required for PAR-6 function in C. elegans
    • Li, J., Kim, H., Aceto, D. G., Hung, J., Aono, S. and Kemphues, K. J. (2010). Binding to PKC-3, but not to PAR-3 or to a conventional PDZ domain ligand, is required for PAR-6 function in C. elegans. Dev. Biol. 340, 88-98.
    • (2010) Dev. Biol. , vol.340 , pp. 88-98
    • Li, J.1    Kim, H.2    Aceto, D.G.3    Hung, J.4    Aono, S.5    Kemphues, K.J.6
  • 21
    • 0028818537 scopus 로고
    • Identification and cloning of unc-119, a gene expressed in the Caenorhabditis elegans nervous system
    • Maduro, M. and Pilgrim, D. (1995). Identification and cloning of unc-119, a gene expressed in the Caenorhabditis elegans nervous system. Genetics 141, 977-988.
    • (1995) Genetics , vol.141 , pp. 977-988
    • Maduro, M.1    Pilgrim, D.2
  • 22
    • 77957364208 scopus 로고    scopus 로고
    • Anisotropies in cortical tension reveal the physical basis of polarizing cortical flows
    • Mayer, M., Depken, M., Bois, J. S., Jülicher, F. and Grill, S. W. (2010). Anisotropies in cortical tension reveal the physical basis of polarizing cortical flows. Nature 467, 617-621.
    • (2010) Nature , vol.467 , pp. 617-621
    • Mayer, M.1    Depken, M.2    Bois, J.S.3    Jülicher, F.4    Grill, S.W.5
  • 23
    • 33748202573 scopus 로고    scopus 로고
    • Sequential functioning of the ECT-2 RhoGEF, RHO-1 and CDC-42 establishes cell polarity in Caenorhabditis elegans embryos
    • Motegi, F. and Sugimoto, A. (2006). Sequential functioning of the ECT-2 RhoGEF, RHO-1 and CDC-42 establishes cell polarity in Caenorhabditis elegans embryos. Nat. Cell Biol. 8, 978-985.
    • (2006) Nat. Cell Biol. , vol.8 , pp. 978-985
    • Motegi, F.1    Sugimoto, A.2
  • 24
    • 4544316472 scopus 로고    scopus 로고
    • Cortical flows powered by asymmetrical contraction transport PAR proteins to establish and maintain anterior-posterior polarity in the early C. elegans embryo
    • Munro, E., Nance, J. and Priess, J. R. (2004). Cortical flows powered by asymmetrical contraction transport PAR proteins to establish and maintain anterior-posterior polarity in the early C. elegans embryo. Dev. Cell 7, 413-424.
    • (2004) Dev. Cell , vol.7 , pp. 413-424
    • Munro, E.1    Nance, J.2    Priess, J.R.3
  • 25
  • 26
    • 79951520024 scopus 로고    scopus 로고
    • Elaborating polarity: PAR proteins and the cytoskeleton
    • Nance, J. and Zallen, J. A. (2011). Elaborating polarity: PAR proteins and the cytoskeleton. Development 138, 799-809.
    • (2011) Development , vol.138 , pp. 799-809
    • Nance, J.1    Zallen, J.A.2
  • 27
    • 0344033629 scopus 로고    scopus 로고
    • C. elegans PAR-3 and PAR-6 are required for apicobasal asymmetries associated with cell adhesion and gastrulation
    • Nance, J., Munro, E. M. and Priess, J. R. (2003). C. elegans PAR-3 and PAR-6 are required for apicobasal asymmetries associated with cell adhesion and gastrulation. Development 130, 5339-5350.
    • (2003) Development , vol.130 , pp. 5339-5350
    • Nance, J.1    Munro, E.M.2    Priess, J.R.3
  • 28
    • 33750288512 scopus 로고    scopus 로고
    • CDC-42 and RHO-1 coordinate actomyosin contractility and PAR protein localization during polarity establishment in C. elegans embryos
    • Schonegg, S. and Hyman, A. A. (2006). CDC-42 and RHO-1 coordinate actomyosin contractility and PAR protein localization during polarity establishment in C. elegans embryos. Development 133, 3507-3516.
    • (2006) Development , vol.133 , pp. 3507-3516
    • Schonegg, S.1    Hyman, A.A.2
  • 29
    • 0035941485 scopus 로고    scopus 로고
    • Ingestion of bacterially expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans
    • Timmons, L., Court, D. L. and Fire, A. (2001). Ingestion of bacterially expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans. Gene 263, 103-112.
    • (2001) Gene , vol.263 , pp. 103-112
    • Timmons, L.1    Court, D.L.2    Fire, A.3
  • 30
    • 0029850113 scopus 로고    scopus 로고
    • par-6, a gene involved in the establishment of asymmetry in early C. elegans embryos, mediates the asymmetric localization of PAR-3
    • Watts, J. L., Etemad-Moghadam, B., Guo, S., Boyd, L., Draper, B. W., Mello, C. C., Priess, J. R. and Kemphues, K. J. (1996). par-6, a gene involved in the establishment of asymmetry in early C. elegans embryos, mediates the asymmetric localization of PAR-3. Development 122, 3133-3140.
    • (1996) Development , vol.122 , pp. 3133-3140
    • Watts, J.L.1    Etemad-Moghadam, B.2    Guo, S.3    Boyd, L.4    Draper, B.W.5    Mello, C.C.6    Priess, J.R.7    Kemphues, K.J.8
  • 31
    • 52949115363 scopus 로고    scopus 로고
    • Linking cell cycle to asymmetric division: Aurora-A phosphorylates the Par complex to regulate Numb localization
    • Wirtz-Peitz, F., Nishimura, T. and Knoblich, J. A. (2008). Linking cell cycle to asymmetric division: Aurora-A phosphorylates the Par complex to regulate Numb localization. Cell 135, 161-173.
    • (2008) Cell , vol.135 , pp. 161-173
    • Wirtz-Peitz, F.1    Nishimura, T.2    Knoblich, J.A.3


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