BMP9 inhibits the proliferation and invasiveness of breast cancer cells MDA-MB-231

Journal of Cancer Research and Clinical Oncology

Volumn 137, Issue 11, 2011, Pages 1687-1696

  Wang, Ke ^a   Feng, Honglei ^a   Ren, Wei ^a   Sun, Xiaoxiao ^a   Luo, Jinyong ^a   Tang, Min ^a   Zhou, Lan ^a   Weng, Yaguang ^a   He, Tong Chuan ^b   Zhang, Yan ^a  

^a CHONGQING MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF CHICAGO MEDICAL CENTER   (United States)

Author keywords

BMP9; Breast cancer; Invasion; Proliferation

Indexed keywords

BONE MORPHOGENETIC PROTEIN 9; CYCLINE; DNA NUCLEOTIDYLEXOTRANSFERASE; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL; CANCER INHIBITION; CANCER PATIENT; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; CLINICAL ARTICLE; COLONY FORMATION; CONTROLLED STUDY; FEMALE; GENE AMPLIFICATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; TUMOR GROWTH;

ANIMALS; APOPTOSIS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; FEMALE; GROWTH DIFFERENTIATION FACTORS; HUMANS; MICE; MICE, NUDE; NEOPLASM INVASIVENESS; NEOPLASM TRANSPLANTATION; RNA, MESSENGER; TRANSPLANTATION, HETEROLOGOUS;

EID: 80054723100     PISSN: 01715216     EISSN: 14321335     Source Type: Journal    
DOI: 10.1007/s00432-011-1047-4     Document Type: Article

References (22)

1. EL Alarmo T Korhonen 2008 Bone morphogenetic protein 7 expression associates with bone metastasis in breast carcinomas Ann Oncol 19 308 314 17895257 10.1093/annonc/mdm453 (Pubitemid 351201712)
2. EL Alarmo J Parssinen JM Ketolainen, et al. 2009 BMP7 influences proliferation, migration, and invasion of breast cancer cells Cancer Lett 275 35 43 18980801 10.1016/j.canlet.2008.09.028 1:CAS:528:DC%2BD1MXhtVeiurg%3D
3. H Blanca D van Maarten D ten Peter, et al. 2009 Autocrine bone morphogenetic protein-9 signals through activin receptor-like Kinase-2/Smad1/Smad4 to promote ovarian cancer cell proliferation Cancer Res 69 9254 9262 10.1158/0008-5472.CAN-09-2912
4. JT Buijs NV Henriquez PGM van Overveld, et al. 2007 Bone morphogenetic protein 7 in the development and treatment of bone metastases from breast cancer Cancer Res 67 8742 8751 17875715 10.1158/0008-5472.CAN-06-2490 1:CAS:528:DC%2BD2sXhtVCit7vK (Pubitemid 47437450)
5. AJ Celeste JJ Song K Cox, et al. 1994 Bone morphogenetic protein-9, a new member of the TGF-β superfamily J Bone Miner Res Suppl1 136
6. H Cheng W Jiang FM Phillips, et al. 2003 Osteogenic Activity of the 14 Types of Human Bone Morphogenetic Proteins (BMPs) Journal of Bone and Joint Surgery 85 1544 1552 12925636 (Pubitemid 36951140)
7. J Du S Yang Z Wang, et al. 2008 Bone morphogenetic protein 6 inhibit stress-induced breast cancer cells apoptosis via both Smad and p38 pathways J Cell Biochem 103 1584 1597 17879955 10.1002/jcb.21547 1:CAS:528: DC%2BD1cXkslShsL4%3D (Pubitemid 351490724)
8. XH Feng R Derynck 2005 Specificity and versatility in tgf-beta signaling through Smads Annu Rev Cell Dev Bio 21 659 693 10.1146/annurev.cellbio.21. 022404.142018 1:CAS:528:DC%2BD2MXhtlektbjM (Pubitemid 41740650)
9. S Hatakeyama Y Ohara-Nemoto S Kyakumoto, et al. 1993 Expression of bone morphoenetic protein in human adencarcinoma cell line Biochem Biophys Res Commun 190 695 701 8439320 10.1006/bbrc.1993.1105 1:CAS:528:DyaK3sXhs1Kgtbc%3D (Pubitemid 23207821)
10. Y Katsuno A Hanyu H Kanda, et al. 2008 Bone morphogenetic protein signaling enhances invasion and bone metastasis of breast cancer cells through Smad pathway Oncogene 27 6322 6333 18663362 10.1038/onc.2008.232 1:CAS:528:DC%2BD1cXht1Ont7fM
11. IY Kim DH Lee HJ Ahn, et al. 2000 Expression of bone morphogenetic protein receptors type IA,- IB and-II correlates with tumor grade in human prostate cancer tissues Cancer Res 60 2840 2844 10850425 1:CAS:528: DC%2BD3cXjvFOlsb8%3D (Pubitemid 30395803)
12. EM Langenfeld SE Caivano F Abou-Nukta, et al. 2003 The mature bone morphogenetic protein-2 is aberrantly expressed in non-small cell lung carcinomas and stimulates tumor growth of A549 cells Carcinogenesis 24 1445 1454 12819188 10.1093/carcin/bgg100 1:CAS:528:DC%2BD3sXnt1Kjsr0%3D (Pubitemid 37160834)
13. D Laurent F Jean-Jacques B Sabine 2009 Emerging role of bone morphogenetic proteins in angiogenesis Cytokine & Growth Factor Reviews 20 203 212 10.1016/j.cytogfr.2009.05.001
14. JZ Li H Li T Sasaki, et al. 2003 Osteogenic potential of five different recombinant human bone morphogenetic protein adenoviral vectors in the rat Gene Ther 10 1735 1743 12939640 10.1038/sj.gt.3302075 1:CAS:528:DC%2BD3sXms1Crtbk%3D (Pubitemid 37121045)
15. YE Lin SM Bokobza WG Jiang 2009 Bone morphogenetic proteins in development and progression of breast cancer and therapeutic potential International Journal of Molecular Medicine 24 591 597 1:CAS:528: DC%2BD1MXksF2ks7s%3D
16. JW Lowery MP Caestecker 2010 BMP signaling in vascular development and disease Cytokine &Growth factor reviews 21 287 298 10.1016/j.cytogfr.2010. 06.001 1:CAS:528:DC%2BC3cXhtFGjsbfP
17. MK Majumdar E Wang EA Morris, et al. 2001 BMP-2 and BMP-9 promotes chondrogenic differentiation of human multipotential mesenchymal cells and overcomes the inhibitory effect of IL-1 J Cell Physiol 189 275 284 11748585 10.1002/jcp.10025 1:CAS:528:DC%2BD3MXotFGqsbY%3D (Pubitemid 33063295)
18. RE Ploemacher LJ Engels AE Mayer, et al. 1999 Bone mophogenetic protein 9 is a potent synergistic factor for murine hemopoietic progenitor cell generation and colony formation in serum-free cultures Leukemia 13 428 437 10086734 10.1038/sj.leu.2401363 1:CAS:528:DyaK1MXitFamtrg%3D (Pubitemid 29108082)
19. A Singh RJ Morris 2010 The Yin and Yang of bone morphogenetic proteins in cancer Cytokine &Growth factor reviews 21 299 313 10.1016/j.cytogfr.2010. 06.003 1:CAS:528:DC%2BC3cXhtFGjsbfI
20. JJ Song AJ Celeste FM Kong, et al. 1995 Bone mophogenetic protein -9 binds to liver cells and stimulates proliferation Endocrinology 136 4293 4297 7664647 10.1210/en.136.10.4293 1:CAS:528:DyaK2MXot1Wmurc%3D
21. DO Wagner C Sieber R Bhushan, et al. 2010 BMPs: From Bone to Body Morphogenetic Proteins Science Signaling 3 1 6
22. L Ye K Howard WG Jiang 2008 Bone Morphogenetic Protein-9 Induces Apoptosis in Prostate Cancer Cells, the Role of Prostate Apoptosis Response-4 Mol Cancer Res 10 1594 1606 10.1158/1541-7786.MCR-08-0171