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Volumn 81, Issue 10, 2013, Pages 3942-3957

New role for DCR-1/Dicer in caenorhabditis elegans innate immunity against the highly virulent bacterium bacillus thuringiensis DB27

Author keywords

[No Author keywords available]

Indexed keywords

DICER; MICRORNA; MITOGEN ACTIVATED PROTEIN KINASE P38;

EID: 84884401665     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00700-13     Document Type: Article
Times cited : (23)

References (78)
  • 1
    • 72949096858 scopus 로고    scopus 로고
    • Evolution of host innate defence: insights from Caenorhabditis elegans and primitive invertebrates
    • Irazoqui JE, Urbach JM, Ausubel FM. 2010. Evolution of host innate defence: insights from Caenorhabditis elegans and primitive invertebrates. Nat. Rev. Immunol. 10:47-58.
    • (2010) Nat. Rev. Immunol. , vol.10 , pp. 47-58
    • Irazoqui, J.E.1    Urbach, J.M.2    Ausubel, F.M.3
  • 2
    • 84857064084 scopus 로고    scopus 로고
    • Immune defense mechanisms in the Caenorhabditis elegans intestinal epithelium
    • Pukkila-Worley R, Ausubel FM. 2012. Immune defense mechanisms in the Caenorhabditis elegans intestinal epithelium. Curr. Opin. Immunol. 24:3-9.
    • (2012) Curr. Opin. Immunol. , vol.24 , pp. 3-9
    • Pukkila-Worley, R.1    Ausubel, F.M.2
  • 3
    • 79952634846 scopus 로고    scopus 로고
    • Genetic and molecular analysis of nematode- microbe interactions
    • Tan M-W, Shapira M. 2011. Genetic and molecular analysis of nematode- microbe interactions. Cell. Microbiol. 13:497-507.
    • (2011) Cell. Microbiol. , vol.13 , pp. 497-507
    • Tan, M.-W.1    Shapira, M.2
  • 4
    • 77951606304 scopus 로고    scopus 로고
    • Signal transduction pathways that function in both development and innate immunity
    • Partridge FA, Gravato-Nobre MJ, Hodgkin J. 2010. Signal transduction pathways that function in both development and innate immunity. Dev. Dyn. 239:1330-1336.
    • (2010) Dev. Dyn. , vol.239 , pp. 1330-1336
    • Partridge, F.A.1    Gravato-Nobre, M.J.2    Hodgkin, J.3
  • 5
    • 1642463846 scopus 로고    scopus 로고
    • Evolution of the innate immune system: the worm perspective
    • Schulenburg H, Kurz CL, Ewbank JJ. 2004. Evolution of the innate immune system: the worm perspective. Immunol. Rev. 198:36-58.
    • (2004) Immunol. Rev. , vol.198 , pp. 36-58
    • Schulenburg, H.1    Kurz, C.L.2    Ewbank, J.J.3
  • 7
    • 11844262607 scopus 로고    scopus 로고
    • Evolutionary perspectives on innate immunity from the study of Caenorhabditis elegans
    • Kim DH, Ausubel FM. 2005. Evolutionary perspectives on innate immunity from the study of Caenorhabditis elegans. Curr. Opin. Immunol. 17:4-10.
    • (2005) Curr. Opin. Immunol. , vol.17 , pp. 4-10
    • Kim, D.H.1    Ausubel, F.M.2
  • 8
    • 41549093748 scopus 로고    scopus 로고
    • Genome-wide investigation reveals pathogen-specific and shared signatures in the response of Caenorhabditis elegans to infection
    • doi:10.1186/gb-2007-8-9-r194.
    • Wong D, Bazopoulou D, Pujol N, Tavernarakis N, Ewbank J. 2007. Genome-wide investigation reveals pathogen-specific and shared signatures in the response of Caenorhabditis elegans to infection. Genome Biol. 8:R194. doi:10.1186/gb-2007-8-9-r194.
    • (2007) Genome Biol , vol.8 , pp. 194
    • Wong, D.1    Bazopoulou, D.2    Pujol, N.3    Tavernarakis, N.4    Ewbank, J.5
  • 9
    • 33746727711 scopus 로고    scopus 로고
    • Genomic clusters, putative pathogen recognition molecules, and antimicrobial genes are induced by infection of C
    • O'Rourke D, Baban D, Demidova M, Mott R, Hodgkin J. 2006. Genomic clusters, putative pathogen recognition molecules, and antimicrobial genes are induced by infection of C. elegans with M. nematophilum. Genome Res. 16:1005-1016.
    • (2006) elegans with M. nematophilum. Genome Res. , vol.16 , pp. 1005-1016
    • O'Rourke, D.1    Baban, D.2    Demidova, M.3    Mott, R.4    Hodgkin, J.5
  • 11
    • 84867006700 scopus 로고    scopus 로고
    • System wide analysis of the evolution of innate immunity in the nematode model species Caenorhabditis elegans and Pristionchus pacificus
    • doi:10.1371/journal.pone.0044255.
    • Sinha A, Rae R, Iatsenko I, Sommer RJ. 2012. System wide analysis of the evolution of innate immunity in the nematode model species Caenorhabditis elegans and Pristionchus pacificus. PLoS One 7:e44255. doi:10.1371/journal.pone.0044255.
    • (2012) PLoS One , vol.7 , pp. 44255
    • Sinha, A.1    Rae, R.2    Iatsenko, I.3    Sommer, R.J.4
  • 12
    • 84861129960 scopus 로고    scopus 로고
    • Caenorhabditis elegans, a model organism for investigating immunity
    • Marsh EK, May RC. 2012. Caenorhabditis elegans, a model organism for investigating immunity. Appl. Environ. Microbiol. 78:2075-2081.
    • (2012) Appl. Environ. Microbiol. , vol.78 , pp. 2075-2081
    • Marsh, E.K.1    May, R.C.2
  • 15
    • 79952233647 scopus 로고    scopus 로고
    • New models of microsporidiosis: infections in zebrafish, C
    • doi:101371/journal.ppat.1001243.
    • Troemel ER. 2011. New models of microsporidiosis: infections in zebrafish, C. elegans, and honey bee. PLoS Pathog. 7:e1001243. doi:10.1371/journal.ppat.1001243.
    • (2011) elegans, and honey bee. PLoS Pathog , vol.7 , pp. 1001243
    • Troemel, E.R.1
  • 16
    • 84864578686 scopus 로고    scopus 로고
    • Genome-wide identification of Pseudomonas aeruginosa virulence-related genes using a Caenorhabditis elegans infection model
    • doi:101371/journal.ppat.1002813.
    • Feinbaum RL, Urbach JM, Liberati NT, Djonovic S, Adonizio A, Carvunis A-R, Ausubel FM. 2012. Genome-wide identification of Pseudomonas aeruginosa virulence-related genes using a Caenorhabditis elegans infection model. PLoS Pathog. 8:e1002813. doi:10.1371/journal.ppat.1002813.
    • (2012) PLoS Pathog , vol.8 , pp. 1002813
    • Feinbaum, R.L.1    Urbach, J.M.2    Liberati, N.T.3    Djonovic, S.4    Adonizio, A.5    Carvunis, A.-R.6    Ausubel, F.M.7
  • 18
    • 77952173270 scopus 로고    scopus 로고
    • Multiple reciprocal adaptations and rapid genetic change upon experimental coevolution of an animal host and its microbial parasite
    • Schulte RD, Makus C, Hasert B, Michiels NK, Schulenburg H. 2010. Multiple reciprocal adaptations and rapid genetic change upon experimental coevolution of an animal host and its microbial parasite. Proc. Natl. Acad. Sci. U. S. A. 107:7359-7364.
    • (2010) Proc. Natl. Acad. Sci. U. S. A. , vol.107 , pp. 7359-7364
    • Schulte, R.D.1    Makus, C.2    Hasert, B.3    Michiels, N.K.4    Schulenburg, H.5
  • 19
    • 33847624102 scopus 로고    scopus 로고
    • Mode of action of Bacillus thuringiensis Cry and Cyt toxins and their potential for insect control
    • Bravo A, Gill SS, Soberón M. 2007. Mode of action of Bacillus thuringiensis Cry and Cyt toxins and their potential for insect control. Toxicon 49:423-435.
    • (2007) Toxicon , vol.49 , pp. 423-435
    • Bravo, A.1    Gill, S.S.2    Soberón, M.3
  • 21
    • 2442636542 scopus 로고    scopus 로고
    • Pore worms: using Caenorhabditis elegans to study how bacterial toxins interact with their target host
    • Huffman DL, Bischof LJ, Griffitts JS, Aroian RV. 2004. Pore worms: using Caenorhabditis elegans to study how bacterial toxins interact with their target host. Int. J. Med. Microbiol. 293:599-607.
    • (2004) Int. J. Med. Microbiol. , vol.293 , pp. 599-607
    • Huffman, D.L.1    Bischof, L.J.2    Griffitts, J.S.3    Aroian, R.V.4
  • 22
    • 0035800468 scopus 로고    scopus 로고
    • Bt toxin resistance from loss of a putative carbohydrate-modifying enzyme
    • Griffitts JS, Whitacre JL, Stevens DE, Aroian RV. 2001. Bt toxin resistance from loss of a putative carbohydrate-modifying enzyme. Science 293:860-864.
    • (2001) Science , vol.293 , pp. 860-864
    • Griffitts, J.S.1    Whitacre, J.L.2    Stevens, D.E.3    Aroian, R.V.4
  • 24
    • 74549201550 scopus 로고    scopus 로고
    • Hypoxia and the hypoxic response pathway protect against pore-forming toxins in C
    • doi:101371/journal.ppat.1000689
    • Bellier A, Chen C-S, Kao C-Y, Cinar HN, Aroian RV. 2009. Hypoxia and the hypoxic response pathway protect against pore-forming toxins in C. elegans. PLoS Pathog. 5:e1000689. doi:10.1371/journal.ppat.1000689.
    • (2009) elegans. PLoS Pathog , vol.5 , pp. 1000689
    • Bellier, A.1    Chen, C.-S.2    Kao, C.-Y.3    Cinar, H.N.4    Aroian, R.V.5
  • 25
    • 55449127739 scopus 로고    scopus 로고
    • Activation of the unfolded protein response is required for defenses against bacterial pore-forming toxin in vivo
    • doi:101371/journal.ppat.1000176
    • Bischof LJ, Kao C-Y, Los FCO, Gonzalez MR, Shen Z, Briggs SP, Van der Goot FG, Aroian RV. 2008. Activation of the unfolded protein response is required for defenses against bacterial pore-forming toxin in vivo. PLoS Pathog. 4:e1000176. doi:10.1371/journal.ppat.1000176.
    • (2008) PLoS Pathog , vol.4 , pp. 1000176
    • Bischof, L.J.1    Kao, C.-Y.2    Los, F.C.O.3    Gonzalez, M.R.4    Shen, Z.5    Briggs, S.P.6    Van der Goot, F.G.7    Aroian, R.V.8
  • 27
    • 79951622570 scopus 로고    scopus 로고
    • RAB-5-and RAB-11-dependent vesicle-trafficking pathways are required for plasma membrane repair after attack by bacterial pore-forming toxin
    • Los FCO, Kao C-Y, Smitham J, McDonald KL, Ha C, Peixoto CA, Aroian RV. 2011. RAB-5-and RAB-11-dependent vesicle-trafficking pathways are required for plasma membrane repair after attack by bacterial pore-forming toxin. Cell Host Microbe 9:147-157.
    • (2011) Cell Host Microb , vol.9 , pp. 147-157
    • Los, F.C.O.1    Kao, C.-Y.2    Smitham, J.3    McDonald, K.L.4    Ha, C.5    Peixoto, C.A.6    Aroian, R.V.7
  • 28
    • 84864798405 scopus 로고    scopus 로고
    • Population dynamics and habitat sharing of natural populations of Caenorhabditis elegans and C
    • doi:101186/1741-7007-10-59
    • Félix M-A, Duveau F. 2012. Population dynamics and habitat sharing of natural populations of Caenorhabditis elegans and C. briggsae. BMC Biol. 10:59. doi:10.1186/1741-7007-10-59.
    • (2012) briggsae. BMC Biol. , vol.10 , pp. 59
    • Félix, M.-A.1    Duveau, F.2
  • 29
    • 77952911606 scopus 로고    scopus 로고
    • Haplotype diversity of the nematode Pristionchus pacificus on Réunion in the Indian Ocean suggests multiple independent invasions
    • Herrmann M, Kienle S, Rochat J, Mayer WE, Sommer RJ. 2010. Haplotype diversity of the nematode Pristionchus pacificus on Réunion in the Indian Ocean suggests multiple independent invasions. Biol. J. Linn. Soc. 100:170-179.
    • (2010) Biol. J. Linn. Soc. , vol.100 , pp. 170-179
    • Herrmann, M.1    Kienle, S.2    Rochat, J.3    Mayer, W.E.4    Sommer, R.J.5
  • 31
    • 78249256637 scopus 로고    scopus 로고
    • A subset of naturally isolated Bacillus strains show extreme virulence to the free-living nematodes Caenorhabditis elegans and Pristionchus pacificus
    • Rae R, Iatsenko I, Witte H, Sommer RJ. 2010. A subset of naturally isolated Bacillus strains show extreme virulence to the free-living nematodes Caenorhabditis elegans and Pristionchus pacificus. Environ. Microbiol. 12:3007-3021.
    • (2010) Environ. Microbiol. , vol.12 , pp. 3007-3021
    • Rae, R.1    Iatsenko, I.2    Witte, H.3    Sommer, R.J.4
  • 32
    • 84863826292 scopus 로고    scopus 로고
    • The importance of being regular: Caenorhabditis elegans and Pristionchus pacificus defecation mutants are hypersusceptibile to bacterial pathogens
    • Rae R, Witte H, Rödelsperger C, Sommer RJ. 2012. The importance of being regular: Caenorhabditis elegans and Pristionchus pacificus defecation mutants are hypersusceptibile to bacterial pathogens. Int. J. Parasitol. 42:747-753.
    • (2012) Int. J. Parasitol. , vol.42 , pp. 747-753
    • Rae, R.1    Witte, H.2    Rödelsperger, C.3    Sommer, R.J.4
  • 34
    • 38449103045 scopus 로고    scopus 로고
    • Genetic mapping and manipulation: chapter 7-making compound mutants
    • 14 June, posting date
    • Fay D. 14 June 2006, posting date. Genetic mapping and manipulation: chapter 7-making compound mutants. In The C. elegans Research Community (ed), WormBook, http://www.wormbook.org.doi/10.1895/wormbook.1.96.2.
    • (2006) In The C. elegans Research Community (ed), WormBook
    • Fay, D.1
  • 36
    • 0025942107 scopus 로고
    • Efficient gene transfer in C. elegans: extrachromosomal maintenance and integration of transforming sequences.
    • Mello CC, Kramer JM, Stinchcomb D, Ambros V. 1991. Efficient gene transfer in C. elegans: extrachromosomal maintenance and integration of transforming sequences. EMBO J. 10:3959-3970.
    • (1991) EMBO J , vol.10 , pp. 3959-3970
    • Mello, C.C.1    Kramer, J.M.2    Stinchcomb, D.3    Ambros, V.4
  • 37
    • 0036214657 scopus 로고    scopus 로고
    • PCR fusion-based approach to create reporter gene constructs for expression analysis in transgenic C. elegans.
    • Hobert O. 2002. PCR fusion-based approach to create reporter gene constructs for expression analysis in transgenic C. elegans. Biotechniques 32: 728-730.
    • (2002) Biotechniques , vol.32 , pp. 728-730
    • Hobert, O.1
  • 38
    • 67649884743 scopus 로고    scopus 로고
    • Fast and accurate short read alignment with Burrows- Wheeler transform
    • Li H, Durbin R. 2009. Fast and accurate short read alignment with Burrows- Wheeler transform. Bioinformatics 25:1754-1760.
    • (2009) Bioinformatics , vol.25 , pp. 1754-1760
    • Li, H.1    Durbin, R.2
  • 40
    • 33646501892 scopus 로고    scopus 로고
    • Diverse chromatin remodeling genes antagonize the Rb-involved SynMuv pathways in C
    • doi:101371/journal.pgen.0020074
    • Cui M, Kim EB, Han M. 2006. Diverse chromatin remodeling genes antagonize the Rb-involved SynMuv pathways in C. elegans. PLoS Genet. 2:e74. doi:10.1371/journal.pgen.0020074.
    • (2006) elegans. PLoS Genet , vol.2 , pp. 74
    • Cui, M.1    Kim, E.B.2    Han, M.3
  • 41
    • 84862303959 scopus 로고    scopus 로고
    • Divergent gene expression in the conserved dauer stage of the nematodes Pristionchus pacificus and Caenorhabditis elegans
    • doi:101186/1471-2164-13-254
    • Sinha A, Sommer RJ, Dieterich C. 2012. Divergent gene expression in the conserved dauer stage of the nematodes Pristionchus pacificus and Caenorhabditis elegans. BMC Genomics 13:254. doi:10.1186/1471-2164-13-254.
    • (2012) BMC Genomics , vol.13 , pp. 254
    • Sinha, A.1    Sommer, R.J.2    Dieterich, C.3
  • 43
    • 62449145675 scopus 로고    scopus 로고
    • The G protein-coupled receptor FSHR-1 is required for the Caenorhabditis elegans innate immune response
    • Powell JR, Kim DH, Ausubel FM. 2009. The G protein-coupled receptor FSHR-1 is required for the Caenorhabditis elegans innate immune response. Proc. Natl. Acad. Sci. U. S. A. 106:2782-2787.
    • (2009) Proc. Natl. Acad. Sci. U. S. A. , vol.106 , pp. 2782-2787
    • Powell, J.R.1    Kim, D.H.2    Ausubel, F.M.3
  • 45
    • 77649135472 scopus 로고    scopus 로고
    • An essential role for XBP-1 in host protection against immune activation in C. elegans.
    • Richardson CE, Kooistra T, Kim DH. 2010. An essential role for XBP-1 in host protection against immune activation in C. elegans. Nature 463: 1092-1095.
    • (2010) Nature , vol.463 , pp. 1092-1095
    • Richardson, C.E.1    Kooistra, T.2    Kim, D.H.3
  • 46
    • 70349668990 scopus 로고    scopus 로고
    • Nucleolar proteins suppress Caenorhabditis elegans innate immunity by inhibiting p53/CEP-1
    • doi:101371/journal.pgen.1000657
    • Fuhrman LE, Goel AK, Smith J, Shianna KV, Aballay A. 2009. Nucleolar proteins suppress Caenorhabditis elegans innate immunity by inhibiting p53/CEP-1. PLoS Genet. 5:e1000657. doi:10.1371/journal.pgen.1000657.
    • (2009) PLoS Genet , vol.5 , pp. 1000657
    • Fuhrman, L.E.1    Goel, A.K.2    Smith, J.3    Shianna, K.V.4    Aballay, A.5
  • 47
    • 40849098017 scopus 로고    scopus 로고
    • DAF-16-dependent suppression of immunity during reproduction in Caenorhabditis elegans
    • Miyata S, Begun J, Troemel ER, Ausubel FM. 2008. DAF-16-dependent suppression of immunity during reproduction in Caenorhabditis elegans. Genetics 178:903-918.
    • (2008) Genetics , vol.178 , pp. 903-918
    • Miyata, S.1    Begun, J.2    Troemel, E.R.3    Ausubel, F.M.4
  • 48
    • 84861459438 scopus 로고    scopus 로고
    • Systematic analysis of tissuerestricted miRISCs reveals a broad role for microRNAs in suppressing basal activity of the C
    • Kudlow BA, Zhang L, Han M. 2012. Systematic analysis of tissuerestricted miRISCs reveals a broad role for microRNAs in suppressing basal activity of the C. elegans pathogen response. Mol. Cell 46:530-541.
    • (2012) elegans pathogen response. Mol. Cell , vol.46 , pp. 530-541
    • Kudlow, B.A.1    Zhang, L.2    Han, M.3
  • 49
    • 0017859452 scopus 로고
    • Characterization of temperature-sensitive, fertilization- defective mutants of the nematode caenorhabditis elegans
    • Ward S, Miwa J. 1978. Characterization of temperature-sensitive, fertilization- defective mutants of the nematode caenorhabditis elegans. Genetics 88:285-303.
    • (1978) Genetics , vol.88 , pp. 285-303
    • Ward, S.1    Miwa, J.2
  • 50
    • 53249091939 scopus 로고    scopus 로고
    • Caenorhabditis elegans mutant allele identification by whole-genome sequencing
    • Sarin S, Prabhu S, O'Meara MM, Pe'er I, Hobert O. 2008. Caenorhabditis elegans mutant allele identification by whole-genome sequencing. Nat. Methods 5:865-867.
    • (2008) Nat. Methods , vol.5 , pp. 865-867
    • Sarin, S.1    Prabhu, S.2    O'Meara, M.M.3    Pe'er, I.4    Hobert, O.5
  • 51
    • 33748929687 scopus 로고    scopus 로고
    • The PLZF-like protein TRA-4 cooperates with the Gli-like transcription factor TRA-1 to promote female development in C. elegans.
    • Grote P, Conradt B. 2006. The PLZF-like protein TRA-4 cooperates with the Gli-like transcription factor TRA-1 to promote female development in C. elegans. Dev. Cell 11:561-573.
    • (2006) Dev. Cell , vol.11 , pp. 561-573
    • Grote, P.1    Conradt, B.2
  • 59
    • 77955596719 scopus 로고    scopus 로고
    • C. elegans germline-deficient mutants respond to pathogen infection using shared and distinct mechanisms.
    • doi:101371/journal.pone.0011777
    • TeKippe M, Aballay A. 2010. C. elegans germline-deficient mutants respond to pathogen infection using shared and distinct mechanisms. PLoS One 5:e11777. doi:10.1371/journal.pone.0011777.
    • (2010) PLoS One , vol.5 , pp. 11777
    • TeKippe, M.1    Aballay, A.2
  • 60
    • 0037127026 scopus 로고    scopus 로고
    • Regulation of life-span by germ-line stem cells in Caenorhabditis elegans
    • Arantes-Oliveira N, Apfeld J, Dillin A, Kenyon C. 2002. Regulation of life-span by germ-line stem cells in Caenorhabditis elegans. Science 295: 502-505.
    • (2002) Science , vol.295 , pp. 502-505
    • Arantes-Oliveira, N.1    Apfeld, J.2    Dillin, A.3    Kenyon, C.4
  • 61
    • 71549147194 scopus 로고    scopus 로고
    • Requirement for the ERI/DICER complex in endogenous RNA interference and sperm development in Caenorhabditis elegans
    • Pavelec DM, Lachowiec J, Duchaine TF, Smith HE, Kennedy S. 2009. Requirement for the ERI/DICER complex in endogenous RNA interference and sperm development in Caenorhabditis elegans. Genetics 183: 1283-1295.
    • (2009) Genetics , vol.183 , pp. 1283-1295
    • Pavelec, D.M.1    Lachowiec, J.2    Duchaine, T.F.3    Smith, H.E.4    Kennedy, S.5
  • 62
    • 84869029982 scopus 로고    scopus 로고
    • The slicing activity of miRNA-specific Argonautes is essential for the miRNA pathway in C. elegans.
    • Bouasker S, Simard MJ. 2012. The slicing activity of miRNA-specific Argonautes is essential for the miRNA pathway in C. elegans. Nucleic Acids Res. 40:10452-10462.
    • (2012) Nucleic Acids Res. , vol.40 , pp. 10452-10462
    • Bouasker, S.1    Simard, M.J.2
  • 66
    • 66749110375 scopus 로고    scopus 로고
    • Analysis of gene expression profiles in HeLa cells in response to overexpression or siRNA-mediated depletion of NASP
    • doi: 10.1186/1477-7827-7-45
    • Alekseev OM, Richardson RT, Alekseev O, O'Rand MG. 2009. Analysis of gene expression profiles in HeLa cells in response to overexpression or siRNA-mediated depletion of NASP. Reprod. Biol. Endocrinol. 7:45. doi: 10.1186/1477-7827-7-45.
    • (2009) Reprod. Biol. Endocrinol , vol.7 , pp. 45
    • Alekseev, O.M.1    Richardson, R.T.2    Alekseev, O.3    O'Rand, M.G.4
  • 67
    • 58749113430 scopus 로고    scopus 로고
    • A three-dimensional view of the molecular machinery of RNA interference
    • Jinek M, Doudna JA. 2009. A three-dimensional view of the molecular machinery of RNA interference. Nature 457:405-412.
    • (2009) Nature , vol.457 , pp. 405-412
    • Jinek, M.1    Doudna, J.A.2
  • 68
    • 77955644289 scopus 로고    scopus 로고
    • Mammalian microRNAs predominantly act to decrease target mRNA levels
    • Guo H, Ingolia NT, Weissman JS, Bartel DP. 2010. Mammalian microRNAs predominantly act to decrease target mRNA levels. Nature 466:835-840.
    • (2010) Nature , vol.466 , pp. 835-840
    • Guo, H.1    Ingolia, N.T.2    Weissman, J.S.3    Bartel, D.P.4
  • 70
    • 23944506789 scopus 로고    scopus 로고
    • Animal virus replication and RNAi-mediated antiviral silencing in Caenorhabditis elegans
    • Lu R, Maduro M, Li F, Li HW, Broitman-Maduro G, Li WX, Ding SW. 2005. Animal virus replication and RNAi-mediated antiviral silencing in Caenorhabditis elegans. Nature 436:1040-1043.
    • (2005) Nature , vol.436 , pp. 1040-1043
    • Lu, R.1    Maduro, M.2    Li, F.3    Li, H.W.4    Broitman-Maduro, G.5    Li, W.X.6    Ding, S.W.7
  • 71
    • 67651019034 scopus 로고    scopus 로고
    • Caenorhabditis elegans genomic response to soil bacteria predicts environmentspecific genetic effects on life history traits
    • doi: 101371/journal.pgen.1000503.
    • Coolon JD, Jones KL, Todd TC, Carr BC, Herman MA. 2009. Caenorhabditis elegans genomic response to soil bacteria predicts environmentspecific genetic effects on life history traits. PLoS Genet. 5:e1000503. doi: 10.1371/journal.pgen.1000503.
    • (2009) PLoS Genet , vol.5 , pp. 1000503
    • Coolon, J.D.1    Jones, K.L.2    Todd, T.C.3    Carr, B.C.4    Herman, M.A.5
  • 72
    • 10344259636 scopus 로고    scopus 로고
    • Isolation of mutations with dumpy-like phenotypes and of collagen genes in the nematode Pristionchus pacificus
    • Kenning C, Kipping I, Sommer RJ. 2004. Isolation of mutations with dumpy-like phenotypes and of collagen genes in the nematode Pristionchus pacificus. Genesis 40:176-183.
    • (2004) Genesis , vol.40 , pp. 176-183
    • Kenning, C.1    Kipping, I.2    Sommer, R.J.3
  • 74
    • 84861679962 scopus 로고    scopus 로고
    • Genomic analysis of immune response against Vibrio cholerae hemolysin in Caenorhabditis elegans
    • doi:101371/journal.pone.0038200
    • Sahu SN, Lewis J, Patel I, Bozdag S, Lee JH, LeClerc JE, Cinar HN. 2012. Genomic analysis of immune response against Vibrio cholerae hemolysin in Caenorhabditis elegans. PLoS One 7:e38200. doi:10.1371/journal.pone.0038200.
    • (2012) PLoS One , vol.7 , pp. 38200
    • Sahu, S.N.1    Lewis, J.2    Patel, I.3    Bozdag, S.4    Lee, J.H.5    LeClerc, J.E.6    Cinar, H.N.7
  • 78
    • 77958497213 scopus 로고    scopus 로고
    • Heads up! How the intestinal epithelium safeguards mucosal barrier immunity through the inflammasome and beyond.
    • Cario E. 2010. Heads up! How the intestinal epithelium safeguards mucosal barrier immunity through the inflammasome and beyond. Curr. Opin. Gastroenterol. 26:583-590.
    • (2010) Curr. Opin. Gastroenterol. , vol.26 , pp. 583-590
    • Cario, E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.