-
1
-
-
14944385553
-
Global cancer statistics, 2002
-
Parkin D, Bray F, Ferlay J, Pisani P. Global cancer statistics, 2002. CA Cancer J Clin 2005; 55: 74-108.
-
(2005)
CA Cancer J Clin
, vol.55
, pp. 74-108
-
-
Parkin, D.1
Bray, F.2
Ferlay, J.3
Pisani, P.4
-
2
-
-
0042968962
-
Molecular viral oncology of hepatocellular carcinoma
-
Block T, Mehta A, Fimmel C, Jordan R. Molecular viral oncology of hepatocellular carcinoma. Oncogene 2003; 22: 5093-5107.
-
(2003)
Oncogene
, vol.22
, pp. 5093-5107
-
-
Block, T.1
Mehta, A.2
Fimmel, C.3
Jordan, R.4
-
3
-
-
33745298519
-
Nuclear factor-kappaB in cancer development and progression
-
Karin M. Nuclear factor-kappaB in cancer development and progression. Nature 2006; 441: 431-436.
-
(2006)
Nature
, vol.441
, pp. 431-436
-
-
Karin, M.1
-
4
-
-
79751492851
-
NF-κB in the liver-linking injury, fibrosis and hepatocellular carcinoma
-
Luedde T, Schwabe RF. NF-κB in the liver-linking injury, fibrosis and hepatocellular carcinoma. Nat Rev Gastroenterol Hepatol 2011; 8: 108-118.
-
(2011)
Nat Rev Gastroenterol Hepatol
, vol.8
, pp. 108-118
-
-
Luedde, T.1
Schwabe, R.F.2
-
5
-
-
4644324186
-
NF-kappaB functions as a tumour promoter in inflammation-associated cancer
-
Pikarsky E, Porat R, Stein I, Abramovitch R, Amit S, Kasem S, et al. NF-kappaB functions as a tumour promoter in inflammation-associated cancer. Nature 2004; 431: 461-466.
-
(2004)
Nature
, vol.431
, pp. 461-466
-
-
Pikarsky, E.1
Porat, R.2
Stein, I.3
Abramovitch, R.4
Amit, S.5
Kasem, S.6
-
6
-
-
0035988849
-
Activation of NF-kappa B, AP-1 and STAT transcription factors is a frequent and early event in human hepatocellular carcinomas
-
Liu P, Kimmoun E, Legrand A, Sauvanet A, Degott C, Lardeux B, et al. Activation of NF-kappa B, AP-1 and STAT transcription factors is a frequent and early event in human hepatocellular carcinomas. J Hepatol 2002; 37: 63-71.
-
(2002)
J Hepatol
, vol.37
, pp. 63-71
-
-
Liu, P.1
Kimmoun, E.2
Legrand, A.3
Sauvanet, A.4
Degott, C.5
Lardeux, B.6
-
7
-
-
70349871321
-
MicroRNA expression, survival, and response to interferon in liver cancer
-
Ji J, Shi J, Budhu A, Yu Z, Forgues M, Roessler S, et al. MicroRNA expression, survival, and response to interferon in liver cancer. N Engl J Med 2009; 361: 1437-1447.
-
(2009)
N Engl J Med
, vol.361
, pp. 1437-1447
-
-
Ji, J.1
Shi, J.2
Budhu, A.3
Yu, Z.4
Forgues, M.5
Roessler, S.6
-
8
-
-
84856994812
-
Conflicting roles of molecules in hepatocarcinogenesis: paradigm or paradox
-
Feng GS. Conflicting roles of molecules in hepatocarcinogenesis: paradigm or paradox. Cancer Cell 2012; 21: 150-154.
-
(2012)
Cancer Cell
, vol.21
, pp. 150-154
-
-
Feng, G.S.1
-
9
-
-
58249088751
-
MicroRNAs: target recognition and regulatory functions
-
Bartel DP. MicroRNAs: target recognition and regulatory functions. Cell 2009; 136: 215-233.
-
(2009)
Cell
, vol.136
, pp. 215-233
-
-
Bartel, D.P.1
-
10
-
-
34447639973
-
Hypersusceptibility to vesicular stomatitis virus infection in Dicer1-deficient mice is due to impaired miR24 and miR93 expression
-
Otsuka M, Jing Q, Georgel P, New L, Chen J, Mols J, et al. Hypersusceptibility to vesicular stomatitis virus infection in Dicer1-deficient mice is due to impaired miR24 and miR93 expression. Immunity 2007; 27: 123-134.
-
(2007)
Immunity
, vol.27
, pp. 123-134
-
-
Otsuka, M.1
Jing, Q.2
Georgel, P.3
New, L.4
Chen, J.5
Mols, J.6
-
11
-
-
42949179661
-
Impaired microRNA processing causes corpus luteum insufficiency and infertility in mice
-
Otsuka M, Zheng M, Hayashi M, Lee JD, Yoshino O, Lin S, et al. Impaired microRNA processing causes corpus luteum insufficiency and infertility in mice. J Clin Invest 2008; 118: 1944-1954.
-
(2008)
J Clin Invest
, vol.118
, pp. 1944-1954
-
-
Otsuka, M.1
Zheng, M.2
Hayashi, M.3
Lee, J.D.4
Yoshino, O.5
Lin, S.6
-
12
-
-
79958277000
-
MicroRNA122 is a key regulator of α-fetoprotein expression and influences the aggressiveness of hepatocellular carcinoma
-
Kojima K, Takata A, Vadnais C, Otsuka M, Yoshikawa T, Akanuma M, et al. MicroRNA122 is a key regulator of α-fetoprotein expression and influences the aggressiveness of hepatocellular carcinoma. Nat Commun 2011; 2: 338.
-
(2011)
Nat Commun
, vol.2
, pp. 338
-
-
Kojima, K.1
Takata, A.2
Vadnais, C.3
Otsuka, M.4
Yoshikawa, T.5
Akanuma, M.6
-
13
-
-
37549008310
-
Widespread microRNA repression by Myc contributes to tumorigenesis
-
Chang T-C, Yu D, Lee Y-S, Wentzel EA, Arking DE, West KM, et al. Widespread microRNA repression by Myc contributes to tumorigenesis. Nat Genet 2008; 40: 43-50.
-
(2008)
Nat Genet
, vol.40
, pp. 43-50
-
-
Chang, T.-C.1
Yu, D.2
Lee, Y.-S.3
Wentzel, E.A.4
Arking, D.E.5
West, K.M.6
-
14
-
-
20444460289
-
MicroRNA expression profiles classify human cancers
-
Lu J, Getz G, Miska EA, Alvarez-Saavedra E, Lamb J, Peck D, et al. MicroRNA expression profiles classify human cancers. Nature 2005; 435: 834-838.
-
(2005)
Nature
, vol.435
, pp. 834-838
-
-
Lu, J.1
Getz, G.2
Miska, E.A.3
Alvarez-Saavedra, E.4
Lamb, J.5
Peck, D.6
-
15
-
-
33750370444
-
MicroRNA signatures in human cancers
-
Calin GA, Croce CM. MicroRNA signatures in human cancers. Nat Rev Cancer 2006; 6: 857-866.
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 857-866
-
-
Calin, G.A.1
Croce, C.M.2
-
16
-
-
34047270440
-
Characterization of microRNA expression levels and their biological correlates in human cancer cell lines
-
Gaur A, Jewell DA, Liang Y, Ridzon D, Moore JH, Chen C, et al. Characterization of microRNA expression levels and their biological correlates in human cancer cell lines. Cancer Res 2007; 67: 2456-2468.
-
(2007)
Cancer Res
, vol.67
, pp. 2456-2468
-
-
Gaur, A.1
Jewell, D.A.2
Liang, Y.3
Ridzon, D.4
Moore, J.H.5
Chen, C.6
-
17
-
-
34247593034
-
Impaired microRNA processing enhances cellular transformation and tumorigenesis
-
Kumar MS, Lu J, Mercer KL, Golub TR, Jacks T. Impaired microRNA processing enhances cellular transformation and tumorigenesis. Nat Genet 2007; 39: 673-677.
-
(2007)
Nat Genet
, vol.39
, pp. 673-677
-
-
Kumar, M.S.1
Lu, J.2
Mercer, K.L.3
Golub, T.R.4
Jacks, T.5
-
18
-
-
77949541928
-
Monoallelic but not biallelic loss of Dicer1 promotes tumorigenesis in vivo
-
Lambertz I, Nittner D, Mestdagh P, Denecker G, Vandesompele J, Dyer MA, et al. Monoallelic but not biallelic loss of Dicer1 promotes tumorigenesis in vivo. Cell Death Differ 2010; 17: 633-641.
-
(2010)
Cell Death Differ
, vol.17
, pp. 633-641
-
-
Lambertz, I.1
Nittner, D.2
Mestdagh, P.3
Denecker, G.4
Vandesompele, J.5
Dyer, M.A.6
-
19
-
-
80052851349
-
Receptor for activated protein kinase C: requirement for efficient microRNA function and reduced expression in hepatocellular carcinoma
-
Otsuka M, Takata A, Yoshikawa T, Kojima K, Kishikawa T, Shibata C, et al. Receptor for activated protein kinase C: requirement for efficient microRNA function and reduced expression in hepatocellular carcinoma. PLoS One 2011; 6: e24359.
-
(2011)
PLoS One
, vol.6
-
-
Otsuka, M.1
Takata, A.2
Yoshikawa, T.3
Kojima, K.4
Kishikawa, T.5
Shibata, C.6
-
20
-
-
38349191617
-
CpG island hypermethylation of tumor suppressor microRNAs in human cancer
-
Lujambio A, Esteller M. CpG island hypermethylation of tumor suppressor microRNAs in human cancer. Cell Cycle 2007; 6: 1455-1459.
-
(2007)
Cell Cycle
, vol.6
, pp. 1455-1459
-
-
Lujambio, A.1
Esteller, M.2
-
21
-
-
33747334621
-
Extensive post-transcriptional regulation of microRNAs and its implications for cancer
-
Thomson J, Newman M, Parker J, Morin-Kensicki E, Wright T, Hammond S. Extensive post-transcriptional regulation of microRNAs and its implications for cancer. Genes Dev 2006; 20: 2202-2207.
-
(2006)
Genes Dev
, vol.20
, pp. 2202-2207
-
-
Thomson, J.1
Newman, M.2
Parker, J.3
Morin-Kensicki, E.4
Wright, T.5
Hammond, S.6
-
22
-
-
61349127117
-
A TARBP2 mutation in human cancer impairs microRNA processing and DICER1 function
-
Melo SA, Ropero S, Moutinho C, Aaltonen LA, Yamamoto H, Calin GA, et al. A TARBP2 mutation in human cancer impairs microRNA processing and DICER1 function. Nat Genet 2009; 41: 365-370.
-
(2009)
Nat Genet
, vol.41
, pp. 365-370
-
-
Melo, S.A.1
Ropero, S.2
Moutinho, C.3
Aaltonen, L.A.4
Yamamoto, H.5
Calin, G.A.6
-
23
-
-
84859611110
-
A miRNA machinery component DDX20 controls NF-κB via microRNA-140 function
-
Takata A, Otsuka M, Yoshikawa T, Kishikawa T, Kudo Y, Goto T, et al. A miRNA machinery component DDX20 controls NF-κB via microRNA-140 function. Biochem Biophys Res Commun 2012; 13: 564-569.
-
(2012)
Biochem Biophys Res Commun
, vol.13
, pp. 564-569
-
-
Takata, A.1
Otsuka, M.2
Yoshikawa, T.3
Kishikawa, T.4
Kudo, Y.5
Goto, T.6
-
24
-
-
77953067173
-
MicroRNA-140 plays dual roles in both cartilage development and homeostasis
-
Miyaki S, Sato T, Inoue A, Otsuki S, Ito Y, Yokoyama S, et al. MicroRNA-140 plays dual roles in both cartilage development and homeostasis. Genes Dev 2010; 24: 1173-1185.
-
(2010)
Genes Dev
, vol.24
, pp. 1173-1185
-
-
Miyaki, S.1
Sato, T.2
Inoue, A.3
Otsuki, S.4
Ito, Y.5
Yokoyama, S.6
-
25
-
-
73949118737
-
MicroRNA 29b functions in acute myeloid leukemia
-
Garzon R, Heaphy CE, Havelange V, Fabbri M, Volinia S, Tsao T, et al. MicroRNA 29b functions in acute myeloid leukemia. Blood 2009; 114: 5331-5341.
-
(2009)
Blood
, vol.114
, pp. 5331-5341
-
-
Garzon, R.1
Heaphy, C.E.2
Havelange, V.3
Fabbri, M.4
Volinia, S.5
Tsao, T.6
-
26
-
-
0037087780
-
miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs
-
Mourelatos Z, Dostie J, Paushkin S, Sharma A, Charroux B, Abel L, et al. miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs. Genes Dev 2002; 16: 720-728.
-
(2002)
Genes Dev
, vol.16
, pp. 720-728
-
-
Mourelatos, Z.1
Dostie, J.2
Paushkin, S.3
Sharma, A.4
Charroux, B.5
Abel, L.6
-
27
-
-
56349121125
-
An oncogenomics-based in vivo RNAi screen identifies tumor suppressors in liver cancer
-
Zender L, Xue W, Zuber J, Semighini C, Krasnitz A, Ma B, et al. An oncogenomics-based in vivo RNAi screen identifies tumor suppressors in liver cancer. Cell 2008; 135: 852-864.
-
(2008)
Cell
, vol.135
, pp. 852-864
-
-
Zender, L.1
Xue, W.2
Zuber, J.3
Semighini, C.4
Krasnitz, A.5
Ma, B.6
-
28
-
-
42449112525
-
DEAD-box protein-103 (DP103, Ddx20) is essential for early embryonic development and modulates ovarian morphology and function
-
Mouillet J, Yan X, Ou Q, Jin L, Muglia L, Crawford P, et al. DEAD-box protein-103 (DP103, Ddx20) is essential for early embryonic development and modulates ovarian morphology and function. Endocrinology 2008; 149: 2168-2175.
-
(2008)
Endocrinology
, vol.149
, pp. 2168-2175
-
-
Mouillet, J.1
Yan, X.2
Ou, Q.3
Jin, L.4
Muglia, L.5
Crawford, P.6
-
29
-
-
0035158971
-
Functional cooperation of Epstein-Barr virus nuclear antigen 2 and the survival motor neuron protein in transactivation of the viral LMP1 promoter
-
Voss M, Hille A, Barth S, Spurk A, Hennrich F, Holzer D, et al. Functional cooperation of Epstein-Barr virus nuclear antigen 2 and the survival motor neuron protein in transactivation of the viral LMP1 promoter. J Virol 2001; 75: 11781-11790.
-
(2001)
J Virol
, vol.75
, pp. 11781-11790
-
-
Voss, M.1
Hille, A.2
Barth, S.3
Spurk, A.4
Hennrich, F.5
Holzer, D.6
-
30
-
-
0033552589
-
Gemin3: a novel DEAD box protein that interacts with SMN, the spinal muscular atrophy gene product, and is a component of gems
-
Charroux B, Pellizzoni L, Perkinson R, Shevchenko A, Mann M, Dreyfuss G. Gemin3: a novel DEAD box protein that interacts with SMN, the spinal muscular atrophy gene product, and is a component of gems. J Cell Biol 1999; 147: 1181-1194.
-
(1999)
J Cell Biol
, vol.147
, pp. 1181-1194
-
-
Charroux, B.1
Pellizzoni, L.2
Perkinson, R.3
Shevchenko, A.4
Mann, M.5
Dreyfuss, G.6
-
31
-
-
0037144546
-
A microRNA in a multiple-turnover RNAi enzyme complex
-
Hutvágner G, Zamore P. A microRNA in a multiple-turnover RNAi enzyme complex. Science 2002; 297: 2056-2060.
-
(2002)
Science
, vol.297
, pp. 2056-2060
-
-
Hutvágner, G.1
Zamore, P.2
-
32
-
-
80051573524
-
MicroRNA-22 and microRNA-140 suppress NF-κB activity by regulating the expression of NF-κB coactivators
-
Takata A, Otsuka M, Kojima K, Yoshikawa T, Kishikawa T, Yoshida H, et al. MicroRNA-22 and microRNA-140 suppress NF-κB activity by regulating the expression of NF-κB coactivators. Biochem Biophys Res Commun 2011; 411: 826-831.
-
(2011)
Biochem Biophys Res Commun
, vol.411
, pp. 826-831
-
-
Takata, A.1
Otsuka, M.2
Kojima, K.3
Yoshikawa, T.4
Kishikawa, T.5
Yoshida, H.6
-
33
-
-
0032697485
-
Tumor necrosis factor-related apoptosis-inducing ligand receptors signal NF-kappaB and JNK activation and apoptosis through distinct pathways
-
Hu W, Johnson H, Shu H. Tumor necrosis factor-related apoptosis-inducing ligand receptors signal NF-kappaB and JNK activation and apoptosis through distinct pathways. J Biol Chem 1999; 274: 30603-30610.
-
(1999)
J Biol Chem
, vol.274
, pp. 30603-30610
-
-
Hu, W.1
Johnson, H.2
Shu, H.3
-
34
-
-
0345276580
-
Metallothioneins in human tumors and potential roles in carcinogenesis
-
Cherian MG, Jayasurya A, Bay BH. Metallothioneins in human tumors and potential roles in carcinogenesis. Mutat Res 2003; 533: 201-209.
-
(2003)
Mutat Res
, vol.533
, pp. 201-209
-
-
Cherian, M.G.1
Jayasurya, A.2
Bay, B.H.3
-
35
-
-
0036679202
-
Metallothionein expression in hepatocellular carcinoma
-
Huang GW, Yang LY. Metallothionein expression in hepatocellular carcinoma. World J Gastroenterol 2002; 8: 650-653.
-
(2002)
World J Gastroenterol
, vol.8
, pp. 650-653
-
-
Huang, G.W.1
Yang, L.Y.2
-
36
-
-
34047263219
-
Metallothionein expression is suppressed in primary human hepatocellular carcinomas and is mediated through inactivation of CCAAT/enhancer binding protein alpha by phosphatidylinositol 3-kinase signaling cascade
-
Datta J, Majumder S, Kutay H, Motiwala T, Frankel W, Costa R, et al. Metallothionein expression is suppressed in primary human hepatocellular carcinomas and is mediated through inactivation of CCAAT/enhancer binding protein alpha by phosphatidylinositol 3-kinase signaling cascade. Cancer Res 2007; 67: 2736-2746.
-
(2007)
Cancer Res
, vol.67
, pp. 2736-2746
-
-
Datta, J.1
Majumder, S.2
Kutay, H.3
Motiwala, T.4
Frankel, W.5
Costa, R.6
-
37
-
-
78650396121
-
Loss of metallothionein predisposes mice to diethylnitrosamine-induced hepatocarcinogenesis by activating NF-kappaB target genes
-
Majumder S, Roy S, Kaffenberger T, Wang B, Costinean S, Frankel W, et al. Loss of metallothionein predisposes mice to diethylnitrosamine-induced hepatocarcinogenesis by activating NF-kappaB target genes. Cancer Res 2010; 70: 10265-10276.
-
(2010)
Cancer Res
, vol.70
, pp. 10265-10276
-
-
Majumder, S.1
Roy, S.2
Kaffenberger, T.3
Wang, B.4
Costinean, S.5
Frankel, W.6
-
38
-
-
0034614381
-
Suppression of metallothionein gene expression in a rat hepatoma because of promoter-specific DNA methylation
-
Ghoshal K, Majumder S, Li Z, Dong X, Jacob ST. Suppression of metallothionein gene expression in a rat hepatoma because of promoter-specific DNA methylation. J Biol Chem 2000; 275: 539-547.
-
(2000)
J Biol Chem
, vol.275
, pp. 539-547
-
-
Ghoshal, K.1
Majumder, S.2
Li, Z.3
Dong, X.4
Jacob, S.T.5
-
40
-
-
0027378582
-
Role for DNA methylation in genomic imprinting
-
Li E, Beard C, Jaenisch R. Role for DNA methylation in genomic imprinting. Nature 1993; 366: 362-365.
-
(1993)
Nature
, vol.366
, pp. 362-365
-
-
Li, E.1
Beard, C.2
Jaenisch, R.3
-
41
-
-
33645690762
-
Epigenetic regulation of metallothionein-i gene expression: differential regulation of methylated and unmethylated promoters by DNA methyltransferases and methyl CpG binding proteins
-
Majumder S, Kutay H, Datta J, Summers D, Jacob ST, Ghoshal K. Epigenetic regulation of metallothionein-i gene expression: differential regulation of methylated and unmethylated promoters by DNA methyltransferases and methyl CpG binding proteins. J Cell Biochem 2006; 97: 1300-1316.
-
(2006)
J Cell Biochem
, vol.97
, pp. 1300-1316
-
-
Majumder, S.1
Kutay, H.2
Datta, J.3
Summers, D.4
Jacob, S.T.5
Ghoshal, K.6
-
43
-
-
58049213696
-
Dicer, Drosha, and outcomes in patients with ovarian cancer
-
Merritt W, Lin Y, Han L, Kamat A, Spannuth W, Schmandt R, et al. Dicer, Drosha, and outcomes in patients with ovarian cancer. N Engl J Med 2008; 359: 2641-2650.
-
(2008)
N Engl J Med
, vol.359
, pp. 2641-2650
-
-
Merritt, W.1
Lin, Y.2
Han, L.3
Kamat, A.4
Spannuth, W.5
Schmandt, R.6
-
44
-
-
59449098051
-
Single nucleotide polymorphisms of microRNA machinery genes modify the risk of renal cell carcinoma
-
Horikawa Y, Wood CG, Yang H, Zhao H, Ye Y, Gu J, et al. Single nucleotide polymorphisms of microRNA machinery genes modify the risk of renal cell carcinoma. Clin Cancer Res 2008; 14: 7956-7962.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 7956-7962
-
-
Horikawa, Y.1
Wood, C.G.2
Yang, H.3
Zhao, H.4
Ye, Y.5
Gu, J.6
-
45
-
-
42049114643
-
Evaluation of genetic variants in microRNA-related genes and risk of bladder cancer
-
Yang H, Dinney CP, Ye Y, Zhu Y, Grossman HB, Wu X. Evaluation of genetic variants in microRNA-related genes and risk of bladder cancer. Cancer Res 2008; 68: 2530-2537.
-
(2008)
Cancer Res
, vol.68
, pp. 2530-2537
-
-
Yang, H.1
Dinney, C.P.2
Ye, Y.3
Zhu, Y.4
Grossman, H.B.5
Wu, X.6
-
46
-
-
64649087510
-
NF-kappaB inhibition in human hepatocellular carcinoma and its potential as adjunct to sorafenib based therapy
-
Wu JM, Sheng H, Saxena R, Skill NJ, Bhat-Nakshatri P, Yu M, et al. NF-kappaB inhibition in human hepatocellular carcinoma and its potential as adjunct to sorafenib based therapy. Cancer Lett 2009; 278: 145-155.
-
(2009)
Cancer Lett
, vol.278
, pp. 145-155
-
-
Wu, J.M.1
Sheng, H.2
Saxena, R.3
Skill, N.J.4
Bhat-Nakshatri, P.5
Yu, M.6
-
47
-
-
33746234769
-
Rapid and sensitive detection of CpG-methylation using methyl-binding (MB)-PCR
-
Gebhard C, Schwarzfischer L, Pham T, Andreesen R, Mackensen A, Rehli M. Rapid and sensitive detection of CpG-methylation using methyl-binding (MB)-PCR. Nucleic Acids Res 2006; 34: e82.
-
(2006)
Nucleic Acids Res
, vol.34
-
-
Gebhard, C.1
Schwarzfischer, L.2
Pham, T.3
Andreesen, R.4
Mackensen, A.5
Rehli, M.6
-
48
-
-
77953898940
-
A microRNA targeting dicer for metastasis control
-
Martello G, Rosato A, Ferrari F, Manfrin A, Cordenonsi M, Dupont S, et al. A microRNA targeting dicer for metastasis control. Cell 2010; 141: 1195-1207.
-
(2010)
Cell
, vol.141
, pp. 1195-1207
-
-
Martello, G.1
Rosato, A.2
Ferrari, F.3
Manfrin, A.4
Cordenonsi, M.5
Dupont, S.6
|