Decreased mitochondrial DNA copy number in the hippocampus and peripheral blood during opiate addiction is mediated by autophagy and can be salvaged by melatonin

Autophagy

Volumn 9, Issue 9, 2013, Pages 1395-1406

  Feng, Yue Mei ^a,b   Jia, Yun Fang ^a,b   Su, Ling Yan ^a,b   Wang, Dong ^a,b   Lv, Li ^a,b   Xu, Lin ^a   Yao, Yong Gang ^a  

^a KUNMING INSTITUTE OF ZOOLOGY   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

Addiction; Autophagy; Melatonin; Mitochondrial dysfunction; Morphine

Indexed keywords

AUTOPHAGY PROTEIN 7; BAFILOMYCIN A1; DIAMORPHINE; MELATONIN; MEMBRANE PROTEIN; MITOCHONDRIAL DNA; MORPHINE; OPIATE; UNCLASSIFIED DRUG;

ADULT; ANALGESIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOPHAGY; BLOOD; CLINICAL ARTICLE; CONTROLLED STUDY; DNA DAMAGE; DRUG EFFICACY; DRUG MECHANISM; FEMALE; GENE DOSAGE; HEROIN DEPENDENCE; HIPPOCAMPUS; HUMAN; MALE; MEDIATOR; MORPHINE ADDICTION; MOUSE; NERVE CELL; NERVE FIBER GROWTH; NONHUMAN; OPIATE ADDICTION; OXIDATIVE STRESS; PHEOCHROMOCYTOMA CELL; PROTEIN BLOOD LEVEL; RAT; REDUCTION; SENSITIZATION; STRESS; WITHDRAWAL SYNDROME;

ANIMALIA; MUS; RATTUS;

ADDICTION; AUTOPHAGY; MELATONIN; MITOCHONDRIAL DYSFUNCTION; MORPHINE;

ANALGESICS; ANIMALS; AUTOPHAGY; BEHAVIOR, ANIMAL; CELLS, CULTURED; DENDRITES; DNA, MITOCHONDRIAL; GENE DOSAGE; HEROIN; HIPPOCAMPUS; HUMANS; MALE; MELATONIN; MICE; MITOCHONDRIA; MODELS, BIOLOGICAL; MORPHINE; NEURONS; OPIOID-RELATED DISORDERS; RATS; RATS, SPRAGUE-DAWLEY; SUBSTANCE WITHDRAWAL SYNDROME;

EID: 84884305932     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.4161/auto.25468     Document Type: Article

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