Chronic administration of heroin to mice produces up-regulation of brain apoptosis-related proteins and impairs spatial learning and memory

Neuropharmacology

Volumn 54, Issue 4, 2008, Pages 640-652

  Tramullas, Mónica ^a   Martínez Cué, Carmen ^a   Hurlé, María A ^a  

^a UNIVERSITY OF CANTABRIA   (Spain)

Author keywords

Apoptosis; Dependence; Heroin; Learning; Memory; Opioid; Tolerance

Indexed keywords

DIAMORPHINE; FAS LIGAND; PROTEIN BAD; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL;

ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; BRAIN; COGNITION; CONTROLLED STUDY; HIPPOCAMPUS; LEARNING; MALE; MAZE TEST; MEMORY; MOUSE; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENSORIMOTOR FUNCTION; TASK PERFORMANCE; UPREGULATION; WESTERN BLOTTING;

ANALYSIS OF VARIANCE; ANIMALS; APOPTOSIS REGULATORY PROTEINS; BCL-ASSOCIATED DEATH PROTEIN; BEHAVIOR, ANIMAL; BRAIN; FAS LIGAND PROTEIN; HEROIN; IN SITU NICK-END LABELING; LOCOMOTION; MALE; MAZE LEARNING; MEMORY; MICE; MICE, INBRED C57BL; MOTOR ACTIVITY; NARCOTICS; PSYCHOMOTOR PERFORMANCE; TIME FACTORS; UP-REGULATION;

EID: 38749122062     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2007.11.018     Document Type: Article

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