메뉴 건너뛰기




Volumn 272, Issue 2, 2013, Pages 414-422

EPAC expression and function in cardiac fibroblasts and myofibroblasts

Author keywords

Adhesion; Cardiac fibroblast and myofibroblast; Collagen; EPAC 1; Migration; TGF beta1

Indexed keywords

ANTIPORTER; COLLAGEN GEL; EPAC 1 PROTEIN; FIBRONECTIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE B; SMAD PROTEIN; SMAD3 PROTEIN; SYNAPTOPHYSIN; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

EID: 84884136392     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2013.06.022     Document Type: Article
Times cited : (17)

References (35)
  • 2
    • 33751241720 scopus 로고    scopus 로고
    • EPAC proteins: multi-purpose cAMP targets
    • Bos J. EPAC proteins: multi-purpose cAMP targets. Trends Biochem. Sci. 2006, 31:680-686.
    • (2006) Trends Biochem. Sci. , vol.31 , pp. 680-686
    • Bos, J.1
  • 6
    • 0142104985 scopus 로고    scopus 로고
    • Smad dependent and Smad independent pathways in transforming growth factor family signal
    • Derynck R., Zhang Y. Smad dependent and Smad independent pathways in transforming growth factor family signal. Nature 2003, 425:577-584.
    • (2003) Nature , vol.425 , pp. 577-584
    • Derynck, R.1    Zhang, Y.2
  • 7
    • 0347358991 scopus 로고    scopus 로고
    • IGF-1 modulation of rat cardiac fibroblast behavior and gene expression is age-dependent
    • Diaz-Araya G., Borg T., Lavandero S., Loftis M., Carver W. IGF-1 modulation of rat cardiac fibroblast behavior and gene expression is age-dependent. Cell Commun. Adhes. 2003, 10:155-165.
    • (2003) Cell Commun. Adhes. , vol.10 , pp. 155-165
    • Diaz-Araya, G.1    Borg, T.2    Lavandero, S.3    Loftis, M.4    Carver, W.5
  • 8
    • 0037899249 scopus 로고    scopus 로고
    • The myofibroblast in wound healing and fibrocontractive diseases
    • Gabbiani G. The myofibroblast in wound healing and fibrocontractive diseases. J. Pathol. 2003, 200:500-503.
    • (2003) J. Pathol. , vol.200 , pp. 500-503
    • Gabbiani, G.1
  • 9
    • 77949538387 scopus 로고    scopus 로고
    • EPAC: defining a new mechanism for cAMP action
    • Gloerich M., Bos J. EPAC: defining a new mechanism for cAMP action. Annu. Rev. Pharmacol. Toxicol. 2010, 50:355-375.
    • (2010) Annu. Rev. Pharmacol. Toxicol. , vol.50 , pp. 355-375
    • Gloerich, M.1    Bos, J.2
  • 10
    • 33644948094 scopus 로고    scopus 로고
    • Master and servants of the force: the role of matrix adhesions in myofibroblast force perception and transmission
    • Hinz B. Master and servants of the force: the role of matrix adhesions in myofibroblast force perception and transmission. Eur. J. Cell Biol. 2006, 85:175-181.
    • (2006) Eur. J. Cell Biol. , vol.85 , pp. 175-181
    • Hinz, B.1
  • 11
    • 53449089229 scopus 로고    scopus 로고
    • Prostaglandin E2 inhibits specific lung fibroblast function via selective actions of PKA and EPAC-1
    • Huang S., Wettlaufer S., Chung J., Peters-Golden M. Prostaglandin E2 inhibits specific lung fibroblast function via selective actions of PKA and EPAC-1. Am. J. Respir. Cell Mol. Biol. 2008, 39(4):482-489.
    • (2008) Am. J. Respir. Cell Mol. Biol. , vol.39 , Issue.4 , pp. 482-489
    • Huang, S.1    Wettlaufer, S.2    Chung, J.3    Peters-Golden, M.4
  • 12
    • 24644476507 scopus 로고    scopus 로고
    • Crosstalk mechanisms between the mitogen-activated protein kinase pathways and Smad signaling downstream of TGF-β: implications for carcinogenesis
    • Javelaud D., Mauviel A. Crosstalk mechanisms between the mitogen-activated protein kinase pathways and Smad signaling downstream of TGF-β: implications for carcinogenesis. Oncogene 2005, 24:5742-5750.
    • (2005) Oncogene , vol.24 , pp. 5742-5750
    • Javelaud, D.1    Mauviel, A.2
  • 13
    • 34047182621 scopus 로고    scopus 로고
    • TGF-β cardiac fibroblasts and their fibrotic response
    • Leask A. TGF-β cardiac fibroblasts and their fibrotic response. Cardiovasc. Res. 2007, 74:207-212.
    • (2007) Cardiovasc. Res. , vol.74 , pp. 207-212
    • Leask, A.1
  • 14
    • 41149122223 scopus 로고    scopus 로고
    • Atrial natriuretic peptide inhibits transforming growth factor β induced Smad signaling and myofibroblast transformation in mouse cardiac fibroblasts
    • Li P., Wang D., Lucas J., Oparil S., Xing D., Cao X., Novak L., Renfrow M., Chen Y. Atrial natriuretic peptide inhibits transforming growth factor β induced Smad signaling and myofibroblast transformation in mouse cardiac fibroblasts. Circ. Res. 2008, 102:185-192.
    • (2008) Circ. Res. , vol.102 , pp. 185-192
    • Li, P.1    Wang, D.2    Lucas, J.3    Oparil, S.4    Xing, D.5    Cao, X.6    Novak, L.7    Renfrow, M.8    Chen, Y.9
  • 15
    • 84863230879 scopus 로고    scopus 로고
    • LPS disrupts the directional persistence of alveolar myofibroblast migration through EGF receptor
    • Li H., Yuan X., Tang J., Zhang Y. LPS disrupts the directional persistence of alveolar myofibroblast migration through EGF receptor. Am. J. Physiol. Lung Cell. Mol. Physiol. 2012, 302:569-570.
    • (2012) Am. J. Physiol. Lung Cell. Mol. Physiol. , vol.302 , pp. 569-570
    • Li, H.1    Yuan, X.2    Tang, J.3    Zhang, Y.4
  • 16
    • 0037813105 scopus 로고    scopus 로고
    • Transforming growth factor β1 mediated gel contraction by cardiac fibroblasts
    • Lijnen P., Petrov V., Fagard R. Transforming growth factor β1 mediated gel contraction by cardiac fibroblasts. J. Renin Angiotensin Aldosterone Syst. 2003, 4:113-117.
    • (2003) J. Renin Angiotensin Aldosterone Syst. , vol.4 , pp. 113-117
    • Lijnen, P.1    Petrov, V.2    Fagard, R.3
  • 17
    • 33751104222 scopus 로고    scopus 로고
    • CAMP inhibits transforming growth factor-β-stimulated collagen synthesis via inhibition of extracellular signal-regulated kinase 1/2 and Smad signaling in cardiac fibroblasts
    • Liu X., Sun Q., Hassid A., Ostrom R. cAMP inhibits transforming growth factor-β-stimulated collagen synthesis via inhibition of extracellular signal-regulated kinase 1/2 and Smad signaling in cardiac fibroblasts. Mol. Pharmacol. 2006, 70:1992-2003.
    • (2006) Mol. Pharmacol. , vol.70 , pp. 1992-2003
    • Liu, X.1    Sun, Q.2    Hassid, A.3    Ostrom, R.4
  • 18
    • 34250376057 scopus 로고    scopus 로고
    • FAK is required for TGF-induced JNK phosphorylation in fibroblasts: implications for acquisition of a matrix-remodeling phenotype
    • Liu S., Shi-Wen X., Kennedy L., Pala D., Chen Y., Eastwood M., Carter D., Black C., Abraham D., Leask A. FAK is required for TGF-induced JNK phosphorylation in fibroblasts: implications for acquisition of a matrix-remodeling phenotype. Mol. Biol. Cell 2007, 18:2169-2178.
    • (2007) Mol. Biol. Cell , vol.18 , pp. 2169-2178
    • Liu, S.1    Shi-Wen, X.2    Kennedy, L.3    Pala, D.4    Chen, Y.5    Eastwood, M.6    Carter, D.7    Black, C.8    Abraham, D.9    Leask, A.10
  • 19
    • 48749131442 scopus 로고    scopus 로고
    • Kr channels and cAMP-PKA pathway modulate TGF-β 1 induced migration of rat vascular myofibroblasts
    • Liu Y., Ye W., Zeng X., Ren W., Zhang Y. Kr channels and cAMP-PKA pathway modulate TGF-β 1 induced migration of rat vascular myofibroblasts. J. Cell. Physiol. 2008, 216:835-843.
    • (2008) J. Cell. Physiol. , vol.216 , pp. 835-843
    • Liu, Y.1    Ye, W.2    Zeng, X.3    Ren, W.4    Zhang, Y.5
  • 20
    • 42249085404 scopus 로고    scopus 로고
    • CAMP-induced EPAC-Rap activation inhibits epithelial cell migration by modulating focal adhesion and leading edge dynamics
    • Lyle K., Raaijmakers J., Bruinsma W., Bos J., Rooij J. cAMP-induced EPAC-Rap activation inhibits epithelial cell migration by modulating focal adhesion and leading edge dynamics. Cell. Signal. 2008, 20:1104-1116.
    • (2008) Cell. Signal. , vol.20 , pp. 1104-1116
    • Lyle, K.1    Raaijmakers, J.2    Bruinsma, W.3    Bos, J.4    Rooij, J.5
  • 21
    • 0034574298 scopus 로고    scopus 로고
    • How cells read TGF-β signals
    • Massagué J. How cells read TGF-β signals. Nat. Rev. Mol. Cell Biol. 2009, 1:169-178.
    • (2009) Nat. Rev. Mol. Cell Biol. , vol.1 , pp. 169-178
    • Massagué, J.1
  • 22
    • 33847676783 scopus 로고    scopus 로고
    • Fibroblasts and myofibroblasts: their source, function and role in disease
    • Mc Anulty R. Fibroblasts and myofibroblasts: their source, function and role in disease. Int. J. Biochem. Cell Biol. 2006, 39:666-667.
    • (2006) Int. J. Biochem. Cell Biol. , vol.39 , pp. 666-667
    • Mc Anulty, R.1
  • 23
    • 0035988134 scopus 로고    scopus 로고
    • Influence of isoproterenol on the expression of angiotensin I-converting enzyme in lung, left ventricle and plasma during the development and regression of myocardial hypertrophy and fibrosis
    • Ocaranza M., Díaz Araya G., Chiong M., Muñoz D., Riveros J., Ebensperger R., Sabat S., Irarrázabal P., Jalil J., Lavandero S. Influence of isoproterenol on the expression of angiotensin I-converting enzyme in lung, left ventricle and plasma during the development and regression of myocardial hypertrophy and fibrosis. J. Cardiovasc. Pharmacol. 2002, 40:246-254.
    • (2002) J. Cardiovasc. Pharmacol. , vol.40 , pp. 246-254
    • Ocaranza, M.1    Díaz Araya, G.2    Chiong, M.3    Muñoz, D.4    Riveros, J.5    Ebensperger, R.6    Sabat, S.7    Irarrázabal, P.8    Jalil, J.9    Lavandero, S.10
  • 24
    • 67249152096 scopus 로고    scopus 로고
    • Cardiac fibroblasts: at the heart of myocardial remodelling
    • Porter K., Turner N. Cardiac fibroblasts: at the heart of myocardial remodelling. Pharmacol. Ther. 2009, 123:255-278.
    • (2009) Pharmacol. Ther. , vol.123 , pp. 255-278
    • Porter, K.1    Turner, N.2
  • 25
    • 23044513107 scopus 로고    scopus 로고
    • β2-adrenergic receptor activation delays dermal fibroblast-mediated contraction of collagen gels via a cAMP-dependent mechanism
    • Pullar C., Isserof F. β2-adrenergic receptor activation delays dermal fibroblast-mediated contraction of collagen gels via a cAMP-dependent mechanism. Wound Repair Regen. 2005, 13:405-411.
    • (2005) Wound Repair Regen. , vol.13 , pp. 405-411
    • Pullar, C.1    Isserof, F.2
  • 26
    • 0037450725 scopus 로고    scopus 로고
    • CAMP induces integrin-mediated cell adhesion through EPAC and Rap 1 upon stimulation of the β2 adrenergic receptor
    • Rangarajan S., Enserink J., Kuiperij H., Rooij J., Price L., Schwede F., Bos J. cAMP induces integrin-mediated cell adhesion through EPAC and Rap 1 upon stimulation of the β2 adrenergic receptor. J. Cell Biol. 2003, 160:487-493.
    • (2003) J. Cell Biol. , vol.160 , pp. 487-493
    • Rangarajan, S.1    Enserink, J.2    Kuiperij, H.3    Rooij, J.4    Price, L.5    Schwede, F.6    Bos, J.7
  • 27
    • 24944551371 scopus 로고    scopus 로고
    • Animal models of cardiac fibrosis
    • Sun Y., Weber K. Animal models of cardiac fibrosis. Methods Mol. Med. 2005, 117:273-290.
    • (2005) Methods Mol. Med. , vol.117 , pp. 273-290
    • Sun, Y.1    Weber, K.2
  • 28
    • 0036277026 scopus 로고    scopus 로고
    • Myofibroblasts and mechanoregulation of connective tissue remodelling
    • Tomasek J., Gabbiani G., Hinz C., Chaponnier R. Myofibroblasts and mechanoregulation of connective tissue remodelling. Nat. Rev. Mol. 2002, 3:349-363.
    • (2002) Nat. Rev. Mol. , vol.3 , pp. 349-363
    • Tomasek, J.1    Gabbiani, G.2    Hinz, C.3    Chaponnier, R.4
  • 32
    • 79956352333 scopus 로고    scopus 로고
    • Induction of cardiac fibroblast lysyl oxidase by TGF-β1 requires PI3K/Akt, Smad3, and MAPK signaling
    • Voloshenyuk T., Landesman E., Khoutorova E., Hart A., Gardner J. Induction of cardiac fibroblast lysyl oxidase by TGF-β1 requires PI3K/Akt, Smad3, and MAPK signaling. Cytokine 2011, 55:90-97.
    • (2011) Cytokine , vol.55 , pp. 90-97
    • Voloshenyuk, T.1    Landesman, E.2    Khoutorova, E.3    Hart, A.4    Gardner, J.5
  • 33
    • 0034585189 scopus 로고    scopus 로고
    • Recruitable ACE and tissue repair in the infarcted heart
    • Weber K., Sun Y. Recruitable ACE and tissue repair in the infarcted heart. J. Renin Angiotensin Aldosterone Syst. 2000, 14:295-303.
    • (2000) J. Renin Angiotensin Aldosterone Syst. , vol.14 , pp. 295-303
    • Weber, K.1    Sun, Y.2
  • 34
    • 44049098742 scopus 로고    scopus 로고
    • The cyclic AMP effector EPAC integrates pro- and anti-fibrotic signals
    • Yokoyama U., Patel H., Lai N., Aroonsakool N., Roth D., Insel P. The cyclic AMP effector EPAC integrates pro- and anti-fibrotic signals. PNAS 2008, 105:6386-6391.
    • (2008) PNAS , vol.105 , pp. 6386-6391
    • Yokoyama, U.1    Patel, H.2    Lai, N.3    Aroonsakool, N.4    Roth, D.5    Insel, P.6
  • 35
    • 58149213801 scopus 로고    scopus 로고
    • Non Smad pathways in TGF-β signaling
    • Zhang Y. Non Smad pathways in TGF-β signaling. Cell Res. 2009, 19:128-139.
    • (2009) Cell Res. , vol.19 , pp. 128-139
    • Zhang, Y.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.