Bioactive properties of wood knot extracts on cultured human cells

Journal of Medicinal Food

Volumn 12, Issue 6, 2009, Pages 1245-1251

  Phelan, Martha ^a   Aherne, S Aisling ^a   Wong, Alfred ^b   O'Brien, Nora M ^a  

^a UNIVERSITY COLLEGE CORK   (Ireland)

^b Arbokem Inc   (Canada)

Author keywords

Antioxidant; Comet assay; Interleukin 2; Picea sitchensis; Pinus banksiana Lamb.

Indexed keywords

CATALASE; CONCANAVALIN A; GLUTATHIONE; HYDROGEN PEROXIDE; INTERLEUKIN 2; PHENOL DERIVATIVE; PICEA SITCHENSIS EXTRACT; PINUS BANKSIANA EXTRACT; PLANT EXTRACT; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ANTIOXIDANT ACTIVITY; ARTICLE; CELL DEATH; CELL LEVEL; CELL PROTECTION; CELL VIABILITY; CHEMICAL COMPOSITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DNA DAMAGE; DRUG ISOLATION; ENZYME ACTIVITY; FERRIC REDUCING ANTIOXIDANT POWER ASSAY; GAS CHROMATOGRAPHY; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; NONHUMAN; OXIDATIVE STRESS; PINUS BANKSIANA; PRIORITY JOURNAL; SITKA SPRUCE; TREE TRUNK;

ANTIOXIDANTS; CACO-2 CELLS; CELL DEATH; CELL LINE; CELL SURVIVAL; CELLS; HUMANS; PICEA; PINUS; PLANT BARK; PLANT EXTRACTS; WOOD;

PICEA SITCHENSIS; PINUS BANKSIANA;

EID: 74349127636     PISSN: 1096620X     EISSN: None     Source Type: Journal    
DOI: 10.1089/jmf.2008.0125     Document Type: Article

References (43)

1. Halliwell B, Cross CE: Oxygen-derived species: their relation to human disease and environmental stress. Environ Health Perspect 1994;102(Suppl 10):5-12.
2. Turley DB, Chaudhry Q, Watkins RW, et al.: Chemical products from temperate forest tree species-developing strategies for exploitation. Ind Crops Prod 2006;24:238-243.
3. Willför S, Ahotupa M, Hemming J, et al.: Antioxidant activity of knotwood extractives and phenolic compounds of selected tree species. J Agric Food Chem 2003;51:7600-7606.
4. Willför S, Sundberg A, Rehn P, et al.: Distribution of lignans in knots and adjacent stemwood of Picea abies. Hol Roh Werkstoff 2005;63:353-357.
5. Willför S, Hemming J, Reunanen M, et al.: Lignans and lipophilic extractives in Norway spruce knots and stemwood. Holzforschung 2003;57:27-36.
6. Benzie IFF, Strain JJ: Ferric reducing/antioxidant power assay: direct measure of total antioxidant activity of biological fluids and modified version for simultaneous measurement of total antioxidant power and ascorbic acid concentration. Methods Enzymol 1999;299:15-27.
7. Hissin PJ, Hilf R: A fluorometric method for determination of oxidized and reduced glutathione in tissues. Anal Biochem 1976;74:214-226.
8. Smith PK, Krohn RI, Hermanson GT, et al.: Measurement of protein using bicinchoninic acid. Anal Biochem 1985;150:76-85.
9. Tice RR, Andrews PW, Hirai O, et al.: The single cell gel (SCG) assay: an electrophoretic technique for the detection of DNA damage in individual cells. In: Biological and Reactive Intermediates IV (Witmer CM, editor). Plenum Press, New York, 1990, pp. 157-164.
10. Møller P: Assessment of reference values for DNA damage detected by the comet assay in human blood cell DNA. Mutat Res 2006;612:84-104.
11. Singleton V, Rossi J: Colorimetry of total phenolics with phosphomolybdic- phosphotungstic acid reagents. Am J Enol Vitic 1965;16:144-158.
12. Willför S, Hemming J, Reunanen M, et al.: Phenolic and lipophilic extractives in Scots pine knots and stemwood. Holzforschung 2003;57:359-372.
13. Thompson LU: Lignans and isoflavones. In: Carcinogenic/Anticarcinogenic Factors in Food (Eisenbrand G, Dayan AD, Elias PS, et al., eds). Wiley-VCH, Weinheim, Germany, 2000, pp. 334-337.
14. Arts IC, Hollman PC: Polyphenols and disease risk in epidemiologic studies. Am J Clin Nutr 2005;81(1 Suppl):317S-325S.
15. Zern TL, Fernandez ML: Cardioprotective effects of dietary polyphenols. J Nutr 2005;135:2291-2294.
16. Willför S, Eklund P, Sjoholm S, et al.: Bioactive phenolic substances in industrially important tree species. Part 4: Identification of two new 7-hydroxy divanillyl butyrolactol lignans in some spruce, fir, and pine species. Holzforschung 2005;59:413-417.
17. Johnston JW, Dussert S, Gale S, et al.: Optimisation of the azinobis- 3-ethyl-benzothiazoline-6-sulphonic acid radical scavenging assay for physiological studies of total antioxidant activity in woody plant germplasm. Plant Physiol Biochem 2006;44:193-201.
18. Pietarinen SP, Willför SM, Aotupa MO, et al.: Knotwood and bark extracts: strong antioxidants from waste materials. J Wood Sci 2006;52:436-444.
19. Neacsu M, Eklund PC, Sjöholm RE, et al.: Antioxidant flavonoids from knotwood of Jack pine and European aspen. Holz Roh Werkstoff 2007;65:1-6.
20. Aherne SA, Kerry JP, O'Brien NM: Effects of plant extracts on antioxidant status and oxidant-induced stress in Caco-2 cells. Br J Nutr 2007;97:321-328.
21. Vasilev NP, Ionkova I: Cytotoxic activity of extracts from linum cell cultures. Fitoterapia 2005;76:50-53.
22. Shashi B, Jaswant S, Madhusudana RJ, et al.: A novel lignan composition from Cedrus deodara induces apoptosis and early nitric oxide generation in human leukaemia Molt-4 and HL-60 cells. Nitric Oxide 2006;14:72-88.
23. Kang MH, Naito M, Sakai, K, et al.: Mode of action of sesame lignans in protecting low-density lipoprotein against oxidative damage in vitro. Life Sci 2000;66:161-171.
24. Suja KP, Jayalekshmy A: In vitro studies on antioxidant activity of lignans isolated from sesame cake extract. J Sci Food Agric 2005;85:1779-1783.
25. Owen RW, Mier W, Giacosa A, et al.: The antioxidant/anticancer potential of phenolic compounds isolated from olive oil. Eur J Cancer 2000;36:1235-1247.
26. Owen RW, Mier W, Giacosa A, et al.: Phenolic compounds and squalene in olive oils: the concentration and antioxidant potential of total phenols, simple phenols, secoiridoids, lignans and squalene. Food Chem Toxicol 2000;38:647-659.
27. Saarinen NM, Wärri A, Airio M, et al.: Role of dietary lignans in the reduction of breast cancer risk. Mol Nutr Food Res 2007;51:857-866.
28. Lanzilli G, Fuggetta MP, Tricarico M, et al.: Resveratrol downregulates the growth and telomerase activity of breast cancer cells in vitro. Int J Oncol 2006;28:641-648.
29. Rezk YA, Balulad SS, Keller RS, et al.: Use of resveratrol to improve the effectiveness of cisplatin and doxorubicin: study in human gynecologic cancer cell lines and in rodent heart. Am J Obst Gynecol 2006;194:E23-E26.
30. Ali MA, Debnath DC: Isolation and characterisation of ntibacterial constituent from devdaru (lignum of Polyalthia longifolia L.). Bangladesh J Sci Ind Res 1997;32:20-24.
31. Celimene CC, Micales JA, Ferge L, et al.: Efficacy of pinosylvins against white-rot and brown-rot fungi. Holzforschung 1999;53:491-497.
32. Lindberg LE, Willför SM, Holmbom BR: Antibacterial effects of knotwood extractives on paper mill bacteria. J Ind Microbiol Biotechnol 2004;31:137-147.
33. Nitta T, Arai T, Takamatsu H, et al.: Antibacterial activity of extracts prepared from torpical and subtropical plants on methicillin-restistant Staphyloccus aureus. J Health Sci 2002; 48:273-276.
34. Välimaa A-L, Honkalampi-Hämäläinen U, Petarinen S, et al.: Antimicrobial and cytotoxic knotwood extracts and related pure compounds and their effects on food-associated microorganisms. Int J Food Microbiol 2007;115:235-243.
35. Aherne SA, O'Brien NM: Modulation of cytokine production by plant sterols in stimulated human Jurkat T cells. Mol Nutr Food Res 2008;52:664-673.
36. Tanaka S, Akaishi E, Hosaka K, et al.: Zinc ions suppress mitogen-activated interleukin-2 production in Jurkat cells. Biochem Biophys Res Commun 2005;335:162-167.
37. Cho JY, Park J, Kim PS, et al.: Savinin, a lignan from Pterocarpus santalinus, inhibits tumor necrosis factor-alpha production and T cell proliferation. Biol Pharm Bull 2006;24: 167-171.
38. Duan H, Takaishi Y, Momota H, et al.: Immunosuppressive constituents from Saussurea medusa. Phytochemistry 2002;59: 85-90.
39. Kim JY, Lim HJ, Lee DY, et al.: In vitro anti-inflammatory activity of lignans isolated from Magnolia fargesii. Bioorg Med Chem Lett 2009;19:937-940.
40. Zhao F, Wang L, Liu K: In vitro anti-inflammatory effects of arctigenin, a lignan from Arctium lappa L., through inhibition on iNOS pathway. J Ethnopharmacol 2009;122:457-462.
41. Pandey R, Mauyra R, Singh G, et al.: Immunosuppressive properties of flavonoids isolated from Boerhaavia diffusa Linn. Int Immunopharmacol 2005;5:541-553.
42. Yeh S-L, Wang H-M, Chen P-Y, et al.: Interactions of bcarotene and flavonoids on secretion of pro-inflammatory mediators in an in vitro system. Chem Biol Interact 2009;179: 386-393.
43. Okoko T, Oruambo IF: Inhibitory activity of quercetin and its metabolite on lipopolysaccharide-induced activation of macrophage U937 cells. Food Chem Toxicol 2009;47:809-812.