Growth hormone synergizes with BMP9 in osteogenic differentiation by activating the JAK/STAT/IGF1 pathway in murine multilineage cells

Journal of Bone and Mineral Research

Volumn 27, Issue 7, 2012, Pages 1566-1575

  Huang, Enyi ^a,b   Zhu, Gaohui ^b,c   Jiang, Wei ^b   Yang, Ke ^b,d   Gao, Yanhong ^b,e   Luo, Qing ^b,c   Gao, Jian Li ^b,f   Kim, Stephanie H ^b   Liu, Xing ^b,c   Li, Mi ^b,c   Shi, Qiong ^b,g   Hu, Ning ^b,g   Wang, Linyuan ^b   Liu, Hong ^b,g   Cui, Jing ^b,g   Zhang, Wenwen ^b,g   Li, Ruidong ^b,g   Chen, Xiang ^b,h   Kong, Yu Han ^b,g   Zhang, Jiye ^b,g   Wang, Jinhua ^b,g   Shen, Jikun ^b   Bi, Yang ^b,c   Statz, Joseph ^b   He, Bai Cheng ^b,g   Luo, Jinyong ^b,g   Wang, Huicong ^a   Xiong, Feng ^c   Luu, Hue H ^b   Haydon, Rex C ^b   Yang, Li ^a   He, Tong Chuan ^b,c   more..

^a CHONGQING UNIVERSITY   (China)

^b UNIVERSITY OF CHICAGO MEDICAL CENTER   (United States)

^c CHILDREN S HOSPITAL OF CHONGQING MEDICAL UNIVERSITY   (China)

^d THIRD MILITARY MEDICAL UNIVERSITY   (China)

^e SHANGHAI JIAO TONG UNIVERSITY   (China)

^f ZHEJIANG CHINESE MEDICAL UNIVERSITY   (China)

^g CHONGQING MEDICAL UNIVERSITY   (China)

^h FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

BMP9 signaling; Extrapituitary growth hormone; JAK STAT IGF1 pathway; Mesenchymal stem cells; Osteogenic differentiation

Indexed keywords

BONE MORPHOGENETIC PROTEIN 9; GROWTH HORMONE; JANUS KINASE; SOMATOMEDIN C; STAT PROTEIN;

ANIMAL CELL; ARTICLE; BONE DEVELOPMENT; BONE MATURATION; CELL DIFFERENTIATION; CELL LINEAGE; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; EXPLANT; GENE CONTROL; GENE EXPRESSION PROFILING; GROWTH PLATE; HORMONAL REGULATION; MOUSE; MULTIPOTENT STEM CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; OSSIFICATION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ANIMALS; CELL LINEAGE; FEMALE; FIBROBLASTS; GENE EXPRESSION REGULATION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GROWTH DIFFERENTIATION FACTOR 2; GROWTH DIFFERENTIATION FACTORS; GROWTH HORMONE; HUMANS; INSULIN-LIKE GROWTH FACTOR I; JANUS KINASE 1; MICE; MICE, INBRED C3H; OSTEOGENESIS; SIGNAL TRANSDUCTION; STAT TRANSCRIPTION FACTORS;

EID: 84862490688     PISSN: 08840431     EISSN: 15234681     Source Type: Journal    
DOI: 10.1002/jbmr.1622     Document Type: Article

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