Canadian boreal pulp and paper feedstocks contain neuroactive substances that interact in vitro with GABA and dopaminergic systems in the brain

Science of the Total Environment

Volumn 468-469, Issue , 2014, Pages 315-325

  Waye, Andrew ^a   Annal, Malar ^a   Tang, Andrew ^a   Picard, Gabriel ^a   Harnois, Frédéric ^a   Guerrero Analco, José A ^a   Saleem, Ammar ^a   Hewitt, L Mark ^b   Milestone, Craig B ^b   MacLatchy, Deborah L ^c   Trudeau, Vance L ^a   Arnason, John T ^a  

^a UNIVERSITY OF OTTAWA   (Canada)

^b ENVIRONMENT CANADA   (Canada)

^c WILFRID LAURIER UNIVERSITY   (Canada)

Author keywords

Dopamine; Gamma aminobutyric acid; Natural products; Neuroendocrine disruption; Phytochemistry; Pulp and paper conifer feedstocks

Indexed keywords

AMINO ACIDS; EFFLUENTS; FEEDSTOCKS; FORESTRY; NEUROLOGY; PAPER; WOOD CHEMICALS;

DOPAMINE; GAMMA-AMINOBUTYRIC ACIDS; NATURAL PRODUCTS; NEUROENDOCRINE DISRUPTION; PHYTOCHEMISTRY; PULP AND PAPER;

PULP;

3 HYDROXY 5 METHOXYSTILBENE; 4 AMINOBUTYRATE AMINOTRANSFERASE; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 ETHYLGUAIACOL; ABIETIC ACID; ALKENE DERIVATIVE; AMINE OXIDASE (FLAVIN CONTAINING); DEHYDROABIETIC ACID; GLUTAMATE DECARBOXYLASE; ISOEUGENOL; ISOPIMARIC ACID; LEVOPIMARIC ACID; MANOOL; NEOABIETIC ACID; PALUSTRIC ACID; PHENOL DERIVATIVE; PHENYLPROPENE DERIVATIVE; PIMARIC ACID; PINOSYLVIN; RESIN; SANDARACOPIMARIC ACID; STILBENE DERIVATIVE; TERPENOID; UNCLASSIFIED DRUG; VANILLIN; VERATRALDEHYDE;

BRAIN; CHEMICAL COMPOUND; CONIFEROUS TREE; EFFLUENT; ENDOCRINE DISRUPTOR; ENZYME ACTIVITY; PLANT EXTRACT; WOOD;

ANIMAL TISSUE; ANXIETY; ARTICLE; BALSAM FIR; BIODIVERSITY; BLACK SPRUCE; BRAIN TISSUE; CANADA; CONIFER; CONTROLLED STUDY; DEPRESSION; DOPAMINERGIC SYSTEM; DRUG BINDING SITE; EFFLUENT; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; EPILEPSY; FEMALE; GABAERGIC SYSTEM; GOLDFISH; IN VITRO STUDY; LIGAND BINDING; MALE; NEUROENDOCRINE SYSTEM; NEUROLOGIC DISEASE; NONHUMAN; PAPER FEEDSTOCK; PHYTOCHEMISTRY; PLANT PRODUCT; PRIORITY JOURNAL; RAT; RECEPTOR BINDING; REPRODUCTIVE TOXICITY; WHITE SPRUCE; WOOD PULP;

AMINO ACIDS; EFFLUENTS; FORESTRY; NEUROLOGY; PULPS;

ABIES BALSAMEA; CONIFEROPHYTA; PICEA GLAUCA; PICEA MARIANA;

DA; DOPAMINE; GABA; GABA(A) RECEPTOR BENZODIAZEPINE-BINDING SITE; GABA(A)-BZD; GABA-T; GABA-TRANSAMINASE; GAD; GAMMA-AMINOBUTYRIC ACID; GLUTAMIC ACID DECARBOXYLASE; GNRH; GONADOTROPIN-RELEASING HORMONE; LH; LUTEINIZING HORMONE; MAO; MONOAMINE OXIDASE; NATURAL PRODUCTS; NEUROENDOCRINE DISRUPTION; PHYTOCHEMISTRY; PULP AND PAPER CONIFER FEEDSTOCKS;

ANALYSIS OF VARIANCE; ANIMALS; BRAIN; CANADA; CONIFEROPHYTA; DOPAMINERGIC NEURONS; GAMMA-AMINOBUTYRIC ACID; GLUTAMATE DECARBOXYLASE; GOLDFISH; MONOAMINE OXIDASE; NEUROSECRETORY SYSTEMS; PAPER; PLANT EXTRACTS; RATS; SCINTILLATION COUNTING;

EID: 84884191617     PISSN: 00489697     EISSN: 18791026     Source Type: Journal    
DOI: 10.1016/j.scitotenv.2013.08.040     Document Type: Article

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