Genome-wide Association Scan Identifies a Prostaglandin-Endoperoxide Synthase 2 Variant Involved in Risk of Knee Osteoarthritis

American Journal of Human Genetics

Volumn 82, Issue 6, 2008, Pages 1231-1240

  Valdes, Ana M ^a   Loughlin, John ^b,c   Timms, Kirsten M ^d   van Meurs, Joyce J B ^e   Southam, Lorraine ^b   Wilson, Scott G ^f   Doherty, Sally ^g   Lories, Rik J ^h   Luyten, Frank P ^h   Gutin, Alexander ^d   Abkevich, Victor ^d   Ge, Dongliang ⁱ   Hofman, Albert ^e   Uitterlinden, André G ^e   Hart, Deborah J ^a   Zhang, Feng ^a   Zhai, Guangju ^a   Egli, Rainer J ^b   Doherty, Michael ^g   Lanchbury, Jerry ^d   Spector, Tim D ^a   more..

^a ST THOMAS HOSPITAL   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c NEWCASTLE UNIVERSITY   (United Kingdom)

^d Myriad Genetic Laboratories   (United States)

^e ERASMUS MEDICAL CENTER   (Netherlands)

^f UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^g UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^h Laboratory for Skeletal Development and Joint Disorders   (Belgium)

ⁱ DUKE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOOXYGENASE 2; MESSENGER RNA; PROSTAGLANDIN SYNTHASE; PROSTAGLANDIN SYNTHASE 2;

ADULT; AGED; ALLELE; ARTICLE; CHROMOSOME MAP; CONTROLLED STUDY; DNA POLYMORPHISM; FEMALE; GENE; GENE EXPRESSION; GENE LINKAGE DISEQUILIBRIUM; GENOME; GENOTYPE; HUMAN; KNEE OSTEOARTHRITIS; MAJOR CLINICAL STUDY; MALE; PHOSPHOLIPASE A2 GENE; PRIORITY JOURNAL; PROSTAGLANDIN ENDOPEROXIDE SYNTHASE 2 GENE;

AGED; AGED, 80 AND OVER; ALLELES; BASE SEQUENCE; CASE-CONTROL STUDIES; CHONDROCYTES; COHORT STUDIES; CYCLOOXYGENASE 2; DNA PRIMERS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOMICS; GROUP IV PHOSPHOLIPASES A2; HUMANS; LINKAGE DISEQUILIBRIUM; MIDDLE AGED; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OSTEOARTHRITIS, KNEE; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS; RNA, MESSENGER; VARIATION (GENETICS);

EID: 44449153906     PISSN: 00029297     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ajhg.2008.04.006     Document Type: Article

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