BMP4 inhibits the proliferation of breast cancer cells and induces an MMP-dependent migratory phenotype in MDA-MB-231 cells in 3D environment

BMC Cancer

Volumn 13, Issue , 2013, Pages

  Ampuja, Minna ^a,b   Jokimäki, Riikka ^a,b   Juuti Uusitalo, Kati ^a   Rodriguez Martinez, Alejandra ^a,b   Alarmo, Emma Leena ^a,b   Kallioniemi, Anne ^a,b  

^a TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^b FIMLAB LABORATORIES   (Finland)

Author keywords

3D culture; BMP4; Breast cancer; Matrigel; Migration; Proliferation

Indexed keywords

ALPHA6 INTEGRIN; BATIMASTAT; BONE MORPHOGENETIC PROTEIN 4; MACROGOL; MATRIGEL; MATRIX METALLOPROTEINASE; MATRIX METALLOPROTEINASE 14; PROTEIN P21; STROMELYSIN;

ANIMAL CELL; ARTICLE; BIOASSAY; BREAST CANCER; CANCER CELL; CANCER CELL CULTURE; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE REGULATION; CELL IMMORTALIZATION; CELL MIGRATION; CELL MOTILITY; CELL POLARITY; CELL PROLIFERATION; CELL STRAIN MDA MB 231; CELL STRAIN MDA MB 361; CELL STRUCTURE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CULTURE MEDIUM; IMMUNOFLUORESCENCE; MOLECULAR MECHANICS; MOUSE; NONHUMAN; PHENOTYPE; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STELLATE CELL; TUMOR GROWTH; WESTERN BLOTTING;

BONE MORPHOGENETIC PROTEIN 4; BREAST NEOPLASMS; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CYCLIN-DEPENDENT KINASE INHIBITOR P21; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; METALLOENDOPEPTIDASES; PHENOTYPE; SPHEROIDS, CELLULAR; TUMOR CELLS, CULTURED;

EID: 84884336670     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-13-429     Document Type: Article

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