Effect of defensins on interleukin-8 synthesis in airway epithelial cells

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 272, Issue 5 16-5, 1997, Pages

  Van Wetering, Sandra ^a   Mannesse Lazeroms, Sylvia P G ^a   Van Sterkenburg, Marianne A J A ^a   Daha, Mohamed R ^a   Dijkman, Joop H ^a   Hiemstra, Pieter S ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Airway epithelium; Chemokines; Inflammation; Neutrophils

Indexed keywords

CHEMOKINE; DEFENSIN; INTERLEUKIN 8; LEUKOCYTE ELASTASE;

ARTICLE; EPITHELIUM CELL; GENE EXPRESSION; HUMAN; HUMAN CELL; INFLAMMATION; NEUTROPHIL; NEUTROPHIL CHEMOTAXIS; PRIORITY JOURNAL; PROTEIN PURIFICATION; PROTEIN SECRETION; RESPIRATORY EPITHELIUM; TISSUE INJURY;

EID: 0030995527     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.1997.272.5.l888     Document Type: Article

References (32)

1. Baggiolini, M., B. Dewald, and B. Moser. Interleukin-8 and related chemotactic cytokines. CXC and CC chemokines. Adv. Immunol. 55: 97-179, 1994.
2. Bédard, M., C. D. McClure, N. L. Schiller, C. Francoeur, A. Cantin, and M. Denis. Release of interleukin-8, interleukin 6, and colony-stimulating factors by upper airway epithelial cells: implications for cystic fibrosis. Am. J. Respir. Cell Mol. Biol. 9: 455-462, 1993.
3. Bosco, M. C., L. Guseela, I. Espinoza-Delgado, D. L. Lomgo, and L. Varesio. Interferon-γ upregulates interleukin-8 gene expression in human monocytic cells by a posttranscriptional mechanism. Blood 83: 537-542, 1994.
4. Chertov, O., D. F. Michiel, L. Xu, J. M. Wang, K. Tani, W. J. Murphy, D. L. Longo, D. D. Taub, and J. J. Oppenheim. Identification of defensin-1, defensin-2 and cap37/ azurocidin as T-cell chemoattractant proteins released from interleukin-8 stimulated neutrophils. J. Biol. Chem. 271: 2935-2940, 1996.
5. Chomczynski, P., and N. Sacchi. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162: 156-159, 1987.
6. Davies, R. J. Airway epithelial cells and mediators of inflammation. Respir. Med. 87: 405-408, 1993.
7. De Jong, P. M., M. A. J. A. Van Sterkenburg, J. A. Kempenaar, J. H. Dijkman, and M. Ponec. Serial culturing of human bronchial epithelial cells derived from biopsies. In Vitro Cell. Dev. Biol. 29A: 379-387, 1993.
8. Ganz, T. Extracellular release of antimicrobial defensins by human polymorphonuclear leukocytes. Infect. Immun. 55: 568-571, 1987.
9. Ganz, T., M. E. Selsted, D. Szklarek, S. S. L. Harwig, K. Daher, D. F. Bainton, and R. I. Lehrer. Defensins. Natural peptide antibiotics of human neutrophils. J. Clin. Invest. 76: 1427-1435, 1985.
10. Gerritsma, J. S. J., P. S. Hiemstra, A. F. Gerritsen, W. Prodjosujadi, C. L. Verweij, L. A. Van Es, and M. R. Daha. Regulation and production of interleukin-8 by human proximal tubular epithelial cells in vitro. Clin. Exp. Immunol. 103: 289-294, 1995.
11. Hack, C. E., M. Hart, R. J. M. Strack Van Schijndel, A. J. M. Eerenberg, J. H. Nuijens, L. G. Thijs, and L. A. Aarden. Interleukin-8 in sepsis: relation to shock and inflammatory mediators. Infect. Immun. 60: 2835-2842, 1992.
12. Harwig, S. S. L., T. Ganz, and R. I. Lehrer. Neutrophil defensins: purification, characterization, and antimicrobial testing. Methods Enzymol. 236: 160-172, 1995.
13. Harwig, S. S. L., A. S. K. Park, and R. I. Lehrer. Characterization of defensin precursors in mature human neutrophils. Blood 79: 1532-1537, 1992.
14. Ivey, C. L., F. M. Williams, P. D. Collins, P. J. Jose, and T. J. Williams. Neutrophil chemoattractants generated in two phases during reperfusion of ischemic myocardium in the rabbit. J. Clin. Invest. 95: 2720-2728, 1995.
15. Khair, O. A., J. L. Devalia, M. M. Abdelaziz, R. J. Sapsford, H. Tarraf, and R. J. Davies. Effect of Haemophilus influenzae endotoxin on the synthesis of IL-6, IL-8, TNF-α and expression of ICAM-1 in cultured human bronchial epithelial cells. Eur. Respir. J. 7: 2109-2116, 1994.
16. Koenderman, L., P. T. M. Kok, M. L. Hamelink, A. J. Verhoeven, and P. L. B. Bruijnzeel. An improved method for the isolation of eosinophilic granulocytes from peripheral blood of normal individuals. J. Leukoc. Biol. 44: 79-86, 1988.
17. Kunkel, S. L., T. J. Standiford, K. Kasahara, and R. M. Strieter. Interleukin-8 (IL-8): the major neutrophil chemotactic factor in the lung. Exp. Lung Res. 17: 17-23, 1991.
18. Lehrer, R. I., A. K. Lichtenstein, and T. Ganz. Defensins: antimicrobial and cytotoxic peptides of mammalian cells. Annu. Rev. Immunol. 11: 105-128, 1993.
19. Lichtenstein, A. K. Mechanism of mammalian cell lysis mediated by peptide defensins. Evidence for an initial alteration of the plasma membrane. J. Clin. Invest. 88: 93-100, 1991.
20. Lichtenstein, A. K., T. Ganz, T. M. Nguyen, M. E. Selsted, and R. I. Lehrer. Mechanism of target cytolysis by peptide defensins. Target cell metabolic activities, possibly involving endocytosis, are crucial for expression of cytotoxicity. J. Immunol. 140: 2686-2694, 1988.
21. Liebler, J. M., S. L. Kunkel, M. D. Burdick, T. J. Standiford, M. W. Rolfe, and R. M. Strieter. Production of IL-8 and monocyte chemotactic peptide-1 by peripheral blood monocytes. Disparate responses to phytohemagglutinin and lipopolysaccharide. J. Immunol. 152: 241-249, 1994.
22. Misuno, N. I., T. S. Kolesnikova, R. I. Lehrer, T. Ganz, and N. N. Voitenok. Effect of HNP-1 of human neutrophils on production of tumor necrosis factor a by human blood monocytes in vitro. Bull. Exp. Biol. Med. 113: 709-712, 1992.
23. Murphy, C. J., B. A. Foster, M. J. Mannis, M. E. Selsted, and T. W. Reid. Defensins are mitogenic for epithelial cells and fibroblasts. J. Cell. Physiol. 155: 408-413, 1993.
24. Nakamura, H., K. Yoshimura, H. A. Jaffe, and R. G. Crystal. Interleukin-8 gene expression in human bronchial epithelial cells. J. Biol. Chem. 266: 19611-19617, 1991.
25. Nakamura, H., K. Yoshimura, N. G. McElvaney, and R. G. Crystal. Neutrophil elastase in respiratory epithelial lining fluid of individuals with cystic fibrosis induces interleukin-8 gene expression in a human bronchial epithelial cell line. J. Clin. Invest. 89: 1478-1484, 1992.
26. Okrent, D. G., A. K. Lichtenstein, and T. Ganz. Direct cytotoxicity of polymorphonuclear leukocyte granule proteins to human lung-derived cells and endothelial cells. Am. Rev. Respir. Dis. 141: 179-185, 1990.
27. Oppenheim, J. J., and C. O. C. Zachariae. Properties of the novel proinflammatory supergene "intercrine" cytokine family. Annu. Rev. Immunol. 9: 617-648, 1991.
28. Panyutich, A. V., P. S. Hiemstra, S. Van Wetering, and T. Ganz. Human neutrophil defensin and serpins form complexes and inactivate each other. Am. J. Respir. Cell Mol. Biol. 12: 351-357, 1995.
29. Panyutich, A. V., E. A. Panyutich, A. Krapivin, and E. A. Baturevich, T. Ganz. Plasma defensin concentrations are elevated in patients with septicemia and bacterial meningitis. J. Lab. Clin. Med. 122: 202-207, 1993.
30. Richman-Eisenstat, J., P. G. Jorens, C. A. Hébert, I. Ueki, and J. A. Nadel. Interleukin-8: an important chemoattractant in sputum of patients with chronic inflammatory diseases. Am. J. Physiol. 264 (Lung Cell. Mol. Physiol. 8): L413-L418, 1993.
31. Sibille, Y., and F. Marchandise. Pulmonary immune cells in health and disease: polymorphonuclear neutrophils. Eur. Respir. J. 6: 1529-1543, 1993.
32. Standiford, T. J., S. L. Kunkel, M. A. Basha, S. W. Chensue, J. P. Lynch III, G. B. Toews, J. Westwick, and R. M. Strieter. Interleukin-8 gene expression by a pulmonary epithelial cell line. A model for cytokine networks in the lung. J. Clin. Invest. 86: 1945-1953, 1990.