PDZ Domains of Par-3 as Potential Phosphoinositide Signaling Integrators

Molecular Cell

Volumn 28, Issue 5, 2007, Pages 886-898

  Wu, Hao ^a   Feng, Wei ^a   Chen, Jia ^a   Chan, Ling Nga ^a   Huang, Siyi ^a   Zhang, Mingjie ^a  

^a HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Hong Kong)

Author keywords

SIGNALING

Indexed keywords

PDZ PROTEIN; PHOSPHATIDYLINOSITIDE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEINASE ACTIVATED RECEPTOR 3;

ARTICLE; BINDING AFFINITY; CELL POLARITY; CELL TYPE; CONTROLLED STUDY; EPITHELIUM CELL; GENOME; HUMAN; HUMAN CELL; LIPID MEMBRANE; MAMMAL; NONHUMAN; PROTEIN DOMAIN; PROTEIN LIPID INTERACTION; PROTEIN PROTEIN INTERACTION;

ANIMALS; CALCIUM; CARRIER PROTEINS; CELL MEMBRANE; CELLS, CULTURED; HUMANS; IMMUNOPRECIPITATION; KIDNEY; LIPID BILAYERS; MAGNETIC RESONANCE SPECTROSCOPY; PDZ DOMAINS; PHOSPHATIDYLINOSITOLS; PROTEIN BINDING; PTEN PHOSPHOHYDROLASE; RATS; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION;

MAMMALIA; PIPS;

EID: 36749070993     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molcel.2007.10.028     Document Type: Article

References (42)

1. Benton R., and St Johnston D. Drosophila PAR-1 and 14-3-3 inhibit Bazooka/PAR-3 to establish complementary cortical domains in polarized cells. Cell 115 (2003) 691-704
2. Brunger A.T., Adams P.D., Clore G.M., DeLano W.L., Gros P., Grosse-Kunstleve R.W., Jiang J.S., Kuszewski J., Nilges M., Pannu N.S., et al. Crystallography & NMR system: a new software suite for macromolecular structure determination. Acta Crystallogr. D Biol. Crystallogr. 54 (1998) 905-921
3. Cavanagh J., Fairbrother W.J., Palmer III A.G., and Skelton N.J. Protein NMR Spectroscopy: Principles and Practice (1996), Academic Press, San Diego
4. Chen X., and Macara I.G. Par-3 controls tight junction assembly through the Rac exchange factor Tiam1. Nat. Cell Biol. 7 (2005) 262-269
5. Crowley K.S., Reinhart G.D., and Johnson A.E. The signal sequence moves through a ribosomal tunnel into a noncytoplasmic aqueous environment at the ER membrane early in translocation. Cell 73 (1993) 1101-1115
6. DiNitto J.P., Cronin T.C., and Lambright D.G. Membrane recognition and targeting by lipid-binding domains. Sci. STKE 2003 (2003) re16
7. Etemad-Moghadam B., Guo S., and Kemphues K.J. Asymmetrically distributed PAR-3 protein contributes to cell polarity and spindle alignment in early C. elegans embryos. Cell 83 (1995) 743-752
8. Etienne-Manneville S., and Hall A. Integrin-mediated activation of Cdc42 controls cell polarity in migrating astrocytes through PKCzeta. Cell 106 (2001) 489-498
9. Feng W., Shi Y., Li M., and Zhang M. Tandem PDZ repeats in glutamate receptor-interacting proteins have a novel mode of PDZ domain-mediated target binding. Nat. Struct. Biol. 10 (2003) 972-978
10. Feng W., Wu H., Chan L.N., and Zhang M. The Par-3 NTD adopts a PB1-like structure required for Par-3 oligomerization and membrane localization. EMBO J. 26 (2007) 2786-2796
11. Funamoto S., Meili R., Lee S., Parry L., and Firtel R.A. Spatial and temporal regulation of 3-phosphoinositides by PI 3-kinase and PTEN mediates chemotaxis. Cell 109 (2002) 611-623
12. Grootjans J.J., Reekmans G., Ceulemans H., and David G. Syntenin-syndecan binding requires syndecan-synteny and the co-operation of both PDZ domains of syntenin. J. Biol. Chem. 275 (2000) 19933-19941
13. Harris T.J., and Peifer M. The positioning and segregation of apical cues during epithelial polarity establishment in Drosophila. J. Cell Biol. 170 (2005) 813-823
14. Hirose T., Izumi Y., Nagashima Y., Tamai-Nagai Y., Kurihara H., Sakai T., Suzuki Y., Yamanaka T., Suzuki A., Mizuno K., and Ohno S. Involvement of ASIP/PAR-3 in the promotion of epithelial tight junction formation. J. Cell Sci. 115 (2002) 2485-2495
15. Hurd T.W., Gao L., Roh M.H., Macara I.G., and Margolis B. Direct interaction of two polarity complexes implicated in epithelial tight junction assembly. Nat. Cell Biol. 5 (2003) 137-142
16. Huynh J.R., Petronczki M., Knoblich J.A., and St Johnston D. Bazooka and PAR-6 are required with PAR-1 for the maintenance of oocyte fate in Drosophila. Curr. Biol. 11 (2001) 901-906
17. Iijima M., and Devreotes P. Tumor suppressor PTEN mediates sensing of chemoattractant gradients. Cell 109 (2002) 599-610
18. Kemphues K. PARsing embryonic polarity. Cell 101 (2000) 345-348
19. Kemphues K.J., Priess J.R., Morton D.G., and Cheng N.S. Identification of genes required for cytoplasmic localization in early C. elegans embryos. Cell 52 (1988) 311-320
20. Koradi R., Billeter M., and Wuthrich K. MOLMOL: a program for display and analysis of macromolecular structures. J. Mol. Graph. 14 (1996) 51-55
21. Lemmon M.A., and Ferguson K.M. Signal-dependent membrane targeting by pleckstrin homology (PH) domains. Biochem. J. 350 (2000) 1-18
22. Long J.F., Tochio H., Wang P., Fan J.S., Sala C., Niethammer M., Sheng M., and Zhang M. Supramodular structure and synergistic target binding of the N-terminal tandem PDZ domains of PSD-95. J. Mol. Biol. 327 (2003) 203-214
23. Long J.F., Feng W., Wang R., Chan L.N., Ip F.C., Xia J., Ip N.Y., and Zhang M. Autoinhibition of X11/Mint scaffold proteins revealed by the closed conformation of the PDZ tandem. Nat. Struct. Mol. Biol. 12 (2005) 722-728
24. Macara I.G. Par proteins: partners in polarization. Curr. Biol. 14 (2004) R160-R162
25. Mortier E., Wuytens G., Leenaerts I., Hannes F., Heung M.Y., Degeest G., David G., and Zimmermann P. Nuclear speckles and nucleoli targeting by PIP(2)-PDZ domain interactions. EMBO J. 24 (2005) 2556-2565
26. Nam S.C., and Choi K.W. Interaction of Par-6 and Crumbs complexes is essential for photoreceptor morphogenesis in Drosophila. Development 130 (2003) 4363-4372
27. Nicholls A. GRASP: Graphical Representation and Analysis of Surface Properties (1992), Columbia University, New York
28. Nishimura T., Yamaguchi T., Kato K., Yoshizawa M., Nabeshima Y., Ohno S., Hoshino M., and Kaibuchi K. PAR-6-PAR-3 mediates Cdc42-induced Rac activation through the Rac GEFs STEF/Tiam1. Nat. Cell Biol. 7 (2005) 270-277
29. Pinal N., Goberdhan D.C., Collinson L., Fujita Y., Cox I.M., Wilson C., and Pichaud F. Regulated and polarized PtdIns(3,4,5)P3 accumulation is essential for apical membrane morphogenesis in photoreceptor epithelial cells. Curr. Biol. 16 (2006) 140-149
30. Plant P.J., Fawcett J.P., Lin D.C., Holdorf A.D., Binns K., Kulkarni S., and Pawson T. A polarity complex of mPar-6 and atypical PKC binds, phosphorylates and regulates mammalian Lgl. Nat. Cell Biol. 5 (2003) 301-308
31. Sasaki A.T., Chun C., Takeda K., and Firtel R.A. Localized Ras signaling at the leading edge regulates PI3K, cell polarity, and directional cell movement. J. Cell Biol. 167 (2004) 505-518
32. Shi S.H., Jan L.Y., and Jan Y.N. Hippocampal neuronal polarity specified by spatially localized mPar3/mPar6 and PI 3-kinase activity. Cell 112 (2003) 63-75
33. Suzuki A., and Ohno S. The PAR-aPKC system: lessons in polarity. J. Cell Sci. 119 (2006) 979-987
34. Suzuki A., Yamanaka T., Hirose T., Manabe N., Mizuno K., Shimizu M., Akimoto K., Izumi Y., Ohnishi T., and Ohno S. Atypical protein kinase C is involved in the evolutionarily conserved par protein complex and plays a critical role in establishing epithelia-specific junctional structures. J. Cell Biol. 152 (2001) 1183-1196
35. Tabuse Y., Izumi Y., Piano F., Kemphues K.J., Miwa J., and Ohno S. Atypical protein kinase C cooperates with PAR-3 to establish embryonic polarity in Caenorhabditis elegans. Development 125 (1998) 3607-3614
36. Vanhaesebroeck B., Jones G.E., Allen W.E., Zicha D., Hooshmand-Rad R., Sawyer C., Wells C., Waterfield M.D., and Ridley A.J. Distinct PI(3)Ks mediate mitogenic signalling and cell migration in macrophages. Nat. Cell Biol. 1 (1999) 69-71
37. von Stein W., Ramrath A., Grimm A., Muller-Borg M., and Wodarz A. Direct association of Bazooka/PAR-3 with the lipid phosphatase PTEN reveals a link between the PAR/aPKC complex and phosphoinositide signaling. Development 132 (2005) 1675-1686
38. Wang F., Herzmark P., Weiner O.D., Srinivasan S., Servant G., and Bourne H.R. Lipid products of PI(3)Ks maintain persistent cell polarity and directed motility in neutrophils. Nat. Cell Biol. 4 (2002) 513-518
39. Yan J., Wen W., Xu W., Long J.F., Adams M.E., Froehner S.C., and Zhang M. Structure of the split PH domain and distinct lipid-binding properties of the PH-PDZ supramodule of alpha-syntrophin. EMBO J. 24 (2005) 3985-3995
40. Yu J.W., Mendrola J.M., Audhya A., Singh S., Keleti D., DeWald D.B., Murray D., Emr S.D., and Lemmon M.A. Genome-wide analysis of membrane targeting by S. cerevisiae pleckstrin homology domains. Mol. Cell 13 (2004) 677-688
41. Zhang H., and Macara I.G. The polarity protein PAR-3 and TIAM1 cooperate in dendritic spine morphogenesis. Nat. Cell Biol. 8 (2006) 227-237
42. Zimmermann P., Meerschaert K., Reekmans G., Leenaerts I., Small J.V., Vandekerckhove J., David G., and Gettemans J. PIP(2)-PDZ domain binding controls the association of syntenin with the plasma membrane. Mol. Cell 9 (2002) 1215-1225