BMP9 and COX-2 form an important regulatory loop in BMP9-induced osteogenic differentiation of mesenchymal stem cells

Bone

Volumn 57, Issue 1, 2013, Pages 311-321

  Wang, Jin Hua ^a,b   Liu, Ying Zi ^b,c   Yin, Liang Jun ^b   Chen, Liang ^b   Huang, Jun ^b,c   Liu, Yang ^b   Zhang, Ran Xi ^b,c   Zhou, Long Yang ^b,c   Yang, Qiu Jun ^b,c   Luo, Jin Yong ^b   Zuo, Guo wei ^b   Deng, Zhong Liang ^b   He, Bai Cheng ^b,c  

^a Chongqing Research Center for Oral Diseases and Biomedical Science   (China)

^b CHONGQING MEDICAL UNIVERSITY   (China)

^c Chongqing Key Laboratory of Biochemistry and Molecular Pharmacology   (China)

Author keywords

BMP Smad signaling; BMP9; COX 2; Mesenchymal stem cells; Osteogenic differentiation

Indexed keywords

ALKALINE PHOSPHATASE; BONE MORPHOGENETIC PROTEIN 9; BONE MORPHOGENETIC PROTEIN RECEPTOR; CYCLOOXYGENASE 2; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; OSTEOCALCIN; OSTEOPONTIN; SMAD PROTEIN; SMAD1 PROTEIN; SMAD5 PROTEIN; SMAD6 PROTEIN; SMAD7 PROTEIN; SMAD8 PROTEIN; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR DLX5; TRANSCRIPTION FACTOR RUNX2;

ADENOVIRUS; ANIMAL CELL; ARTICLE; BONE DEVELOPMENT; BONE MINERALIZATION; CARTILAGE CELL; CELL DIFFERENTIATION; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; ENZYME ACTIVITY; GENE EXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; IN VIVO STUDY; MESENCHYMAL STEM CELL; MOUSE; NONHUMAN; OSSIFICATION; OSTEOBLAST; PHARMACOLOGICAL BLOCKING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; UPREGULATION;

BMP/SMAD SIGNALING; BMP9; COX-2; MESENCHYMAL STEM CELLS; OSTEOGENIC DIFFERENTIATION;

ANIMALS; CELL DIFFERENTIATION; CELL LINE; CELLS, CULTURED; CHROMATIN IMMUNOPRECIPITATION; CYCLOOXYGENASE 2; GROWTH DIFFERENTIATION FACTOR 2; HUMANS; MESENCHYMAL STROMAL CELLS; MICE;

EID: 84884167287     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2013.08.015     Document Type: Article

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