-
1
-
-
0030925222
-
a novel human protein phosphatase that is induced in response to ionizing radiation in a p53-dependent manner
-
Fiscella M., Zhang H., Fan S., Sakaguchi K., Shen S., Mercer W.E., Vande Woude G.F., O'Connor P.M., and AppellaWip1 E. a novel human protein phosphatase that is induced in response to ionizing radiation in a p53-dependent manner. Proc Natl Acad Sci U S A 94 (1997) 6048-6053
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 6048-6053
-
-
Fiscella, M.1
Zhang, H.2
Fan, S.3
Sakaguchi, K.4
Shen, S.5
Mercer, W.E.6
Vande Woude, G.F.7
O'Connor, P.M.8
AppellaWip1, E.9
-
2
-
-
0342749295
-
The structure and expression of the murine wildtype p53-induced phosphatase 1 (Wip1) gene
-
Choi J., Appella E., and Donehower L.A. The structure and expression of the murine wildtype p53-induced phosphatase 1 (Wip1) gene. Genomics 64 (2000) 298-306
-
(2000)
Genomics
, vol.64
, pp. 298-306
-
-
Choi, J.1
Appella, E.2
Donehower, L.A.3
-
3
-
-
0034383398
-
p53-inducible wip1 phosphatase mediates a negative feedback regulation of p38 MAPK-p53 signaling in response to UV radiation
-
Takekawa M., Adachi M., Nakahata A., Nakayama I., Itoh F., Tsukuda H., Taya Y., and Imai K. p53-inducible wip1 phosphatase mediates a negative feedback regulation of p38 MAPK-p53 signaling in response to UV radiation. EMBO J 19 (2000) 6517-6526
-
(2000)
EMBO J
, vol.19
, pp. 6517-6526
-
-
Takekawa, M.1
Adachi, M.2
Nakahata, A.3
Nakayama, I.4
Itoh, F.5
Tsukuda, H.6
Taya, Y.7
Imai, K.8
-
4
-
-
1842483852
-
arf pathway
-
arf pathway. Nat Genet 36 (2004) 343-350
-
(2004)
Nat Genet
, vol.36
, pp. 343-350
-
-
Bulavin, D.V.1
Phillips, C.2
Nannenga, B.3
Timofeev, O.4
Donehower, L.A.5
Anderson, C.W.6
Appella, E.7
Fornace Jr., A.J.8
-
5
-
-
4344560876
-
The p53-induced oncogenic phosphatase PPM1D interacts with uracil DNA glycosylase and suppresses base excision repair
-
Lu X., Bocangel D., Nannenga B., Yamaguchi H., Appella E., and Donehower L.A. The p53-induced oncogenic phosphatase PPM1D interacts with uracil DNA glycosylase and suppresses base excision repair. Mol Cell 15 (2004) 621-634
-
(2004)
Mol Cell
, vol.15
, pp. 621-634
-
-
Lu, X.1
Bocangel, D.2
Nannenga, B.3
Yamaguchi, H.4
Appella, E.5
Donehower, L.A.6
-
6
-
-
18844405191
-
PPM1D dephosphorylates Chk1 and p53 and abrogates cell cycle checkpoints
-
Lu X., Nannenga B., and Donehower L.A. PPM1D dephosphorylates Chk1 and p53 and abrogates cell cycle checkpoints. Genes Dev 19 (2005) 1162-1174
-
(2005)
Genes Dev
, vol.19
, pp. 1162-1174
-
-
Lu, X.1
Nannenga, B.2
Donehower, L.A.3
-
7
-
-
33748150967
-
Wip1 phosphatase modulates ATM-dependent signaling pathways
-
Shreeram S., Demidov O.N., Hee W.K., Yamaguchi H., Onishi N., Kek C., Timofeev O.N., Dudgeon C., Fornace A.J., Anderson C.W., Minami Y., Appella E., and Bulavin D.V. Wip1 phosphatase modulates ATM-dependent signaling pathways. Mol Cell 23 (2006) 757-764
-
(2006)
Mol Cell
, vol.23
, pp. 757-764
-
-
Shreeram, S.1
Demidov, O.N.2
Hee, W.K.3
Yamaguchi, H.4
Onishi, N.5
Kek, C.6
Timofeev, O.N.7
Dudgeon, C.8
Fornace, A.J.9
Anderson, C.W.10
Minami, Y.11
Appella, E.12
Bulavin, D.V.13
-
8
-
-
33845893896
-
Regulation of ATM/p53-dependent suppression of myc-induced lymphomas by Wip1 phosphatase
-
Shreeram S., Hee W.K., Demidov O.N., Kek C., Yamaguchi H., Fornace Jr. A.J., Anderson C.W., Appella E., and Bulavin D.V. Regulation of ATM/p53-dependent suppression of myc-induced lymphomas by Wip1 phosphatase. J Exp Med 203 (2006) 2793-2799
-
(2006)
J Exp Med
, vol.203
, pp. 2793-2799
-
-
Shreeram, S.1
Hee, W.K.2
Demidov, O.N.3
Kek, C.4
Yamaguchi, H.5
Fornace Jr., A.J.6
Anderson, C.W.7
Appella, E.8
Bulavin, D.V.9
-
9
-
-
33745206498
-
Regulation of the antioncogenic Chk2 kinase by the oncogenic Wip1 phosphatase
-
Fujimoto H., Onishi N., Kato N., Takekawa M., Xu X.Z., Kosugi A., Kondo T., Imamura M., Oishi I., Yoda A., and Minami Y. Regulation of the antioncogenic Chk2 kinase by the oncogenic Wip1 phosphatase. Cell Death Differ 13 (2006) 1170-1180
-
(2006)
Cell Death Differ
, vol.13
, pp. 1170-1180
-
-
Fujimoto, H.1
Onishi, N.2
Kato, N.3
Takekawa, M.4
Xu, X.Z.5
Kosugi, A.6
Kondo, T.7
Imamura, M.8
Oishi, I.9
Yoda, A.10
Minami, Y.11
-
10
-
-
33847382384
-
The Wip1 phosphatase (PPM1D) antagonizes activation of the Chk2 tumour suppressor kinase
-
Oliva-Trastoy M., Berthonaud V., Chevalier A., Ducrot C., Marsolier-Kergoat M.C., Mann C., and Leteurtre F. The Wip1 phosphatase (PPM1D) antagonizes activation of the Chk2 tumour suppressor kinase. Oncogene 26 (2006) 1449-1458
-
(2006)
Oncogene
, vol.26
, pp. 1449-1458
-
-
Oliva-Trastoy, M.1
Berthonaud, V.2
Chevalier, A.3
Ducrot, C.4
Marsolier-Kergoat, M.C.5
Mann, C.6
Leteurtre, F.7
-
11
-
-
0036613212
-
Amplification of PPM1D in human tumors abrogates p53 tumor-suppressor activity
-
Bulavin D.V., Demidov O.N., Saito S., Kauraniemi P., Phillips C., Amundson S.A., Ambrosino C., Sauter G., Nebreda A.R., Anderson C.W., Kallioniemi A., Fornace Jr. A.J., and Appella E. Amplification of PPM1D in human tumors abrogates p53 tumor-suppressor activity. Nat Genet 31 (2002) 210-215
-
(2002)
Nat Genet
, vol.31
, pp. 210-215
-
-
Bulavin, D.V.1
Demidov, O.N.2
Saito, S.3
Kauraniemi, P.4
Phillips, C.5
Amundson, S.A.6
Ambrosino, C.7
Sauter, G.8
Nebreda, A.R.9
Anderson, C.W.10
Kallioniemi, A.11
Fornace Jr., A.J.12
Appella, E.13
-
12
-
-
18544385947
-
Oncogenic properties of PPM1D located within a breast cancer amplification epicenter at 17q23
-
Li J., Yang Y., Peng Y., Austin R.J., van Eyndhoven W.G., Nguyen K.C., Gabriele T., McCurrach M.E., Marks J.R., Hoey T., Lowe S.W., and Powers S. Oncogenic properties of PPM1D located within a breast cancer amplification epicenter at 17q23. Nat Genet 31 (2002) 133-134
-
(2002)
Nat Genet
, vol.31
, pp. 133-134
-
-
Li, J.1
Yang, Y.2
Peng, Y.3
Austin, R.J.4
van Eyndhoven, W.G.5
Nguyen, K.C.6
Gabriele, T.7
McCurrach, M.E.8
Marks, J.R.9
Hoey, T.10
Lowe, S.W.11
Powers, S.12
-
13
-
-
0037446975
-
PPM1D is a potential target for 17q gain in neuroblastoma
-
Saito-Ohara F., Imoto I., Inoue J., Hosoi H., Nakagawara A., Sugimoto T., and Inazawa J. PPM1D is a potential target for 17q gain in neuroblastoma. Cancer Res 63 (2003) 1876-1883
-
(2003)
Cancer Res
, vol.63
, pp. 1876-1883
-
-
Saito-Ohara, F.1
Imoto, I.2
Inoue, J.3
Hosoi, H.4
Nakagawara, A.5
Sugimoto, T.6
Inazawa, J.7
-
14
-
-
0037838822
-
Association of 17q21-q24 gain in ovarian clear cell adenocarcinomas with poor prognosis and identification of PPM1D and APPBP2 as likely amplification targets
-
Hirasawa A., Saito-Ohara F., Inoue J., Aoki D., Susumu N., Yokoyama T., Nozawa S., Inazawa J., and Imoto I. Association of 17q21-q24 gain in ovarian clear cell adenocarcinomas with poor prognosis and identification of PPM1D and APPBP2 as likely amplification targets. Clin Cancer Res 9 (2003) 1995-2004
-
(2003)
Clin Cancer Res
, vol.9
, pp. 1995-2004
-
-
Hirasawa, A.1
Saito-Ohara, F.2
Inoue, J.3
Aoki, D.4
Susumu, N.5
Yokoyama, T.6
Nozawa, S.7
Inazawa, J.8
Imoto, I.9
-
15
-
-
31544450175
-
Genomic and protein expression profiling identifies CDK6 as novel independent prognostic marker in medulloblastoma
-
Mendrzyk F., Radlwimmer B., Joos S., Kokocinski F., Benner A., Stange D.E., Neben K., Fiegler H., Carter N.P., Reifenberger G., Korshunov A., and Lichter P. Genomic and protein expression profiling identifies CDK6 as novel independent prognostic marker in medulloblastoma. J Clin Oncol 23 (2005) 8853-8862
-
(2005)
J Clin Oncol
, vol.23
, pp. 8853-8862
-
-
Mendrzyk, F.1
Radlwimmer, B.2
Joos, S.3
Kokocinski, F.4
Benner, A.5
Stange, D.E.6
Neben, K.7
Fiegler, H.8
Carter, N.P.9
Reifenberger, G.10
Korshunov, A.11
Lichter, P.12
-
16
-
-
33645216608
-
The serine-threonine protein phosphatase PPM1D is frequently activated through amplification in aggressive primary breast tumours
-
Rauta J., Alarmo E.L., Kauraniemi P., Karhu R., Kuukasjarvi T., and Kallioniemi A. The serine-threonine protein phosphatase PPM1D is frequently activated through amplification in aggressive primary breast tumours. Breast Cancer Res Treat 95 (2006) 257-263
-
(2006)
Breast Cancer Res Treat
, vol.95
, pp. 257-263
-
-
Rauta, J.1
Alarmo, E.L.2
Kauraniemi, P.3
Karhu, R.4
Kuukasjarvi, T.5
Kallioniemi, A.6
-
17
-
-
34247099845
-
The role of the MKK6/p38 MAPK pathway in Wip1-dependent regulation of ErbB2-driven mammary gland tumorigenesis
-
Demidov O.N., Kek C., Shreeram S., Timofeev O., Fornace A.J., Appella E., and Bulavin D.V. The role of the MKK6/p38 MAPK pathway in Wip1-dependent regulation of ErbB2-driven mammary gland tumorigenesis. Oncogene 26 (2007) 2502-2506
-
(2007)
Oncogene
, vol.26
, pp. 2502-2506
-
-
Demidov, O.N.1
Kek, C.2
Shreeram, S.3
Timofeev, O.4
Fornace, A.J.5
Appella, E.6
Bulavin, D.V.7
-
18
-
-
4043117002
-
Powers Scott. Wip1-deficient mice are resistant to common cancer genes
-
Harrison M., Li J., Degenhardt Y., and Hoye T. Powers Scott. Wip1-deficient mice are resistant to common cancer genes. Trends Mol Med 10 (2004) 359-361
-
(2004)
Trends Mol Med
, vol.10
, pp. 359-361
-
-
Harrison, M.1
Li, J.2
Degenhardt, Y.3
Hoye, T.4
-
19
-
-
0032441583
-
Molecular cytogenetic mapping of 24 CEPH YACs and 24 gene-specific large insert probes to chromosome 17
-
Bärlund M., Nupponen N.N., Karhu R., Tanner M.M., Paavola P., Kallioniemi O.P., and Kallioniemi A. Molecular cytogenetic mapping of 24 CEPH YACs and 24 gene-specific large insert probes to chromosome 17. Cytogenet Cell Genet 82 (1998) 189-191
-
(1998)
Cytogenet Cell Genet
, vol.82
, pp. 189-191
-
-
Bärlund, M.1
Nupponen, N.N.2
Karhu, R.3
Tanner, M.M.4
Paavola, P.5
Kallioniemi, O.P.6
Kallioniemi, A.7
-
20
-
-
0035942736
-
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
-
Elbashir S.M., Harborth J., Lendeckel W., Yalcin A., Weber K., and Tuschl T. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 411 (2001) 494-498
-
(2001)
Nature
, vol.411
, pp. 494-498
-
-
Elbashir, S.M.1
Harborth, J.2
Lendeckel, W.3
Yalcin, A.4
Weber, K.5
Tuschl, T.6
-
21
-
-
0036146455
-
Mice deficient for the wild-type p53-induced phosphatase gene (Wip1) exhibit defects in reproductive organs, immune function, and cell cycle control
-
Choi J., Nannenga B., Demidov O.N., Bulavin D.V., Cooney A., Brayton C., Zhang Y., Mbawuike I.N., Bradley A., Appella E., and Donehower L.A. Mice deficient for the wild-type p53-induced phosphatase gene (Wip1) exhibit defects in reproductive organs, immune function, and cell cycle control. Mol Cell Biol 22 (2002) 1094-1105
-
(2002)
Mol Cell Biol
, vol.22
, pp. 1094-1105
-
-
Choi, J.1
Nannenga, B.2
Demidov, O.N.3
Bulavin, D.V.4
Cooney, A.5
Brayton, C.6
Zhang, Y.7
Mbawuike, I.N.8
Bradley, A.9
Appella, E.10
Donehower, L.A.11
-
22
-
-
33645763906
-
Wip1 phosphatase-deficient mice exhibit defective T cell maturation due to sustained p53 activation
-
Schito M.L., Demidov O.N., Saito S., Ashwell J.D., and Appella E. Wip1 phosphatase-deficient mice exhibit defective T cell maturation due to sustained p53 activation. J Immunol 176 (2006) 4818-4825
-
(2006)
J Immunol
, vol.176
, pp. 4818-4825
-
-
Schito, M.L.1
Demidov, O.N.2
Saito, S.3
Ashwell, J.D.4
Appella, E.5
-
23
-
-
0025719004
-
Mutations in p53 as potential molecular markers for human breast cancer
-
Runnebaum I.B., Nagarajan M., Bowman M., Soto D., and Sukumar S. Mutations in p53 as potential molecular markers for human breast cancer. Proc Natl Acad Sci U S A 88 (1991) 10657-10661
-
(1991)
Proc Natl Acad Sci U S A
, vol.88
, pp. 10657-10661
-
-
Runnebaum, I.B.1
Nagarajan, M.2
Bowman, M.3
Soto, D.4
Sukumar, S.5
-
24
-
-
33845992547
-
E2F1 modulates p38 MAPK phosphorylation via transcriptional regulation of ASK1 and Wip1
-
Hershko T., Korotayev K., Polager S., and Ginsberg D. E2F1 modulates p38 MAPK phosphorylation via transcriptional regulation of ASK1 and Wip1. J Biol Chem 281 (2006) 31309-31316
-
(2006)
J Biol Chem
, vol.281
, pp. 31309-31316
-
-
Hershko, T.1
Korotayev, K.2
Polager, S.3
Ginsberg, D.4
-
25
-
-
27744481299
-
Chemical inhibition of Wip1 phosphatase contributes to suppression of tumorigenesis
-
Belova G.I., Demidov O.N., Fornace Jr. A.J., and Bulavin D.V. Chemical inhibition of Wip1 phosphatase contributes to suppression of tumorigenesis. Cancer Biol Ther 4 (2005) 1154-1158
-
(2005)
Cancer Biol Ther
, vol.4
, pp. 1154-1158
-
-
Belova, G.I.1
Demidov, O.N.2
Fornace Jr., A.J.3
Bulavin, D.V.4
|