Inhibition of ubiquitin proteasome system enzymes for anticancer therapy

Annual Reports in Medicinal Chemistry

Volumn 48, Issue , 2013, Pages 205-225

  Wustrow, David ^a   Zhou, Han Jie ^a   Rolfe, Mark ^a  

^a Cleave Biosciences   (United States)

Author keywords

26S Proteasome; Bortezomib; Carfilzomib; Imides; MDM2; MLN4924; MLN9708; P97 VCP; Ubiquitin ligases; Lactones

Indexed keywords

ANTINEOPLASTIC AGENT; BORTEZOMIB; CARFILZOMIB; CASPASE 3; CASPASE 8; CASPASE 9; CC 0651; DELANZOMIB; DEXAMETHASONE; FR 259625; HISTONE DEACETYLASE INHIBITOR; IXAZOMIB; IXAZOMIB CITRATE; LACTACYSTIN BETA LACTONE; LENALIDOMIDE; ML 240; NUTLIN 3; OPROZOMIB; PEVONEDISTAT; POMALIDOMIDE; PR 047; PROTEIN MDM2; PROTEIN P53; PYZD 4409; RG 7112; RO 5503781; SALINOSPORAMIDE A; SERDEMETAN; STRESS ACTIVATED PROTEIN KINASE; THALIDOMIDE; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VASCULOTROPIN;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CANCER THERAPY; CELL PROLIFERATION; CELL SURVIVAL; CYTOTOXICITY; DNA REPAIR; ENZYME INHIBITION; HUMAN; HYDROLYSIS; MULTIPLE MYELOMA; NONHUMAN; PERIPHERAL NEUROPATHY; PHASE 1 CLINICAL TRIAL (TOPIC); PHASE 2 CLINICAL TRIAL (TOPIC); PROTEIN INTERACTION; STRUCTURE ACTIVITY RELATION; UBIQUITIN PROTEASOME INHIBITION; X RAY CRYSTALLOGRAPHY;

EID: 84884147586     PISSN: 00657743     EISSN: None     Source Type: Book Series    
DOI: 10.1016/B978-0-12-417150-3.00014-4     Document Type: Chapter

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