Soluble polysialylated NCAM: A novel player of the innate immune system in the lung

Cellular and Molecular Life Sciences

Volumn 70, Issue 19, 2013, Pages 3695-3708

  Ulm, Christina ^a   Saffarzadeh, Mona ^a   Mahavadi, Poornima ^a   Müller, Sandra ^a   Prem, Gerlinde ^a   Saboor, Farhan ^a   Simon, Peter ^a   Middendorff, Ralf ^a   Geyer, Hildegard ^a   Henneke, Ingrid ^a   Bayer, Nils ^a   Rinné, Susanne ^b   Lütteke, Thomas ^a   Böttcher Friebertshäuser, Eva ^b   Gerardy Schahn, Rita ^c   Schwarzer, David ^c   Mühlenhoff, Martina ^c   Preissner, Klaus T ^a   Günther, Andreas ^a   Geyer, Rudolf ^a   Galuska, Sebastian P ^a   more..

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

^b PHILIPPS UNIVERSITY MARBURG   (Germany)

^c HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

COPD; Innate immune system; Lung; NCAM; Polysialic acid

Indexed keywords

BLEOMYCIN; DNA; HISTONE; INFLAMMASOME; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; METALLOPROTEINASE; NERVE CELL ADHESION MOLECULE; POLYSIALYLATED NERVE CELL ADHESION MOLECULE; UNCLASSIFIED DRUG;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COMPARTMENTALIZATION; CELL CULTURE; CELL PROTECTION; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOTOXICITY; EPITHELIUM CELL; FEMALE; FETUS LUNG MATURATION; HUMAN; HUMAN CELL; HUMAN TISSUE; INFLAMMATION; INNATE IMMUNITY; LUNG; LUNG ALVEOLUS EPITHELIUM; LUNG DISEASE; LUNG FIBROSIS; LUNG HOMOGENATE; LUNG PARENCHYMA; MALE; MOUSE; NONHUMAN; PROTEIN PROCESSING; TRANS GOLGI NETWORK; UPREGULATION;

EID: 84884357123     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-013-1342-0     Document Type: Article

References (68)

1. Rutishauser U (2008) Polysialic acid in the plasticity of the developing and adult vertebrate nervous system. Nat Rev Neurosci 9(1):26-35
2. Hildebrandt H, Muhlenhoff M, Weinhold B, Gerardy-Schahn R (2007) Dissecting polysialic acid and NCAM functions in brain development. J Neurochem 103(Suppl 1):56-64
3. Lackie PM, Zuber C, Roth J (1990) Polysialic acid and N-CAM localisation in embryonic rat kidney: mesenchymal and epithelial elements show different patterns of expression. Development 110(3):933-947
4. Lackie PM, Zuber C, Roth J (1991) Expression of polysialylated N-CAM during rat heart development. Differentiation 47(2):85-98
5. Lackie PM, Zuber C, Roth J (1994) Polysialic acid of the neural cell adhesion molecule (N-CAM) is widely expressed during organogenesis in mesodermal and endodermal derivatives. Differentiation 57(2):119-131
6. Galuska SP, Geyer R, Gerardy-Schahn R, Muhlenhoff M, Geyer H (2008) Enzyme-dependent variations in the polysialylation of the neural cell adhesion molecule (NCAM) in vivo. J Biol Chem 283(1):17-28
7. Galuska SP et al (2006) Polysialic acid profiles of mice expressing variant allelic combinations of the polysialyltransferases ST8SiaII and ST8SiaIV. J Biol Chem 281(42):31605-31615
8. Colley KJ (2010) Structural basis for the polysialylation of the neural cell adhesion molecule. Adv Exp Med Biol 663:111-126
9. Rutishauser U (1998) Polysialic acid at the cell surface: biophysics in service of cell interactions and tissue plasticity. J Cell Biochem 70(3):304-312
10. Yabe U, Sato C, Matsuda T, Kitajima K (2003) Polysialic acid in human milk. CD36 is a new member of mammalian polysialic acid-containing glycoprotein. J Biol Chem 278(16):13875-13880
11. Zuber C, Lackie PM, Catterall WA, Roth J (1992) Polysialic acid is associated with sodium channels and the neural cell adhesion molecule N-CAM in adult rat brain. J Biol Chem 267(14):9965-9971
12. Galuska SP et al (2010) Synaptic cell adhesion molecule SynCAM 1 is a target for polysialylation in postnatal mouse brain. Proc Natl Acad Sci USA 107(22):10250-10255
13. Curreli S, Arany Z, Gerardy-Schahn R, Mann D, Stamatos NM (2007) Polysialylated neuropilin-2 is expressed on the surface of human dendritic cells and modulates dendritic cell-T lymphocyte interactions. J Biol Chem 282:30346-30356
14. Weinhold B et al (2005) Genetic ablation of polysialic acid causes severe neurodevelopmental defects rescued by deletion of the neural cell adhesion molecule. J Biol Chem 280(52):42971-42977
15. Rey-Gallardo A, Delgado-Martin C, Gerardy-Schahn R, Rodriguez-Fernandez JL, Vega MA (2011) Polysialic acid is required for neuropilin-2a/b-mediated control of CCL21-driven chemotaxis of mature dendritic cells and for their migration in vivo. Glycobiology 21(5):655-662
16. Rey-Gallardo A et al (2010) Polysialylated neuropilin-2 enhances human dendritic cell migration through the basic C-terminal region of CCL21. Glycobiology 20(9):1139-1146
17. Drake PM et al (2008) Polysialic acid, a glycan with highly restricted expression, is found on human and murine leukocytes and modulates immune responses. J Immunol 181(10):6850-6858
18. Drake PM et al (2009) Polysialic acid governs T-cell development by regulating progenitor access to the thymus. Proc Natl Acad Sci USA 106(29):11995-12000
19. Husmann M, Pietsch T, Fleischer B, Weisgerber C, Bitter-Suermann D (1989) Embryonic neural cell adhesion molecules on human natural killer cells. Eur J Immunol 19(9):1761-1763
20. Moebius JM, Widera D, Schmitz J, Kaltschmidt C, Piechaczek C (2007) Impact of polysialylated CD56 on natural killer cell cytotoxicity. BMC Immunol 8:13
21. Lantuejoul S et al (2000) NCAM (neural cell adhesion molecules) expression in malignant mesotheliomas. Hum Pathol 31(4):415-421
22. Hirn M, Pierres M, Deagostini-Bazin H, Hirsch M, Goridis C (1981) Monoclonal antibody against cell surface glycoprotein of neurons. Brain Res 214(2):433-439
23. Frosch M, Gorgen I, Boulnois GJ, Timmis KN, Bitter-Suermann D (1985) NZB mouse system for production of monoclonal antibodies to weak bacterial antigens: isolation of an IgG antibody to the polysaccharide capsules of Escherichia coli K1 and group B meningococci. Proc Natl Acad Sci USA 82(4):1194-1198
24. Stummeyer K, Dickmanns A, Muhlenhoff M, Gerardy-Schahn R, Ficner R (2005) Crystal structure of the polysialic acid-degrading endosialidase of bacteriophage K1F. Nat Struct Mol Biol 12(1):90-96
25. Eswar N et al (2006) Comparative protein structure modeling using Modeller. Curr Protoc Bioinforma (chapter 5: unit 5.6)
26. Berman H, Henrick K, Nakamura H (2003) Announcing the worldwide Protein Data Bank. Nat Struct Biol 10(12):980
27. Altschul SF, Gish W, Miller W, Myers EW, Lipman DJ (1990) Basic local alignment search tool. J Mol Biol 215(3):403-410
28. Bohne A, Lang E, von der Lieth CW (1999) SWEET - WWW-based rapid 3D construction of oligo- and polysaccharides. Bioinformatics 15(9):767-768
29. Bohne-Lang A, von der Lieth CW (2005) GlyProt: in silico glycosylation of proteins. Nucleic Acids Res 33(Web Server issue):W214-219
30. Lütteke T et al (2006) GLYCOSCIENCES.de: an Internet portal to support glycomics and glycobiology research. Glycobiology 16(5):71R-81R
31. Krieger E et al (2009) Improving physical realism, stereochemistry, and side-chain accuracy in homology modeling: four approaches that performed well in CASP8. Proteins 77(Suppl 9):114-122
32. Duan Y et al (2003) A point-charge force field for molecular mechanics simulations of proteins based on condensed-phase quantum mechanical calculations. J Comput Chem 24(16):1999-2012
33. Roepstorff P, Fohlman J (1984) Proposal for a common nomenclature for sequence ions in mass spectra of peptides. Biomed Mass Spectrom 11(11):601
34. Inoue S, Lin SL, Lee YC, Inoue Y (2001) An ultrasensitive chemical method for polysialic acid analysis. Glycobiology 11(9):759-767
35. Saffarzadeh M et al (2012) Neutrophil extracellular traps directly induce epithelial and endothelial cell death: a predominant role of histones. PLoS One 7(2):e32366
36. Haselhorst T et al (2006) Endosialidase NF appears to bind polySia DP5 in a helical conformation. Chembiochem 7(12):1875-1877
37. Schwarzer D et al (2009) Proteolytic release of the intramolecular chaperone domain confers processivity to endosialidase F. J Biol Chem 284(14):9465-9474
38. Kleene R, Schachner M (2004) Glycans and neural cell interactions. Nat Rev Neurosci 5(3):195-208
39. Isomura R, Kitajima K, Sato C (2011) Structural and functional impairments of polysialic acid by a mutated polysialyltransferase found in schizophrenia. J Biol Chem 286(24):21535-21545
40. Chung KF (2001) Cytokines in chronic obstructive pulmonary disease. Eur Respir J Suppl 34:50s-59s
41. van Eeden SF, Yeung A, Quinlam K, Hogg JC (2005) Systemic response to ambient particulate matter: relevance to chronic obstructive pulmonary disease. Proc Am Thorac Soc 2(1):61-67
42. Rusznak C et al (2000) Effect of cigarette smoke on the permeability and IL-1beta and sICAM-1 release from cultured human bronchial epithelial cells of never-smokers, smokers, and patients with chronic obstructive pulmonary disease. Am J Respir Cell Mol Biol 23(4):530-536
43. Doz E et al (2008) Cigarette smoke-induced pulmonary inflammation is TLR4/MyD88 and IL-1R1/MyD88 signaling dependent. J Immunol 180(2):1169-1178
44. Grande NR, Peao MND, Sa CMd, Aguas AP (1998) Lung fibrosis induced by bleomycin: structural changes and overview of recent advances. Scan Microsc 12(3):487-494
45. Gasse P et al (2007) IL-1R1/MyD88 signaling and the inflammasome are essential in pulmonary inflammation and fibrosis in mice. J Clin Invest 117(12):3786-3799
46. Parker D, Prince A (2011) Innate immunity in the respiratory epithelium. Am J Respir Cell Mol Biol 45(2):189-201
47. Van Wetering S et al (1997) Effect of defensins on interleukin-8 synthesis in airway epithelial cells. Am J Physiol 272(5 Pt 1):L888-L896
48. Phung TT et al (2011) Key role of regulated upon activation normal T-cell expressed and secreted, nonstructural protein1 and myeloperoxidase in cytokine storm induced by influenza virus PR-8 (A/H1N1) infection in A549 bronchial epithelial cells. Microbiol Immunol 55(12):874-884
49. Secher T (2010) Soluble NCAM. Adv Exp Med Biol 663:227-242
50. Bock E et al (1987) Characterization of soluble forms of NCAM. FEBS Lett 225(1-2):33-36
51. Bork K, Reutter W, Gerardy-Schahn R, Horstkorte R (2005) The intracellular concentration of sialic acid regulates the polysialylation of the neural cell adhesion molecule. FEBS Lett 579(22):5079-5083
52. Du J et al (2009) Metabolic glycoengineering: sialic acid and beyond. Glycobiology 19(12):1382-1401
53. Saetta M et al (2000) Goblet cell hyperplasia and epithelial inflammation in peripheral airways of smokers with both symptoms of chronic bronchitis and chronic airflow limitation. Am J Respir Crit Care Med 161(3 Pt 1):1016-1021
54. Seok J et al (2013) Genomic responses in mouse models poorly mimic human inflammatory diseases. Proc Natl Acad Sci USA 110(9):3507-3512
55. Heijink IH et al (2011) Role of aberrant metalloproteinase activity in the pro-inflammatory phenotype of bronchial epithelium in COPD. Respir Res 12:110
56. Kalus I, Bormann U, Mzoughi M, Schachner M, Kleene R (2006) Proteolytic cleavage of the neural cell adhesion molecule by ADAM17/TACE is involved in neurite outgrowth. J Neurochem 98(1):78-88
57. Grommes J, Soehnlein O (2010) Contribution of neutrophils to acute lung injury. Mol Med 17(3-4):293-307
58. Brinkmann V et al (2004) Neutrophil extracellular traps kill bacteria. Science 303(5663):1532-1535
59. Fuchs TA, Bhandari AA, Wagner DD (2011) Histones induce rapid and profound thrombocytopenia in mice. Blood 118(13):3708-3714
60. Xu J et al (2009) Extracellular histones are major mediators of death in sepsis. Nat Med 15(11):1318-1321
61. Crocker PR (2005) Siglecs in innate immunity. Curr Opin Pharmacol 5(4):431-437
62. Crocker PR, Paulson JC, Varki A (2007) Siglecs and their roles in the immune system. Nat Rev Immunol 7(4):255-266
63. Wang Y, Neumann H (2010) Alleviation of neurotoxicity by microglial human Siglec-11. J Neurosci 30(9):3482-3488
64. Villanueva E et al (2011) Netting neutrophils induce endothelial damage, infiltrate tissues, and expose immunostimulatory molecules in systemic lupus erythematosus. J Immunol 187(1):538-552
65. Marcos V et al (2010) CXCR2 mediates NADPH oxidase-independent neutrophil extracellular trap formation in cystic fibrosis airway inflammation. Nat Med 16(9):1018-1023
66. Hakkim A et al (2010) Impairment of neutrophil extracellular trap degradation is associated with lupus nephritis. Proc Natl Acad Sci USA 107(21):9813-9818
67. Fuchs TA, Brill A, Wagner DD (2012) Neutrophil extracellular trap impact on deep vein thrombosis. Arterioscler Thromb Vasc Biol 32(8):1777-1783
68. Caudrillier A et al (2012) Platelets induce neutrophil extracellular traps in transfusion-related acute lung injury. J Clin Invest 122(7):2661-2671