Chebulagic acid (CA) attenuates LPS-induced inflammation by suppressing NF-κB and MAPK activation in RAW 264.7 macrophages

Biochemical and Biophysical Research Communications

Volumn 381, Issue 1, 2009, Pages 112-117

  Reddy, D Bharat ^a   Reddanna, Pallu ^a  

^a UNIVERSITY OF HYDERABAD   (India)

Author keywords

Chebulagic acid (CA); Lipopolysaccharide (LPS); Nitric oxide (NO); Nuclear factor B (NF B); Prostaglandin E2 (PGE2); Reactive oxygen species (ROS)

Indexed keywords

ARACHIDONATE 5 LIPOXYGENASE; CHEBULAGIC ACID; CYCLOOXYGENASE 2; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; NITRIC OXIDE; PROSTAGLANDIN E2; PROTEIN P50; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; SYNAPTOTAGMIN I; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL LINE; CELL STIMULATION; CONCENTRATION RESPONSE; DOWN REGULATION; ENZYME ACTIVATION; INFLAMMATION; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTIOXIDANTS; BENZOPYRANS; CELL LINE; CYCLOOXYGENASE 2; GLUCOSIDES; INFLAMMATION; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; NADP; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE II; PHOSPHORYLATION; REACTIVE OXYGEN SPECIES;

EID: 61649101186     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2009.02.022     Document Type: Article

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