Protein-protein interactions: Hot spots and structurally conserved residues often locate in complemented pockets that pre-organized in the unbound states: Implications for docking

Journal of Molecular Biology

Volumn 344, Issue 3, 2004, Pages 781-795

  Li, Xiang ^a   Keskin, Ozlem ^b,c   Ma, Buyong ^c   Nussinov, Ruth ^c,d   Liang, Jie ^a  

^a University of Illinois at Chicago   (United States)

^b KOÇ UNIVERSITY   (Turkey)

^c SAIC FREDERICK INC   (United States)

^d TEL AVIV UNIVERSITY   (Israel)

Author keywords

binding and folding; protein docking; protein protein interactions; residue conservation; residue hot spots

Indexed keywords

ALANINE; DOCKING PROTEIN;

ARTICLE; BAY REGION BINDING SITE; ENERGY TRANSFER; HYDROGEN BOND; MOLECULAR WEIGHT; PARTICLE SIZE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FOLDING; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; STRUCTURE ANALYSIS;

EID: 7944225979     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2004.09.051     Document Type: Article

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