The importance of anti-insulin antibody in patients with type 1 diabetes mellitus treated with continuous subcutaneous insulin infusion or multiple daily insulin injections therapy

Acta Diabetologica

Volumn 47, Issue 4, 2010, Pages 325-330

  Sahin, S B ^a   Cetinkalp, S ^a   Ozgen, A G ^a   Saygili, F ^a   Yilmaz, C ^a  

^a EGE UNIVERSITY SCHOOL OF MEDICINE   (Turkey)

Author keywords

Anti insulin antibody; Continuous subcutaneous insulin infusion; Multiple daily insulin injections; Type 1 diabetes

Indexed keywords

GLUCOSE; HEMOGLOBIN A1C; INSULIN ANTIBODY; INSULIN ASPART; INSULIN DERIVATIVE; INSULIN DETEMIR; INSULIN GLARGINE; INSULIN GLULISINE; INSULIN LISPRO;

ADULT; AGE; AGED; ANTIBODY DETECTION; ANTIBODY PRODUCTION; ARTICLE; CONTINUOUS INFUSION; CONTROLLED STUDY; DISEASE DURATION; DOSAGE SCHEDULE COMPARISON; FEMALE; GLUCOSE BLOOD LEVEL; GLYCEMIC CONTROL; HEMOGLOBIN BLOOD LEVEL; HUMAN; HYPOGLYCEMIA; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN TREATMENT; MAJOR CLINICAL STUDY; MALE; OBSERVATIONAL STUDY; POSTPRANDIAL STATE; PRIORITY JOURNAL;

ADULT; BLOOD GLUCOSE; CIRCADIAN RHYTHM; CROSS-SECTIONAL STUDIES; DIABETES MELLITUS, TYPE 1; DRUG ADMINISTRATION SCHEDULE; FEMALE; HUMANS; HYPOGLYCEMIA; HYPOGLYCEMIC AGENTS; INFUSIONS, SUBCUTANEOUS; INJECTIONS, INTRAMUSCULAR; INSULIN; INSULIN INFUSION SYSTEMS; MALE; MIDDLE AGED; YOUNG ADULT;

EID: 78549275048     PISSN: 09405429     EISSN: 14325233     Source Type: Journal    
DOI: 10.1007/s00592-010-0221-5     Document Type: Article

References (47)

1. TW Van Haeften 1989 Clinical significance of insulin antibodies in insulin-treated diabetic patients Diabetes Care 12 9 641 648 10.2337/diacare.12.9.641 2676431 Review
2. AB Kurtz JD Nabarro 1980 Circulating insulin-binding antibodies Diabetologia 19 4 329 334 1:STN:280:DyaL3M%2FksVOntg%3D%3D 10.1007/BF00280515 7000597 Review (Pubitemid 10003998)
3. S Oak TH Phan LK Gilliam IB Hirsch CS Hampe 2010 Animal insulin therapy induces a biased insulin antibody response that persists for years after introduction of human insulin Acta Diabetol 47 2 131 135 1:CAS:528: DC%2BC3cXlt1ags7Y%3D 10.1007/s00592-009-0135-2 19547910
4. J Brange DR Owens S Kang A Vølund 1990 Monomeric insulins and their experimental and clinical implications Diabetes Care 13 9 923 954 1:STN:280:DyaK3M%2FjtV2jtQ%3D%3D 10.2337/diacare.13.9.923 2226110
5. JL Ottesen P Nilsson J Jami D Weilguny M Dührkop D Bucchini, et al. 1994 The potential immunogenicity of human insulin and insulin analogues evaluated in a transgenic mouse model Diabetologia 37 12 1178 1185 1:CAS:528:DyaK2MXjvVKnt7o%3D 10.1007/BF00399790 7895946
6. C Jaeger S Winter M Eckhard P Hardt MD Brendel RG Bretzel 2008 Binding characteristics and crossreactivity of insulin autoantibodies and insulin antibodies directed to three different insulin molecules Acta Diabetol 45 3 191 194 1:CAS:528:DC%2BD1cXpt1Smsrw%3D 10.1007/s00592-008-0041-z 18493700
7. K Jeitler K Horvath A Berghold TW Gratzer K Neeser TR Pieber, et al. 2008 Continuous subcutaneous insulin infusion versus multiple daily insulin injections in patients with diabetes mellitus: systematic review and meta-analysis Diabetologia 51 6 941 951 1:CAS:528:DC%2BD1cXlt1Crs7w%3D 10.1007/s00125-008-0974-3 18351320 Review
8. JC Pickup AJ Sutton 2008 Severe hypoglycaemia and glycaemic control in type 1 diabetes:meta-analysis of multiple daily insulin injections compared with continuous subcutaneous insulin infusion Diabet Med 25 7 765 774 1:CAS:528:DC%2BD1cXpvFyitbY%3D 10.1111/j.1464-5491.2008.02486.x 18644063 Review
9. K Dahl-Jørgensen P Torjesen KF Hanssen L Sandvik O Aagenaes 1987 Increase in insulin antibodies during continuous subcutaneous insulin infusion and multiple-injection therapy in contrast to conventional treatment Diabetes 36 1 1 5 10.2337/diabetes.36.1.1 3539672
10. Colquitt J, Royle P, Waugh N (2003) Are analogue insulins better than soluble in continuous subcutaneous insulin infusion? Results of a meta-analysis. Diabet Med (10):863-866 (Review)
11. RP Radermecker AJ Scheen 2004 Continuous subcutaneous insulin infusion with shortacting insulin analogues or human regular insulin: efficacy, safety, quality of life, and cost-effectiveness Diabetes Metab Res Rev 20 3 178 188 1:CAS:528:DC%2BD2cXltFOlur0%3D 10.1002/dmrr.447 15133748 Review (Pubitemid 38714315)
12. RS Moisés JR Sá AR Chacra EM Russo 1990 Relationship between insulin antibodies and metabolic control in type I diabetes mellitus Braz J Med Biol Res 23 12 1243 1252 2136556
13. A Livneh H Avraham T Bistritzer L Weisglass R Theodor J Sack 1990 Deleterious effect of anti-insulin antibodies on diabetes control Isr J Med Sci 26 1 11 15 1:STN:280:DyaK3c7os1Wnsw%3D%3D 2179155
14. M Fernández Castañer M Pérez J Maravall E Montaña J Soler 1996 Lack of relationship between insulin antibodies, metabolic control and insulin requirements in type 1 diabetes Diabet Med 13 7 686 687 10.1002/(SICI)1096-9136(199607)13:7<686::AID-DIA155>3.0.CO;2-P 8840111 (Pubitemid 26232515)
15. R Wredling PE Lins U Adamson 1990 Prevalence of anti-insulin antibodies and its relation to severe hypoglycaemia in insulin-treated diabetic patients Scand J Clin Lab Invest 50 5 551 557 1:STN:280:DyaK3M%2FkslOrtQ%3D%3D 10.3109/00365519009089170 2237267
16. N Dozio A Beretta M Castiglioni S Rosa M Scavini C Belloni, et al. 1996 Insulin antibodies do not preclude optimization of metabolic control in women with IDDM during pregnancy Diabetes Care 19 9 979 982 1:STN:280: DyaK2s%2FivFSrsg%3D%3D 10.2337/diacare.19.9.979 8875092
17. S Sakata M Matsuda T Komaki K Miura 1986 Effect of anti-insulin antibodies on glycemic control in insulin treated diabetic patients Immunol Invest 15 8 791 799 1:STN:280:DyaL2s3kvV2gug%3D%3D 10.3109/08820138609036363 3298026
18. G Antony SG Cooper LC Svejkar 1991 Continuous subcutaneous insulin infusion (CSII) and insulin antibodies in rabbits Diabetes Res Clin Pract 12 1 41 51 1:CAS:528:DyaK3MXlsFWitbc%3D 10.1016/0168-8227(91)90129-2 1855440
19. CE de Beaufort CM Houtzagers GJ Bruining RS Aarsen NC den Boer WF Grose, et al. 1989 Continuous subcutaneous insulin infusion (CSII) versus conventional injection therapy in newly diagnosed diabetic children: two-year follow-up of a randomized, prospective trial Diabet Med 6 9 766 771 10.1111/j.1464-5491.1989. tb01276.x 2533034
20. H Beck-Nielsen B Richelsen C Hasling OH Nielsen L Heding NS Sørensen 1984 Improved in vivo insulin effect during continuous subcutaneous insulin infusion in patients with IDDM Diabetes 33 9 832 837 1:STN:280:DyaL2c3os1Cjsg%3D%3D 10.2337/diabetes.33.9.832 6381179
21. H Beck-Nielsen B Richelsen N Schwartz Sørensen O Hother Nielsen 1985 Insulin pump treatment: effect on glucose homeostasis, metabolites, hormones, insulin antibodies and quality of life Diabetes Res 2 1 37 43 1:STN:280:DyaL2M3gt1Glsg%3D%3D 3888495
22. Henrivaux P, Daubresse JC, Scheen A, Luyckx A, Lefèbvre PJ (1985) Effect of long- term continuous subcutaneous insulin infusion (CSII) on serum anti- insulin antibodies: comparison between pocine and semisynthetic human insulin. Diabetes Res Clin Pract (Suppl 1): S234-S235
23. AJ Scheen P Henrivaux B Jandrain PJ Lefebvre 1986 Anti-insulin antibodies and metabolic deterioration after interruption of continuous subcutaneous insulin infusion Diabetes Care 9 6 673 674 1:STN:280:DyaL2s7gsV2rtQ%3D%3D 3803158
24. Fineberg SE, Kawabata TT, Finco-Kent D, Fountaine RJ, Finch GL, Krasner AS (2007) Immunological responses to exogenous insulin. Endocr Rev 28(6):625-652 (Epub 2007 Sep 4 Review)
25. AS Chawla I Hinberg P Blais D Johnson 1985 Aggregation of insulin, containing surfactants, in contact with different materials Diabetes 34 5 420 424 1:CAS:528:DyaL2MXkt1OitLo%3D 10.2337/diabetes.34.5.420 3886458
26. DC Robbins SM Cooper SE Fineberg PM Mead 1987 Antibodies to covalent aggregates of insulin in blood of insulin-using diabetic patients Diabetes 36 7 838 841 1:STN:280:DyaL2s3hvFGgtw%3D%3D 10.2337/diabetes.36.7.838 2438179
27. RA Miller 1996 The aging immune system: primer and prospectus Science 273 5271 70 74 1:CAS:528:DyaK28XjvFOks7c%3D 10.1126/science.273.5271.70 8658199 Review
28. SE Fineberg JA Galloway NS Fineberg J Goldman 1983 Effects of species of origin, purification levels, and formulation on insulin immunogenicity Diabetes 32 7 592 599 1:CAS:528:DyaL3sXls1erurs%3D 10.2337/diabetes.32.7.592 6345238
29. SE Fineberg T Kawabata D Finco-Kent C Liu A Krasner 2005 Antibody response to inhaled insulin in patients with type 1 or type 2 diabetes. An analysis of initial phase II and III inhaled insulin (Exubera) trials and a two-year extension trial J Clin Endocrinol Metab 90 6 3287 3294 1:CAS:528:DC%2BD2MXkvFClsbo%3D 10.1210/jc.2004-2229 15741258 (Pubitemid 41014288)
30. AJ Francis I Hanning KG Alberti 1985 The influence of insulin antibody levels on the plasma profiles and action of subcutaneously injected human and bovine short acting insulins Diabetologia 28 6 330 334 1:STN:280: DyaL28%2FgsF2rsg%3D%3D 10.1007/BF00283138 3899818
31. TW Van Haeften VJ Heiling JE Gerich 1987 Adverse effects of insulin antibodies on postprandial plasma glucose and insulin profiles in diabetic patients without immune insulin resistance. Implications for intensive insulin regimens Diabetes 36 3 305 309 10.2337/diabetes.36.3.305 3542653
32. T Bistritzer J Sack R Theodor L Weissglass I Ben-Bassat M Lahav 1984 Correlation between HbA1c, purified insulins, diabetic control, and insulin antibodies in diabetic children Horm Res 20 3 178 185 1:STN:280: DyaL2M%2FivVymsA%3D%3D 10.1159/000179993 6386647
33. R Goswami A Jaleel NP Kochupillai 2000 Insulin antibody response to bovine insulin therapy: functional significance among insulin requiring young diabetics in India Diabetes Res Clin Pract 49 1 7 15 1:CAS:528: DC%2BD3cXjtVequ7g%3D 10.1016/S0168-8227(00)00130-3 10808058 (Pubitemid 30243164)
34. B Gonen J Goldman D Baldwin RB Goldberg WG Ryan PM Blix, et al. 1979 Metabolic control in diabetic patients. Effect of insulin-secretory reserve (measured by plasma C-peptide levels) and circulating insulin antibodies Diabetes 28 8 749 753 1:CAS:528:DyaE1MXlt1Wltbo%3D 10.2337/diabetes.28.8.749 446933
35. A Hübinger A Becker FA Gries 1988 Total insulin levels in type 1 diabetic patients with insulin antibodies and their effect on insulin requirement and metabolic control Diabetes Res 7 2 65 69 3293878
36. UM Kabadi M Birkenholz 1992 Metabolic control following transfer from mixed bovine-porcine insulin to human insulin in subjects with IDDM: influence of the presence of insulin antibodies Diabetes Res 19 4 187 193 1:STN:280:DyaK2c7itlGhtQ%3D%3D 1343115
37. F Virgili F Frigato PG Magnanini GA Coronel M Iavicoli 1988 Reduction in insulin antibodies 42 months after transfer from porcine to human monocomponent insulins Diabetes Res 9 1 19 20 1:STN:280:DyaL1M7psFylsg%3D%3D 3071441
38. S Walford SP Allison WG Reeves 1982 The effect of insulin antibodies on insulin dose and diabetic control Diabetologia 22 2 106 110 1:STN:280: DyaL387jvFyntw%3D%3D 10.1007/BF00254838 7037511
39. CM Asplin M Hartog DJ Goldie KG Alberti P Smythe C Binder, et al. 1978 A comparison between diabetics receiving a high or low daily insulin dosage Horm Metab Res 10 5 365 369 1:STN:280:DyaE1M%2Fks1OksQ%3D%3D 10.1055/s-0028-1093392 568594
40. L Kerp H Kasemir 1976 High and low affinity insulin antibodies Acta Endocrinol Suppl (Copenh) 205 211 222 1:STN:280:DyaE2s%2Fmt1WltA%3D%3D
41. H Keilacker I Rjasanowski M Ziegler D Michaelis KP Woltanski W Besch 1982 Insulin antibodies in juvenile diabetes mellitus. Correlations to diabetic stability, insulin requirement and duration of insulin treatment Horm Metab Res 14 5 227 232 1:STN:280:DyaL383jslyjtA%3D%3D 10.1055/s-2007-1018979 7047344
42. MR Kim LR Sheeler N Mansharamani MT Haug C Faiman MK Gupta 1997 Insulin antibodies and hypoglycemia in diabetic patients. Can a quantitative analysis of antibody binding predict the risk of hypoglycemia? Endocrine 6 3 285 291 1:CAS:528:DyaK2sXmt1Sitr8%3D 10.1007/BF02820505 9368685
43. RP Radermecker E Renard AJ Scheen 2009 Circulating insulin antibodies: influence of continuous subcutaneous or intraperitoneal insulin infusion, and impact on glucose control Diabetes Metab Res Rev 25 6 491 501 1:CAS:528:DC%2BD1MXht1GntrzO 10.1002/dmrr.961 19496088
44. R Koyama K Nakanishi M Kato S Yamashita H Kuwahara H Katori 2005 Hypoglycemia and hyperglycemia due to insulin antibodies against therapeutic human insulin: treatment with double filtration plasmapheresis and prednisolone Am J Med Sci 329 5 259 264 10.1097/00000441-200505000-00007 15894868 (Pubitemid 40695453)
45. A Matsuyoshi S Shimoda K Tsuruzoe K Taketa T Chirioka F Sakamoto, et al. 2006 A case of slowly progressive type 1 diabetes with unstable glycemic control caused by unusual insulin antibody and successfully treated with steroid therapy Diabetes Res Clin Pract 72 3 238 243 1:CAS:528:DC%2BD28XltVeltro%3D 10.1016/j.diabres.2005.10.018 16439034 (Pubitemid 43729135)
46. K Suzuki S Hirayama S Ito 1997 A case of a non-insulin dependent diabetic patient with regular spontaneous hypoglycemic attacks, which were due to insulin-binding antibodies induced by human insulin therapy Tohoku J Exp Med 182 2 163 173 1:STN:280:DyaK2svgsFaltw%3D%3D 10.1620/tjem.182.163 9261935 (Pubitemid 27435252)
47. CM Asplin M Hartog DJ Goldie 1978 The relationship between circulating free and bound insulin, insulin antibodies, insulin dosage and diabetic control in insulin treated diabetics Acta Endocrinol (Copenh) 87 2 330 338 1:CAS:528:DyaE1cXotl2ntQ%3D%3D (Pubitemid 8264867)