Stabilization of bovine insulin against agitation-induced aggregation using RNA aptamers

International Journal of Pharmaceutics

Volumn 452, Issue 1-2, 2013, Pages 257-265

  Malik, Ravinder ^a   Roy, Ipsita ^a  

^a NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER   (India)

Author keywords

Aptamer; Diabetes; Fibrillation; Insulin; Protein stabilization

Indexed keywords

APTAMER; BOVINE INSULIN; GLUCOSE; RNA; STREPTOZOCIN; THIOFLAVINE;

AGAR GEL ELECTROPHORESIS; AGITATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIDIABETIC ACTIVITY; AREA UNDER THE CURVE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DIABETES CONTROL; DISSOCIATION CONSTANT; DRUG BIOAVAILABILITY; DRUG STABILITY; GLUCOSE BLOOD LEVEL; IMMUNOBLOTTING; IN VITRO SELECTION; INSULIN BINDING; MALE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; RAT; RNA SEQUENCE; SEQUENCE ANALYSIS; SINGLE DRUG DOSE; SKELETAL MUSCLE; STREPTOZOCIN DIABETES; TURBIDITY;

EID: 84884209192     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2013.05.004     Document Type: Article

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