The curry spice curcumin attenuates beta-amyloid-induced toxicity through beta-catenin and PI3K signaling in rat organotypic hippocampal slice culture

Neurological Research

Volumn 35, Issue 8, 2013, Pages 857-866

  Hoppe, Juliana Bender ^a   Frozza, Rudimar Luiz ^b   Pires, Elisa Nicoloso Simões ^a   Meneghetti, André Bevilacqua ^a   Salbego, Christianne ^a  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

Beta amyloid; Beta catenin; Curcumin; Organotypic hippocampal slice culture; PI3K signaling pathway

Indexed keywords

AMYLOID BETA PROTEIN; BETA CATENIN; CURCUMIN; GLYCOGEN SYNTHASE KINASE 3BETA; INTERLEUKIN 10; INTERLEUKIN 6; OXYGEN RADICAL; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; SYNAPTOPHYSIN;

ALZHEIMER DISEASE; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL ASSAY; CELL DAMAGE; CELL DEATH; CELL SURVIVAL; CYTOTOXICITY; HIPPOCAMPUS; IMMUNOFLUORESCENCE; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PROTEIN PHOSPHORYLATION; QUANTITATIVE ANALYSIS; RAT; SLICE CULTURE; SYNAPTIC DYSFUNCTION; WESTERN BLOTTING; WNT SIGNALING PATHWAY;

AMYLOID BETA-PEPTIDES; ANIMALS; BETA CATENIN; CELL DEATH; CHROMONES; CURCUMIN; GLYCOGEN SYNTHASE KINASE 3; HIPPOCAMPUS; INTERLEUKIN-10; INTERLEUKIN-6; MALE; MORPHOLINES; NEUROPROTECTIVE AGENTS; PEPTIDE FRAGMENTS; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RATS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SYNAPTIC TRANSMISSION; SYNAPTOPHYSIN;

EID: 84884172219     PISSN: 01616412     EISSN: 17431328     Source Type: Journal    
DOI: 10.1179/1743132813Y.0000000225     Document Type: Article

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