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Volumn 24, Issue 18, 2013, Pages 2795-2806

G protein-coupled receptor kinase 2 (GRK2) is localized to centrosomes and mediates epidermal growth factor-promoted centrosomal separation

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR; G PROTEIN COUPLED RECEPTOR KINASE 2; MAMMALIAN STE20 LIKE KINASE 2; NEK2A; PROTEIN KINASE; UNCLASSIFIED DRUG;

EID: 84884485850     PISSN: 10591524     EISSN: 19394586     Source Type: Journal    
DOI: 10.1091/mbc.E13-01-0013     Document Type: Article
Times cited : (20)

References (70)
  • 1
    • 80051483020 scopus 로고    scopus 로고
    • G protein-coupled receptor kinase 5 phosphorylation of hip regulates internalization of the chemokine receptor CXCR4
    • Barker BL, Benovic JL (2012). G protein-coupled receptor kinase 5 phosphorylation of hip regulates internalization of the chemokine receptor CXCR4. Biochemistry 50, 6933-6941.
    • (2012) Biochemistry , vol.50 , pp. 6933-6941
    • Barker, B.L.1    Benovic, J.L.2
  • 2
    • 70349210074 scopus 로고    scopus 로고
    • Beta-arrestin1 phosphorylation by GRK5 regulates G protein-independent 5-HT4 receptor signalling
    • Barthet G et al. (2009). Beta-arrestin1 phosphorylation by GRK5 regulates G protein-independent 5-HT4 receptor signalling. EMBO J 28, 2706-2718.
    • (2009) EMBO J , vol.28 , pp. 2706-2718
    • Barthet, G.1
  • 3
    • 44649117902 scopus 로고    scopus 로고
    • Centrosome Amplification Can Initiate Tumorigenesis in Flies
    • DOI 10.1016/j.cell.2008.05.039, PII S0092867408007010
    • Basto R, Brunk K, Vinadogrova T, Peel N, Franz A, Khodjakov A, Raff JW (2008). Centrosome amplification can initiate tumorigenesis in flies. Cell 133, 1032-1042. (Pubitemid 351787756)
    • (2008) Cell , vol.133 , Issue.6 , pp. 1032-1042
    • Basto, R.1    Brunk, K.2    Vinadogrova, T.3    Peel, N.4    Franz, A.5    Khodjakov, A.6    Raff, J.W.7
  • 4
    • 79952437118 scopus 로고    scopus 로고
    • Systematic discovery of ectopic pregnancy serum biomarkers using 3-D protein profiling coupled with label-free quantitation
    • Beer LA, Tang HY, Sriswasdi S, Barnhart KT, Speicher DW (2011). Systematic discovery of ectopic pregnancy serum biomarkers using 3-D protein profiling coupled with label-free quantitation. J Proteome Res 10, 1126-1138.
    • (2011) J Proteome Res , vol.10 , pp. 1126-1138
    • Beer, L.A.1    Tang, H.Y.2    Sriswasdi, S.3    Barnhart, K.T.4    Speicher, D.W.5
  • 5
    • 34249336078 scopus 로고    scopus 로고
    • Centrosome biogenesis and function: Centrosomics brings new understanding
    • DOI 10.1038/nrm2180, PII NRM2180
    • Bettencourt-Dias M, Glover DM (2007). Centrosome biogenesis and function: centrosomics brings new understanding. Nat Rev Mol Cell Biol 8, 451-463. (Pubitemid 46809152)
    • (2007) Nature Reviews Molecular Cell Biology , vol.8 , Issue.6 , pp. 451-463
    • Bettencourt-Dias, M.1    Glover, D.M.2
  • 6
    • 0032614931 scopus 로고    scopus 로고
    • Studying the composition and function of centrosomes in vertebrates
    • Bornens M, Moudjou M (1999). Studying the composition and function of centrosomes in vertebrates. Methods Cell Biol 61, 13-34.
    • (1999) Methods Cell Biol , vol.61 , pp. 13-34
    • Bornens, M.1    Moudjou, M.2
  • 7
    • 84859243184 scopus 로고    scopus 로고
    • The nuclear epidermal growth factor receptor signaling network and its role in cancer
    • Brand TM, Iida M, Li C, Wheeler DL (2011). The nuclear epidermal growth factor receptor signaling network and its role in cancer. Discov Med 12, 419-432.
    • (2011) Discov Med , vol.12 , pp. 419-432
    • Brand, T.M.1    Iida, M.2    Li, C.3    Wheeler, D.L.4
  • 8
    • 77951230331 scopus 로고    scopus 로고
    • Site-specific phosphorylation of CXCR4 is dynamically regulated by multiple kinases and results in differential modulation of CXCR4 signaling
    • Busillo JM, Armando S, Sengupta R, Meucci O, Bouvier M, Benovic JL (2010). Site-specific phosphorylation of CXCR4 is dynamically regulated by multiple kinases and results in differential modulation of CXCR4 signaling. J Biol Chem 285, 7805-7817.
    • (2010) J Biol Chem , vol.285 , pp. 7805-7817
    • Busillo, J.M.1    Armando, S.2    Sengupta, R.3    Meucci, O.4    Bouvier, M.5    Benovic, J.L.6
  • 9
    • 80052279155 scopus 로고    scopus 로고
    • Reduced expression of G protein-coupled receptor kinases in schizophrenia but not in schizoaffective disorder
    • Bychkov ER, Ahmed MR, Gurevich VV, Benovic JL, Gurevich EV (2011). Reduced expression of G protein-coupled receptor kinases in schizophrenia but not in schizoaffective disorder. Neurobiol Dis 44, 248-258.
    • (2011) Neurobiol Dis , vol.44 , pp. 248-258
    • Bychkov, E.R.1    Ahmed, M.R.2    Gurevich, V.V.3    Benovic, J.L.4    Gurevich, E.V.5
  • 10
    • 38949138075 scopus 로고    scopus 로고
    • Arrestins and two receptor kinases are upregulated in Parkinson's disease with dementia
    • DOI 10.1016/j.neurobiolaging.2006.10.012, PII S0197458006003897
    • Bychkov ER, Gurevich VV, Joyce JN, Benovic JL, Gurevich EV (2008). Arrestins and two receptor kinases are upregulated in Parkinson's disease with dementia. Neurobiol Aging 29, 379-396. (Pubitemid 351215580)
    • (2008) Neurobiology of Aging , vol.29 , Issue.3 , pp. 379-396
    • Bychkov, E.R.1    Gurevich, V.V.2    Joyce, J.N.3    Benovic, J.L.4    Gurevich, E.V.5
  • 11
    • 21844467495 scopus 로고    scopus 로고
    • G protein-coupled receptor kinase 2-mediated phosphorylation of Ezrin is required for G protein-coupled receptor-dependent reorganization of the actin cytoskeleton
    • DOI 10.1091/mbc.E04-10-0877
    • Cant SH, Pitcher JA (2005). G protein-coupled receptor kinase 2-mediated phosphorylation of ezrin is required for G protein-coupled receptor-dependent reorganization of the actin cytoskeleton. Mol Biol Cell 16, 3088-3099. (Pubitemid 40962582)
    • (2005) Molecular Biology of the Cell , vol.16 , Issue.7 , pp. 3088-3099
    • Cant, S.H.1    Pitcher, J.A.2
  • 12
    • 0032493759 scopus 로고    scopus 로고
    • Binding and phosphorylation of tubulin by G protein-coupled receptor kinases
    • DOI 10.1074/jbc.273.32.20308
    • Carman CV, Som T, Kim CM, Benovic JL (1998). Binding and phosphorylation of tubulin by G protein-coupled receptor kinases. J Biol Chem 273, 20308-20316. (Pubitemid 28377594)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.32 , pp. 20308-20316
    • Carman, C.V.1    Som, T.2    Kim, C.M.3    Benovic, J.L.4
  • 13
    • 77951219148 scopus 로고    scopus 로고
    • G-protein-coupled receptor kinase 5 phosphorylates p53 and inhibits DNA damage-induced apoptosis
    • Chen X, Zhu H, Yuan M, Fu J, Zhou Y, Ma L (2010). G-protein-coupled receptor kinase 5 phosphorylates p53 and inhibits DNA damage-induced apoptosis. J Biol Chem 285, 12823-12830.
    • (2010) J Biol Chem , vol.285 , pp. 12823-12830
    • Chen, X.1    Zhu, H.2    Yuan, M.3    Fu, J.4    Zhou, Y.5    Ma, L.6
  • 14
    • 51349094203 scopus 로고    scopus 로고
    • EGF transregulates opioid receptors through EGFR-mediated GRK2 phosphorylation and activation
    • Chen Y, Long H, Wu Z, Jiang X, Ma L (2008). EGF transregulates opioid receptors through EGFR-mediated GRK2 phosphorylation and activation. Mol Biol Cell 19, 2973-2983.
    • (2008) Mol Biol Cell , vol.19 , pp. 2973-2983
    • Chen, Y.1    Long, H.2    Wu, Z.3    Jiang, X.4    Ma, L.5
  • 15
    • 34447500683 scopus 로고    scopus 로고
    • iα proteins in the centrosomes and at the midbody: Implication for their role in cell division
    • DOI 10.1083/jcb.200604114
    • Cho H, Kehrl JH (2007). Localization of Gi proteins in the centrosomes and at the midbody: implication for their role in cell division. J Cell Biol 178, 245-255. (Pubitemid 47076461)
    • (2007) Journal of Cell Biology , vol.178 , Issue.2 , pp. 245-255
    • Cho, H.1    Kehrl, J.H.2
  • 16
    • 0038485597 scopus 로고    scopus 로고
    • Regulation of mammalian STE20-like kinase 2 (MST2) by protein phosphorylation/dephosphorylation and proteolysis
    • DOI 10.1074/jbc.M211085200
    • Deng Y, Pang A, Wang JH (2003). Regulation of mammalian STE20-like kinase 2 (MST2) by protein phosphorylation/dephosphorylation and proteolysis. J Biol Chem 278, 11760-11767. (Pubitemid 36800144)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.14 , pp. 11760-11767
    • Deng, Y.1    Pang, A.2    Wang, J.H.3
  • 19
    • 79960095377 scopus 로고    scopus 로고
    • Aggregatibacter actinomycetemcomitans leukotoxin is post-translationally modified by addition of either saturated or hydroxylated fatty acyl chains
    • Fong KP, Tang HY, Brown AC, Kieba IR, Speicher DW, Boesze-Battaglia K, Lally ET (2011). Aggregatibacter actinomycetemcomitans leukotoxin is post-translationally modified by addition of either saturated or hydroxylated fatty acyl chains. Mol Oral Microbiol 26, 262-276.
    • (2011) Mol Oral Microbiol , vol.26 , pp. 262-276
    • Fong, K.P.1    Tang, H.Y.2    Brown, A.C.3    Kieba, I.R.4    Speicher, D.W.5    Boesze-Battaglia, K.6    Lally, E.T.7
  • 20
    • 0037073735 scopus 로고    scopus 로고
    • Phosphorylation of the platelet-derived growth factor receptor-β and epidermal growth factor receptor by G protein-coupled receptor kinase-2. Mechanisms for selectivity of desensitization
    • DOI 10.1074/jbc.M204431200
    • Freedman NJ, Kim LK, Murray JP, Exum ST, Brian L, Wu JH, Peppel K (2002). Phosphorylation of the platelet-derived growth factor receptor-beta and epidermal growth factor receptor by G protein-coupled receptor kinase-2. Mechanisms for selectivity of desensitization. J Biol Chem 277, 48261-48269. (Pubitemid 35470778)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.50 , pp. 48261-48269
    • Freedman, N.J.1    Kim, L.K.2    Murray, J.P.3    Exum, S.T.4    Brian, L.5    Wu, J.-H.6    Peppel, K.7
  • 22
    • 67649467032 scopus 로고    scopus 로고
    • A mechanism linking extra centrosomes to chromosomal instability
    • Ganem NJ, Godinho SA, Pellman D (2009). A mechanism linking extra centrosomes to chromosomal instability. Nature 460, 278-282.
    • (2009) Nature , vol.460 , pp. 278-282
    • Ganem, N.J.1    Godinho, S.A.2    Pellman, D.3
  • 23
    • 77956177387 scopus 로고    scopus 로고
    • Reduced platelet G protein-coupled receptor kinase 2 in major depressive disorder: Antidepressant treatment-induced upregulation of GRK2 protein discriminates between responder and non-responder patients
    • Garcia-Sevilla JA, Alvaro-Bartolome M, Diez-Alarcia R, Ramos-Miguel A, Puigdemont D, Perez V, Alvarez E, Meana JJ (2010). Reduced platelet G protein-coupled receptor kinase 2 in major depressive disorder: antidepressant treatment-induced upregulation of GRK2 protein discriminates between responder and non-responder patients. Eur Neuropsychopharmacol 20, 721-730.
    • (2010) Eur Neuropsychopharmacol , vol.20 , pp. 721-730
    • Garcia-Sevilla, J.A.1    Alvaro-Bartolome, M.2    Diez-Alarcia, R.3    Ramos-Miguel, A.4    Puigdemont, D.5    Perez, V.6    Alvarez, E.7    Meana, J.J.8
  • 24
    • 60549113475 scopus 로고    scopus 로고
    • The sphingosine 1-phosphate receptor 5 and sphingosine kinases 1 and 2 are localised in centrosomes: Possible role in regulating cell division
    • Gillies L, Lee SC, Long JS, Ktistakis N, Pyne NJ, Pyne S (2009). The sphingosine 1-phosphate receptor 5 and sphingosine kinases 1 and 2 are localised in centrosomes: possible role in regulating cell division. Cell Signal 21, 675-684.
    • (2009) Cell Signal , vol.21 , pp. 675-684
    • Gillies, L.1    Lee, S.C.2    Long, J.S.3    Ktistakis, N.4    Pyne, N.J.5    Pyne, S.6
  • 26
    • 83555168220 scopus 로고    scopus 로고
    • G protein-coupled receptor kinases: More than just kinases and not only for GPCRs
    • Gurevich EV, Tesmer JJ, Mushegian A, Gurevich VV (2012). G protein-coupled receptor kinases: more than just kinases and not only for GPCRs. Pharmacol Ther 133, 40-69.
    • (2012) Pharmacol Ther , vol.133 , pp. 40-69
    • Gurevich, E.V.1    Tesmer, J.J.2    Mushegian, A.3    Gurevich, V.V.4
  • 27
    • 0033588029 scopus 로고    scopus 로고
    • G protein-coupled receptor kinase 6A phosphorylates the Na+/H+ exchanger regulator factor via a PDZ domain-mediated interaction
    • Hall RA, Spurney RF, Premont RT, Rahman N, Blitzer JT, Pitcher JA, Lefkowitz RJ (1999). G protein-coupled receptor kinase 6A phosphorylates the Na+/H+ exchanger regulator factor via a PDZ domain-mediated interaction. J Biol Chem 274, 24328-24334.
    • (1999) J Biol Chem , vol.274 , pp. 24328-24334
    • Hall, R.A.1    Spurney, R.F.2    Premont, R.T.3    Rahman, N.4    Blitzer, J.T.5    Pitcher, J.A.6    Lefkowitz, R.J.7
  • 28
    • 2342492317 scopus 로고    scopus 로고
    • Review of epidermal growth factor receptor biology
    • DOI 10.1016/j.ijrobp.2003.11.041, PII S0360301604003311
    • Herbst RS (2004). Review of epidermal growth factor receptor biology. Int J Radiat Oncol Biol Phys 59, 21-26. (Pubitemid 38610223)
    • (2004) International Journal of Radiation Oncology Biology Physics , vol.59 , Issue.SUPPL. , pp. 21-26
    • Herbst, R.S.1
  • 29
    • 80053355585 scopus 로고    scopus 로고
    • G protein-coupled receptor kinases in normal and failing myocardium
    • Huang ZM, Gold JI, Koch WJ (2012). G protein-coupled receptor kinases in normal and failing myocardium. Front Biosci 17, 3047-3060.
    • (2012) Front Biosci , vol.17 , pp. 3047-3060
    • Huang, Z.M.1    Gold, J.I.2    Koch, W.J.3
  • 30
    • 8644290071 scopus 로고    scopus 로고
    • G protein-coupled receptor kinase 5 contains a DNA-binding nuclear localization sequence
    • DOI 10.1128/MCB.24.23.10169-10179.2004
    • Johnson LR, Scott MG, Pitcher JA (2004). G protein-coupled receptor kinase 5 contains a DNA-binding nuclear localization sequence. Mol Cell Biol 24, 10169-10179. (Pubitemid 39507857)
    • (2004) Molecular and Cellular Biology , vol.24 , Issue.23 , pp. 10169-10179
    • Johnson, L.R.1    Scott, M.G.H.2    Pitcher, J.A.3
  • 31
    • 77949718255 scopus 로고    scopus 로고
    • Regulation of proapoptotic mammalian ste20-like kinase MST2 by the IGF1-Akt pathway
    • Kim D, Shu S, Coppola MD, Kaneko S, Yuan ZQ, Cheng JQ (2010). Regulation of proapoptotic mammalian ste20-like kinase MST2 by the IGF1-Akt pathway. PLoS One 5, e9616.
    • (2010) PLoS One , vol.5
    • Kim, D.1    Shu, S.2    Coppola, M.D.3    Kaneko, S.4    Yuan, Z.Q.5    Cheng, J.Q.6
  • 32
    • 83555164622 scopus 로고    scopus 로고
    • G-protein coupled receptor kinase 5 regulates prostate tumor growth
    • Kim JI, Chakraborty P, Wang Z, Daaka Y (2012). G-protein coupled receptor kinase 5 regulates prostate tumor growth. J Urol 187, 322-329.
    • (2012) J Urol , vol.187 , pp. 322-329
    • Kim, J.I.1    Chakraborty, P.2    Wang, Z.3    Daaka, Y.4
  • 34
    • 0028089039 scopus 로고
    • Expression, purification, and characterization of the G protein-coupled receptor kinase GRK5
    • Kunapuli P, Onorato JJ, Hosey MM, Benovic JL (1994). Expression, purification, and characterization of the G protein-coupled receptor kinase GRK5. J Biol Chem 269, 1099-1105. (Pubitemid 24032491)
    • (1994) Journal of Biological Chemistry , vol.269 , Issue.2 , pp. 1099-1105
    • Kunapuli, P.1    Onorato, J.J.2    Hosey, M.M.3    Benovic, J.L.4
  • 35
    • 0035379556 scopus 로고    scopus 로고
    • MST, a physiological caspase substrate, highly sensitizes apoptosis both upstream and downstream of caspase activation
    • Lee KK, Ohyama T, Yajima N, Tsubuki S, Yonehara S (2001). MST, a physiological caspase substrate, highly sensitizes apoptosis both upstream and downstream of caspase activation. J Biol Chem 276, 19276-19285.
    • (2001) J Biol Chem , vol.276 , pp. 19276-19285
    • Lee, K.K.1    Ohyama, T.2    Yajima, N.3    Tsubuki, S.4    Yonehara, S.5
  • 36
    • 0033917218 scopus 로고    scopus 로고
    • Epidermal growth factor receptor signal transactivation
    • Leserer M, Gschwind A, Ullrich A (2000). Epidermal growth factor receptor signal transactivation. IUBMB Life 49, 405-409. (Pubitemid 30436175)
    • (2000) IUBMB Life , vol.49 , Issue.5 , pp. 405-409
    • Leserer, M.1    Gschwind, A.2    Ullrich, A.3
  • 37
    • 0025742855 scopus 로고
    • Role of acidic amino acids in peptide substrates of the beta-adrenergic receptor kinase and rhodopsin kinase
    • Onorato J, Palczewski K, Regan JW, Caron MG, Lefkowitz RJ, Benovic JL (1991). Role of acidic amino acids in peptide substrates of the beta-adrenergic receptor kinase and rhodopsin kinase. Biochemistry 30, 5118-5125.
    • (1991) Biochemistry , vol.30 , pp. 5118-5125
    • Onorato, J.1    Palczewski, K.2    Regan, J.W.3    Caron, M.G.4    Lefkowitz, R.J.5    Benovic, J.L.6
  • 39
    • 79960161183 scopus 로고    scopus 로고
    • Plk1 controls the Nek2A-PP1gamma antagonism in centrosome disjunction
    • Mardin BR, Agircan FG, Lange C, Schiebel E (2011). Plk1 controls the Nek2A-PP1gamma antagonism in centrosome disjunction. Curr Biol 21, 1145-1151.
    • (2011) Curr Biol , vol.21 , pp. 1145-1151
    • Mardin, B.R.1    Agircan, F.G.2    Lange, C.3    Schiebel, E.4
  • 40
    • 84860272984 scopus 로고    scopus 로고
    • Breaking the ties that bind: New advances in centrosome biology
    • Mardin BR, Schiebel E (2012). Breaking the ties that bind: new advances in centrosome biology. J Cell Biol 197, 11-18.
    • (2012) J Cell Biol , vol.197 , pp. 11-18
    • Mardin, B.R.1    Schiebel, E.2
  • 43
    • 34748812613 scopus 로고    scopus 로고
    • RASSF1A Elicits Apoptosis through an MST2 Pathway Directing Proapoptotic Transcription by the p73 Tumor Suppressor Protein
    • DOI 10.1016/j.molcel.2007.08.008, PII S1097276507005515
    • Matallanas D, Romano D, Yee K, Meissl K, Kucerova L, Piazzolla D, Baccarini M, Vass JK, Kolch W, O'Neill E (2007). RASSF1A elicits apoptosis through an MAST2 pathway directing proapoptotic transcription by the p73 tumor suppressor protein. Mol Cell 27, 962-975. (Pubitemid 47495894)
    • (2007) Molecular Cell , vol.27 , Issue.6 , pp. 962-975
    • Matallanas, D.1    Romano, D.2    Yee, K.3    Meissl, K.4    Kucerova, L.5    Piazzolla, D.6    Baccarini, M.7    Vass, J.K.8    Kolch, W.9    O'Neill, E.10
  • 44
    • 55249127104 scopus 로고    scopus 로고
    • Expression of G protein-coupled receptor kinase 4 is associated with breast cancer tumourigenesis
    • Matsubayashi J et al. (2008). Expression of G protein-coupled receptor kinase 4 is associated with breast cancer tumourigenesis. J Pathol 216, 317-327.
    • (2008) J Pathol , vol.216 , pp. 317-327
    • Matsubayashi, J.1
  • 45
    • 0036324072 scopus 로고    scopus 로고
    • Expression and activity of G protein-coupled receptor kinases in differentiated thyroid carcinoma
    • DOI 10.1210/jc.87.7.3279
    • Metaye T, Menet E, Guilhot J, Kraimps JL (2002). Expression and activity of g protein-coupled receptor kinases in differentiated thyroid carcinoma. J Clin Endocrinol Metab 87, 3279-3286. (Pubitemid 34816377)
    • (2002) Journal of Clinical Endocrinology and Metabolism , vol.87 , Issue.7 , pp. 3279-3286
    • Metaye, T.1    Menet, E.2    Guilhot, J.3    Kraimps, J.-L.4
  • 46
    • 84857482492 scopus 로고    scopus 로고
    • G Protein-coupled receptor kinase 5 is localized to centrosomes and regulates cell cycle progression
    • Michal AM, So CH, Beeharry N, Shankar H, Mashayekhi R, Yen TJ, Benovic JL (2012). G Protein-coupled receptor kinase 5 is localized to centrosomes and regulates cell cycle progression. J Biol Chem 287, 6928-6940.
    • (2012) J Biol Chem , vol.287 , pp. 6928-6940
    • Michal, A.M.1    So, C.H.2    Beeharry, N.3    Shankar, H.4    Mashayekhi, R.5    Yen, T.J.6    Benovic, J.L.7
  • 47
    • 33947314576 scopus 로고    scopus 로고
    • Regulation of receptor trafficking by GRKs and arrestins
    • DOI 10.1146/annurev.physiol.69.022405.154712
    • Moore CA, Milano SK, Benovic JL (2007). Regulation of receptor trafficking by GRKs and arrestins. Annu Rev Physiol 69, 451-482. (Pubitemid 46457651)
    • (2007) Annual Review of Physiology , vol.69 , pp. 451-482
    • Moore, C.A.C.1    Milano, S.K.2    Benovic, J.L.3
  • 48
    • 33845960758 scopus 로고    scopus 로고
    • Arrestin-2 and G protein-coupled receptor kinase 5 interact with NFκB1 p105 and negatively regulate lipopolysaccharide-stimulated ERK1/2 activation in macrophages
    • DOI 10.1074/jbc.M605376200
    • Parameswaran N, Pao CS, Leonhard KS, Kang DS, Kratz M, Ley SC, Benovic JL (2006). Arrestin-2 and G protein-coupled receptor kinase 5 interact with NFkappaB1 p105 and negatively regulate lipopolysaccharide-stimulated ERK1/2 activation in macrophages. J Biol Chem 281, 34159-34170. (Pubitemid 46036624)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.45 , pp. 34159-34170
    • Parameswaran, N.1    Pao, C.S.2    Leonhard, K.S.3    Dong, S.K.4    Kratz, M.5    Ley, S.C.6    Benovic, J.L.7
  • 49
    • 72449146904 scopus 로고    scopus 로고
    • G-protein-coupled-receptor kinases mediate TNFalpha-induced NFkappaB signalling via direct interaction with and phosphorylation of IkappaBalpha
    • Patial S, Luo J, Porter KJ, Benovic JL, Parameswaran N (2009). G-protein-coupled-receptor kinases mediate TNFalpha-induced NFkappaB signalling via direct interaction with and phosphorylation of IkappaBalpha. Biochem J 425, 169-178.
    • (2009) Biochem J , vol.425 , pp. 169-178
    • Patial, S.1    Luo, J.2    Porter, K.J.3    Benovic, J.L.4    Parameswaran, N.5
  • 50
    • 75749118972 scopus 로고    scopus 로고
    • G protein-coupled receptor kinase 2 (GRK2) modulation and cell cycle progression
    • Penela P, Rivas V, Salcedo A, Mayor F Jr (2010). G protein-coupled receptor kinase 2 (GRK2) modulation and cell cycle progression. Proc Natl Acad Sci USA 107, 1118-1123.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 1118-1123
    • Penela, P.1    Rivas, V.2    Salcedo, A.3    Mayor Jr., F.4
  • 51
    • 33750218229 scopus 로고    scopus 로고
    • Phosphorylation of p38 by GRK2 at the Docking Groove Unveils a Novel Mechanism for Inactivating p38MAPK
    • DOI 10.1016/j.cub.2006.08.083, PII S0960982206021518
    • Peregrin S, Jurado-Pueyo M, Campos PM, Sanz-Moreno V, Ruiz-Gomez A, Crespo P, Mayor F Jr, Murga C (2006). Phosphorylation of p38 by GRK2 at the docking groove unveils a novel mechanism for inactivating p38MAPK. Curr Biol 16, 2042-2047. (Pubitemid 44604449)
    • (2006) Current Biology , vol.16 , Issue.20 , pp. 2042-2047
    • Peregrin, S.1    Jurado-Pueyo, M.2    Campos, P.M.3    Sanz-Moreno, V.4    Ruiz-Gomez, A.5    Crespo, P.6    Mayor Jr., F.7    Murga, C.8
  • 53
    • 0034714204 scopus 로고    scopus 로고
    • Synucleins are a novel class of substrates for G protein-coupled receptor kinases
    • Pronin AN, Morris AJ, Surguchov A, Benovic JL (2000). Synucleins are a novel class of substrates for G protein-coupled receptor kinases. J Biol Chem 275, 26515-26522.
    • (2000) J Biol Chem , vol.275 , pp. 26515-26522
    • Pronin, A.N.1    Morris, A.J.2    Surguchov, A.3    Benovic, J.L.4
  • 54
    • 0030800966 scopus 로고    scopus 로고
    • Regulation of G protein-coupled receptor kinases by calmodulin and localization of the calmodulin binding domain
    • DOI 10.1074/jbc.272.29.18273
    • Pronin AN, Satpaev DK, Slepak VZ, Benovic JL (1997). Regulation of G protein-coupled receptor kinases by calmodulin and localization of the calmodulin binding domain. J Biol Chem 272, 18273-18280. (Pubitemid 27306417)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.29 , pp. 18273-18280
    • Pronin, A.N.1    Satpaev, D.K.2    Slepak, V.Z.3    Benovic, J.L.4
  • 55
    • 76249097011 scopus 로고    scopus 로고
    • Proapoptotic kinase MST2 coordinates signaling crosstalk between RASSF1A, Raf-1 and Akt
    • Romano D, Matallanas D, Weitsman G, Preisinger C, Ng T, Kolch W (2010). Proapoptotic kinase MST2 coordinates signaling crosstalk between RASSF1A, Raf-1 and Akt. Cancer Res 70, 1195-1203.
    • (2010) Cancer Res , vol.70 , pp. 1195-1203
    • Romano, D.1    Matallanas, D.2    Weitsman, G.3    Preisinger, C.4    Ng, T.5    Kolch, W.6
  • 56
  • 57
    • 0033607513 scopus 로고    scopus 로고
    • Agonist-dependent phosphorylation of the G protein-coupled receptor kinase 2 (GRK2) by Src tyrosine kfinase
    • Sarnago S, Elorza A, Mayor F Jr (1999). Agonist-dependent phosphorylation of G protein-coupled receptor kinase 2 (GRK2) by Src tyrosine kinase. J Biol Chem 274, 34411-34416. (Pubitemid 129511786)
    • (1999) Journal of Biological Chemistry , vol.274 , Issue.48 , pp. 34411-34416
    • Sarnago, S.1    Elorza, A.2    Mayor Jr., F.3
  • 58
    • 77950897527 scopus 로고    scopus 로고
    • Non-visual arrestins are constitutively associated with the centrosome and regulate centrosome function
    • Shankar H, Michal A, Kern RC, Kang DS, Gurevich VV, Benovic JL (2010). Non-visual arrestins are constitutively associated with the centrosome and regulate centrosome function. J Biol Chem 285, 8316-8329.
    • (2010) J Biol Chem , vol.285 , pp. 8316-8329
    • Shankar, H.1    Michal, A.2    Kern, R.C.3    Kang, D.S.4    Gurevich, V.V.5    Benovic, J.L.6
  • 59
    • 0020313101 scopus 로고
    • Epidermal growth factor induces rapid centrosomal separation in HeLa and 3T3 cells
    • DOI 10.1083/jcb.93.2.507
    • Sherline P, Mascardo RN (1982a). Epidermal growth factor induces rapid centrosomal separation in HeLa and 3T3 cells. J Cell Biol 93, 507-512. (Pubitemid 12014140)
    • (1982) Journal of Cell Biology , vol.93 , Issue.2 , pp. 507-512
    • Sherline, P.1    Mascardo, R.N.2
  • 60
    • 0020394538 scopus 로고
    • Epidermal growth factor-induced centrosomal separation: Mechanism and relationship to mitogenesis
    • DOI 10.1083/jcb.95.1.316
    • Sherline P, Mascardo R (1982b). Epidermal growth factor-induced centrosomal separation: mechanism and relationship to mitogenesis. J Cell Biol 95, 316-322. (Pubitemid 13197102)
    • (1982) Journal of Cell Biology , vol.95 , Issue.1 , pp. 316-322
    • Sherline, P.1    Mascardo, R.2
  • 61
    • 0021142483 scopus 로고
    • Co-ordinate control of centrosomal separation and DNA synthesis by growth regulators
    • Sherline P, Mascardo RN (1984). Co-ordinate control of centrosomal separation and DNA synthesis by growth regulators. Exp Cell Res 153, 109-120. (Pubitemid 14088408)
    • (1984) Experimental Cell Research , vol.153 , Issue.1 , pp. 109-120
    • Sherline, P.1    Mascardo, R.N.2
  • 62
    • 84856426337 scopus 로고    scopus 로고
    • Timing of centrosome separation is important for accurate chromosome segregation
    • Silkworth WT, Nardi IK, Paul R, Mogilner A, Cimini D (2012). Timing of centrosome separation is important for accurate chromosome segregation. Mol Biol Cell 23, 401-411.
    • (2012) Mol Biol Cell , vol.23 , pp. 401-411
    • Silkworth, W.T.1    Nardi, I.K.2    Paul, R.3    Mogilner, A.4    Cimini, D.5
  • 63
    • 79957900656 scopus 로고    scopus 로고
    • Differential control of Eg5-dependent centrosome separation by Plk1 and Cdk1
    • Smith E et al. (2011). Differential control of Eg5-dependent centrosome separation by Plk1 and Cdk1. EMBO J 30, 2233-2245.
    • (2011) EMBO J , vol.30 , pp. 2233-2245
    • Smith, E.1
  • 64
    • 84861204551 scopus 로고    scopus 로고
    • G protein-coupled receptor kinase 5 phosphorylates nucleophosmin and regulates cell sensitivity to polo-like kinase 1 inhibition
    • So CH, Michal AM, Mashayekhi R, Benovic JL (2012). G protein-coupled receptor kinase 5 phosphorylates nucleophosmin and regulates cell sensitivity to polo-like kinase 1 inhibition. J Biol Chem 287, 17088-17099.
    • (2012) J Biol Chem , vol.287 , pp. 17088-17099
    • So, C.H.1    Michal, A.M.2    Mashayekhi, R.3    Benovic, J.L.4
  • 66
    • 35148836216 scopus 로고    scopus 로고
    • GRK5 deficiency leads to early Alzheimer-like pathology and working memory impairment
    • DOI 10.1016/j.neurobiolaging.2006.08.013, PII S0197458006003083
    • Suo Z, Cox AA, Bartelli N, Rasul I, Festoff BW, Premont RT, Arendash GW (2007). GRK5 deficiency leads to early Alzheimer-like pathology and working memory impairment. Neurobiol Aging 28, 1873-1888. (Pubitemid 47539698)
    • (2007) Neurobiology of Aging , vol.28 , Issue.12 , pp. 1873-1888
    • Suo, Z.1    Cox, A.A.2    Bartelli, N.3    Rasul, I.4    Festoff, B.W.5    Premont, R.T.6    Arendash, G.W.7
  • 67
    • 77949900421 scopus 로고    scopus 로고
    • Kinome-wide RNAi studies in human multiple myeloma identify vulnerable kinase targets, including a lymphoid-restricted kinase, GRK6
    • Tiedemann RE et al. (2010). Kinome-wide RNAi studies in human multiple myeloma identify vulnerable kinase targets, including a lymphoid-restricted kinase, GRK6. Blood 115, 1594-1604.
    • (2010) Blood , vol.115 , pp. 1594-1604
    • Tiedemann, R.E.1
  • 68
    • 0027497584 scopus 로고
    • 1-adrenergic receptors in the failing human heart
    • Ungerer M, Bohm M, Elce JS, Erdmann E, Lohse MJ (1993). Altered expression of beta-adrenergic receptor kinase and beta 1-adrenergic receptors in the failing human heart. Circulation 87, 454-463. (Pubitemid 23040915)
    • (1993) Circulation , vol.87 , Issue.2 , pp. 454-463
    • Ungerer, M.1    Bohm, M.2    Elce, J.S.3    Erdmann, E.4    Lohse, M.J.5
  • 70
    • 0036278332 scopus 로고    scopus 로고
    • Myocyte redistribution of GRK2 and GRK5 in hypertensive, heart-failure-prone rats
    • DOI 10.1161/01.HYP.0000019130.09167.3B
    • Yi XP, Gerdes AM, Li F (2002). Myocyte redistribution of GRK2 and GRK5 in hypertensive, heart-failure-prone rats. Hypertension 39, 1058-1063. (Pubitemid 34620124)
    • (2002) Hypertension , vol.39 , Issue.6 , pp. 1058-1063
    • Yi, X.P.1    Gerdes, A.M.2    Li, F.3


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