Amelioration of Danhong injection on the lipopolysaccharide-stimulated systemic acute inflammatory reaction via multi-target strategy

Journal of Ethnopharmacology

Volumn 149, Issue 3, 2013, Pages 772-782

  Gao, Li Na ^a   Cui, Yuan Lu ^a   Wang, Qiang Song ^a   Wang, Shao Xia ^a  

^a TIANJIN UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

Anti inflammatory; Carthamus tinctorius; Polypharmacology; Salvia miltiorrhiza; Systemic inflammatory response syndrome; Traditional Chinese medicine (TCM)

Indexed keywords

ACUTE PHASE PROTEIN; ANTIINFLAMMATORY AGENT; CHEMOKINE; CHINESE DRUG; CYCLOOXYGENASE 2; CYTOKINE; DANHONG; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MESSENGER RNA; NITRIC OXIDE; PROSTAGLANDIN E2; PROTEOME; REAGENT; TUMOR NECROSIS FACTOR ALPHA ANTIBODY; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CHINESE MEDICINE; CONTROLLED STUDY; CYTOKINE RELEASE; DOWN REGULATION; ENZYME LINKED IMMUNOSORBENT ASSAY; IN VIVO STUDY; KIDNEY; LIVER; MACROPHAGE; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SERUM; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME;

CARTHAMUS TINCTORIUS; MUS; SALVIA MILTIORRHIZA;

ANTI-INFLAMMATORY; CARTHAMUS TINCTORIUS; POLYPHARMACOLOGY; SALVIA MILTIORRHIZA; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; TRADITIONAL CHINESE MEDICINE (TCM);

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELL CULTURE TECHNIQUES; CELL LINE; CELL SURVIVAL; CYCLOOXYGENASE 2; CYTOKINES; DINOPROSTONE; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUGS, CHINESE HERBAL; KIDNEY; LIPOPOLYSACCHARIDES; LIVER; MACROPHAGES; MALE; MICE; MICE, INBRED ICR; MOLECULAR TARGETED THERAPY; NITRIC OXIDE; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME;

EID: 84884413191     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2013.07.039     Document Type: Article

References (63)

1. F. Aktan iNOS-mediated nitric oxide production and its regulation Life Sciences 75 2004 639 654
2. S. Amor, F. Puentes, D. Baker, and P. Van Der Valk Inflammation in neurodegenerative diseases Immunology 129 2010 154 169
3. M. Baggiolini Chemokines and leukocyte traffic Nature 392 1998 565 568
4. C.A. Botwinski Systemic inflammatory response syndrome Neonatal Network 20 2001 21 28
5. R. Carrillo-Esper, and F.N. Nunez-Monroy Systemic inflammatory response syndrome: new concepts Gaceta Médica de México 137 2001 127 134
6. Q. Chen, D. Yi, Y. Xie, W. Yang, Y. Zhuang, and J. Du Analysis of clinical use of Danhong injection based on hospital information system Zhongguo Zhong yao za zhi= Zhongguo Zhongyao Zazhi= China Journal of Chinese Materia Medica 36 2011 2817
7. Y.H. Chen, S.J. Lin, H.H. Ku, M.S. Shiao, F.Y. Lin, J.W. Chen, and Y.L. Chen Salvianolic acid B attenuates VCAM-1 and ICAM-1 expression in TNF-α-treated human aortic endothelial cells Journal of Cellular Biochemistry 82 2001 512 521
8. M.G. Davies, and P.O. Hagen Systemic inflammatory response syndrome British Journal of Surgery 84 1997 920 935
9. R. Donadelli, M. Abbate, C. Zanchi, D. Corna, S. Tomasoni, A. Benigni, G. Remuzzi, and C. Zoja Protein traffic activates NF-kB gene signaling and promotes MCP-1-dependent interstitial inflammation American Journal of Kidney Diseases 36 2000 1226 1241
10. T. Efferth, and E. Koch Complex interactions between phytochemicals. The multi-target therapeutic concept of phytotherapy Current Drug Targets 12 2011 122 132
11. E. Fattori, M. Cappelletti, P. Costa, C. Sellitto, L. Cantoni, M. Carelli, R. Faggioni, G. Fantuzzi, P. Ghezzi, and V. Poli Defective inflammatory response in interleukin 6-deficient mice Journal of Experimental Medicine 180 1994 1243 1250
12. M. Feron, L. Guevel, K. Rouger, L. Dubreil, M.C. Arnaud, M. Ledevin, L.A. Megeney, Y. Cherel, and V. Sakanyan PTEN contributes to profound PI3K/Akt signaling pathway deregulation in dystrophin-deficient dog muscle American Journal of Pathology 174 2009 1459 1470
13. D.M. Form, and R. Auerbach PGE2 and angiogenesis In: Proceedings of the Society for Experimental Biology and Medicine 172 1983 pp. 214-218
14. S. Gando Systemic inflammatory response syndrome (SIRS) and endothelial cell injury Nihon Rinsho 62 2004 2244 2250
15. G. Guan, x.p. Hua, L. Wang, L. Du, and X. Kong Effects of Danhong injection on lipid metabolism and vascular endothelial function in rabbit model with experimental atherosclerosis [J] Journal of Clinical Cardiology 4 2007 024
16. T. Hanada, and A. Yoshimura Regulation of cytokine signaling and inflammation Cytokine & Growth Factor Reviews 13 2002 413
17. Y. He, H. Wan, Y. Du, X. Bie, T. Zhao, W. Fu, and P. Xing Protective effect of Danhong injection on cerebral ischemia-reperfusion injury in rats Journal of Ethnopharmacology 144 2012 387 394
18. D.-X. Hou, S. Masuzaki, F. Hashimoto, T. Uto, S. Tanigawa, M. Fujii, and Y. Sakata Green tea proanthocyanidins inhibit cyclooxygenase-2 expression in LPS-activated mouse macrophages: molecular mechanisms and structure-activity relationship Archives of Biochemistry and Biophysics 460 2007 67 74
19. Y.M. Huang, Z.J. Zhang, A.M. Guo, L.H. Pan, and C.E. Li Determination of protocatechuic aldehyde in Danhong injection by HPLC [J] Pharmaceutical Journal of Chinese People's Liberation Army 21 2005 467 469
20. Fang Huiqing, Pengal R.A.; X. Cao, Ganesan L.P.; Wewers M.D.; Marsh C.B.; and Tridandapani S. Lipopolysaccharide-induced macrophage inflammatory.pdf Journal of Immunology 173 2004 360 366
21. Z. Jun The treatment of severe post-traumatic SIRS by Xuebijing Chinese Journal of Medicinal Guide 2 2011 069
22. H.G. Kang, J.M. Jenabi, J. Zhang, N. Keshelava, H. Shimada, W.A. May, T. Ng, C.P. Reynolds, T.J. Triche, and P.H.B. Sorensen E-cadherin cell-cell adhesion in ewing tumor cells mediates suppression of anoikis through activation of the ErbB4 tyrosine kinase Cancer Research 67 2007 3094 3105
23. H. Kojima, and T. Nagano Fluorescent indicators for nitric oxide Advanced Materials 12 2000 763 765
24. Z. Li-jun Clinical study on elderly coronary heart disease arrhythmia patients treated by Danhong injection combined with Wenxin Granules Practical Clinical Journal of Integrated Traditional Chinese and Western Medicine 4 2011 003
25. L. Li Effects of Danhong injection on vascular endothelial function and inflammatory factors in patients with unstable Angina Pectoris Herald of Medicine 3 2011 021
26. P. Libby, P.M. Ridker, and A. Maseri Inflammation and atherosclerosis Circulation 105 2002 1135 1143
27. L. Ling, L. Lijia, and L. Tingzhu Effects of serum oxidation low density lipoprotein and c-reactive protein on coronary heart disease Guizhou Medical Journal 7 2004 004
28. G. Liu, Y. Liu, R. Liu, F. Dong, and Z. Zhang Effects of Flos carthami on CYP2D6 and on the pharmacokinetics of metoprolol in rats Evidence-Based Complementary and Alternative Medicine 2010 2011
29. H. Liu, J. Wang, W. Zhou, Y. Wang, and L. Yang Systems approaches and polypharmacology for drug discovery from herbal medicines: an example using licorice Journal of Ethnopharmacology 146 2013 773 793
30. -ΔΔCT methods Methods 25 2001 402 408
31. Y. Lu, L. Gu, and W. Huang Effect of Xuebijing injection on peripheral T-lymphocyte subpopulations in patients with severe trauma Chinese Journal of Traumatology (English Edition) 13 2010 72 76
32. Z. Lu, F. Liu, J. Hu, D. Bian, and F. Li Suppressive effects of safflower yellow on immune functions Zhongguo Yao Li Xue Bao=Acta Pharmacologica Sinica 12 1991 537
33. A.M. Marcondes, A.J. Mhyre, D.L. Stirewalt, S.H. Kim, C.A. Dinarello, and H.J. Deeg Dysregulation of IL-32 in myelodysplastic syndrome and chronic myelomonocytic leukemia modulates apoptosis and impairs NK function In: Proceedings of the National Academy of Sciences of the United States of America 105 2008 pp. 2865-2870
34. N. Matsuda, and Y. Hattori Systemic inflammatory response syndrome (SIRS): molecular pathophysiology and gene therapy Journal of Pharmacological Sciences 101 2006 186 198
35. S. Mehta The effects of nitric oxide in acute lung injury Vascular Pharmacology 43 2005 390
36. V. Mollace, C. Muscoli, E. Masini, S. Cuzzocrea, and D. Salvemini Modulation of prostaglandin biosynthesis by nitric oxide and nitric oxide donors Pharmacological Reviews 57 2005 217 252
37. S. Moncada, R. Palmer, and E. Higgs Nitric oxide: physiology, pathophysiology, and pharmacology Pharmacological Reviews 43 1991 109 142
38. S. Moncada, and A. Higgs The L-arginine-nitric oxide pathway The New England journal of medicine 329 1993 2002
39. C. Napoli, and L.J. Ignarro Nitric oxide and atherosclerosis Nitric Oxide 5 2001 88 97
40. P.O. Nystrom The systemic inflammatory response syndrome: definitions and aetiology Journal of Antimicrobial Chemotherapy 41 1998 1 7
41. G. Raspotnig, G. Fauler, A. Jantscher, W. Windischhofer, K. Schachl, and H. Leis Colorimetric determination of cell numbers by Janus green staining Analytical Biochemistry 275 1999 74 83
42. D.B. Reddy, and P. Reddanna Chebulagic acid (CA) attenuates LPS-induced inflammation by suppressing NF-κB and MAPK activation in RAW 264.7 macrophages Biochemical and Biophysical Research Communications 381 2009 112 117
43. C.M. Robertson, and C.M. Coopersmith The systemic inflammatory response syndrome Microbes and Infection 8 2006 1382 1389
44. T.D. Schmittgen, and K.J. Livak Analyzing real-time PCR data by the comparative CT method Nature Protocols 3 2008 1101 1108
45. R.M. Strieter, S.L. Kunkel, and R.C. Bone Role of tumor necrosis factor-alpha in disease states and inflammation Critical Care Medicine 21 1993 S447
46. M. Sun, J.J. Zhang, J.Z. Shan, H. Zhang, C.Y. Jin, S. Xu, and Y.L. Wang Clinical observation of Danhong injection (herbal TCM product from Radix Salviae miltiorrhizae and Flos Carthami tinctorii) in the treatment of traumatic intracranial hematoma Phytomedicine 16 2009 683 689
47. M. Tai, L. Liu, R. Ma, X. Li, J. Pang, and J. Xu General pharmacology of Danhong injection Di 1 jun yi da xue xue bao= Academic Journal of the First Medical College of PLA 25 2005 335
48. B.S. Taylor, and D.A. Geller Molecular regulation of the human inducible nitric oxide synthase (iNOS) gene Shock (Augusta, Ga.) 13 2000 413
49. K.J. Tracey The inflammatory reflex Nature 420 2002 853 859
50. H.H. Versteeg, E. Nijhuis, G.R. van den Brink, M. Evertzen, G.N. Pynaert, S. Van Deventer, P.J. Coffer, and M.P. Peppelenbosch A new phosphospecific cell-based ELISA for p42/p44 mitogen-activated protein kinase (MAPK), p38 MAPK, protein kinase B and cAMP-response-element-binding protein Biochemical Journal. 350 2000 717
51. L.H. Wan, J. Chen, L. Li, W.B. Xiong, and L.M. Zhou Protective effects of Carthamus tinctorius injection on isoprenaline-induced myocardial injury in rats Pharmaceutical Biology 49 2011 1204 1209
52. B.Z. Wang, M.R. Cao, W.H. Zou, and P.F. Dong The toxicological study of Danhong China Practical Medicine 3 2008 27 29
53. L. Wang, X. Zhang, L. Liu, L. Cui, R. Yang, M. Li, and W. Du Tanshinone II A down-regulates HMGB1, RAGE, TLR4, NF-κB expression, ameliorates BBB permeability and endothelial cell function, and protects rat brains against focal ischemia Brain Research 1321 2010 143 151
54. S.M. Wang Determination of Water-solubility component in Danhong injection by HPLC LiShiZhen Medicine and Materia Medica Research 17 2006 989 990
55. C. Weiguo, L. Zhiqin, S. Yun, and T. Yanduo A progress in pharmacological research of flavonoids Acta Botanica Boreali-Occidentalia Sinica 23 2003 2241 2247
56. M.L. Wong, B. Xie, N. Beatini, P. Phu, S. Marathe, A. Johns, P.W. Gold, E. Hirsch, K.J. Williams, J. Licinio, and I. Tabas Acute systemic inflammation up-regulates secretory sphingomyelinase in vivo: a possible link between inflammatory cytokines and atherogenesis In: Proceedings of the National Academy of Sciences of the United States of America 97 2000 pp. 8681-8686
57. L. Xie, S.L. Kinnings, and P.E. Bourne Novel computational approaches to polypharmacology as a means to define responses to individual drugs Annual Review of Pharmacology and Toxicology 52 2012 361 379
58. J.S. Yudkin, M. Kumari, S.E. Humphries, and V. Mohamed-Ali Inflammation, obesity, stress and coronary heart disease: is interleukin-6 the link? Atherosclerosis 148 2000 209 214
59. Y.J. Zhang, X. Huang, Y. Wang, Y. Xie, X.J. Qiu, P. Ren, L.C. Gao, H.H. Zhou, H.Y. Zhang, and M.Q. Qiao Ferulic acid-induced anti-depression and prokinetics similar to Chaihu-Shugan-San via polypharmacology Brain Research Bulletin 86 2011 222 228
60. G.R. Zhao, H.M. Zhang, T.X. Ye, Z.J. Xiang, Y.J. Yuan, Z.X. Guo, and L.B. Zhao Characterization of the radical scavenging and antioxidant activities of danshensu and salvianolic acid B Food and Chemical Toxicology: an International Journal Published for the British Industrial Biological Research Association 46 2008 73
61. P. Zhao, and S. Jiang Effect of danhong injection on ET-1, sP-sel, and hs-CRP in patients with acute coronary syndrome undergoing percutaneous coronary intervention Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi= Chinese journal of integrated traditional and Western medicine/Zhongguo Zhong xi yi jie he xue hui, Zhongguo Zhong yi yan jiu yuan zhu ban 31 2011 11
62. Z. Zhou, Y. Liu, A.D. Miao, and S.Q. Wang Protocatechuic aldehyde suppresses TNF-alpha-induced ICAM-1 and VCAM-1 expression in human umbilical vein endothelial cells European Journal Of Pharmacology 513 2005 1
63. D.A. Zisman, S.L. Kunkel, R.M. Strieter, W.C. Tsai, K. Bucknell, J. Wilkowski, and T.J. Standiford MCP-1 protects mice in lethal endotoxemia Journal of Clinical Investigation 99 1997 2832