-
1
-
-
33646799069
-
Global and regional burden of disease and risk factors, 2001: systematic analysis of population health data
-
Lopez AD, Mathers CD, Ezzati M, Jamison DT, Murray CJ Global and regional burden of disease and risk factors, 2001: systematic analysis of population health data. Lancet 2006, 367(9524):1747-1757.
-
(2006)
Lancet
, vol.367
, Issue.9524
, pp. 1747-1757
-
-
Lopez, A.D.1
Mathers, C.D.2
Ezzati, M.3
Jamison, D.T.4
Murray, C.J.5
-
2
-
-
15844390942
-
Pathogenesis and management of pain in osteoarthritis
-
Dieppe PA, Lohmander LS Pathogenesis and management of pain in osteoarthritis. Lancet 2005, 365:965-973.
-
(2005)
Lancet
, vol.365
, pp. 965-973
-
-
Dieppe, P.A.1
Lohmander, L.S.2
-
3
-
-
84883929312
-
-
<> [accessed 16.08.11].
-
<> [accessed 16.08.11]. http://www.njrcentre.org.uk/njrcentre/Patients/Jointreplacementstatistic s/tabid/99/Default.aspx.
-
-
-
-
4
-
-
67649472540
-
Cost-effectiveness of total knee arthroplasty in the United States: patient risk and hospital volume
-
Losina E, Walensky RP, Kessler CL, et al. Cost-effectiveness of total knee arthroplasty in the United States: patient risk and hospital volume. Arch Intern Med 2009, 169(12):1113-1121.
-
(2009)
Arch Intern Med
, vol.169
, Issue.12
, pp. 1113-1121
-
-
Losina, E.1
Walensky, R.P.2
Kessler, C.L.3
-
5
-
-
0008184427
-
Epidemiology of osteoarthritis
-
Lippincott Williams & Wilkins, Philadelphia, R.W. Moskowitz, R.D. Altman, M.C. Hochberg, J.A. Buckwalter, V.M. Goldberg (Eds.)
-
Sharma L, Kapoor D Epidemiology of osteoarthritis. Osteoarthritis: diagnosis and medical/surgical management. 2007, 3-26. Lippincott Williams & Wilkins, Philadelphia. 4th ed. R.W. Moskowitz, R.D. Altman, M.C. Hochberg, J.A. Buckwalter, V.M. Goldberg (Eds.).
-
(2007)
Osteoarthritis: diagnosis and medical/surgical management.
, pp. 3-26
-
-
Sharma, L.1
Kapoor, D.2
-
6
-
-
0028824690
-
Atlas of individual radiographic features in osteoarthritis
-
Altman RD, Hochberg M, Murphy WA, Wolfe F, Lequesne M Atlas of individual radiographic features in osteoarthritis. Osteoarthritis Cartilage 1995, 3(Suppl. A):3-70.
-
(1995)
Osteoarthritis Cartilage
, vol.3
, Issue.SUPPL. A
, pp. 3-70
-
-
Altman, R.D.1
Hochberg, M.2
Murphy, W.A.3
Wolfe, F.4
Lequesne, M.5
-
7
-
-
65249154819
-
Defining incident radiographic hip osteoarthritis for epidemiologic studies in women
-
Arden NK, Lane NE, Parimi N, Javaid KM, Lui LY, Hochberg MC, et al. Defining incident radiographic hip osteoarthritis for epidemiologic studies in women. Arthritis Rheum 2009, 60(4):1052-1059.
-
(2009)
Arthritis Rheum
, vol.60
, Issue.4
, pp. 1052-1059
-
-
Arden, N.K.1
Lane, N.E.2
Parimi, N.3
Javaid, K.M.4
Lui, L.Y.5
Hochberg, M.C.6
-
8
-
-
84881264653
-
All cause and disease specific mortality in patients with knee or hip osteoarthritis: population based cohort study
-
Nüesch E, Dieppe P, Reichenbach S, Williams S, Iff S, Jüni P All cause and disease specific mortality in patients with knee or hip osteoarthritis: population based cohort study. Br Med J. 2011, 342:1165.
-
(2011)
Br Med J.
, vol.342
, pp. 1165
-
-
Nüesch, E.1
Dieppe, P.2
Reichenbach, S.3
Williams, S.4
Iff, S.5
Jüni, P.6
-
9
-
-
73449123799
-
The economic burden of osteoarthritis
-
Bitton R The economic burden of osteoarthritis. Am J Manag Care 2009, 15(8 Suppl):S230-S235.
-
(2009)
Am J Manag Care
, vol.15
, Issue.8 SUPPL
-
-
Bitton, R.1
-
10
-
-
73249153284
-
Insurer and out-of-pocket costs of osteoarthritis in the US: evidence from national survey data
-
Kotlarz H, Gunnarsson CL, Fang H, Rizzo JA Insurer and out-of-pocket costs of osteoarthritis in the US: evidence from national survey data. Arthritis Rheum 2009, 60(12):3546-3553.
-
(2009)
Arthritis Rheum
, vol.60
, Issue.12
, pp. 3546-3553
-
-
Kotlarz, H.1
Gunnarsson, C.L.2
Fang, H.3
Rizzo, J.A.4
-
11
-
-
80955180983
-
Nottingham knee osteoarthritis risk prediction models
-
Zhang W, McWilliams DF, Ingham SL, et al. Nottingham knee osteoarthritis risk prediction models. Ann Rheum Dis 2011, 70(9):1599-1604.
-
(2011)
Ann Rheum Dis
, vol.70
, Issue.9
, pp. 1599-1604
-
-
Zhang, W.1
McWilliams, D.F.2
Ingham, S.L.3
-
12
-
-
34548565635
-
Lessons from genetic forms of osteoarthritis for the pathogenesis of the disease
-
Li Y, Xu L, Olsen BR Lessons from genetic forms of osteoarthritis for the pathogenesis of the disease. Osteoarthritis Cartilage 2007, 15(10):1101-1105.
-
(2007)
Osteoarthritis Cartilage
, vol.15
, Issue.10
, pp. 1101-1105
-
-
Li, Y.1
Xu, L.2
Olsen, B.R.3
-
14
-
-
48349091422
-
The contribution of genes to osteoarthritis
-
Valdes AM, Spector TD The contribution of genes to osteoarthritis. Rheum Dis Clin North Am 2008, 34(3):581-603.
-
(2008)
Rheum Dis Clin North Am
, vol.34
, Issue.3
, pp. 581-603
-
-
Valdes, A.M.1
Spector, T.D.2
-
15
-
-
4644367208
-
Genetic mechanisms of knee osteoarthritis: a population based case-control study
-
Jones G, Ding C, Scott F, Cicuttini F Genetic mechanisms of knee osteoarthritis: a population based case-control study. Ann Rheum Dis 2004, 63(10):1255-1259.
-
(2004)
Ann Rheum Dis
, vol.63
, Issue.10
, pp. 1255-1259
-
-
Jones, G.1
Ding, C.2
Scott, F.3
Cicuttini, F.4
-
16
-
-
33846401119
-
Genetic influence on the progression of radiographic knee osteoarthritis: a longitudinal twin study
-
Zhai G, Hart DJ, Kato BS, MacGregor A, Spector TD Genetic influence on the progression of radiographic knee osteoarthritis: a longitudinal twin study. Osteoarthritis Cartilage 2007, 15(2):222-225.
-
(2007)
Osteoarthritis Cartilage
, vol.15
, Issue.2
, pp. 222-225
-
-
Zhai, G.1
Hart, D.J.2
Kato, B.S.3
MacGregor, A.4
Spector, T.D.5
-
18
-
-
0025019555
-
Linkage strategies for genetically complex traits. I. Multilocus models
-
Risch N Linkage strategies for genetically complex traits. I. Multilocus models. Am J Hum Genet 1990, 46:222-228.
-
(1990)
Am J Hum Genet
, vol.46
, pp. 222-228
-
-
Risch, N.1
-
19
-
-
78650977864
-
Genetic epidemiology of hip and knee osteoarthritis
-
Valdes AM, Spector TD Genetic epidemiology of hip and knee osteoarthritis. Nat Rev Rheumatol 2011, 7(1):23-32.
-
(2011)
Nat Rev Rheumatol
, vol.7
, Issue.1
, pp. 23-32
-
-
Valdes, A.M.1
Spector, T.D.2
-
20
-
-
79952637781
-
Hypertrophic differentiation of chondrocytes in osteoarthritis: the developmental aspect of degenerative joint disorders
-
Dreier R Hypertrophic differentiation of chondrocytes in osteoarthritis: the developmental aspect of degenerative joint disorders. Arthritis Res Ther 2010, 12(5):216.
-
(2010)
Arthritis Res Ther
, vol.12
, Issue.5
, pp. 216
-
-
Dreier, R.1
-
21
-
-
79955042501
-
Nosology and classification of genetic skeletal disorders: 2010 revision
-
Warman ML, Cormier-Daire V, Hall C, et al. Nosology and classification of genetic skeletal disorders: 2010 revision. Am J Med Genet Part A 2011, 155:943-968.
-
(2011)
Am J Med Genet Part A
, vol.155
, pp. 943-968
-
-
Warman, M.L.1
Cormier-Daire, V.2
Hall, C.3
-
22
-
-
0015109836
-
Osteochondritis dissecans of the knee: a clinical survey
-
Aichroth P Osteochondritis dissecans of the knee: a clinical survey. J Bone Joint Surg Br 1971, 53:440-447.
-
(1971)
J Bone Joint Surg Br
, vol.53
, pp. 440-447
-
-
Aichroth, P.1
-
23
-
-
0017050060
-
The incidence of osteochondritis dissecans in the condyles of the femur
-
Linden B The incidence of osteochondritis dissecans in the condyles of the femur. Acta Orthop Scand 1976, 47:664-667.
-
(1976)
Acta Orthop Scand
, vol.47
, pp. 664-667
-
-
Linden, B.1
-
24
-
-
76049108551
-
A missense mutation in the aggrecan C-type lectin domain disrupts extracellular matrix interactions and causes dominant familial osteochondritis dissecans
-
Stattin EL, Wiklund F, Lindblom K, et al. A missense mutation in the aggrecan C-type lectin domain disrupts extracellular matrix interactions and causes dominant familial osteochondritis dissecans. Am J Hum Genet 2010, 86:126-137.
-
(2010)
Am J Hum Genet
, vol.86
, pp. 126-137
-
-
Stattin, E.L.1
Wiklund, F.2
Lindblom, K.3
-
25
-
-
0029035708
-
Mutations in exon 17B of cartilage oligomeric matrix protein (COMP) cause pseudoachondroplasia
-
Hecht JT, Nelson LD, Crowder E, et al. Mutations in exon 17B of cartilage oligomeric matrix protein (COMP) cause pseudoachondroplasia. Nat Genet 1995, 10:325-329.
-
(1995)
Nat Genet
, vol.10
, pp. 325-329
-
-
Hecht, J.T.1
Nelson, L.D.2
Crowder, E.3
-
26
-
-
2342577420
-
Spondyloepimetaphyseal dysplasia (SEMD) matrilin 3 type: homozygote matrilin 3 mutation in a novel form of SEM
-
Borochowitz ZU, Scheffer D, Adir V, Dagoneau N, Munnich A, Cormier-Daire V Spondyloepimetaphyseal dysplasia (SEMD) matrilin 3 type: homozygote matrilin 3 mutation in a novel form of SEM. J Med Genet 2004, 41:366-372.
-
(2004)
J Med Genet
, vol.41
, pp. 366-372
-
-
Borochowitz, Z.U.1
Scheffer, D.2
Adir, V.3
Dagoneau, N.4
Munnich, A.5
Cormier-Daire, V.6
-
27
-
-
0141746302
-
Autosomal recessive multiple epiphyseal dysplasia with homozygosity for C653S in the DTDST gene: double-layer patella as a reliable sign
-
Mäkitie O, Savarirayan R, Bonafé L, Robertson S, Susic M, Superti-Furga A, et al. Autosomal recessive multiple epiphyseal dysplasia with homozygosity for C653S in the DTDST gene: double-layer patella as a reliable sign. Am J Med Genet A 2003, 122A(3):187-192.
-
(2003)
Am J Med Genet A
, vol.122 A
, Issue.3
, pp. 187-192
-
-
Mäkitie, O.1
Savarirayan, R.2
Bonafé, L.3
Robertson, S.4
Susic, M.5
Superti-Furga, A.6
-
28
-
-
0034933884
-
Mutations in the region encoding the von Willebrand factor A domain of matrilin-3 are associated with multiple epiphyseal dysplasia
-
Chapman KL, Mortier GR, Chapman K, Loughlin J, Grant ME, Briggs MD Mutations in the region encoding the von Willebrand factor A domain of matrilin-3 are associated with multiple epiphyseal dysplasia. Nat Genet 2001, 28(4):393-396.
-
(2001)
Nat Genet
, vol.28
, Issue.4
, pp. 393-396
-
-
Chapman, K.L.1
Mortier, G.R.2
Chapman, K.3
Loughlin, J.4
Grant, M.E.5
Briggs, M.D.6
-
29
-
-
33746641679
-
Functional knockout of the matrilin-3 gene causes premature chondrocyte maturation to hypertrophy and increases bone mineral density and osteoarthritis
-
van der Weyden L, Wei L, Luo J, Yang X, Birk DE, Adams DJ, et al. Functional knockout of the matrilin-3 gene causes premature chondrocyte maturation to hypertrophy and increases bone mineral density and osteoarthritis. Am J Pathol 2006, 169(2):515-527.
-
(2006)
Am J Pathol
, vol.169
, Issue.2
, pp. 515-527
-
-
van der Weyden, L.1
Wei, L.2
Luo, J.3
Yang, X.4
Birk, D.E.5
Adams, D.J.6
-
30
-
-
65749116622
-
TRAPPC2L is a novel, highly conserved TRAPP-interacting protein
-
Scrivens PJ, Shahrzad N, Moores A, Morin A, Brunet S, Sacher M TRAPPC2L is a novel, highly conserved TRAPP-interacting protein. Traffic 2009, 10(6):724-736.
-
(2009)
Traffic
, vol.10
, Issue.6
, pp. 724-736
-
-
Scrivens, P.J.1
Shahrzad, N.2
Moores, A.3
Morin, A.4
Brunet, S.5
Sacher, M.6
-
31
-
-
77956286311
-
SEDLIN forms homodimers: characterisation of SEDLIN mutations and their interactions with transcription factors MBP1, PITX1 and SF1
-
Jeyabalan J, Nesbit MA, Galvanovskis J, Callaghan R, Rorsman P, Thakker RV SEDLIN forms homodimers: characterisation of SEDLIN mutations and their interactions with transcription factors MBP1, PITX1 and SF1. PLoS One 2010, 5(5):e10646.
-
(2010)
PLoS One
, vol.5
, Issue.5
-
-
Jeyabalan, J.1
Nesbit, M.A.2
Galvanovskis, J.3
Callaghan, R.4
Rorsman, P.5
Thakker, R.V.6
-
32
-
-
44349172432
-
Early-onset osteoarthritis due to otospondylomegaepiphyseal dysplasia in a family with a novel splicing mutation of the COL11A2 gene
-
Avcin T, Makitie O, Susic M, et al. Early-onset osteoarthritis due to otospondylomegaepiphyseal dysplasia in a family with a novel splicing mutation of the COL11A2 gene. J Rheumatol 2008, 35(5):920-926.
-
(2008)
J Rheumatol
, vol.35
, Issue.5
, pp. 920-926
-
-
Avcin, T.1
Makitie, O.2
Susic, M.3
-
33
-
-
19944429400
-
COL11A2 mutation associated with autosomal recessive Weissenbacher-Zweymuller syndrome: molecular and clinical overlap with otospondylomegaepiphyseal dysplasia (OSMED)
-
Harel T, Rabinowitz R, Hendler N, et al. COL11A2 mutation associated with autosomal recessive Weissenbacher-Zweymuller syndrome: molecular and clinical overlap with otospondylomegaepiphyseal dysplasia (OSMED). Am J Med Genet A 2005, 132A(1):33-35.
-
(2005)
Am J Med Genet A
, vol.132 A
, Issue.1
, pp. 33-35
-
-
Harel, T.1
Rabinowitz, R.2
Hendler, N.3
-
34
-
-
4644306883
-
A stop codon mutation in COL11A2 induces exon skipping and leads to non-ocular Stickler syndrome
-
Vuoristo MM, Pappas JG, Jansen V, Ala-Kokko L A stop codon mutation in COL11A2 induces exon skipping and leads to non-ocular Stickler syndrome. Am J Med Genet A 2004, 130A(2):160-164.
-
(2004)
Am J Med Genet A
, vol.130 A
, Issue.2
, pp. 160-164
-
-
Vuoristo, M.M.1
Pappas, J.G.2
Jansen, V.3
Ala-Kokko, L.4
-
35
-
-
34249705260
-
Missense and silent mutations in COL2A1 result in Stickler syndrome but via different molecular mechanisms
-
Richards AJ, Laidlaw M, Meredith SP, et al. Missense and silent mutations in COL2A1 result in Stickler syndrome but via different molecular mechanisms. Hum Mutat 2007, 28(6):639.
-
(2007)
Hum Mutat
, vol.28
, Issue.6
, pp. 639
-
-
Richards, A.J.1
Laidlaw, M.2
Meredith, S.P.3
-
36
-
-
33846809282
-
A report on 10 new patients with heterozygous mutations in the COL11A1 gene and a review of genotype-phenotype correlations in type XI collagenopathies
-
Majava M, Hoornaert KP, Bartholdi D, et al. A report on 10 new patients with heterozygous mutations in the COL11A1 gene and a review of genotype-phenotype correlations in type XI collagenopathies. Am J Med Genet A 2007, 143(3):258-264.
-
(2007)
Am J Med Genet A
, vol.143
, Issue.3
, pp. 258-264
-
-
Majava, M.1
Hoornaert, K.P.2
Bartholdi, D.3
-
37
-
-
0033365199
-
Splicing mutations of 54-bp exons in the COL11A1 gene cause Marshall syndrome, but other mutations cause overlapping Marshall/Stickler phenotypes
-
Annunen S, Körkkö J, Czarny M, et al. Splicing mutations of 54-bp exons in the COL11A1 gene cause Marshall syndrome, but other mutations cause overlapping Marshall/Stickler phenotypes. Am J Hum Genet 1999, 65(4):974-983.
-
(1999)
Am J Hum Genet
, vol.65
, Issue.4
, pp. 974-983
-
-
Annunen, S.1
Körkkö, J.2
Czarny, M.3
-
38
-
-
0032231735
-
Marshall syndrome and a defect at the COL11A1 locus
-
Shanske A, Bogdanow A, Shprintzen RJ, Marion RW Marshall syndrome and a defect at the COL11A1 locus. Am J Hum Genet 1998, 63(5):1558-1561.
-
(1998)
Am J Hum Genet
, vol.63
, Issue.5
, pp. 1558-1561
-
-
Shanske, A.1
Bogdanow, A.2
Shprintzen, R.J.3
Marion, R.W.4
-
39
-
-
0031949272
-
Marshall syndrome associated with a splicing defect at the COL11A1 locus
-
Griffith AJ, Sprunger LK, Sirko-Osadsa DA, Tiller GE, Meisler MH, Warman ML Marshall syndrome associated with a splicing defect at the COL11A1 locus. Am J Hum Genet 1998, 62(4):816-823.
-
(1998)
Am J Hum Genet
, vol.62
, Issue.4
, pp. 816-823
-
-
Griffith, A.J.1
Sprunger, L.K.2
Sirko-Osadsa, D.A.3
Tiller, G.E.4
Meisler, M.H.5
Warman, M.L.6
-
40
-
-
0030850795
-
Progressive pseudorheumatoid dysplasia: report of a family and review
-
el-Shanti HE, Omari HZ, Qubain HI Progressive pseudorheumatoid dysplasia: report of a family and review. J Med Genet 1997, 34(7):559-563.
-
(1997)
J Med Genet
, vol.34
, Issue.7
, pp. 559-563
-
-
el-Shanti, H.E.1
Omari, H.Z.2
Qubain, H.I.3
-
41
-
-
34548013963
-
Cellular and molecular responses in progressive pseudorheumatoid dysplasia articular cartilage associated with compound heterozygous WISP3 gene mutation
-
Zhou HD, Bu YH, Peng YQ, et al. Cellular and molecular responses in progressive pseudorheumatoid dysplasia articular cartilage associated with compound heterozygous WISP3 gene mutation. J Mol Med (Berl) 2007, 85(9):985-996.
-
(2007)
J Mol Med (Berl)
, vol.85
, Issue.9
, pp. 985-996
-
-
Zhou, H.D.1
Bu, Y.H.2
Peng, Y.Q.3
-
42
-
-
55849115677
-
Dyggve-Melchior-Clausen syndrome: chondrodysplasia resulting from defects in intracellular vesicle traffic
-
Osipovich AB, Jennings JL, Lin Q, Link AJ, Ruley HE Dyggve-Melchior-Clausen syndrome: chondrodysplasia resulting from defects in intracellular vesicle traffic. Proc Natl Acad Sci USA 2008, 105(42):16171-16176.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, Issue.42
, pp. 16171-16176
-
-
Osipovich, A.B.1
Jennings, J.L.2
Lin, Q.3
Link, A.J.4
Ruley, H.E.5
-
43
-
-
0442276482
-
Matrix remodeling during endochondral ossification
-
Ortega N, Behonick DJ, Werb Z Matrix remodeling during endochondral ossification. Trends Cell Biol 2004, 14(2):86-93.
-
(2004)
Trends Cell Biol
, vol.14
, Issue.2
, pp. 86-93
-
-
Ortega, N.1
Behonick, D.J.2
Werb, Z.3
-
44
-
-
23944438868
-
A mutation in the variable repeat region of the aggrecan gene (AGC1) causes a form of spondyloepiphyseal dysplasia associated with severe, premature osteoarthritis
-
Gleghorn L, Ramesar R, Beighton P, Wallis G A mutation in the variable repeat region of the aggrecan gene (AGC1) causes a form of spondyloepiphyseal dysplasia associated with severe, premature osteoarthritis. Am J Hum Genet 2005, 77(3):484-490.
-
(2005)
Am J Hum Genet
, vol.77
, Issue.3
, pp. 484-490
-
-
Gleghorn, L.1
Ramesar, R.2
Beighton, P.3
Wallis, G.4
-
45
-
-
3042750623
-
Loss of chondroitin 6-O-sulfotransferase-1 function results in severe human chondrodysplasia with progressive spinal involvement
-
Thiele H, Sakano M, Kitagawa H, Sugahara K, Rajab A, Höhne W, et al. Loss of chondroitin 6-O-sulfotransferase-1 function results in severe human chondrodysplasia with progressive spinal involvement. Proc Natl Acad Sci USA 2004, 101(27):10155-10160.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, Issue.27
, pp. 10155-10160
-
-
Thiele, H.1
Sakano, M.2
Kitagawa, H.3
Sugahara, K.4
Rajab, A.5
Höhne, W.6
-
46
-
-
0025295907
-
Hypotrichosis with spondylometaphyseal dysplasia in three generations: a new autosomal dominant syndrome
-
Whyte MP, Petersen DJ, McAlister WH Hypotrichosis with spondylometaphyseal dysplasia in three generations: a new autosomal dominant syndrome. Am J Hum Genet 1990, 36:288-291.
-
(1990)
Am J Hum Genet
, vol.36
, pp. 288-291
-
-
Whyte, M.P.1
Petersen, D.J.2
McAlister, W.H.3
-
47
-
-
0027433585
-
Spondyloepimetaphyseal dysplasia: clinical and radiologic investigation of a large kindred manifesting autosomal dominant inheritance, and a review of the literature
-
Patel AC, McAlister WH, Whyte MP Spondyloepimetaphyseal dysplasia: clinical and radiologic investigation of a large kindred manifesting autosomal dominant inheritance, and a review of the literature. Medicine (Baltimore) 1993, 72:326-342.
-
(1993)
Medicine (Baltimore)
, vol.72
, pp. 326-342
-
-
Patel, A.C.1
McAlister, W.H.2
Whyte, M.P.3
-
49
-
-
0029160584
-
Dominant mutations in the type II collagen gene, COL2A1, produce spondyloepimetaphyseal dysplasia, Strudwick type
-
Tiller GE, et al. Dominant mutations in the type II collagen gene, COL2A1, produce spondyloepimetaphyseal dysplasia, Strudwick type. Nat Genet 1995, 11:87-89.
-
(1995)
Nat Genet
, vol.11
, pp. 87-89
-
-
Tiller, G.E.1
-
50
-
-
17344364658
-
Mutations in orthologous genes in human spondyloepimetaphyseal dysplasia and the brachymorphic mouse
-
ul Haque MF, et al. Mutations in orthologous genes in human spondyloepimetaphyseal dysplasia and the brachymorphic mouse. Nat Genet 1998, 20:157-162.
-
(1998)
Nat Genet
, vol.20
, pp. 157-162
-
-
ul Haque, M.F.1
-
51
-
-
26444528459
-
MMP13 mutation causes spondyloepimetaphyseal dysplasia, Missouri type (SEMD MO)
-
Kennedy AM, Inada M, Krane SM, et al. MMP13 mutation causes spondyloepimetaphyseal dysplasia, Missouri type (SEMD MO). J Clin Invest 2005, 115(10):2832-2842.
-
(2005)
J Clin Invest
, vol.115
, Issue.10
, pp. 2832-2842
-
-
Kennedy, A.M.1
Inada, M.2
Krane, S.M.3
-
52
-
-
65849384082
-
The role of cartilage oligomeric matrix protein (COMP) in skeletal disease
-
Posey KL, Hecht JT The role of cartilage oligomeric matrix protein (COMP) in skeletal disease. Curr Drug Targets 2008, 9(10):869-877.
-
(2008)
Curr Drug Targets
, vol.9
, Issue.10
, pp. 869-877
-
-
Posey, K.L.1
Hecht, J.T.2
-
53
-
-
71449114734
-
Proteoglycans and more - from molecules to biology
-
Heinegård D Proteoglycans and more - from molecules to biology. Int J Exp Pathol 2009, 90(6):575-586.
-
(2009)
Int J Exp Pathol
, vol.90
, Issue.6
, pp. 575-586
-
-
Heinegård, D.1
-
54
-
-
0035165385
-
Postnatal expression in hyaline cartilage of constitutively active human collagenase-3 (MMP-13) induces osteoarthritis in mice
-
Neuhold LA, Killar L, Zhao W, Sung ML, Warner L, Kulik, et al. Postnatal expression in hyaline cartilage of constitutively active human collagenase-3 (MMP-13) induces osteoarthritis in mice. J Clin Invest 2001, 107:35-44.
-
(2001)
J Clin Invest
, vol.107
, pp. 35-44
-
-
Neuhold, L.A.1
Killar, L.2
Zhao, W.3
Sung, M.L.4
Warner, L.5
Kulik6
-
55
-
-
73249137617
-
Murine metalloproteinase 13-deficient mice are resistant to osteoarthritic cartilage erosion but not chondrocyte hypertrophy or osteophyte development
-
Little CB, Barai A, Burkhardt D, et al. Murine metalloproteinase 13-deficient mice are resistant to osteoarthritic cartilage erosion but not chondrocyte hypertrophy or osteophyte development. Arthritis Rheum 2009, 60:3723-3733.
-
(2009)
Arthritis Rheum
, vol.60
, pp. 3723-3733
-
-
Little, C.B.1
Barai, A.2
Burkhardt, D.3
-
56
-
-
78751703383
-
Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22
-
Evangelou E, Valdes AM, Kerkhof HJ, et al. Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22. Ann Rheum Dis 2011, 70(2):349-355.
-
(2011)
Ann Rheum Dis
, vol.70
, Issue.2
, pp. 349-355
-
-
Evangelou, E.1
Valdes, A.M.2
Kerkhof, H.J.3
-
57
-
-
34047103363
-
Functional polymorphism in the 5′ UTR of GDF5 is associated with susceptibility to osteoarthritis
-
Miyamoto Y, Mabuchi A, Shi D, et al. functional polymorphism in the 5′ UTR of GDF5 is associated with susceptibility to osteoarthritis. Nat Genet 2007, 39(4):529-533.
-
(2007)
Nat Genet
, vol.39
, Issue.4
, pp. 529-533
-
-
Miyamoto, Y.1
Mabuchi, A.2
Shi, D.3
-
58
-
-
48349105759
-
Common variants in DVWA on chromosome 3p24.3 are associated with susceptibility to knee osteoarthritis
-
Miyamoto Y, Shi D, Nakajima M, et al. Common variants in DVWA on chromosome 3p24.3 are associated with susceptibility to knee osteoarthritis. Nat Genet 2008, 40(8):994-998.
-
(2008)
Nat Genet
, vol.40
, Issue.8
, pp. 994-998
-
-
Miyamoto, Y.1
Shi, D.2
Nakajima, M.3
-
59
-
-
78149408549
-
New sequence variants in HLA class II/III region associated with susceptibility to knee osteoarthritis identified by genome-wide association study
-
Nakajima M, Takahashi A, Kou I, et al. New sequence variants in HLA class II/III region associated with susceptibility to knee osteoarthritis identified by genome-wide association study. PLoS One 2010, 18;5(3):e9723.
-
(2010)
PLoS One
, Issue.3
-
-
Nakajima, M.1
Takahashi, A.2
Kou, I.3
-
60
-
-
43049122786
-
A meta-analysis of European and Asian cohorts reveals a global role of a functional SNP in the 5′ UTR of GDF5 with osteoarthritis susceptibility
-
Chapman K, Takahashi A, Meulenbelt I, et al. A meta-analysis of European and Asian cohorts reveals a global role of a functional SNP in the 5′ UTR of GDF5 with osteoarthritis susceptibility. Hum Mol Genet 2008, 17(10):1497-1504.
-
(2008)
Hum Mol Genet
, vol.17
, Issue.10
, pp. 1497-1504
-
-
Chapman, K.1
Takahashi, A.2
Meulenbelt, I.3
-
61
-
-
78650988509
-
The GDF5 rs143383 polymorphism is associated with osteoarthritis of the knee with genome-wide statistical significance
-
Valdes AM, Evangelou E, Kerkhof HJ, et al. The GDF5 rs143383 polymorphism is associated with osteoarthritis of the knee with genome-wide statistical significance. Ann Rheum Dis 2011, 70:873-875.
-
(2011)
Ann Rheum Dis
, vol.70
, pp. 873-875
-
-
Valdes, A.M.1
Evangelou, E.2
Kerkhof, H.J.3
-
62
-
-
75749110202
-
A genome-wide association study identifies an osteoarthritis susceptibility locus on chromosome 7q22
-
Kerkhof HJ, Lories RJ, Meulenbelt I, et al. A genome-wide association study identifies an osteoarthritis susceptibility locus on chromosome 7q22. Arthritis Rheum 2010, 62:499-510.
-
(2010)
Arthritis Rheum
, vol.62
, pp. 499-510
-
-
Kerkhof, H.J.1
Lories, R.J.2
Meulenbelt, I.3
-
63
-
-
84884034721
-
A variant in MCF2L is associated with osteoarthritis.
-
Day-Williams AG, Southam L, Panoutsopoulou K, Rayner NW, Esko T, et al. A variant in MCF2L is associated with osteoarthritis. Am J Hum Genet [in press].
-
Am J Hum Genet [in press].
-
-
Day-Williams, A.G.1
Southam, L.2
Panoutsopoulou, K.3
Rayner, N.W.4
Esko, T.5
-
64
-
-
34547790324
-
Meta-analysis of association between the ASPN D-repeat and osteoarthritis
-
Nakamura T, Shi D, Tzetis M, Rodriguez-Lopez J, et al. Meta-analysis of association between the ASPN D-repeat and osteoarthritis. Hum Mol Genet 2007, 16(14):1676-1681.
-
(2007)
Hum Mol Genet
, vol.16
, Issue.14
, pp. 1676-1681
-
-
Nakamura, T.1
Shi, D.2
Tzetis, M.3
Rodriguez-Lopez, J.4
-
65
-
-
77955365705
-
Genetic variation in the SMAD3 gene is associated with hip and knee osteoarthritis
-
Valdes AM, Spector TD, Tamm A, et al. Genetic variation in the SMAD3 gene is associated with hip and knee osteoarthritis. Arthritis Rheum 2010, 62(8):2347-2352.
-
(2010)
Arthritis Rheum
, vol.62
, Issue.8
, pp. 2347-2352
-
-
Valdes, A.M.1
Spector, T.D.2
Tamm, A.3
-
66
-
-
44849087738
-
A functional SNP in EDG2 increases susceptibility to knee osteoarthritis in Japanese
-
Mototani H, Iida A, Nakajima M, et al. A functional SNP in EDG2 increases susceptibility to knee osteoarthritis in Japanese. Hum Mol Genet 2008, 17(12):1790-1797.
-
(2008)
Hum Mol Genet
, vol.17
, Issue.12
, pp. 1790-1797
-
-
Mototani, H.1
Iida, A.2
Nakajima, M.3
-
67
-
-
44849113821
-
Identification of DIO2 as a new susceptibility locus for symptomatic osteoarthritis
-
Meulenbelt I, Min JL, Bos S, Houwing-Duistermaat JJ, van der Wijk HJ, et al. Identification of DIO2 as a new susceptibility locus for symptomatic osteoarthritis. Hum Mol Genet 2008, 17(12):1867-1875.
-
(2008)
Hum Mol Genet
, vol.17
, Issue.12
, pp. 1867-1875
-
-
Meulenbelt, I.1
Min, J.L.2
Bos, S.3
Houwing-Duistermaat, J.J.4
van der Wijk, H.J.5
-
68
-
-
77951590246
-
Radiographic severity of knee osteoarthritis is conditional on interleukin 1 receptor antagonist gene variations
-
Attur M, Wang HY, Kraus VB, Bukowski JF, Aziz N, Krasnokutsky S, et al. Radiographic severity of knee osteoarthritis is conditional on interleukin 1 receptor antagonist gene variations. Ann Rheum Dis 2010, 69(5):856-861.
-
(2010)
Ann Rheum Dis
, vol.69
, Issue.5
, pp. 856-861
-
-
Attur, M.1
Wang, H.Y.2
Kraus, V.B.3
Bukowski, J.F.4
Aziz, N.5
Krasnokutsky, S.6
-
69
-
-
79951858462
-
Large-scale meta-analysis of interleukin-1 beta and interleukin-1 receptor antagonist polymorphisms on risk of radiographic hip and knee osteoarthritis and severity of knee osteoarthritis
-
Kerkhof HJ, Doherty M, Arden NK, et al. Large-scale meta-analysis of interleukin-1 beta and interleukin-1 receptor antagonist polymorphisms on risk of radiographic hip and knee osteoarthritis and severity of knee osteoarthritis. Osteoarthritis Cartilage 2011, 19(3):265-271.
-
(2011)
Osteoarthritis Cartilage
, vol.19
, Issue.3
, pp. 265-271
-
-
Kerkhof, H.J.1
Doherty, M.2
Arden, N.K.3
-
70
-
-
80051474349
-
The Ile585Val TRPV1 variant is involved in risk of painful knee osteoarthritis
-
Valdes AM, De Wilde G, Doherty SA, et al. The Ile585Val TRPV1 variant is involved in risk of painful knee osteoarthritis. Ann Rheum Dis 2011, 70(9):1556-1561.
-
(2011)
Ann Rheum Dis
, vol.70
, Issue.9
, pp. 1556-1561
-
-
Valdes, A.M.1
De Wilde, G.2
Doherty, S.A.3
-
71
-
-
58849145676
-
Finding genes underlying human disease
-
Stein CM, Elston RC Finding genes underlying human disease. Clin Genet. 2009, 75:101-106.
-
(2009)
Clin Genet.
, vol.75
, pp. 101-106
-
-
Stein, C.M.1
Elston, R.C.2
-
72
-
-
44449153906
-
Genome-wide association scan identifies a prostaglandin-endoperoxide synthase 2 variant involved in risk of knee osteoarthritis
-
Valdes AM, Loughlin J, Timms KM, et al. Genome-wide association scan identifies a prostaglandin-endoperoxide synthase 2 variant involved in risk of knee osteoarthritis. Am J Hum Genet 2008, 82(6):1231-1240.
-
(2008)
Am J Hum Genet
, vol.82
, Issue.6
, pp. 1231-1240
-
-
Valdes, A.M.1
Loughlin, J.2
Timms, K.M.3
-
73
-
-
72249115093
-
Association of the DVWA and GDF5 polymorphisms with osteoarthritis in UK populations
-
Valdes AM, Spector TD, Doherty S, Wheeler M, Hart DJ, Doherty M Association of the DVWA and GDF5 polymorphisms with osteoarthritis in UK populations. Ann Rheum Dis 2009, 68(12):1916-1920.
-
(2009)
Ann Rheum Dis
, vol.68
, Issue.12
, pp. 1916-1920
-
-
Valdes, A.M.1
Spector, T.D.2
Doherty, S.3
Wheeler, M.4
Hart, D.J.5
Doherty, M.6
-
74
-
-
69949143486
-
The knee osteoarthritis susceptibility locus DVWA on chromosome 3p24.3 is the 5′ part of the split COL6A4 gene
-
Wagener R, Gara SK, Kobbe B, Paulsson M, Zaucke F The knee osteoarthritis susceptibility locus DVWA on chromosome 3p24.3 is the 5′ part of the split COL6A4 gene. Matrix Biol 2009, 28:307-310.
-
(2009)
Matrix Biol
, vol.28
, pp. 307-310
-
-
Wagener, R.1
Gara, S.K.2
Kobbe, B.3
Paulsson, M.4
Zaucke, F.5
-
75
-
-
79953309875
-
Insights into the genetic architecture of osteoarthritis from stage 1 of the arcOGEN study
-
Panoutsopoulou K, Southam L, Elliott KS, et al. Insights into the genetic architecture of osteoarthritis from stage 1 of the arcOGEN study. Ann Rheum Dis 2011, 70(5):864-867.
-
(2011)
Ann Rheum Dis
, vol.70
, Issue.5
, pp. 864-867
-
-
Panoutsopoulou, K.1
Southam, L.2
Elliott, K.S.3
-
76
-
-
78149406119
-
Association of single-nucleotide polymorphisms in HLA class II/III region with knee osteoarthritis
-
Shi D, Zheng Q, Chen D, et al. Association of single-nucleotide polymorphisms in HLA class II/III region with knee osteoarthritis. Osteoarthritis Cartilage 2010, 18(11):1454-1457.
-
(2010)
Osteoarthritis Cartilage
, vol.18
, Issue.11
, pp. 1454-1457
-
-
Shi, D.1
Zheng, Q.2
Chen, D.3
-
77
-
-
80051518333
-
Large Scale replication study of the association between HLA class II/BTNL2 variants and osteoarthritis of the knee in European-descent populations
-
Valdes AM, Styrkarsdottir U, Doherty M, et al. Large Scale replication study of the association between HLA class II/BTNL2 variants and osteoarthritis of the knee in European-descent populations. PLoS ONE 2011, 6(8):e23371.
-
(2011)
PLoS ONE
, vol.6
, Issue.8
-
-
Valdes, A.M.1
Styrkarsdottir, U.2
Doherty, M.3
-
78
-
-
84975742565
-
-
1000 Genomes Project Consortium. A map of human genome variation from population-scale sequencing. Nature 2010;467(7319):1061-73.
-
1000 Genomes Project Consortium. A map of human genome variation from population-scale sequencing. Nature 2010;467(7319):1061-73.
-
-
-
-
79
-
-
67650150235
-
The rho-specific guanine nucleotide exchange factor Dbs regulates breast cancer cell migration
-
Liu Z, Adams HC, Whitehead IP The rho-specific guanine nucleotide exchange factor Dbs regulates breast cancer cell migration. J Biol Chem 2009, 284:15771-15780.
-
(2009)
J Biol Chem
, vol.284
, pp. 15771-15780
-
-
Liu, Z.1
Adams, H.C.2
Whitehead, I.P.3
-
80
-
-
77957934893
-
Tanezumab for the treatment of pain from osteoarthritis of the knee
-
Lane NE, Schnitzer TJ, Birbara CA, et al. Tanezumab for the treatment of pain from osteoarthritis of the knee. N Engl J Med 2010, 363(16):1521-1531.
-
(2010)
N Engl J Med
, vol.363
, Issue.16
, pp. 1521-1531
-
-
Lane, N.E.1
Schnitzer, T.J.2
Birbara, C.A.3
-
81
-
-
77956361934
-
Involvement of different risk factors in clinically severe large joint osteoarthritis according to the presence of hand interphalangeal nodes
-
Valdes AM, McWilliams D, Arden NK, et al. Involvement of different risk factors in clinically severe large joint osteoarthritis according to the presence of hand interphalangeal nodes. Arthritis Rheum 2010, 62(9):2688-2695.
-
(2010)
Arthritis Rheum
, vol.62
, Issue.9
, pp. 2688-2695
-
-
Valdes, A.M.1
McWilliams, D.2
Arden, N.K.3
-
82
-
-
33846839171
-
Differential gene expression of bone anabolic factors and trabecular bone architectural changes in the proximal femoral shaft of primary hip osteoarthritis patients
-
Truong LH, Kuliwaba JS, Tsangari H, Fazzalari NL Differential gene expression of bone anabolic factors and trabecular bone architectural changes in the proximal femoral shaft of primary hip osteoarthritis patients. Arthritis Res Ther 2006, 8(6):R188.
-
(2006)
Arthritis Res Ther
, vol.8
, Issue.6
-
-
Truong, L.H.1
Kuliwaba, J.S.2
Tsangari, H.3
Fazzalari, N.L.4
-
83
-
-
23944456615
-
Synovial tissue inflammation in early and late osteoarthritis
-
Benito MJ, Veale DJ, FitzGerald O, et al. Synovial tissue inflammation in early and late osteoarthritis. Ann Rheum Dis 2005, 64(9):1263-1267.
-
(2005)
Ann Rheum Dis
, vol.64
, Issue.9
, pp. 1263-1267
-
-
Benito, M.J.1
Veale, D.J.2
FitzGerald, O.3
-
84
-
-
0027732734
-
Cytokine expression in synovial membranes of patients with rheumatoid arthritis and osteoarthritis
-
Farahat MN, Yanni G, Poston R, et al. Cytokine expression in synovial membranes of patients with rheumatoid arthritis and osteoarthritis. Ann Rheum Dis 1993, 52(12):870-875.
-
(1993)
Ann Rheum Dis
, vol.52
, Issue.12
, pp. 870-875
-
-
Farahat, M.N.1
Yanni, G.2
Poston, R.3
-
86
-
-
33847059993
-
The role of T cells in the pathogenesis of osteoarthritis
-
Sakkas LI, Platsoucas CD The role of T cells in the pathogenesis of osteoarthritis. Arthritis Rheum 2007, 56(2):409-424.
-
(2007)
Arthritis Rheum
, vol.56
, Issue.2
, pp. 409-424
-
-
Sakkas, L.I.1
Platsoucas, C.D.2
-
87
-
-
3543062889
-
Synovial lining macrophages mediate osteophyte formation during experimental osteoarthritis
-
Blom AB, Van Lent PL, Holthuysen AE, et al. Synovial lining macrophages mediate osteophyte formation during experimental osteoarthritis. Osteoarthritis Cartilage 2004, 12:627-635.
-
(2004)
Osteoarthritis Cartilage
, vol.12
, pp. 627-635
-
-
Blom, A.B.1
Van Lent, P.L.2
Holthuysen, A.E.3
-
88
-
-
0346458587
-
Crucial role of synovial lining macrophages in the promotion of transforming growth factor beta-mediated osteophyte formation
-
Van Lent PL, Blom AB, Van der Kraan P, et al. Crucial role of synovial lining macrophages in the promotion of transforming growth factor beta-mediated osteophyte formation. Arthritis Rheum 2004, 50:103-111.
-
(2004)
Arthritis Rheum
, vol.50
, pp. 103-111
-
-
Van Lent, P.L.1
Blom, A.B.2
Van der Kraan, P.3
-
90
-
-
48549086489
-
Interleukin-1 and transforming growth factor-beta 1 as crucial factors in osteoarthritic cartilage metabolism
-
Pujol JP, Chadjichristos C, Legendre F, Bauge C, Beauchef G, Andriamanalijaona R, et al. Interleukin-1 and transforming growth factor-beta 1 as crucial factors in osteoarthritic cartilage metabolism. Connect Tissue Res 2008, 49(3):293-297.
-
(2008)
Connect Tissue Res
, vol.49
, Issue.3
, pp. 293-297
-
-
Pujol, J.P.1
Chadjichristos, C.2
Legendre, F.3
Bauge, C.4
Beauchef, G.5
Andriamanalijaona, R.6
-
91
-
-
33748505885
-
Contemporary concepts of inflammation, damage and repair in rheumatic diseases
-
Luyten FP, Lories RJ, Verschueren P, et al. Contemporary concepts of inflammation, damage and repair in rheumatic diseases. Best Practice Res Clin Rheum 2006, 20:829-848.
-
(2006)
Best Practice Res Clin Rheum
, vol.20
, pp. 829-848
-
-
Luyten, F.P.1
Lories, R.J.2
Verschueren, P.3
-
92
-
-
0037608724
-
The role of bone metabolism in osteoarthritis
-
Hunter DJ, Spector TD The role of bone metabolism in osteoarthritis. Curr Rheumatol Rep 2003, 5:15-19.
-
(2003)
Curr Rheumatol Rep
, vol.5
, pp. 15-19
-
-
Hunter, D.J.1
Spector, T.D.2
-
93
-
-
0031860152
-
The importance of subchondral bone in osteoarthrosis
-
Burr DB The importance of subchondral bone in osteoarthrosis. Curr Opin Rheumatol 1998, 10:256-262.
-
(1998)
Curr Opin Rheumatol
, vol.10
, pp. 256-262
-
-
Burr, D.B.1
-
94
-
-
0036978279
-
Altered subchondral osteoblast cellular metabolism in osteoarthritis: cytokines, eicosanoids, and growth factors
-
Lajeunesse D Altered subchondral osteoblast cellular metabolism in osteoarthritis: cytokines, eicosanoids, and growth factors. J Musculoskelet Neuronal Interact 2002, 2(6):504-506.
-
(2002)
J Musculoskelet Neuronal Interact
, vol.2
, Issue.6
, pp. 504-506
-
-
Lajeunesse, D.1
-
95
-
-
33744766472
-
BMP Signaling and skeletogenesis
-
Li X, Cao X BMP Signaling and skeletogenesis. Ann NY Acad Sci 2006, 1068:26-40.
-
(2006)
Ann NY Acad Sci
, vol.1068
, pp. 26-40
-
-
Li, X.1
Cao, X.2
-
96
-
-
13944283679
-
BMP receptor signaling is required for postnatal maintenance of articular cartilage
-
Rountree RB, Schoor M, Chen H, et al. BMP receptor signaling is required for postnatal maintenance of articular cartilage. PLoS Biol 2004, 2(11):e355.
-
(2004)
PLoS Biol
, vol.2
, Issue.11
-
-
Rountree, R.B.1
Schoor, M.2
Chen, H.3
-
97
-
-
2942525503
-
Multiple effects of GDF-5 deficiency on skeletal tissues: implications for therapeutic bioengineering
-
Mikic B Multiple effects of GDF-5 deficiency on skeletal tissues: implications for therapeutic bioengineering. Ann Biomed Eng 2004, 32(3):466-476.
-
(2004)
Ann Biomed Eng
, vol.32
, Issue.3
, pp. 466-476
-
-
Mikic, B.1
-
98
-
-
66449089103
-
Large-scale analysis of association between GDF5 and FRZB variants and osteoarthritis of the hip, knee, and hand
-
Evangelou E, Chapman K, Meulenbelt I, et al. Large-scale analysis of association between GDF5 and FRZB variants and osteoarthritis of the hip, knee, and hand. Arthritis Rheum 2009, 60(6):1710-1721.
-
(2009)
Arthritis Rheum
, vol.60
, Issue.6
, pp. 1710-1721
-
-
Evangelou, E.1
Chapman, K.2
Meulenbelt, I.3
-
99
-
-
13944259791
-
An aspartic acid repeat polymorphism in asporin inhibits chondrogenesis and increases susceptibility to osteoarthritis
-
Kizawa H, Kou I, Iida A, Sudo A, et al. An aspartic acid repeat polymorphism in asporin inhibits chondrogenesis and increases susceptibility to osteoarthritis. Nat Genet 2005, 37(2):138-144.
-
(2005)
Nat Genet
, vol.37
, Issue.2
, pp. 138-144
-
-
Kizawa, H.1
Kou, I.2
Iida, A.3
Sudo, A.4
-
100
-
-
33751300226
-
Replication of the association of the aspartic acid repeat polymorphism in the asporin gene with knee-osteoarthritis susceptibility in Han Chinese
-
Jiang Q, Shi D, Yi L, Ikegawa S, Wang Y, Nakamura T, et al. Replication of the association of the aspartic acid repeat polymorphism in the asporin gene with knee-osteoarthritis susceptibility in Han Chinese. J Hum Genet 2006, 51(12):1068-1072.
-
(2006)
J Hum Genet
, vol.51
, Issue.12
, pp. 1068-1072
-
-
Jiang, Q.1
Shi, D.2
Yi, L.3
Ikegawa, S.4
Wang, Y.5
Nakamura, T.6
-
101
-
-
34547093391
-
Association of the aspartic acid-repeat polymorphism in the asporin gene with age at onset of knee osteoarthritis in Han Chinese population
-
Shi D, Nakamura T, Dai J, et al. Association of the aspartic acid-repeat polymorphism in the asporin gene with age at onset of knee osteoarthritis in Han Chinese population. J Hum Genet 2007, 52(8):664-667.
-
(2007)
J Hum Genet
, vol.52
, Issue.8
, pp. 664-667
-
-
Shi, D.1
Nakamura, T.2
Dai, J.3
-
102
-
-
42749087329
-
Aspartic acid repeat polymorphism of the asporin gene with susceptibility to osteoarthritis of the knee in a Korean population
-
Song JH, Lee HS, Kim CJ, et al. Aspartic acid repeat polymorphism of the asporin gene with susceptibility to osteoarthritis of the knee in a Korean population. Knee 2008, 15(3):191-195.
-
(2008)
Knee
, vol.15
, Issue.3
, pp. 191-195
-
-
Song, J.H.1
Lee, H.S.2
Kim, C.J.3
-
103
-
-
50949126590
-
Absence of association of asporin polymorphisms and osteoarthritis susceptibility in US Caucasians
-
Atif U, Philip A, Aponte J, et al. Absence of association of asporin polymorphisms and osteoarthritis susceptibility in US Caucasians. Osteoarthritis Cartilage 2008, 16(10):1174-1177.
-
(2008)
Osteoarthritis Cartilage
, vol.16
, Issue.10
, pp. 1174-1177
-
-
Atif, U.1
Philip, A.2
Aponte, J.3
-
104
-
-
0033986279
-
OA-like changes in the murine knee joint resulting from intra-articular TGFβ injections
-
Van Beuningen HM, Glansbeek HL, van der Kraan PM, van den Berg WB OA-like changes in the murine knee joint resulting from intra-articular TGFβ injections. Osteoarthritis Cartilage 2000, 8:25-33.
-
(2000)
Osteoarthritis Cartilage
, vol.8
, pp. 25-33
-
-
Van Beuningen, H.M.1
Glansbeek, H.L.2
van der Kraan, P.M.3
van den Berg, W.B.4
-
105
-
-
0036644328
-
Inhibition of endogenous TGFβ during experimental OA prevents osteophyte formation and impairs cartilage repair
-
Scharstuhl A, Glansbeek HL, van Beuningen HM, Vitters EL, van der Kraan PM, van den Berg WB Inhibition of endogenous TGFβ during experimental OA prevents osteophyte formation and impairs cartilage repair. J Immunol 2002, 169:507-514.
-
(2002)
J Immunol
, vol.169
, pp. 507-514
-
-
Scharstuhl, A.1
Glansbeek, H.L.2
van Beuningen, H.M.3
Vitters, E.L.4
van der Kraan, P.M.5
van den Berg, W.B.6
-
106
-
-
67649216115
-
Increase in ALK1/ALK5 ratio as a cause for elevated MMP-13 expression in osteoarthritis in humans and mice
-
Blaney Davidson EN, Remst DF, Vitters EL, et al. Increase in ALK1/ALK5 ratio as a cause for elevated MMP-13 expression in osteoarthritis in humans and mice. J Immunol 2009, 182:7937-7945.
-
(2009)
J Immunol
, vol.182
, pp. 7937-7945
-
-
Blaney Davidson, E.N.1
Remst, D.F.2
Vitters, E.L.3
-
107
-
-
77955411535
-
Konttinen Aberrant hypertrophy in Smad3-deficient murine chondrocytes is rescued by restoring TGFβ-activated kinase 1/activating transcription factor 2 signaling: a potential clinical implication for osteoarthritis
-
Li TF, Gao L, Sheu TJ, Sampson ER, Flick LM Konttinen Aberrant hypertrophy in Smad3-deficient murine chondrocytes is rescued by restoring TGFβ-activated kinase 1/activating transcription factor 2 signaling: a potential clinical implication for osteoarthritis. Arthritis Rheum 2010, 62:2359-2369.
-
(2010)
Arthritis Rheum
, vol.62
, pp. 2359-2369
-
-
Li, T.F.1
Gao, L.2
Sheu, T.J.3
Sampson, E.R.4
Flick, L.M.5
-
108
-
-
59649110626
-
TSH-based protocol, tablet instability, and absorption effects on L-T4 bioequivalence
-
Eisenberg M, Distefano JJ TSH-based protocol, tablet instability, and absorption effects on L-T4 bioequivalence. Thyroid 2009, 19(2):103-110.
-
(2009)
Thyroid
, vol.19
, Issue.2
, pp. 103-110
-
-
Eisenberg, M.1
Distefano, J.J.2
-
109
-
-
79955557839
-
Osteoarthritis susceptibility genes influence the association between hip morphology and osteoarthritis
-
Waarsing JH, Kloppenburg M, Slagboom PE, et al. Osteoarthritis susceptibility genes influence the association between hip morphology and osteoarthritis. Arthritis Rheum 2011, 63(5):1349-1354.
-
(2011)
Arthritis Rheum
, vol.63
, Issue.5
, pp. 1349-1354
-
-
Waarsing, J.H.1
Kloppenburg, M.2
Slagboom, P.E.3
-
110
-
-
66149180583
-
Developments in the scientific understanding of osteoarthritis
-
Abramson SB, Attur M Developments in the scientific understanding of osteoarthritis. Arthritis Res Ther 2009, 11(3):227.
-
(2009)
Arthritis Res Ther
, vol.11
, Issue.3
, pp. 227
-
-
Abramson, S.B.1
Attur, M.2
-
111
-
-
77952551250
-
A meta-analysis of interleukin-6 promoter polymorphisms on risk of hip and knee osteoarthritis
-
Valdes AM, Arden NK, Tamm A, et al. A meta-analysis of interleukin-6 promoter polymorphisms on risk of hip and knee osteoarthritis. Osteoarthritis Cartilage 2010, 18(5):699-704.
-
(2010)
Osteoarthritis Cartilage
, vol.18
, Issue.5
, pp. 699-704
-
-
Valdes, A.M.1
Arden, N.K.2
Tamm, A.3
-
112
-
-
78650968063
-
The (-765 G>C) promoter variant of the COX-2/PTGS2 gene is associated with a lower risk for end-stage hip and knee osteoarthritis
-
Schneider EM, Du W, Fiedler J, et al. The (-765 G>C) promoter variant of the COX-2/PTGS2 gene is associated with a lower risk for end-stage hip and knee osteoarthritis. Ann Rheum Dis 2011, 70(8):1458-1460.
-
(2011)
Ann Rheum Dis
, vol.70
, Issue.8
, pp. 1458-1460
-
-
Schneider, E.M.1
Du, W.2
Fiedler, J.3
-
113
-
-
78149489455
-
Serum C reactive protein levels and genetic variation in the CRP gene are not associated with the prevalence, incidence or progression of osteoarthritis independent of body mass index
-
Kerkhof HJ, Bierma-Zeinstra SM, Castano-Betancourt MC, et al. Serum C reactive protein levels and genetic variation in the CRP gene are not associated with the prevalence, incidence or progression of osteoarthritis independent of body mass index. Ann Rheum Dis 2010, 69(11):1976-1982.
-
(2010)
Ann Rheum Dis
, vol.69
, Issue.11
, pp. 1976-1982
-
-
Kerkhof, H.J.1
Bierma-Zeinstra, S.M.2
Castano-Betancourt, M.C.3
-
114
-
-
57249115817
-
Tumour necrosis factor alpha -308G/A gene polymorphism: lack of association with knee osteoarthritis in a Turkish population
-
Sezgin M, Barlas IO, Ankarali HC, et al. Tumour necrosis factor alpha -308G/A gene polymorphism: lack of association with knee osteoarthritis in a Turkish population. Clin Exp Rheumatol 2008, 26(5):763-768.
-
(2008)
Clin Exp Rheumatol
, vol.26
, Issue.5
, pp. 763-768
-
-
Sezgin, M.1
Barlas, I.O.2
Ankarali, H.C.3
-
115
-
-
61749093337
-
Wnt signaling and osteoarthritis
-
Luyten FP, Tylzanowski P, Lories RJ Wnt signaling and osteoarthritis. Bone 2009, 44(4):522-527.
-
(2009)
Bone
, vol.44
, Issue.4
, pp. 522-527
-
-
Luyten, F.P.1
Tylzanowski, P.2
Lories, R.J.3
-
116
-
-
33646372430
-
Frizzled-related protein variants are risk factors for hip osteoarthritis
-
Lane NE, Lian K, Nevitt MC, et al. Frizzled-related protein variants are risk factors for hip osteoarthritis. Arthritis Rheum 2006, 54(4):1246-1254.
-
(2006)
Arthritis Rheum
, vol.54
, Issue.4
, pp. 1246-1254
-
-
Lane, N.E.1
Lian, K.2
Nevitt, M.C.3
-
117
-
-
33846236311
-
Sex and ethnic differences in the association of ASPN, CALM1, COL2A1, COMP, and FRZB with genetic susceptibility to osteoarthritis of the knee
-
Valdes AM, Loughlin J, Oene MV, et al. Sex and ethnic differences in the association of ASPN, CALM1, COL2A1, COMP, and FRZB with genetic susceptibility to osteoarthritis of the knee. Arthritis Rheum 2007, 56(1):137-146.
-
(2007)
Arthritis Rheum
, vol.56
, Issue.1
, pp. 137-146
-
-
Valdes, A.M.1
Loughlin, J.2
Oene, M.V.3
-
118
-
-
48349084103
-
Radiographic osteoarthritis at three joint sites and FRZB, LRP5, and LRP6 polymorphisms in two population-based cohorts
-
Kerkhof JM, Uitterlinden AG, Valdes AM, et al. Radiographic osteoarthritis at three joint sites and FRZB, LRP5, and LRP6 polymorphisms in two population-based cohorts. Osteoarthritis Cartilage 2008, 16(10):1141-1149.
-
(2008)
Osteoarthritis Cartilage
, vol.16
, Issue.10
, pp. 1141-1149
-
-
Kerkhof, J.M.1
Uitterlinden, A.G.2
Valdes, A.M.3
-
119
-
-
0034080616
-
Analysis of discordance between radiographic change and knee pain in osteoarthritis of the knee
-
Hannan MT, Felson DT, Pincus T Analysis of discordance between radiographic change and knee pain in osteoarthritis of the knee. J Rheumatol 2000, 27:1513-1517.
-
(2000)
J Rheumatol
, vol.27
, pp. 1513-1517
-
-
Hannan, M.T.1
Felson, D.T.2
Pincus, T.3
-
120
-
-
65649152622
-
The natural history of disability and its determinants in adults with lower limb musculoskeletal pain
-
Ayis S, Dieppe P The natural history of disability and its determinants in adults with lower limb musculoskeletal pain. J Rheumatol 2009, 36(3):583-591.
-
(2009)
J Rheumatol
, vol.36
, Issue.3
, pp. 583-591
-
-
Ayis, S.1
Dieppe, P.2
-
121
-
-
59649093445
-
A functional polymorphism in the catechol-O-methyltransferase gene is associated with osteoarthritis-related pain
-
van Meurs JB, Uitterlinden AG, Stolk L, et al. A functional polymorphism in the catechol-O-methyltransferase gene is associated with osteoarthritis-related pain. Arthritis Rheum 2009, 60(2):628-629.
-
(2009)
Arthritis Rheum
, vol.60
, Issue.2
, pp. 628-629
-
-
van Meurs, J.B.1
Uitterlinden, A.G.2
Stolk, L.3
-
122
-
-
77950429077
-
Pain perception is altered by a nucleotide polymorphism in SCN9A
-
Reimann F, Cox JJ, Belfer I, et al. Pain perception is altered by a nucleotide polymorphism in SCN9A. Proc Natl Acad Sci USA 2010, 107(11):5148-5153.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, Issue.11
, pp. 5148-5153
-
-
Reimann, F.1
Cox, J.J.2
Belfer, I.3
-
123
-
-
84858011185
-
Role of the Na(V)1.7 R1150W amino acid change in susceptibility to symptomatic knee osteoarthritis and multiple regional pain
-
Valdes AM, Arden NK, Vaughn FL, et al. Role of the Na(V)1.7 R1150W amino acid change in susceptibility to symptomatic knee osteoarthritis and multiple regional pain. Arthritis Care Res (Hoboken) 2011, 63(3):440-444.
-
(2011)
Arthritis Care Res (Hoboken)
, vol.63
, Issue.3
, pp. 440-444
-
-
Valdes, A.M.1
Arden, N.K.2
Vaughn, F.L.3
-
124
-
-
70350028725
-
Finding common susceptibility variants for complex disease: past, present and future
-
Panoutsopoulou K, Zeggini E Finding common susceptibility variants for complex disease: past, present and future. Brief Funct Genomic Proteomic 2009, 8(5):345-352.
-
(2009)
Brief Funct Genomic Proteomic
, vol.8
, Issue.5
, pp. 345-352
-
-
Panoutsopoulou, K.1
Zeggini, E.2
-
125
-
-
79959764259
-
Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration
-
Janssens AC, Ioannidis JP, Bedrosian S, et al. Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration. Eur J Epidemiol 2011, 26(4):313-337.
-
(2011)
Eur J Epidemiol
, vol.26
, Issue.4
, pp. 313-337
-
-
Janssens, A.C.1
Ioannidis, J.P.2
Bedrosian, S.3
-
126
-
-
37749024290
-
The additive effect of individual genes in predicting risk of knee osteoarthritis
-
Valdes AM, Doherty M, Spector TD The additive effect of individual genes in predicting risk of knee osteoarthritis. Ann Rheum Dis 2008, 67(1):124-127.
-
(2008)
Ann Rheum Dis
, vol.67
, Issue.1
, pp. 124-127
-
-
Valdes, A.M.1
Doherty, M.2
Spector, T.D.3
-
127
-
-
77957728949
-
Prediction model for knee osteoarthritis based on genetic and clinical information
-
Takahashi H, Nakajima M, Ozaki K, Tanaka T, Kamatani N, Ikegawa S Prediction model for knee osteoarthritis based on genetic and clinical information. Arthritis Res Ther 2010, 12(5):R187.
-
(2010)
Arthritis Res Ther
, vol.12
, Issue.5
-
-
Takahashi, H.1
Nakajima, M.2
Ozaki, K.3
Tanaka, T.4
Kamatani, N.5
Ikegawa, S.6
-
128
-
-
66649130580
-
Advances in measuring the effect of individual predictors of cardiovascular risk: the role of reclassification measures
-
Cook NR, Ridker PM Advances in measuring the effect of individual predictors of cardiovascular risk: the role of reclassification measures. Ann Intern Med 2009, 150(11):795-802.
-
(2009)
Ann Intern Med
, vol.150
, Issue.11
, pp. 795-802
-
-
Cook, N.R.1
Ridker, P.M.2
-
129
-
-
73849094087
-
Assessing the performance of prediction models: a framework for traditional and novel measures
-
Steyerberg EW, Vickers AJ, Cook NR, Gerds T, Gonen M, Obuchowski N, et al. Assessing the performance of prediction models: a framework for traditional and novel measures. Epidemiology 2010, 21(1):128-138.
-
(2010)
Epidemiology
, vol.21
, Issue.1
, pp. 128-138
-
-
Steyerberg, E.W.1
Vickers, A.J.2
Cook, N.R.3
Gerds, T.4
Gonen, M.5
Obuchowski, N.6
-
130
-
-
65549129157
-
Prediction model for prevalence and incidence of advanced age-related macular degeneration based on genetic, demographic, and environmental variables
-
Seddon JM, Reynolds R, Maller J, et al. Prediction model for prevalence and incidence of advanced age-related macular degeneration based on genetic, demographic, and environmental variables. Invest Ophthalmol Vis Sci 2009, 50:2044-2053.
-
(2009)
Invest Ophthalmol Vis Sci
, vol.50
, pp. 2044-2053
-
-
Seddon, J.M.1
Reynolds, R.2
Maller, J.3
-
131
-
-
61649123125
-
Molecular prediction of disease risk and severity in a large Dutch Crohn's disease cohort
-
Weersma RK, Stokkers PC, van Bodegraven AA, et al. Molecular prediction of disease risk and severity in a large Dutch Crohn's disease cohort. Gut 2009, 58:388-395.
-
(2009)
Gut
, vol.58
, pp. 388-395
-
-
Weersma, R.K.1
Stokkers, P.C.2
van Bodegraven, A.A.3
-
132
-
-
50849100090
-
Polygenic determinants of severe hypertriglyceridemia
-
Wang J, Ban MR, Zou GY, Cao H, Lin T, et al. Polygenic determinants of severe hypertriglyceridemia. Hum Mol Genet. 2008, 17:2894-2899.
-
(2008)
Hum Mol Genet.
, vol.17
, pp. 2894-2899
-
-
Wang, J.1
Ban, M.R.2
Zou, G.Y.3
Cao, H.4
Lin, T.5
-
133
-
-
57049176037
-
The management of osteoarthritis: an overview and call to appropriate conservative treatment
-
Hunter DJ, Lo GH The management of osteoarthritis: an overview and call to appropriate conservative treatment. Med Clin North Am 2009, 93(1):127-143.
-
(2009)
Med Clin North Am
, vol.93
, Issue.1
, pp. 127-143
-
-
Hunter, D.J.1
Lo, G.H.2
-
134
-
-
32544454827
-
Total joint replacement in osteoarthritis
-
Katz JN Total joint replacement in osteoarthritis. Best Pract Res Clin Rheumatol 2006, 20(1):145-153.
-
(2006)
Best Pract Res Clin Rheumatol
, vol.20
, Issue.1
, pp. 145-153
-
-
Katz, J.N.1
-
135
-
-
84865293654
-
Inverse relationship between preoperative radiographic severity and postoperative pain in patients with osteoarthritis who have undergone total joint arthroplasty
-
[Epub ahead of print]
-
Valdes AM, Doherty SA, Zhang W, Muir KR, Maciewicz RA, Doherty M Inverse relationship between preoperative radiographic severity and postoperative pain in patients with osteoarthritis who have undergone total joint arthroplasty. Semin Arthritis Rheum 2011, [Epub ahead of print].
-
(2011)
Semin Arthritis Rheum
-
-
Valdes, A.M.1
Doherty, S.A.2
Zhang, W.3
Muir, K.R.4
Maciewicz, R.A.5
Doherty, M.6
|