Protective effect of Danhong injection on cerebral ischemia-reperfusion injury in rats

Journal of Ethnopharmacology

Volumn 144, Issue 2, 2012, Pages 387-394

  He, Yu ^a   Wan, Haitong ^a   Du, Yueguang ^a   Bie, Xiaodong ^b   Zhao, Tao ^c   Fu, Wei ^c   Xing, Panke ^c  

^a ZHEJIANG CHINESE MEDICAL UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^c Buchang Pharmaceutical Co Ltd   (China)

Author keywords

Antioxidant; Apoptosis; Danhong injection; Ischemia reperfusion; Neuroprotection

Indexed keywords

6 OXOPROSTAGLANDIN F1 ALPHA; CHINESE DRUG; DANHONG; MALONALDEHYDE; PLASMINOGEN ACTIVATOR INHIBITOR; PROTEIN BAX; PROTEIN BCL 2; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BRAIN ISCHEMIA; BRAIN PROTECTION; BRAIN SIZE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MOLECULAR MECHANICS; NEUROLOGIC DISEASE; NONHUMAN; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY; UPREGULATION;

ANIMALS; BCL-2-ASSOCIATED X PROTEIN; BRAIN; DRUGS, CHINESE HERBAL; INJECTIONS, INTRAVENOUS; MALE; MALONDIALDEHYDE; NEUROPROTECTIVE AGENTS; PHYTOTHERAPY; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY; SUPEROXIDE DISMUTASE;

MURINAE; RATTUS;

EID: 84868193837     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2012.09.025     Document Type: Article

References (54)

1. F. Abas, T. Alkan, B. Goren, O. Taskapilioglu, E. Sarandol, and S. Tolunay Neuroprotective effects of postconditioning on lipid peroxidation and apoptosis after focal cerebral ischemia/reperfusion injury in rats Turkish Neurosurgery 20 2010 1 8
2. P. Abrescia, and P. Golino Free radicals and antioxidants in cardiovascular diseases Expert Review of Cardiovascular Therapy 3 2005 159 171
3. A. Ahmad, M.M. Khan, S.S. Raza, H. Javed, M. Ashafaq, F. Islam, and M.M. Safhi Ocimum sanctum attenuates oxidative damage and neurological deficits following focal cerebral ischemia/reperfusion injury in rats Neurological sciences 2012 [Epub ahead of print]
4. P.A. Barber, R.N. Auer, A.M. Buchan, and G.R. Sutherland Understanding and managing ischemic stroke Canadian Journal of Physiology and Pharmacology 79 2001 283 296
5. F.C. Barone, E.A. Irving, A.M. Ray, J.C. Lee, S. Kassis, S. Kumar, A.M. Badger, R.F. White, M.J. McVey, J.J. Legos, J.A. Erhardt, A.H. Nelson, E.H. Ohlstein, A.J. Hunter, K. Ward, B.R. Smith, J.L. Adams, and A.A. Parsons SB 239063, a second-generation p38 mitogen-activated protein kinase inhibitor, reduces brain injury and neurological deficits in cerebral focal ischemia The Journal of Pharmacology and Experimental Therapeutics 296 2001 312 321
6. J.B. Bederson, L.H. Pitts, M. Tsuji, M.C. Nishimura, R.L. Davis, and H. Bartkowski Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination Stroke 17 1986 472 476
7. L. Belayev, O.F. Alonso, R. Busto, W. Zhao, and M.D. Ginsberg Middle cerebral artery occlusion in the rat by intraluminal suture. Neurological and pathological evaluation of an improved model Stroke 27 1996 1616 1622 discussion 1623
8. L. Belayev, R. Busto, W. Zhao, and M.D. Ginsberg HU-211, a novel noncompetitive N-methyl-D-aspartate antagonist, improves neurological deficit and reduces infarct volume after reversible focal cerebral ischemia in the rat Stroke 26 1995 2313 2319 discussion 2319-2320
9. Q. Chen, D. Yi, Y. Xie, W. Yang, Y. Zhuang, and J. Du Analysis of clinical use of Danhong injection based on hospital information system Zhongguo Zhong Yao Za Zhi 36 2011 2817 2820
10. Y.F. Chen Traditional Chinese herbal medicine and cerebral ischemia Frontiers in Bioscience (Elite edition) 4 2012 809 817
11. C. Cheyuo, A. Jacob, R. Wu, M. Zhou, L. Qi, W. Dong, Y. Ji, W.W. Chaung, H. Wang, J. Nicastro, G.F. Coppa, and P. Wang Recombinant human MFG-E8 attenuates cerebral ischemic injury: its role in anti-inflammation and anti-apoptosis Neuropharmacology 62 2012 890 900
12. C.T. Chien, T.C. Chang, C.Y. Tsai, S.K. Shyue, and M.K. Lai Adenovirus-mediated bcl-2 gene transfer inhibits renal ischemia/reperfusion induced tubular oxidative stress and apoptosis American Journal of Transplantation 5 2005 1194 1203
13. M. Cini, R.G. Fariello, A. Bianchetti, and A. Moretti Studies on lipid peroxidation in the rat brain Neurochemical Research 19 1994 283 288
14. J.W. Dong, H.F. Zhu, W.Z. Zhu, H.L. Ding, T.M. Ma, and Z.N. Zhou Intermittent hypoxia attenuates ischemia/reperfusion induced apoptosis in cardiac myocytes via regulating Bcl-2/Bax expression Cell Research 13 2003 385 391
15. K.P. Doyle, R.P. Simon, and M.P. Stenzel-Poore Mechanisms of ischemic brain damage Neuropharmacology 55 2008 310 318
16. R.J. Gryglewski Prostacyclin among prostanoids Pharmacological Reports 60 2008 3 11
17. R. Guo, G.F. Zhao, Z. Feng, and L.L. Hao Effect of Danhong injection on serum matrix metalloproteinase-9 (MMP-9) and its clinical efficacy in patients with cerebral infarction Chinese Journal of Practical Nervous Diseases 13 2010 3
18. X.L. Hu, T. Olsson, I.M. Johansson, T. Brannstrom, and P. Wester Dynamic changes of the anti- and pro-apoptotic proteins Bcl-w, Bcl-2, and Bax with Smac/Diablo mitochondrial release after photothrombotic ring stroke in rats European journal of neuroscience 20 2004 1177 1188
19. Q. Hua, X.L. Zhu, P.T. Li, Y. Liu, N. Zhang, Y. Xu, and X. Jia The inhibitory effects of cholalic acid and hyodeoxycholalic acid on the expression of TNFalpha and IL-1beta after cerebral ischemia in rats Archives of Pharmacal Research 32 2009 65 73
20. M. Imanishi, T. Tsuji, S. Nakamura, and M. Takamiya Prostaglandin I(2)/E(2) ratios in unilateral renovascular hypertension of different severities Hypertension 38 2001 23 29
21. H. Jaffer, V.B. Morris, D. Stewart, and V. Labhasetwar Advances in Stroke Therapy Drug Delivery and Translational Research 1 2011 409 419
22. H.S. Kim, M.S. Park, J.K. Lee, H.J. Kim, J.T. Park, and M.C. Lee Time point expression of apoptosis regulatory proteins in a photochemically-induced focal cerebral ischemic rat brain Chonnam Medical Journal 47 2011 144 149
23. A. Kunz, U. Dirnagl, and P. Mergenthaler Acute pathophysiological processes after ischaemic and traumatic brain injury Best Practice & Research Clinical Anaesthesiology 24 2010 495 509
24. H.M. Li Clinical observation on Danhong injection in treating acute cerebral infarction China Journal of Chinese Medicine 26 2011 1234 1235
25. J. Liu, and B. Zhang Centralized monitoring and analysis on 400 cases of Danhong injection treatments International Journal of Traditional Chinese Medicine 33 2011 701 703
26. J. Liu, D. Zhang, J. Li, J. Feng, X. Yang, D. Shi, and X. Liang Effects of Salvia miltiorrhiza and Carthamus tinctorius aqueous extracts and compatibility on rat myocardial ischemic reperfusion injury Zhongguo Zhong Yao Za Zhi 36 2011 189 194
27. N.R. Madamanchi, A. Vendrov, and M.S. Runge Oxidative stress and vascular disease Arteriosclerosis Thrombosis and Vascular Biology 25 2005 29 38
28. H. Mai, Y. S.; M. Y.; T. H.; and T. U. Neuroprotective effect of a prostacyclin agonist (ONO-1301) with thromboxane synthase inhibitory activity in rats subjected to cerebral ischemia Pharmacology & Pharmacy 2011 306 314
29. J.C. Martinou, and R.J. Youle Mitochondria in apoptosis: Bcl-2 family members and mitochondrial dynamics Developmental cell 21 2011 92 101
30. N. Matijevic, and K.K. Wu Hypercoagulable states and strokes Current Atherosclerosis Reports 8 2006 324 329
31. J. Murdoch, and R. Hall Brain protection: physiological and pharmacological considerations. Part I: the physiology of brain injury Canadian Journal of Anaesthesia 37 1990 663 671
32. V.P. Nakka, A. Gusain, S.L. Mehta, and R. Raghubir Molecular mechanisms of apoptosis in cerebral ischemia: multiple neuroprotective opportunities Molecular Neurobiology 37 2008 7 38
33. S. Nasiraei-Moghadam, B. Kazeminezhad, L. Dargahi, and A. Ahmadiani Maternal oral consumption of morphine increases Bax/Bcl-2 ratio and caspase 3 activity during early neural system development in rat embryos Journal of Molecular Neuroscience 41 2010 156 164
34. S.K. Powers, and M.J. Jackson Exercise-induced oxidative stress: cellular mechanisms and impact on muscle force production Physiological Reviews 88 2008 1243 1276
35. P. Reinstrup, and C.H. Nordstrom Prostacyclin infusion may prevent secondary damage in pericontusional brain tissue Neurocritical Care 14 2011 441 446
36. T. Rosse, R. Olivier, L. Monney, M. Rager, S. Conus, I. Fellay, B. Jansen, and C. Borner Bcl-2 prolongs cell survival after Bax-induced release of cytochrome c Nature 391 1998 496 499
37. S. Salakou, D. Kardamakis, A.C. Tsamandas, V. Zolota, E. Apostolakis, V. Tzelepi, P. Papathanasopoulos, D.S. Bonikos, T. Papapetropoulos, T. Petsas, and D. Dougenis Increased Bax/Bcl-2 ratio up-regulates caspase-3 and increases apoptosis in the thymus of patients with myasthenia gravis In Vivo 21 2007 123 132
38. G. Schreibelt, J. van Horssen, S. van Rossum, C.D. Dijkstra, B. Drukarch, and H.E. de Vries Therapeutic potential and biological role of endogenous antioxidant enzymes in multiple sclerosis pathology Brain Research Reviews 56 2007 322 330
39. SFDA, 2002. National Drugs surveillance administrative bureau standard WS-11220 (ZD-1220)-2002.
40. J. Stitham, C. Midgett, K.A. Martin, and J. Hwa Prostacyclin: an inflammatory paradox Frontiers in Pharmacology 2 2011 24
41. M. Sun, J.J. Zhang, J.Z. Shan, H. Zhang, C.Y. Jin, S. Xu, and Y.L. Wang Clinical observation of Danhong Injection (herbal TCM product from Radix Salviae miltiorrhizae and Flos Carthami tinctorii) in the treatment of traumatic intracranial hematoma Phytomedicine 16 2009 683 689
42. M.H. Tai, L.M. Liu, R.Q. Ma, X. Li, J.X. Pang, and J.P. Xu General pharmacology of Danhong injection Di Yi Jun Yi Da Xue Xue Bao 25 2005 335 338
43. S.G. Thompson, J. Kienast, S.D. Pyke, F. Haverkate, and J.C. van de Loo Hemostatic factors and the risk of myocardial infarction or sudden death in patients with angina pectoris. European Concerted Action on Thrombosis and Disabilities Angina Pectoris Study Group The New England Journal of Medicine 332 1995 635 641
44. Y. Tsujimoto, and S. Shimizu Bcl-2 family: life-or-death switch FEBS Letters 466 2000 6 10
45. B.A. Vuckovic, M.J. Djeric, T.A. Ilic, V.B. Canak, S. Kojic-Damjanov, M.G. Zarkov, and V.S. Cabarkapa Fibrinolytic parameters, lipid status and lipoprotein(a) in ischemic stroke patients Srpski arhiv za Celokupno Lekarstvo 138 1 2010 12 17
46. J.W. Wang, W.G. Shi, and J.T. Bi Effects of Danhong Injection on the inflammatory reactants and fibrinolytic activity in unstable angina Chinese Journal of Integrative Medicine on Cardio/Cerebrovascular Disease 5 2007 673 675
47. Z. Wang, T. Liu, L. Gan, T. Wang, X. Yuan, B. Zhang, H. Chen, and Q. Zheng Shikonin protects mouse brain against cerebral ischemia/reperfusion injury through its antioxidant activity European Journal of Pharmacology 643 2010 211 217
48. C.J. Wu, J.T. Chen, T.L. Yen, T. Jayakumar, D.S. Chou, G. Hsiao, and J.R. Sheu Neuroprotection by the Traditional Chinese Medicine, Tao-Hong-Si-Wu-Tang, against Middle Cerebral Artery Occlusion-Induced Cerebral Ischemia in Rats Evidence-based Complementary and Alternative Medicine 2011 2011 803015
49. R.J. Wurtman, and N.T. Zervas Monoamine neurotransmitters and the pathophysiology of stroke and central nervous system trauma Journal of Neurosurgery 40 1974 34 36
50. Y. Zhan, J.P. Xu, J.B. Liang, L.S. Sheng, B.R. Xiang, Q.G. Zou, and Z.J. Zhang Simultaneous LC-MS-MS analysis of danshensu, salvianolic acid B, and hydroxysafflor yellow A in beagle dog plasma, and application of the method to a pharmacokinetic study of danhong lyophilized powder for injection Chromatographia 68 2008 71 79
51. T. Zhao, J. Han, Y. Chen, H. Wan, and X. Bie The mechanism of 3-methoxy puerarin on decreasing the cerebral ischemia-reperfusion injury in rats Asia Pacific Journal of Clinical Nutrition 16 1 2007 302 304
52. Z.Y. Zhou, Y.P. Tang, J. Xiang, P. Wua, H.M. Jin, Z. Wang, M. Mori, and D.F. Cai Neuroprotective effects of water-soluble Ganoderma lucidum polysaccharides on cerebral ischemic injury in rats Journal of Ethnopharmacology 131 2010 154 164
53. H.B. Zhu, L. Zhang, Z.H. Wang, J.W. Tian, F.H. Fu, K. Liu, and C.L. Li Therapeutic effects of hydroxysafflor yellow A on focal cerebral ischemic injury in rats and its primary mechanisms Journal of Asian Natural Products Research 7 2005 607 613
54. T.Y. Zhu, and Y.D. Cui Clinical observations of Danhong injection treatment on ischemic stroke Chinese Journal of Practical Nervous Diseases 2010 80 82