Melatonin modulates the GABAergic response in cultured rat hippocampal neurons

Journal of Pharmacological Sciences

Volumn 119, Issue 2, 2012, Pages 177-185

  Cheng, Xin Ping ^a   Sun, Hao ^a   Ye, Zeng You ^a   Zhou, Jiang Ning ^a  

^a UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

Author keywords

GABAergic miniature inhibitory postsynaptic current (mIPSC); Hippocampal neuron; Melatonin; Whole cell patch clamp technique

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; BACLOFEN; BENZODIAZEPINE DERIVATIVE; FLUMAZENIL; LUZINDOLE; MELATONIN; MELATONIN RECEPTOR; MEMBRANE RECEPTOR;

ALLOSTERISM; ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING SITE; CELL CULTURE; CONTROLLED STUDY; DOSE RESPONSE; GABAERGIC SYSTEM; GABAERGIC TRANSMISSION; HIPPOCAMPUS; ION SELECTIVE ELECTRODE; MINIATURE ENDPLATE POTENTIAL; NERVE CELL; NEUROPROTECTION; NONHUMAN; PATCH CLAMP; RAT;

EID: 84863107854     PISSN: 13478613     EISSN: 13478648     Source Type: Journal    
DOI: 10.1254/jphs.11183FP     Document Type: Article

References (44)

1. Harms C, Lautenschlager M, Bergk A, Freyer D, Weih M, Dirnagl U, et al. Melatonin is protective in necrotic but not in caspase-dependent, free radical-independent apoptotic neuronal cell death in primary neuronal cultures. FASEB J. 2000;14: 1814-1824.
2. Pappolla MA, Chyan YJ, Poeggeler B, Frangione B, Wilson G, Ghiso J, et al. An assessment of the antioxidant and the antiamyloidogenic properties of melatonin: implications for Alzheimer's disease. J Neural Transm. 2000;107:203-231. (Pubitemid 30095371)
3. Kwon KJ, Kim HJ, Shin CY, Han SH. Melatonin potentiates the neuroprotective properties of resveratrol against beta-amyloid-induced neurodegeneration by modulating AMP-activated protein kinase pathways. J Clin Neurol. 2010;6:127-137.
4. Chen LJ, Gao YQ, Li XJ, Shen DH, Sun FY. Melatonin protects against MPTP/MPP+ -induced mitochondrial DNA oxidative damage in vivo and in vitro. J Pineal Res. 2005;39:34-42.
5. Garcia T, Esparza JL, Nogues MR, Romeu M, Domingo JL, Gomez M. Oxidative stress status and RNA expression in hippocampus of an animal model of Alzheimer's disease after chronic exposure to aluminum. Hippocampus. 2010;20:218-225.
6. Lin HW, Lee EJ. Effects of melatonin in experimental stroke models in acute, sub-acute, and chronic stages. Neuropsychiatr Dis Treat. 2009;5:157-162.
7. Reiter RJ, Paredes SD, Korkmaz A, Manchester LC, Tan DX. Melatonin in relation to the "strong" and "weak" versions of the free radical theory of aging. Adv Med Sci. 2008;53:119-129.
8. Noguchi H, Kitazumi K, Mori M, Shiobara Y, Shiba T. Effect of zaleplon, a non-benzodiazepine hypnotic, on melatonin secretion in rabbits. J Pharmacol Sci. 2003;93:204-209. (Pubitemid 37390883)
9. Liu RY, Zhou JN, van Heerikhuize J, Hofman MA, Swaab DF. Decreased melatonin levels in postmortem cerebrospinal fluid in relation to aging, Alzheimer's disease, and apolipoprotein Eepsilon4/4 genotype. J Clin Endocrinol Metab. 1999;84: 323-327. (Pubitemid 29036721)
10. Zhou JN, Liu RY, Kamphorst W, Hofman MA, Swaab DF. Early neuropathological Alzheimer's changes in aged individuals are accompanied by decreased cerebrospinal fluid melatonin levels. J Pineal Res. 2003;35:125-130. (Pubitemid 36960352)
11. Costa E. From GABAA receptor diversity emerges a unified vision of GABAergic inhibition. Annu Rev Pharmacol Toxicol. 1998;38:321-350. (Pubitemid 28231498)
12. Macdonald RL, Olsen RW. GABAA receptor channels. Annu Rev Neurosci. 1994;17:569-602. (Pubitemid 2067782)
13. Watanabe M, Maemura K, Kanbara K, Tamayama T, Hayasaki H. GABA and GABA receptors in the central nervous system and other organs. Int Rev Cytol. 2002;213:1-47. (Pubitemid 34121040)
14. Kanematsu T, Mizokami A, Watanabe K, Hirata M. Regulation of GABA(A)-receptor surface expression with special reference to the involvement of GABARAP (GABA(A) receptor-associated protein) and PRIP (phospholipase C-related, but catalytically inactive protein). J Pharmacol Sci. 2007;104:285-292. (Pubitemid 47378415)
15. Esclapez M, Hirsch JC, Khazipov R, Ben-Ari Y, Bernard C. Operative GABAergic inhibition in hippocampal CA1 pyramidal neurons in experimental epilepsy. Proc Natl Acad Sci U S A. 1997;94:12151-12156. (Pubitemid 27467858)
16. Lydiard RB. The role of GABA in anxiety disorders. J Clin Psychiatry. 2003;64 Suppl 3:21-27. (Pubitemid 36389868)
17. Tunnicliff G, Malatynska E. Central GABAergic systems and depressive illness. Neurochem Res. 2003;28:965-976. (Pubitemid 36438415)
18. Fritschy JM. Epilepsy, E/I balance and GABA(A) receptor plasticity. Front Mol Neurosci. 2008;1:5.
19. Jones-Davis DM, Macdonald RL. GABA(A) receptor function and pharmacology in epilepsy and status epilepticus. Curr Opin Pharmacol. 2003;3:12-18. (Pubitemid 36131321)
20. Wu FS, Yang YC, Tsai JJ. Melatonin potentiates the GABA(A) receptor-mediated current in cultured chick spinal cord neurons. Neurosci Lett. 1999;260:177-180.
21. Wan Q, Man HY, Liu F, Braunton J, Niznik HB, Pang SF, et al. Differential modulation of GABAA receptor function by Mel1a and Mel1b receptors. Nat Neurosci. 1999;2:401-403. (Pubitemid 30491246)
22. Shen Y, Specht SM, De Saint Ghislain I, Li R. The hippocampus: a biological model for studying learning and memory. Prog Neurobiol. 1994;44:485-496. (Pubitemid 24372700)
23. Kirino T. Delayed neuronal death in the gerbil hippocampus following ischemia. Brain Res. 1982;239:57-69. (Pubitemid 12101768)
24. Pulsinelli WA, Brierley JB, Plum F. Temporal profile of neuronal damage in a model of transient forebrain ischemia. Ann Neurol. 1982;11:491-498. (Pubitemid 12158810)
25. El-Sherif Y, Tesoriero J, Hogan MV, Wieraszko A. Melatonin regulates neuronal plasticity in the hippocampus. J Neurosci Res. 2003;72:454-460. (Pubitemid 36523420)
26. Hogan MV, El-Sherif Y, Wieraszko A. The modulation of neuronal activity by melatonin: in vitro studies on mouse hippocampal slices. J Pineal Res. 2001;30:87-96. (Pubitemid 32176211)
27. Zeise ML, Semm P. Melatonin lowers excitability of guinea pig hippocampal neurons in vitro. J Comp Physiol A. 1985;157: 23-29. (Pubitemid 15046519)
28. Murase K, Randic M, Shirasaki T, Nakagawa T, Akaike N. Serotonin suppresses N-methyl-D-aspartate responses in acutely isolated spinal dorsal horn neurons of the rat. Brain Res. 1990; 525:84-91. (Pubitemid 20257719)
29. Li GL, Li P, Yang XL. Melatonin modulates gamma-aminobutyric acid(A) receptor-mediated currents on isolated carp retinal neurons. Neurosci Lett. 2001;301:49-53. (Pubitemid 32182392)
30. Xu H, Gong N, Chen L, Xu TL. Sodium salicylate reduces gamma aminobutyric acid-induced current in rat spinal dorsal horn neurons. Neuroreport. 2005;16:813-816. (Pubitemid 40733791)
31. Dubocovich ML. Luzindole (N-0774): a novel melatonin receptor antagonist. J Pharmacol Exp Ther. 1988;246:902-910.
32. Iuvone PM, Gan J. Functional interaction of melatonin receptors and D1 dopamine receptors in cultured chick retinal neurons. J Neurosci. 1995;15:2179-2185.
33. Rabow LE, Russek SJ, Farb DH. From ion currents to genomic analysis: recent advances in GABAA receptor research. Synapse. 1995;21:189-274.
34. Weiss M, Tikhonov D, Buldakova S. Effect of flumazenil on GABAA receptors in isolated rat hippocampal neurons. Neurochem Res. 2002;27:1605-1612. (Pubitemid 36020113)
35. Hall BJ, Chebib M, Hanrahan JR, Johnston GA. Flumazenil-independent positive modulation of gamma-aminobutyric acid action by 6-methylflavone at human recombinant alpha1-beta2-gamma2L and alpha1beta2 GABAA receptors. Eur J Pharmacol. 2004;491:1-8.
36. Pang SF, Li Y, Jiang DH, Chang B, Xie BL. Acute cerebral hemorrhage changes the nocturnal surge of plasma melatonin in humans. J Pineal Res. 1990;9:193-208.
37. Giusti P, Gusella M, Lipartiti M, Milani D, Zhu W, Vicini S, et al. Melatonin protects primary cultures of cerebellar granule neurons from kainate but not from N-methyl-D-aspartate excitotoxicity. Exp Neurol. 1995;131:39-46.
38. de Lima E, Soares JM Jr, del Carmen Sanabria Garrido Y, Gomes Valente S, Priel MR, Chada Baracat E, et al. Effects of pinealectomy and the treatment with melatonin on the temporal lobe epilepsy in rats. Brain Res. 2005;1043:24-31. (Pubitemid 40613043)
39. Lapin IP, Mirzaev SM, Ryzov IV, Oxenkrug GF. Anticonvulsant activity of melatonin against seizures induced by quinolinate, kainate, glutamate, NMDA, and pentylenetetrazole in mice. J Pineal Res. 1998;24:215-218. (Pubitemid 28206441)
40. Molina-Carballo A, Munoz-Hoyos A, Reiter RJ, Sanchez-Forte M, Moreno-Madrid F, Rufo-Campos M, et al. Utility of high doses of melatonin as adjunctive anticonvulsant therapy in a child with severe myoclonic epilepsy: two years' experience. J Pineal Res. 1997;23:97-105. (Pubitemid 127731744)
41. Yildirim M, Marangoz C. Anticonvulsant effects of melatonin on penicillin-induced epileptiform activity in rats. Brain Res. 2006; 1099:183-188. (Pubitemid 44080090)
42. Solmaz I, Gurkanlar D, Gokcil Z, Goksoy C, Ozkan M, Erdogan E. Antiepileptic activity of melatonin in guinea pigs with pentylenetetrazol- induced seizures. Neurol Res. 2009;31:989-995.
43. Banach M, Gurdziel E, Jedrych M, Borowicz KK. Melatonin in experimental seizures and epilepsy. Pharmacol Rep. 2011;63: 1-11.
44. Fujiwara-Tsukamoto Y, Isomura Y, Nambu A, Takada M. Excitatory GABA input directly drives seizure-like rhythmic synchronization in mature hippocampal CA1 pyramidal cells. Neuroscience. 2003;119:265-275. (Pubitemid 36577429)