Siglecs in innate immunity

Current Opinion in Pharmacology

Volumn 5, Issue 4 SPEC. ISS., 2005, Pages 431-437

  Crocker, Paul R ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CD22 ANTIGEN; CD33 ANTIGEN; CELL RECEPTOR; IMMUNOGLOBULIN; LIGAND; PROTEIN KINASE SYK; PROTEIN KINASE ZAP 70; PROTEIN SH2; SIALIC ACID BINDING IMMUNOGLOBULIN LIKE LECTIN; UNCLASSIFIED DRUG;

ACUTE GRANULOCYTIC LEUKEMIA; APOPTOSIS; B LYMPHOCYTE ACTIVATION; BACTERIAL INFECTION; CELL ADHESION; CYTOKINE PRODUCTION; DRUG TARGETING; HOST RESISTANCE; HUMAN; IMMUNOREGULATION; INNATE IMMUNITY; KNOCKOUT MOUSE; MACROPHAGE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVIEW; SIGNAL TRANSDUCTION; VIRUS INFECTION;

EID: 21644463169     PISSN: 14714892     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.coph.2005.03.003     Document Type: Review

References (51)

1. A.P. May R.C. Robinson M. Vinson P.R. Crocker E.Y. Jones Crystal structure of the N-terminal domain of sialoadhesin in complex with 3′ sialyllactose at 1.85 A resolution Mol Cell 1 1998 719-728
2. M.S. Alphey H. Attrill P.R. Crocker D.M. van Aalten High resolution crystal structures of Siglec-7. Insights into ligand specificity in the Siglec family J Biol Chem 278 2003 3372-3377
3. S. Kelm A. Pelz R. Schauer M.T. Filbin S. Tang M.E. Debellard R.L. Schnaar J.A. Mahoney A. Hartnell P. Bradfield et al. Sialoadhesin, myelin-associated glycoprotein and CD22 define a new family of sialic acid-dependent adhesion molecules of the immunoglobulin superfamily Curr Biol 4 1994 965-972
4. P.R. Crocker Siglecs: Sialic-acid-binding immunoglobulin-like lectins in cell-cell interactions and signalling Curr Opin Struct Biol 12 2002 609-615
5. P.R. Crocker A. Varki Siglecs, sialic acids and innate immunity Trends Immunol 22 2001 337-342
6. T. Angata E.H. Margulies E.D. Green A. Varki Large-scale sequencing of the CD33-related Siglec gene cluster in five mammalian species reveals rapid evolution by multiple mechanisms Proc Natl Acad Sci USA 101 2004 13251-13256
7. M. Viau M. Zouali B-lymphocytes, innate immunity, and autoimmunity Clin Immunol 114 2005 17-26
8. K. Lock J. Zhang J. Lu S.H. Lee P.R. Crocker Expression of CD33-related siglecs on human mononuclear phagocytes, monocyte-derived dendritic cells and plasmacytoid dendritic cells Immunobiology 209 2004 199-207
9. J.Q. Zhang B. Biedermann L. Nitschke P.R. Crocker The murine inhibitory receptor mSiglec-E is expressed broadly on cells of the innate immune system whereas mSiglec-F is restricted to eosinophils Eur J Immunol 34 2004 1175-1184
10. C. Jones M. Virji P.R. Crocker Recognition of sialylated meningococcal lipopolysaccharide by siglecs expressed on myeloid cells leads to enhanced bacterial uptake Mol Microbiol 49 2003 1213-1225
11. J.L. Sonnenburg T.K. Altheide A. Varki A uniquely human consequence of domain-specific functional adaptation in a sialic acid-binding receptor Glycobiology 14 2004 339-346
12. P. Gagneux A. Varki Evolutionary considerations in relating oligosaccharide diversity to biological function Glycobiology 9 1999 747-755
13. J.V. Ravetch L.L. Lanier Immune inhibitory receptors Science 290 2000 84-89
14. E. Nutku H. Aizawa S.A. Hudson B.S. Bochner Ligation of Siglec-8: A selective mechanism for induction of human eosinophil apoptosis Blood 101 2003 5014-5020
15. L. Balaian E.D. Ball Anti-CD33 monoclonal antibodies enhance the cytotoxic effects of cytosine arabinoside and idarubicin on acute myeloid leukemia cells through similarities in their signaling pathways Exp Hematol 33 2005 199-211
16. L. Balaian R.K. Zhong E.D. Ball The inhibitory effect of anti-CD33 monoclonal antibodies on AML cell growth correlates with Syk and/or ZAP-70 expression Exp Hematol 31 2003 363-371
17. C.L. Erickson-Miller S.D. Freeman C.B. Hopson K.J. DAlessio E.I. Fischer K.K. Kikly J.A. Abrahamson S.D. Holmes A.G. King Characterization of Siglec-5 (CD170) expression and functional activity of anti-Siglec-5 antibodies on human phagocytes Exp Hematol 31 2003 382-388
18. F. Lajaunias J.M. Dayer C. Chizzolini Constitutive repressor activity of CD33 on human monocytes requires sialic acid recognition and phosphoinositide 3-kinase-mediated intracellular signaling Eur J Immunol 35 2005 243-251
19. T. Ulyanova J. Blasioli T.A. Woodford-Thomas M.L. Thomas The sialoadhesin CD33 is a myeloid-specific inhibitory receptor Eur J Immunol 29 1999 3440-3449
20. S.P. Paul L.S. Taylor E.K. Stansbury D.W. McVicar Myeloid specific human CD33 is an inhibitory receptor with differential ITIM function in recruiting the phosphatases SHP-1 and SHP-2 Blood 96 2000 483-490
21. T. Avril H. Floyd F. Lopez E. Vivier P.R. Crocker The membrane-proximal immunoreceptor tyrosine-based inhibitory motif is critical for the inhibitory signaling mediated by siglecs-7 and -9, CD33-related siglecs expressed on human monocytes and NK cells J Immunol 173 2004 6841-6849
22. C.S. Navara The spleen tyrosine kinase (Syk) in human disease, implications for design of tyrosine kinase inhibitor based therapy Curr Pharm Des 10 2004 1739-1744
23. J. Chen P.A. McLean B.G. Neel G. Okunade G.E. Shull H.H. Wortis CD22 attenuates calcium signaling by potentiating plasma membrane calcium-ATPase activity Nat Immunol 5 2004 651-657
24. E.C. Brinkman-Van der Linden T. Angata S.A. Reynolds L.D. Powell S.M. Hedrick A. Varki CD33/Siglec-3 binding specificity, expression pattern, and consequences of gene deletion in mice Mol Cell Biol 23 2003 4199-4206
25. B.E. Collins O. Blixt A.R. DeSieno N. Bovin J.D. Marth J.C. Paulson Masking of CD22 by cis ligands does not prevent redistribution of CD22 to sites of cell contact Proc Natl Acad Sci USA 101 2004 6104-6109
26. J.C. Poe Y. Fujimoto M. Hasegawa K.M. Haas A.S. Miller I.G. Sanford C.B. Bock M. Fujimoto T.F. Tedder CD22 regulates B lymphocyte function in vivo through both ligand-dependent and ligand-independent mechanisms Nat Immunol 5 2004 1078-1087
27. J.D. Marth Unmasking connections in transmembrane immune signaling Nat Immunol 5 2004 1008-1010
28. S. Kelm J. Gerlach R. Brossmer C.P. Danzer L. Nitschke The ligand-binding domain of CD22 is needed for inhibition of the B cell receptor signal, as demonstrated by a novel human CD22-specific inhibitor compound J Exp Med 195 2002 1207-1213
29. L. Jin P.A. McLean B.G. Neel H.H. Wortis Sialic acid binding domains of CD22 are required for negative regulation of B cell receptor signaling J Exp Med 195 2002 1199-1205
30. G. Nicoll T. Avril K. Lock K. Furukawa N. Bovin P.R. Crocker Ganglioside GD3 expression on target cells can modulate NK cell cytotoxicity via siglec-7-dependent and -independent mechanisms Eur J Immunol 33 2003 1642-1648
31. Y. Ikehara S.K. Ikehara J.C. Paulson Negative regulation of T cell receptor signaling by Siglec-7 (p70/AIRM) and Siglec-9 J Biol Chem 279 2004 43117-43125
32. T. Yamaji M. Mitsuki T. Teranishi Y. Hashimoto Characterization of inhibitory signaling motifs of the natural killer cell receptor Siglec-7: Attenuated recruitment of phosphatases by the receptor is attributed to two amino acids in the motifs Glycobiology 2005
33. N. Vanderheijden P.L. Delputte H.W. Favoreel J. Vandekerckhove J. Van Damme P.A. van Woensel H.J. Nauwynck Involvement of sialoadhesin in entry of porcine reproductive and respiratory syndrome virus into porcine alveolar macrophages J Virol 77 2003 8207-8215
34. P.L. Delputte H.J. Nauwynck Porcine arterivirus infection of alveolar macrophages is mediated by sialic acid on the virus J Virol 78 2004 8094-8101
35. M.L. Linenberger CD33-directed therapy with gemtuzumab ozogamicin in acute myeloid leukemia: Progress in understanding cytotoxicity and potential mechanisms of drug resistance Leukemia 19 2005 176-182
36. J.S. Bonifacino L.M. Traub Signals for sorting of transmembrane proteins to endosomes and lysosomes Annu Rev Biochem 72 2003 395-447
37. R.B. Walter B.W. Raden D.M. Kamikura J.A. Cooper I.D. Bernstein Influence of CD33 expression levels and ITIM-dependent internalization on gemtuzumab ozogamicin-induced cytotoxicity Blood 105 2005 1295-1302
38. C. Galustian C.G. Park W. Chai M. Kiso S.A. Bruening Y.S. Kang R.M. Steinman T. Feizi High and low affinity carbohydrate ligands revealed for murine SIGN-R1 by carbohydrate array and cell binding approaches, and differing specificities for SIGN-R3 and langerin Int Immunol 16 2004 853-866
39. B.S. Bochner R.A. Alvarez P. Mehta N.V. Bovin O. Blixt J.R. White R.L. Schnaar Glycan array screening reveals a candidate ligand for siglec-8 J Biol Chem 280 2005 4307-4312
40. O. Blixt S. Head T. Mondala C. Scanlan M.E. Huflejt R. Alvarez M.C. Bryan F. Fazio D. Calarese J. Stevens et al. Printed covalent glycan array for ligand profiling of diverse glycan binding proteins Proc Natl Acad Sci USA 101 2004 17033-17038
41. S. Kelm R. Brossmer R. Isecke H.J. Gross K. Strenge R. Schauer Functional groups of sialic acids involved in binding to siglecs (sialoadhesins) deduced from interactions with synthetic analogues Eur J Biochem 255 1998 663-672
42. K.M. Halkes P.M. St Hilaire P.R. Crocker M. Meldal Glycopeptides as oligosaccharide mimics: High affinity sialopeptide ligands for sialoadhesin from combinatorial libraries J Comb Chem 5 2003 18-27
43. N.R. Zaccai K. Maenaka T. Maenaka P.R. Crocker R. Brossmer S. Kelm E.Y. Jones Structure-guided design of sialic acid-based siglec inhibitors and crystallographic analysis in complex with sialoadhesin Structure (Camb) 11 2003 557-567
44. J.T. Bukrinsky P.M. St Hilaire M. Meldal P.R. Crocker A. Henriksen Complex of sialoadhesin with a glycopeptide ligand Biochim Biophys Acta 1702 2004 173-179
45. M. Zhang A. Varki Cell surface sialic acids do not affect primary CD22 interactions with CD45 and surface IgM nor the rate of constitutive CD22 endocytosis Glycobiology 14 2004 939-949
46. A. Hartnell J. Steel H. Turley M. Jones D.G. Jackson P.R. Crocker Characterization of human sialoadhesin, a sialic acid binding receptor expressed by resident and inflammatory macrophage populations Blood 97 2001 288-296
47. Y. Kumamoto N. Higashi K. Denda-Nagai M. Tsuiji K. Sato P.R. Crocker T. Irimura Identification of sialoadhesin as a dominant lymph node counter-receptor for mouse macrophage galactose-type C-type lectin 1 J Biol Chem 279 2004 49274-49280
48. M. Falco R. Biassoni C. Bottino M. Vitale S. Sivori R. Augugliaro L. Moretta A. Moretta Identification and molecular cloning of p75/AIRM1, a novel member of the sialoadhesin family that functions as an inhibitory receptor in human natural killer cells J Exp Med 190 1999 793-802
49. T. Ulyanova D.D. Shah M.L. Thomas Molecular cloning of MIS, a myeloid inhibitory siglec, that binds protein-tyrosine phosphatases SHP-1 and SHP-2 J Biol Chem 276 2001 14451-14458
50. T. Avril S.D. Freeman H. Attrill R.G. Clarke P.R. Crocker Siglec-5 (CD170) can mediate inhibitory signaling in the absence of immunoreceptor tyrosine-based inhibitory motif phosphorylation J Biol Chem 280 2005 19843-19851
51. von Gunten S, Yousefi S, Seitz M, Jakob SM, Schaffner T, Seger R, Takala J, Villiger PM, Simon HU: Siglec-9 transduces apoptotic and non-apoptotic death signals into neutrophils depending on the pro-inflammatory cytokine environment. Blood 2005 [Epub ahead of print].