MEX-5 and MEX-6 function to establish soma/germline asymmetry in early C. elegans embryos

Molecular Cell

Volumn 5, Issue 4, 2000, Pages 671-682

  Schubert, Charlotte M ^a,b   Lin, Rueyling ^a,b   De Vries, Corry J ^c   Plasterk, Ronald H A ^c   Priess, James R ^a,b  

^a UNIVERSITY OF WASHINGTON   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c NETHERLANDS CANCER INSTITUTE   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOPLASM PROTEIN; MESSENGER RNA; PROTEINASE ACTIVATED RECEPTOR 1; PROTEINASE ACTIVATED RECEPTOR 3;

ARTICLE; BLASTOMERE; CAENORHABDITIS ELEGANS; EMBRYOLOGY; FERTILIZATION; GENE; GERM LINE; GERMINATION; NONHUMAN; PARASITE IDENTIFICATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS INHIBITION; SOMATIC CELL; SPECIES DIFFERENTIATION;

CAENORHABDITIS ELEGANS; RICKETTSIA SP. PAR;

EID: 0033634970     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(00)80246-4     Document Type: Article

References (49)

1. The 30-kD subunit of mammalian cleavage and polyadenylation specificity factor and its yeast homolog are RNA-binding zinc finger proteins
2. Mammalian homologues of C. elegans PAR-1 are asymmetrically localized in epithelial cells and may influence their polarity
3. Cell polarity in the early Caenorhabditis elegans embryo
4. Skn-1, a maternally expressed gene required to specify the fate of ventral blastomeres in the early C. elegans embryo
5. The maternal gene skn-1 encodes a protein that is distributed unequally in early C. elegans embryos
6. The maternal par genes and the segregation of cell fate specification activities in early Caenorhabditis elegans embryos
7. PAR-2 is asymmetrically distributed and promotes association of P granules and PAR-1 with the cortex in C. elegans embryos
8. The genetics of Caenorhabditis elegans
9. Feedback inhibition of macrophage tumor necrosis factor-alpha production by tristetraprolin
10. Genes required for GLP-1 asymmetry in the early Caenorhabditis elegans embryo
11. MEX-3 is a KH domain protein that regulates blastomere identity in early C. elegans embryos
12. A growth factor-inducible nuclear protein with a novel cysteine/histidine repetitive sequence
13. Asymmetrically distributed PAR-3 protein contributes to cell polarity and spindle alignment in early C. elegans embryos
14. Translational control of maternal glp-1 mRNA establishes an asymmetry in the C. elegans embryo
15. Components of an SCF ubiquitin ligase localize to the centrosome and regulate the centrosome duplication cycle
16. The C. elegans MEX-1 protein is present in germline blastomeres and is a P granule component
17. Par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed
18. PAR-6 is a conserved PDZ domain-containing protein that colocalizes with PAR-3 Caenorhabditis elegans embryos
19. Spatial and temporal controls target pal-1 blastomere-specification activity to a single blastomere lineage in C. elegans embryos
20. An atypical PKC directly associates and colocalizes at the epithelial tight junction with ASIP, a mammalian homologue of Caenorhabditis elegans polarity protein PAR-3
21. Reverse genetics by chemical mutagenesis in Caenorhabditis elegans
22. The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase
23. Identification of genes required for cytoplasmic localization in early C. elegans embryos
24. Control of spindle orientation in Drosophila by the Par-3-related PDZ-domain protein Bazooka
25. Rapid insulin-stimulated accumulation of an mRNA encoding a proline-rich region
26. Evidence that tristetraprolin binds to AU-rich elements and promotes the deadenylation and destabilization of tumor necrosis factor alpha mRNA
27. Pop-1 encodes an HMG box protein required for the specification of a mesoderm precursor in early C. elegans embryos
28. RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination
29. Efficient gene transfer in C. elegans: Extrachromosomal maintenance and integration of transforming sequences
30. The pie-1 and mex-1 genes and maternal control of blastomere identity in early C. elegans embryos
31. The PIE-1 protein and germline specification in C. elegans embryos
32. Onset of C. elegans gastrulation is blocked by inhibition of embryonic transcription with an RNA polymerase antisense RNA
33. The glp-1 locus and cellular interactions in early C. elegans embryos
34. Wnt signaling and an APC-related gene specify endoderm in early C. elegans embryos
35. Early patterning of the C. elegans embryo
36. Reversal of cellular polarity and early cell-cell interaction in the embryos of Caenorhabditis elegans
37. Bazooka recruits Inscuteable to orient asymmetric cell divisions in Drosophila neuroblasts
38. Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34
39. Soma-germline asymmetry in the distributions of embryonic RNAs in Caenorhabditis elegans
40. Repression of gene expression in the embryonic germ lineage of C. elegans
41. Immunofluorescence visualization of germ-line-specific cytoplasmic granules in embryos, larvae, and adults of Caenorhabditis elegans
42. Pos-1 encodes a cytoplasmic zinc-finger protein essential for germline specification in C. elegans
43. Atypical protein kinase C cooperates with PAR-3 to establish embryonic polarity in Caenorhabiditis elegans
44. Genetic requirements for PIE-1 localization and inhibition of gene expression in the embryonic germ lineage of Caenorhabditis elegans
45. Nucleotide sequence of a cDNA encoding TIS11, a message induced in Swiss 3T3 cells by the tumor promoter tetradecanoyl phorbol acetate
46. The RING finger of c-Cbl mediates desensitization of the epidermal growth factor receptor
47. Identification of multiple cell adhesion receptors for collagen and fibronectin in human fibrosarcoma cells possessing unique alpha and common beta subunits
48. Bazooka provides an apical cue for Inscuteable localization in Drosophila neuroblasts
49. The splicing factor U2AF35 mediates critical protein-protein interactions in constitutive and enhancer-dependent splicing