-
1
-
-
0142166328
-
Cancer chemoprevention with dietary phytochemicals
-
Surh, Y. J. Cancer chemoprevention with dietary phytochemicals. Nat Rev Cancer 3, 768-780 (2003).
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 768-780
-
-
Surh, Y.J.1
-
2
-
-
27744511607
-
Use of cancer chemopreventive phytochemicals as antineoplastic agents
-
DOI 10.1016/S1470-2045(05)70425-3, PII S1470204505704253
-
D'Incalci, M., Steward, W. P. & Gescher, A. J. Use of cancer chemopreventive phytochemicals as antineoplastic agents. Lancet Oncol 6, 899-904 (2005). (Pubitemid 41614802)
-
(2005)
Lancet Oncology
, vol.6
, Issue.11
, pp. 899-904
-
-
D'Incalci, M.1
Steward, W.P.2
Gescher, A.J.3
-
3
-
-
33751072349
-
Resveratrol improves health and survival of mice on a high-calorie diet
-
DOI 10.1038/nature05354, PII NATURE05354
-
Baur, J. A. et al. Resveratrol improves health and survival of mice on a high-calorie diet. Nature 444, 337-342 (2006). (Pubitemid 44764104)
-
(2006)
Nature
, vol.444
, Issue.7117
, pp. 337-342
-
-
Baur, J.A.1
Pearson, K.J.2
Price, N.L.3
Jamieson, H.A.4
Lerin, C.5
Kalra, A.6
Prabhu, V.V.7
Allard, J.S.8
Lopez-Lluch, G.9
Lewis, K.10
Pistell, P.J.11
Poosala, S.12
Becker, K.G.13
Boss, O.14
Gwinn, D.15
Wang, M.16
Ramaswamy, S.17
Fishbein, K.W.18
Spencer, R.G.19
Lakatta, E.G.20
Le Couteur, D.21
Shaw, R.J.22
Navas, P.23
Puigserver, P.24
Ingram, D.K.25
De Cabo, R.26
Sinclair, D.A.27
more..
-
4
-
-
0038299558
-
Role of microRNAs in plant and animal development
-
DOI 10.1126/science.1085242
-
Carrington, J. & Ambros, V. Role of microRNAs in plant and animal development. Science 301, 336-338 (2003). (Pubitemid 36877060)
-
(2003)
Science
, vol.301
, Issue.5631
, pp. 336-338
-
-
Carrington, J.C.1
Ambros, V.2
-
5
-
-
0347444723
-
MicroRNAs: Genomics, biogenesis, mechanism, and function
-
Bartel, D. P. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116, 281-297 (2004).
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
6
-
-
4644309196
-
The functions of animal microRNAs
-
DOI 10.1038/nature02871
-
Ambros, V. The functions of animal microRNAs. Nature 431, 350-355 (2004). (Pubitemid 39265675)
-
(2004)
Nature
, vol.431
, Issue.7006
, pp. 350-355
-
-
Ambros, V.1
-
7
-
-
20444460289
-
MicroRNA expression profiles classify human cancers
-
DOI 10.1038/nature03702
-
Lu, J. et al. MicroRNA expression profiles classify human cancers. Nature 435, 834-838 (2005). (Pubitemid 40839735)
-
(2005)
Nature
, vol.435
, Issue.7043
, pp. 834-838
-
-
Lu, J.1
Getz, G.2
Miska, E.A.3
Alvarez-Saavedra, E.4
Lamb, J.5
Peck, D.6
Sweet-Cordero, A.7
Ebert, B.L.8
Mak, R.H.9
Ferrando, A.A.10
Downing, J.R.11
Jacks, T.12
Horvitz, H.R.13
Golub, T.R.14
-
8
-
-
79958277000
-
MicroRNA122 is a key regulator of a-fetoprotein expression and influences the aggressiveness of hepatocellular carcinoma
-
Kojima, K. et al.MicroRNA122 is a key regulator of a-fetoprotein expression and influences the aggressiveness of hepatocellular carcinoma. Nat Commun 2, 338 (2011).
-
(2011)
Nat Commun.
, vol.2
, pp. 338
-
-
Kojima, K.1
-
9
-
-
84872130380
-
MicroRNA-140 acts as a liver tumor suppressor by controlling NF-kB activity by directly targeting DNA methyltransferase 1 (Dnmt1) expression
-
Takata, A. et al. MicroRNA-140 acts as a liver tumor suppressor by controlling NF-kB activity by directly targeting DNA methyltransferase 1 (Dnmt1) expression. Hepatology 57, 162-170 (2013).
-
(2013)
Hepatology
, vol.57
, pp. 162-170
-
-
Takata, A.1
-
10
-
-
79959845414
-
MicroRNAs 103 and 107 regulate insulin sensitivity
-
Trajkovski, M. et al. MicroRNAs 103 and 107 regulate insulin sensitivity. Nature 474, 649-653 (2011).
-
(2011)
Nature
, vol.474
, pp. 649-653
-
-
Trajkovski, M.1
-
11
-
-
28444469246
-
Silencing ofmicroRNAs in vivo with 'antagomirs'
-
Krützfeldt, J. et al. Silencing ofmicroRNAs in vivo with 'antagomirs'. Nature 438, 685-689 (2005).
-
(2005)
Nature
, vol.438
, pp. 685-689
-
-
Krützfeldt, J.1
-
12
-
-
84862928682
-
Apigenin induces apoptosis in human leukemia cells and exhibits anti-leukemic activity in vivo
-
Budhraja, A. et al. Apigenin induces apoptosis in human leukemia cells and exhibits anti-leukemic activity in vivo. Mol Cancer Ther 11, 132-142 (2012).
-
(2012)
Mol Cancer Ther.
, vol.11
, pp. 132-142
-
-
Budhraja, A.1
-
13
-
-
34547114744
-
Blockade of β-catenin signaling by plant flavonoid apigenin suppresses prostate carcinogenesis in TRAMP mice
-
DOI 10.1158/0008-5472.CAN-07-0717
-
Shukla, S. et al. Blockade of beta-catenin signaling by plant flavonoid apigenin suppresses prostate carcinogenesis in TRAMP mice. Cancer Res 67, 6925-6935 (2007). (Pubitemid 47105540)
-
(2007)
Cancer Research
, vol.67
, Issue.14
, pp. 6925-6935
-
-
Shukla, S.1
MacLennan, G.T.2
Flask, C.A.3
Fu, P.4
Mishra, A.5
Resnick, M.I.6
Gupta, S.7
-
14
-
-
0033933197
-
Cell-cycle arrest at G2/M and growth inhibition by apigenin in human colon carcinoma cell lines
-
DOI 10.1002/1098-2744(200006)28:2<102::AID-MC6>3.0.CO;2-2
-
Wang, W. et al. Cell-cycle arrest at G2/M and growth inhibition by apigenin in human colon carcinoma cell lines. Mol Carcinog 28, 102-110 (2000). (Pubitemid 30432478)
-
(2000)
Molecular Carcinogenesis
, vol.28
, Issue.2
, pp. 102-110
-
-
Wang, W.1
Heideman, L.2
Chung, C.S.3
Pelling, J.C.4
Koehler, K.J.5
Birt, D.F.6
-
15
-
-
70349577785
-
Phosphorylation of the human microRNAgenerating complex mediates MAPK/Erk signaling
-
Paroo, Z., Ye, X., Chen, S. & Liu, Q. Phosphorylation of the human microRNAgenerating complex mediates MAPK/Erk signaling. Cell 139, 112-122 (2009).
-
(2009)
Cell
, vol.139
, pp. 112-122
-
-
Paroo, Z.1
Ye, X.2
Chen, S.3
Liu, Q.4
-
16
-
-
77956339082
-
The dietary flavonoid apigenin blocks phorbol 12-myristate 13-acetate-induced COX-2 transcriptional activity in breast cell lines
-
Yi Lau, G. T. & Leung, L. K. The dietary flavonoid apigenin blocks phorbol 12-myristate 13-acetate-induced COX-2 transcriptional activity in breast cell lines. Food Chem Toxicol 48, 3022-3027 (2010).
-
(2010)
Food Chem Toxicol
, vol.48
, pp. 3022-3027
-
-
Yi Lau, G.T.1
Leung, L.K.2
-
17
-
-
0035687569
-
Suppression by apigenin of peritoneal metastasis of intestinal adenocarcinomas induced by azoxymethane in Wistar rats
-
Tatsuta, A. et al. Suppression by apigenin of peritoneal metastasis of intestinal adenocarcinomas induced by azoxymethane in Wistar rats. Clin Exp Metastasis 18, 657-662 (2000).
-
(2000)
Clin Exp Metastasis
, vol.18
, pp. 657-662
-
-
Tatsuta, A.1
-
18
-
-
0032763752
-
Signal pathways involved in apigenin inhibition of growth and induction of apoptosis of human anaplastic thyroid cancer cells (ARO)
-
Yin, F., Giuliano, A. E. & Van Herle, A. J. Signal pathways involved in apigenin inhibition of growth and induction of apoptosis of human anaplastic thyroid cancer cells (ARO). Anticancer Res 19, 4297-4303 (1999).
-
(1999)
Anticancer Res.
, vol.19
, pp. 4297-4303
-
-
Yin, F.1
Giuliano, A.E.2
Van Herle, A.J.3
-
19
-
-
0029080674
-
Reversion of v-H-ras-transformed NIH 3T3 cells by apigenin through inhibitingmitogen activated protein kinase and its downstream oncogenes
-
Kuo, M. L. & Yang, N. C. Reversion of v-H-ras-transformed NIH 3T3 cells by apigenin through inhibitingmitogen activated protein kinase and its downstream oncogenes. Biochem Biophys Res Commun 212, 767-775 (1995).
-
(1995)
Biochem Biophys Res Commun
, vol.212
, pp. 767-775
-
-
Kuo, M.L.1
Yang, N.C.2
-
20
-
-
16044371194
-
Selective radiosensitization of p53-deficient cells by caffeinemediated activation of p34cdc2 kinase
-
Yao, S. L. et al. Selective radiosensitization of p53-deficient cells by caffeinemediated activation of p34cdc2 kinase. Nat Med 2, 1140-1143 (1996).
-
(1996)
Nat Med.
, vol.2
, pp. 1140-1143
-
-
Yao, S.L.1
-
21
-
-
84860797409
-
Apigenin induces apoptosis via tumor necrosis factor receptorand Bcl-2-mediated pathway and enhances susceptibility of head and neck squamous cell carcinoma to 5-fluorouracil and cisplatin
-
Chan, L. P. et al. Apigenin induces apoptosis via tumor necrosis factor receptorand Bcl-2-mediated pathway and enhances susceptibility of head and neck squamous cell carcinoma to 5-fluorouracil and cisplatin. Biochim Biophys Acta 1820, 1081-1091 (2012).
-
(2012)
Biochim Biophys Acta
, vol.1820
, pp. 1081-1091
-
-
Chan, L.P.1
-
22
-
-
84863197873
-
Apigenin induces apoptosis and blocks growth of medroxyprogesterone acetate-dependent BT-474 xenograft tumors
-
Mafuvadze, B., Liang, Y., Besch-Williford, C., Zhang, X. & Hyder, S. M. Apigenin induces apoptosis and blocks growth of medroxyprogesterone acetate-dependent BT-474 xenograft tumors. Horm Cancer 3, 160-171 (2012).
-
(2012)
Horm Cancer
, vol.3
, pp. 160-171
-
-
Mafuvadze, B.1
Liang, Y.2
Besch-Williford, C.3
Zhang, X.4
Hyder, S.M.5
-
23
-
-
38449107785
-
Apigenin blocks lipopolysaccharide-induced lethality in vivo and proinflammatory cytokines expression by inactivating NF-kappaB through the suppression of p65 phosphorylation
-
Nicholas, C. et al. Apigenin blocks lipopolysaccharide-induced lethality in vivo and proinflammatory cytokines expression by inactivating NF-kappaB through the suppression of p65 phosphorylation. J Immunol 179, 7121-7127 (2007).
-
(2007)
J Immunol
, vol.179
, pp. 7121-7127
-
-
Nicholas, C.1
-
24
-
-
0021259185
-
Modification of platelet function and arachidonic acid metabolism by bioflavonoids. Structure-activity relations
-
DOI 10.1016/0006-2952(84)90423-4
-
Landolfi, R., Mower, R. L. & Steiner, M. Modification of platelet function and arachidonic acid metabolism by bioflavonoids. Structure-activity relations. Biochem Pharmacol 33, 1525-1530 (1984). (Pubitemid 14105028)
-
(1984)
Biochemical Pharmacology
, vol.33
, Issue.9
, pp. 1525-1530
-
-
Landolfi, R.1
Mower, R.L.2
Steiner, M.3
-
25
-
-
84864761391
-
Essential metabolic, anti-inflammatory, and anti-tumorigenic functions of miR-122 in liver
-
Hsu, S. H. et al. Essential metabolic, anti-inflammatory, and anti-tumorigenic functions of miR-122 in liver. J Clin Invest 122, 2871-2883 (2012).
-
(2012)
J Clin Invest.
, vol.122
, pp. 2871-2883
-
-
Hsu, S.H.1
-
26
-
-
74249112787
-
Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infection
-
Lanford, R. E. et al. Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infection. Science 327, 198-201 (2010).
-
(2010)
Science
, vol.327
, pp. 198-201
-
-
Lanford, R.E.1
-
27
-
-
42249093319
-
LNA-mediated microRNA silencing in non-human primates
-
DOI 10.1038/nature06783, PII NATURE06783
-
Elmén, J. et al. LNA-mediated microRNA silencing in non-human primates. Nature 452, 896-899 (2008). (Pubitemid 351550859)
-
(2008)
Nature
, vol.452
, Issue.7189
, pp. 896-899
-
-
Elmen, J.1
Lindow, M.2
Schutz, S.3
Lawrence, M.4
Petri, A.5
Obad, S.6
Lindholm, M.7
Hedtjarn, M.8
Hansen, H.F.9
Berger, U.10
Gullans, S.11
Kearney, P.12
Sarnow, P.13
Straarup, E.M.14
Kauppinen, S.15
-
28
-
-
33645075443
-
MiR-122 regulation of lipid metabolism revealed by in vivo antisense targeting
-
Esau, C. et al.miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting. Cell Metab 3, 87-98 (2006).
-
(2006)
Cell Metab
, vol.3
, pp. 87-98
-
-
Esau, C.1
-
29
-
-
24644483623
-
Molecular biology: Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA
-
DOI 10.1126/science.1113329
-
Jopling, C. L., Yi, M., Lancaster, A. M., Lemon, S. M. & Sarnow, P. Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA. Science 309, 1577-1581 (2005). (Pubitemid 41266486)
-
(2005)
Science
, vol.309
, Issue.5740
, pp. 1577-1581
-
-
Jopling, C.L.1
Yi, M.2
Lancaster, A.M.3
Lemon, S.M.4
Sarnow, P.5
-
30
-
-
84869120708
-
Discovering the first microRNA-targeted drug
-
Lindow,M. & Kauppinen, S. Discovering the first microRNA-targeted drug. J Cell Biol 199, 407-412 (2012).
-
(2012)
J Cell Biol
, vol.199
, pp. 407-412
-
-
Lindowm1
Kauppinen, S.2
-
31
-
-
79959978259
-
Caffeine inhibits cell proliferation and regulates PKA/GSK3b pathways in U87MG human glioma cells
-
Ku, B. M. et al. Caffeine inhibits cell proliferation and regulates PKA/GSK3b pathways in U87MG human glioma cells. Mol Cells 31, 275-279 (2011).
-
(2011)
Mol Cells
, vol.31
, pp. 275-279
-
-
Ku, B.M.1
-
32
-
-
79953222993
-
Procya nidins are potent inhibitors of LOX-1: A new player in the French Paradox
-
Nishizuka, T. et al. Procya nidins are potent inhibitors of LOX-1: a new player in the French Paradox. Proc Jpn Acad Ser B Phys Biol Sci 87, 104-113 (2011).
-
(2011)
Proc Jpn Acad ser B Phys Biol Sci.
, vol.87
, pp. 104-113
-
-
Nishizuka, T.1
-
33
-
-
84865968044
-
Cytoprotective effect of chlorogenic acid against a-synucleinrelated toxicity in catecholaminergic PC12 cells
-
Teraoka, M. et al. Cytoprotective effect of chlorogenic acid against a-synucleinrelated toxicity in catecholaminergic PC12 cells. J Clin Biochem Nutr 51, 122-127 (2012).
-
(2012)
J Clin Biochem Nutr
, vol.51
, pp. 122-127
-
-
Teraoka, M.1
-
34
-
-
77953189137
-
Apigenin: A promising molecule for cancer prevention
-
Shukla, S. & Gupta, S. Apigenin: a promising molecule for cancer prevention. Pharm Res 27, 962-978 (2010).
-
(2010)
Pharm Res
, vol.27
, pp. 962-978
-
-
Shukla, S.1
Gupta, S.2
-
35
-
-
80051573524
-
MicroRNA-22 and microRNA-140 suppress NF-kB activity by regulating the expression of NF-kB coactivators
-
Takata, A. et al. MicroRNA-22 and microRNA-140 suppress NF-kB activity by regulating the expression of NF-kB coactivators. Biochem Biophys Res Commun 411, 826-831 (2011).
-
(2011)
Biochem Biophys Res Commun.
, vol.411
, pp. 826-831
-
-
Takata, A.1
-
36
-
-
79952280325
-
Oncogenic Ras abrogates MEK SUMOylation that suppresses the ERK pathway and cell transformation
-
Kubota, Y., O'Grady, P., Saito, H. & Takekawa, M. Oncogenic Ras abrogates MEK SUMOylation that suppresses the ERK pathway and cell transformation. Nat Cell Biol 13, 282-291 (2011).
-
(2011)
Nat Cell Biol.
, vol.13
, pp. 282-291
-
-
Kubota, Y.1
O'Grady, P.2
Saito, H.3
Takekawa, M.4
-
37
-
-
67749143728
-
Modulat ion of microRNA processing by p53
-
Suzuki, H. I. et al. Modulat ion of microRNA processing by p53. Nature 460, 529-533 (2009).
-
(2009)
Nature
, vol.460
, pp. 529-533
-
-
Suzuki, H.I.1
|