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Volumn 36, Issue 9, 2013, Pages 753-758

Renin-angiotensin-aldosterone system has a pivotal role in cognitive impairment

Author keywords

blood brain barrier; cognitive impairment; RAAS inhibitors

Indexed keywords

ACETYLCHOLINE; ALACEPRIL; ALISKIREN; AZILSARTAN; BENAZEPRIL; CANDESARTAN; CILAZAPRIL; DELAPRIL; ENALAPRIL; EPLERENONE; IMIDAPRIL; INDAPAMIDE; IRBESARTAN; LOSARTAN; NITRENDIPINE; OLMESARTAN; PERINDOPRIL; QUINAPRIL; SPIRONOLACTONE; SUBSTANCE P; TAU PROTEIN; TELMISARTAN; TEMOCAPRIL; TRANDOLAPRIL; VALSARTAN;

EID: 84883885656     PISSN: 09169636     EISSN: 13484214     Source Type: Journal    
DOI: 10.1038/hr.2013.51     Document Type: Review
Times cited : (31)

References (93)
  • 1
    • 55449106821 scopus 로고    scopus 로고
    • Cognitive dysfunction and physical disability are associated with mortality in extremely elderly patients
    • Hoshide S, Ishikawa J, Eguchi K, Oowada T, Shimada K, Kario K. Cognitive dysfunction and physical disability are associated with mortality in extremely elderly patients. Hypertens Res 2008; 31: 1331-1338.
    • (2008) Hypertens Res , vol.31 , pp. 1331-1338
    • Hoshide, S.1    Ishikawa, J.2    Eguchi, K.3    Oowada, T.4    Shimada, K.5    Kario, K.6
  • 3
    • 0029617996 scopus 로고
    • The association between midlife blood pressure levels and late-life cognitive function: The Honolulu-Asia aging study
    • DOI 10.1001/jama.274.23.1846
    • Launer LJ, Masaki K, Petrovitch H, Foley D, Havlik RJ. The association between midlife blood-pressure levels and late-life cognitive function-the Honolulu-Asia Aging Study. JAMA 1995; 274: 1846-1851. (Pubitemid 26001260)
    • (1995) Journal of the American Medical Association , vol.274 , Issue.23 , pp. 1846-1851
    • Launer, L.J.1    Masaki, K.2    Petrovitch, H.3    Foley, D.4    Havlik, R.J.5
  • 6
    • 1842528072 scopus 로고    scopus 로고
    • Cerebral infarctions and the likelihood of dementia from Alzheimer disease pathology
    • Schneider JA, Wilson RS, Bienias JL, Evans DA, Bennett DA. Cerebral infarctions and the likelihood of dementia from Alzheimer disease pathology. Neurology 2004; 62: 1148-1155. (Pubitemid 38456510)
    • (2004) Neurology , vol.62 , Issue.7 , pp. 1148-1155
    • Schneider, J.A.1    Wilson, R.S.2    Bienias, J.L.3    Evans, D.A.4    Bennett, D.A.5
  • 12
    • 74949131237 scopus 로고    scopus 로고
    • Use of angiotensin receptor blockers and risk of dementia in a predominantly male population: Prospective cohort analysis
    • Li NC, Lee A, Whitmer RA, Kivipelto M, Lawler E, Kazis LE, Wolozin B. Use of angiotensin receptor blockers and risk of dementia in a predominantly male population: prospective cohort analysis. BMJ 2010; 340: b5465.
    • (2010) BMJ , vol.340
    • Li, N.C.1    Lee, A.2    Whitmer, R.A.3    Kivipelto, M.4    Lawler, E.5    Kazis, L.E.6    Wolozin, B.7
  • 14
    • 0037161304 scopus 로고    scopus 로고
    • The relationship of hypertension in the elderly to AD, vascular dementia, and cognitive function
    • Posner HB, Tang MX, Luchsinger J, Lantigua R, Stern Y, Mayeux R. The relationship of hypertension in the elderly to AD, vascular dementia, and cognitive function. Neurology 2002; 58: 1175-1181. (Pubitemid 34411860)
    • (2002) Neurology , vol.58 , Issue.8 , pp. 1175-1181
    • Posner, H.B.1    Tang, M.-X.2    Luchsinger, J.3    Lantigua, R.4    Stern, Y.5    Mayeux, R.6
  • 17
    • 2442668997 scopus 로고    scopus 로고
    • The relationship between blood pressure and cognitive performance in the Third National Health and Nutrition Examination Survey (NHANES III)
    • DOI 10.1097/01.psy.0000127870.64234.9f
    • Suhr JA, Stewart JC, France CR. The relationship between blood pressure and cognitive performance in the third national health and nutrition examination survey (NHANES III). Psychosom Med 2004; 66: 291-297. (Pubitemid 38668395)
    • (2004) Psychosomatic Medicine , vol.66 , Issue.3 , pp. 291-297
    • Suhr, J.A.1    Stewart, J.C.2    France, C.R.3
  • 18
    • 25844515550 scopus 로고    scopus 로고
    • Blood pressure and cognitive function in an African-American and a Caucasian-American sample: The Maine-Syracuse Study
    • DOI 10.1097/01.psy.0000171164.50990.80
    • Robbins MA, Elias MF, Elias PK, Budge MM. Blood pressure and cognitive function in an African-American and a Caucasian-American sample: the Maine-Syracuse Study. Psychosom Med 2005; 67: 707-714. (Pubitemid 41396016)
    • (2005) Psychosomatic Medicine , vol.67 , Issue.5 , pp. 707-714
    • Robbins, M.A.1    Elias, M.F.2    Elias, P.K.3    Budge, M.M.4
  • 19
    • 40149084310 scopus 로고    scopus 로고
    • High blood pressure, hypertension, and high pulse pressure are associated with poorer cognitive function in persons aged 60 and older: The Third National Health and Nutrition Examination Survey
    • DOI 10.1111/j.1532-5415.2007.01592.x
    • Obisesan TO, Obisesan OA, Martins S, Alamgir L, Bond V, Maxwell C, Gillum RF. High blood pressure, hypertension, and high pulse pressure are associated with poorer cognitive function in persons aged 60 and older: the Third National Health and Nutrition Examination Survey. J Am Geriatr Soc 2008; 56: 501-509. (Pubitemid 351327944)
    • (2008) Journal of the American Geriatrics Society , vol.56 , Issue.3 , pp. 501-509
    • Obisesan, T.O.1    Obisesan, O.A.2    Martins, S.3    Alamgir, L.4    Bond, V.5    Maxwell, C.6    Gillum, R.F.7
  • 21
    • 0031951913 scopus 로고    scopus 로고
    • Hypertension is related to cognitive impairment: A 20-year follow-up of 999 men
    • Kilander L, Nyman H, Boberg M, Hansson L, Lithell H. Hypertension is related to cognitive impairment-A 20-year follow-up of 999 men. Hypertension 1998; 31: 780-786. (Pubitemid 28108576)
    • (1998) Hypertension , vol.31 , Issue.3 , pp. 780-786
    • Kilander, L.1    Nyman, H.2    Boberg, M.3    Hansson, L.4    Lithell, H.5
  • 22
    • 7244236386 scopus 로고    scopus 로고
    • Blood pressure-related cognitive decline: Does age make a difference?
    • DOI 10.1161/01.HYP.0000145858.07252.99
    • Elias PK, Elias MF, Robbins MA, Budge MM. Blood pressure-related cognitive decline-Does age make a difference? Hypertension 2004; 44: 631-636. (Pubitemid 39435231)
    • (2004) Hypertension , vol.44 , Issue.5 , pp. 631-636
    • Elias, P.K.1    Elias, M.F.2    Robbins, M.A.3    Budge, M.M.4
  • 23
    • 0030955583 scopus 로고    scopus 로고
    • Blood pressure and performance on the Mini-Mental State Examination in the very old: Cross-sectional and longitudinal data from the Kungsholmen project
    • Guo ZC, Fratiglioni L, Winblad B, Viitanen M. Blood pressure and performance on the Mini-Mental State Examination in the very old-Cross-sectional and longitudinal data from the Kungsholmen Project. Am J Epidemiol 1997; 145: 1106-1113. (Pubitemid 27272940)
    • (1997) American Journal of Epidemiology , vol.145 , Issue.12 , pp. 1106-1113
    • Guo, Z.1    Fratiglioni, L.2    Winblad, B.3    Viitanen, M.4
  • 24
    • 14644406855 scopus 로고    scopus 로고
    • Nonlinear relations of blood pressure to cognitive function: The Baltimore longitudinal study of aging
    • DOI 10.1161/01.HYP.0000156744.44218.74
    • Waldstein SR, Giggey PP, Thayer JF, Zonderman AB. Nonlinear relations of blood pressure to cognitive function-The Baltimore Longitudinal Study of Aging. Hypertension 2005; 45: 374-379. (Pubitemid 40315806)
    • (2005) Hypertension , vol.45 , Issue.3 , pp. 374-379
    • Waldstein, S.R.1    Giggey, P.P.2    Thayer, J.F.3    Zonderman, A.B.4
  • 26
    • 0029988543 scopus 로고    scopus 로고
    • Is the cognitive function of older patients affected by antihypertensive treatment? Results from 54 months of the Medical Research Council's treatment trial of hypertension in older adults
    • Prince MJ, Bird AS, Blizard RA, Mann AH. Is the cognitive function of older patients affected by antihypertensive treatment? Results from 54 months of the Medical Research Council's treatment trial of hypertension in older adults. BMJ 1996; 312: 801-805. (Pubitemid 26099297)
    • (1996) British Medical Journal , vol.312 , Issue.7034 , pp. 801-805
    • Prince, M.J.1    Bird, A.S.2    Blizard, R.A.3    Mann, A.H.4
  • 31
    • 0038669268 scopus 로고    scopus 로고
    • Effects of blood pressure lowering with perindopril and indapamide therapy on dementia and cognitive decline in patients with cerebrovascular disease
    • DOI 10.1001/archinte.163.9.1069
    • Tzourio C, Anderson C, Chapman N, Woodward M, Neal B, MacMahon S, Chalmers J. Effects of blood pressure lowering with perindopril and indapamide therapy on dementia and cognitive decline in patients with cerebrovascular disease. Arch Intern Med 2003; 163: 1069-1075. (Pubitemid 36548935)
    • (2003) Archives of Internal Medicine , vol.163 , Issue.9 , pp. 1069-1075
    • Tzourio, C.1    Anderson, C.2    Chapman, N.3    Woodward, M.4    Neal, B.5    MacMahon, S.6    Chalmers, J.7
  • 33
    • 0028901733 scopus 로고
    • The angiotensin receptor subtype At1a predominates in rat forebrain areas involved in blood-pressure, body-fluid homeostasis and neuroendocrine control
    • Lenkei Z, Corvol P, Llorenscortes C. The angiotensin receptor subtype At1a predominates in rat forebrain areas involved in blood-pressure, body-fluid homeostasis and neuroendocrine control. Brain Res Mol Brain Res 1995; 30: 53-60.
    • (1995) Brain Res Mol Brain Res , vol.30 , pp. 53-60
    • Lenkei, Z.1    Corvol, P.2    Llorenscortes, C.3
  • 34
    • 0032583132 scopus 로고    scopus 로고
    • Angiotensin II in central nervous system physiology
    • DOI 10.1016/S0167-0115(98)00122-0, PII S0167011598001220
    • Phillips MI, Sumners C. Angiotensin II in central nervous system physiology. Regul Pep 1998; 78: 1-11. (Pubitemid 28561511)
    • (1998) Regulatory Peptides , vol.78 , Issue.1-3 , pp. 1-11
    • Phillips, M.I.1    Sumners, C.2
  • 35
    • 0038606899 scopus 로고    scopus 로고
    • Brain renin-angiotensin system dysfunction in hypertension: Recent advances and perspectives
    • DOI 10.1038/sj.bjp.0705262
    • Veerasingham SJ, Raizada MK. Brain renin-angiotensin system dysfunction in hypertension: recent advances and perspectives. Br J Pharmacol 2003; 139: 191-202. (Pubitemid 36760351)
    • (2003) British Journal of Pharmacology , vol.139 , Issue.2 , pp. 191-202
    • Veerasingham, S.J.1    Raizada, M.K.2
  • 42
    • 80052801105 scopus 로고    scopus 로고
    • Multiple cellular and molecular mechanisms are involved in human Abeta clearance by transplanted adult astrocytes
    • Pihlaja R, Koistinaho J, Kauppinen R, Sandholm J, Tanila H, Koistinaho M. Multiple cellular and molecular mechanisms are involved in human Abeta clearance by transplanted adult astrocytes. Glia 2011; 59: 1643-1657.
    • (2011) Glia , vol.59 , pp. 1643-1657
    • Pihlaja, R.1    Koistinaho, J.2    Kauppinen, R.3    Sandholm, J.4    Tanila, H.5    Koistinaho, M.6
  • 44
    • 70350512081 scopus 로고    scopus 로고
    • Brain renin-angiotensin system in cognitive function: Pre-clinical findings and implications for prevention and treatment of dementia
    • Ciobica A, Bild W, Hritcu L, Haulica I. Brain renin-angiotensin system in cognitive function: pre-clinical findings and implications for prevention and treatment of dementia. Acta Neurologica Belgica 2009; 109: 171-180.
    • (2009) Acta Neurologica Belgica , vol.109 , pp. 171-180
    • Ciobica, A.1    Bild, W.2    Hritcu, L.3    Haulica, I.4
  • 45
    • 33847791727 scopus 로고    scopus 로고
    • Is inhibition of the renin-angiotensin system a new treatment option for Alzheimer's disease?
    • DOI 10.1016/S1474-4422(07)70077-7, PII S1474442207700777
    • Kehoe PG, Wilcock GK. Is inhibition of the renin-angiotensin system a new treatment option for Alzheimer's disease? Lancet Neurology 2007; 6: 373-378. (Pubitemid 46389616)
    • (2007) Lancet Neurology , vol.6 , Issue.4 , pp. 373-378
    • Kehoe, P.G.1    Wilcock, G.K.2
  • 49
    • 84878780550 scopus 로고    scopus 로고
    • Impact of angiotensin receptor blockers on Alzheimer disease neuropathology in a large brain autopsy series
    • Hajjar I, Brown L, Mack WJ, Chui H. Impact of angiotensin receptor blockers on Alzheimer disease neuropathology in a large brain autopsy series. Arch Neurol 2012: 1-7.
    • Arch Neurol , vol.2012 , pp. 1-7
    • Hajjar, I.1    Brown, L.2    MacK, W.J.3    Chui, H.4
  • 50
    • 51549095032 scopus 로고    scopus 로고
    • Effects of hypertension therapy based on eprosartan on systolic arterial blood pressure and cognitive function: Primary results of the Observational Study on Cognitive function and Systolic Blood Pressure Reduction open-label study
    • Hanon O, Berrou JP, Negre-Pages L, Goch JH, Nadhazi Z, Petrella R, Sedefdjian A, Sevenier F, Shlyakhto EV, Pathak A. Effects of hypertension therapy based on eprosartan on systolic arterial blood pressure and cognitive function: primary results of the Observational Study on Cognitive function And Systolic Blood Pressure Reduction open-label study. J Hypertens 2008; 26: 1642-1650.
    • (2008) J Hypertens , vol.26 , pp. 1642-1650
    • Hanon, O.1    Berrou, J.P.2    Negre-Pages, L.3    Goch, J.H.4    Nadhazi, Z.5    Petrella, R.6    Sedefdjian, A.7    Sevenier, F.8    Shlyakhto, E.V.9    Pathak, A.10
  • 51
    • 33744909553 scopus 로고    scopus 로고
    • Effect of telmisartan/hydrochlorothiazide vs lisinopril/ hydrochlorothiazide combination on ambulatory blood pressure and cognitive function in elderly hypertensive patients
    • Fogari R, Mugellini A, Zoppi A, Lazzari P, Destro M, Rinaldi A, Preti P. Effect of telmisartan/hydrochlorothiazide vs lisinopril/hydrochlorothiazide combination on ambulatory blood pressure and cognitive function in elderly hypertensive patients. J Hum Hypertens 2006; 20: 177-185.
    • (2006) J Hum Hypertens , vol.20 , pp. 177-185
    • Fogari, R.1    Mugellini, A.2    Zoppi, A.3    Lazzari, P.4    Destro, M.5    Rinaldi, A.6    Preti, P.7
  • 52
    • 33745993277 scopus 로고    scopus 로고
    • Angiotensin II type-2 receptor stimulation prevents neural damage by transcriptional activation of methyl methanesulfonate sensitive 2
    • DOI 10.1161/01.HYP.0000229648.67883.f9, PII 0000426820060700000026
    • Mogi M, Li JM, Iwanami J, Min LJ, Tsukuda K, Iwai M, Horiuchi M. Angiotensin II type-2 receptor stimulation prevents neural damage by transcriptional activation of methyl methanesulfonate sensitive 2. Hypertension 2006; 48: 141-148. (Pubitemid 44297536)
    • (2006) Hypertension , vol.48 , Issue.1 , pp. 141-148
    • Mogi, M.1    Li, J.-M.2    Iwanami, J.3    Min, L.-J.4    Tsukuda, K.5    Iwai, M.6    Horiuchi, M.7
  • 54
    • 33748937894 scopus 로고    scopus 로고
    • The CNS renin-angiotensin system
    • DOI 10.1007/s00441-006-0190-8
    • von Bohlen und Halbach O, Albrecht D. The CNS renin-angiotensin system. Cell Tissue Res 2006; 326: 599-616. (Pubitemid 44435828)
    • (2006) Cell and Tissue Research , vol.326 , Issue.2 , pp. 599-616
    • Halbach, O.1    Albrecht, D.2
  • 55
    • 50549212658 scopus 로고
    • Clinical characteristics of primary aldosteronism from an analysis of 145 cases
    • Conn JW, Knopf RF, Nesbit RM. Clinical characteristics of primary aldosteronism from an analysis of 145 cases. Am J Surg 1964; 107: 159-172.
    • (1964) Am J Surg , vol.107 , pp. 159-172
    • Conn, J.W.1    Knopf, R.F.2    Nesbit, R.M.3
  • 56
    • 0029007648 scopus 로고
    • Vascular complications in patients with aldosterone producing adenoma in Japan: Comparative study with essential hypertension. The Research Committee of Disorders of Adrenal Hormones in Japan
    • Takeda R, Matsubara T, Miyamori I, Hatakeyama H, Morise T. Vascular complications in patients with aldosterone producing adenoma in Japan: comparative study with essential hypertension. The Research Committee of Disorders of Adrenal Hormones in Japan. J Endocrinol Invest 1995; 18: 370-373.
    • (1995) J Endocrinol Invest , vol.18 , pp. 370-373
    • Takeda, R.1    Matsubara, T.2    Miyamori, I.3    Hatakeyama, H.4    Morise, T.5
  • 57
    • 0030864577 scopus 로고    scopus 로고
    • The role of blood pressure and aldosterone in the production of hemorrhagic stroke in captopril-treated hypertensive rats
    • discussion 1829
    • MacLeod AB, Vasdev S, Smeda JS. The role of blood pressure and aldosterone in the production of hemorrhagic stroke in captopril-treated hypertensive rats. Stroke 1997; 28: 1821-1828; discussion 1829.
    • (1997) Stroke , vol.28 , pp. 1821-1828
    • MacLeod, A.B.1    Vasdev, S.2    Smeda, J.S.3
  • 58
    • 0035458773 scopus 로고    scopus 로고
    • Pathophysiological effects of aldosterone in cardiovascular tissues
    • PII S1043276001004325
    • Rocha R, Stier CT Jr. Pathophysiological effects of aldosterone in cardiovascular tissues. Trends Endocrinol Metab 2001; 12: 308-314. (Pubitemid 33714222)
    • (2001) Trends in Endocrinology and Metabolism , vol.12 , Issue.7 , pp. 308-314
    • Rocha, R.1    Stier Jr., C.T.2
  • 64
    • 55449084867 scopus 로고    scopus 로고
    • Resin-angiotensin system in the brain as a new target of antihypertensive therapy
    • Ito S, Komatsu K, Yajima Y, Hirayama A. Resin-angiotensin system in the brain as a new target of antihypertensive therapy. Hypertens Res 2008; 31: 1487-1488.
    • (2008) Hypertens Res , vol.31 , pp. 1487-1488
    • Ito, S.1    Komatsu, K.2    Yajima, Y.3    Hirayama, A.4
  • 66
    • 0042233718 scopus 로고    scopus 로고
    • Inhibiting angiotensin receptors in the brain: Possible therapeutic implications
    • DOI 10.1185/030079903125001974
    • Unger T. Inhibiting angiotensin receptors in the brain: possible therapeutic implications. Curr Med Res Opin 2003; 19: 449-451. (Pubitemid 36994451)
    • (2003) Current Medical Research and Opinion , vol.19 , Issue.5 , pp. 449-451
    • Unger, T.1
  • 67
    • 18244403127 scopus 로고    scopus 로고
    • Critical role of angiotensin II in excess salt-induced brain oxidative stress of stroke-prone spontaneously hypertensive rats
    • Kim-Mitsuyama S, Yamamoto E, Tanaka T, Zhan Y, Izumi Y, Izumiya Y, Ioroi T, Wanibuchi H, Iwao H. Critical role of angiotensin II in excess salt-induced brain oxidative stress of stroke-prone spontaneously hypertensive rats. Stroke 2005; 36: 1083-1088.
    • (2005) Stroke , vol.36 , pp. 1083-1088
    • Kim-Mitsuyama, S.1    Yamamoto, E.2    Tanaka, T.3    Zhan, Y.4    Izumi, Y.5    Izumiya, Y.6    Ioroi, T.7    Wanibuchi, H.8    Iwao, H.9
  • 68
    • 0037534905 scopus 로고    scopus 로고
    • The study on cognition and prognosis in the elderly (SCOPE): Principal results of a randomized double-blind intervention trial
    • DOI 10.1097/00004872-200305000-00011
    • Lithell H, Hansson L, Skoog I, Elmfeldt D, Hofman A, Olofsson B, Trenkwalder P, Zanchetti A. The Study on Cognition and Prognosis in the Elderly (SCOPE): principal results of a randomized double-blind intervention trial. J Hypertens 2003; 21: 875-886. (Pubitemid 36677151)
    • (2003) Journal of Hypertension , vol.21 , Issue.5 , pp. 875-886
    • Lithell, H.1    Hansson, L.2    Skoog, I.3    Elmfeldt, D.4    Hofman, A.5    Olofsson, B.6    Trenkwalder, P.7    Zanchetti, A.8
  • 69
    • 23744468024 scopus 로고    scopus 로고
    • Effect of baseline cognitive function and antihypertensive treatment on cognitive and cardiovascular outcomes: Study on COgnition and Prognosis in the Elderly (SCOPE)
    • DOI 10.1016/j.amjhyper.2005.02.013, PII S0895706105001020
    • Skoog I, Lithell H, Hansson L, Elmfeldt D, Hofman A, Olofsson B, Trenkwalder P, Zanchetti A. Effect of baseline cognitive function and antihypertensive treatment on cognitive and cardiovascular outcomes: Study on COgnition and Prognosis in the Elderly (SCOPE). Am J Hypertens 2005; 18: 1052-1059. (Pubitemid 41139903)
    • (2005) American Journal of Hypertension , vol.18 , Issue.8 , pp. 1052-1059
    • Skoog, I.1    Lithell, H.2    Hansson, L.3    Elmfeldt, D.4    Hofman, A.5    Olofsson, B.6    Trenkwalder, P.7    Zanchetti, A.8
  • 70
    • 43249112025 scopus 로고    scopus 로고
    • Candesartan and cognitive decline in older patients with hypertension: A substudy of the SCOPE trial
    • DOI 10.1212/01.wnl.0000311447.85948.78, PII 0000611420080506100019
    • Saxby BK, Harrington F, Wesnes KA, McKeith IG, Ford GA. Candesartan and cognitive decline in older patients with hypertension: a substudy of the SCOPE trial. Neurology 2008; 70 (19 Pt 2), 1858-1866. (Pubitemid 351653953)
    • (2008) Neurology , vol.70 , Issue.19 PART 2 , pp. 1858-1866
    • Saxby, B.K.1    Harrington, F.2    Wesnes, K.A.3    McKeith, I.G.4    Ford, G.A.5
  • 71
    • 1542616497 scopus 로고    scopus 로고
    • Effects of valsartan compared with enalapril on blood pressure and cognitive function in elderly patients with essential hypertension
    • DOI 10.1007/s00228-003-0717-9
    • Fogari R, Mugellini A, Zoppi A, Marasi G, Pasotti C, Poletti L, Rinaldi A, Preti P. Effects of valsartan compared with enalapril on blood pressure and cognitive function in elderly patients with essential hypertension. Eur J Clin Pharmacol 2004; 59: 863-868. (Pubitemid 38333676)
    • (2004) European Journal of Clinical Pharmacology , vol.59 , Issue.12 , pp. 863-868
    • Fogari, R.1    Mugellini, A.2    Zoppi, A.3    Marasi, G.4    Pasotti, C.5    Poletti, L.6    Rinaldi, A.7    Preti, P.8
  • 73
    • 84867866631 scopus 로고    scopus 로고
    • Brain penetration of telmisartan, a unique centrally acting angiotensin II type 1 receptor blocker, studied by PET in conscious rhesus macaques
    • Noda A, Fushiki H, Murakami Y, Sasaki H, Miyoshi S, Kakuta H, Nishimura S. Brain penetration of telmisartan, a unique centrally acting angiotensin II type 1 receptor blocker, studied by PET in conscious rhesus macaques. Nucl Med Biol 2012; 39: 1232-1235.
    • (2012) Nucl Med Biol , vol.39 , pp. 1232-1235
    • Noda, A.1    Fushiki, H.2    Murakami, Y.3    Sasaki, H.4    Miyoshi, S.5    Kakuta, H.6    Nishimura, S.7
  • 74
    • 84869086473 scopus 로고    scopus 로고
    • Telmisartan protects against cognitive decline via up-regulation of brain-derived neurotrophic factor/tropomyosin-related kinase B in hippocampus of hypertensive rats
    • Kishi T, Hirooka Y, Sunagawa K. Telmisartan protects against cognitive decline via up-regulation of brain-derived neurotrophic factor/tropomyosin- related kinase B in hippocampus of hypertensive rats. J Cardiol 2012; 60: 489-494.
    • (2012) J Cardiol , vol.60 , pp. 489-494
    • Kishi, T.1    Hirooka, Y.2    Sunagawa, K.3
  • 75
    • 84860224428 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma activation with angiotensin II type 1 receptor blockade is pivotal for the prevention of blood-brain barrier impairment and cognitive decline in type 2 diabetic mice
    • Min LJ, Mogi M, Shudou M, Jing F, Tsukuda K, Ohshima K, Iwanami J, Horiuchi M. Peroxisome proliferator-activated receptor-gamma activation with angiotensin II type 1 receptor blockade is pivotal for the prevention of blood-brain barrier impairment and cognitive decline in type 2 diabetic mice. Hypertension 2012; 59: 1079-1088.
    • (2012) Hypertension , vol.59 , pp. 1079-1088
    • Min, L.J.1    Mogi, M.2    Shudou, M.3    Jing, F.4    Tsukuda, K.5    Ohshima, K.6    Iwanami, J.7    Horiuchi, M.8
  • 76
    • 84859006978 scopus 로고    scopus 로고
    • Effects of telmisartan on cognition and regional cerebral blood flow in hypertensive patients with Alzheimer's disease
    • Kume K, Hanyu H, Sakurai H, Takada Y, Onuma T, Iwamoto T. Effects of telmisartan on cognition and regional cerebral blood flow in hypertensive patients with Alzheimer's disease. Geriatr Gerontol Int 2012; 12: 207-214.
    • (2012) Geriatr Gerontol Int , vol.12 , pp. 207-214
    • Kume, K.1    Hanyu, H.2    Sakurai, H.3    Takada, Y.4    Onuma, T.5    Iwamoto, T.6
  • 77
    • 70450200272 scopus 로고    scopus 로고
    • Effect of the angiotensin II type 1 receptor antagonist olmesartan on cerebral hemodynamics and rehabilitation outcomes in hypertensive post-stroke patients
    • Matsumoto S, Shimodozono M, Miyata R, Kawahira K. Effect of the angiotensin II type 1 receptor antagonist olmesartan on cerebral hemodynamics and rehabilitation outcomes in hypertensive post-stroke patients. Brain Inj 2009; 23: 1065-1072.
    • (2009) Brain Inj , vol.23 , pp. 1065-1072
    • Matsumoto, S.1    Shimodozono, M.2    Miyata, R.3    Kawahira, K.4
  • 78
    • 0026736180 scopus 로고
    • Losartan potassium, a nonpeptide antagonist of angiotensin II, chronically administered P.O. Does not readily cross the blood-brain barrier
    • Bui JD, Kimura B, Phillips MI. Losartan potassium, a nonpeptide antagonist of angiotensin II, chronically administered p.o. does not readily cross the blood-brain barrier. Eur J Pharmacol 1992; 219: 147-151.
    • (1992) Eur J Pharmacol , vol.219 , pp. 147-151
    • Bui, J.D.1    Kimura, B.2    Phillips, M.I.3
  • 79
    • 0027287871 scopus 로고
    • Binding of angiotensin antagonists to rat liver and brain membranes measured ex vivo
    • Marshall FH, Clark SA, Michel AD, Barnes JC. Binding of angiotensin antagonists to rat liver and brain membranes measured ex vivo. Br J Pharmacol 1993; 109: 760-764. (Pubitemid 23181058)
    • (1993) British Journal of Pharmacology , vol.109 , Issue.3 , pp. 760-764
    • Marshall, F.H.1    Clark, S.A.2    Michel, A.D.3    Barnes, J.C.4
  • 80
    • 0035028739 scopus 로고    scopus 로고
    • Comparative studies on the memory-enhancing actions of captopril and losartan in mice using inhibitory shock avoidance paradigm
    • DOI 10.1054/npep.2000.0845
    • Raghavendra V, Chopra K, Kulkarni SK. Comparative studies on the memory-enhancing actions of captopril and losartan in mice using inhibitory shock avoidance paradigm. Neuropeptides 2001; 35: 65-69. (Pubitemid 32382318)
    • (2001) Neuropeptides , vol.35 , Issue.1 , pp. 65-69
    • Raghavendra, V.1    Chopra, K.2    Kulkarni, S.K.3
  • 84
    • 0031827616 scopus 로고    scopus 로고
    • Evaluation of the ability of irbesartan to cross the blood-brain barrier following acute intragastric treatment
    • DOI 10.1016/S0014-2999(98)00329-X, PII S001429999800329X
    • Polidori C, Ciccocioppo R, Nisato D, Cazaubon C, Massi M. Evaluation of the ability of irbesartan to cross the blood-brain barrier following acute intragastric treatment. Eur J Pharmacol 1998; 352: 15-21. (Pubitemid 28359402)
    • (1998) European Journal of Pharmacology , vol.352 , Issue.1 , pp. 15-21
    • Polidori, C.1    Ciccocioppo, R.2    Nisato, D.3    Cazaubon, C.4    Massi, M.5
  • 85
    • 14744287778 scopus 로고    scopus 로고
    • Inhibition of brain angiotensin-converting enzyme by peripheral administration of trandolapril versus lisinopril in Wistar rats
    • DOI 10.1016/j.amjhyper.2004.09.004
    • Tan J, Wang JM, Leenen FH. Inhibition of brain angiotensin-converting enzyme by peripheral administration of trandolapril versus lisinopril in Wistar rats. Am J Hypertens 2005; 18 (2 Pt 1), 158-164. (Pubitemid 40332543)
    • (2005) American Journal of Hypertension , vol.18 , Issue.2 , pp. 158-164
    • Tan, J.1    Wang, J.M.2    Leenen, F.H.H.3
  • 87
    • 80055005001 scopus 로고    scopus 로고
    • Effect of a centrally active angiotensin converting enzyme inhibitor, perindopril, on cognitive performance in chronic cerebral hypo-perfusion rats
    • Yamada K, Horita T, Takayama M, Takahashi S, Takaba K, Nagata Y, Suzuki N, Kanda T. Effect of a centrally active angiotensin converting enzyme inhibitor, perindopril, on cognitive performance in chronic cerebral hypo-perfusion rats. Brain Res1421: 110-120.
    • Brain Res , vol.1421 , pp. 110-120
    • Yamada, K.1    Horita, T.2    Takayama, M.3    Takahashi, S.4    Takaba, K.5    Nagata, Y.6    Suzuki, N.7    Kanda, T.8
  • 89
    • 13544250575 scopus 로고    scopus 로고
    • Use of angiotensin-converting enzyme inhibitors and variations in cognitive performance among patients with heart failure
    • DOI 10.1093/eurheartj/ehi058
    • Zuccala G, Onder G, Marzetti E, Lo Monaco MR, Cesari M, Cocchi A, Carbonin P, Bernabei R, Grp GS. Use of angiotensin-converting enzyme inhibitors and variations in cognitive performance among patients with heart failure. Eur Heart J 2005; 26: 226-233. (Pubitemid 40222360)
    • (2005) European Heart Journal , vol.26 , Issue.3 , pp. 226-233
    • Zuccala, G.1    Onder, G.2    Marzetti, E.3    Lo Monaco, M.R.4    Cesari, M.5    Cocchi, A.6    Carbonin, P.7    Bernabei, R.8
  • 91
    • 0028154884 scopus 로고
    • Effects of cilazapril and nitrendipine on blood pressure, mood, sleep, and cognitive function in elderly hypertensive patients: An Italian multicenter study
    • DOI 10.1097/00005344-199400243-00012
    • Leonetti G, Salvetti A. Effects of cilazapril and nitrendipine on blood pressure, mood, sleep, and cognitive function in elderly hypertensive patients: an Italian multicenter study. J Cardiovasc Pharmacol 1994; 24(Suppl3): S73-S77. (Pubitemid 24361313)
    • (1994) Journal of Cardiovascular Pharmacology , vol.24 , Issue.SUPPL. 3
    • Leonetti, G.1    Salvetti, A.2


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