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Volumn 10, Issue 9, 2013, Pages 529-536

Caveola-forming proteins caveolin-1 and PTRF in prostate cancer

Author keywords

[No Author keywords available]

Indexed keywords

CAVEOLIN 1; COLLAGEN; GELATINASE B; POLYMERASE I AND TRANSCRIPT RELEASE FACTOR; TUMOR MARKER; UNCLASSIFIED DRUG;

EID: 84883740020     PISSN: 17594812     EISSN: 17594820     Source Type: Journal    
DOI: 10.1038/nrurol.2013.168     Document Type: Review
Times cited : (48)

References (126)
  • 1
    • 84872959202 scopus 로고    scopus 로고
    • Caveolae as plasma membrane sensors, protectors and organizers
    • Parton, R. G. & del Pozo, M. A. Caveolae as plasma membrane sensors, protectors and organizers. Nat. Rev. Mol. Cell Biol. 14, 98-112 (2013).
    • (2013) Nat. Rev. Mol. Cell Biol. , vol.14 , pp. 98-112
    • Parton, R.G.1    Del Pozo, M.A.2
  • 3
    • 84855236312 scopus 로고    scopus 로고
    • Short-term stromal alterations in the rat ventral prostate following alloxan-induced diabetes and the influence of insulin replacement
    • Gobbo, M. G., Taboga, S. R., Ribeiro, D. L. & Goes, R. M. Short-term stromal alterations in the rat ventral prostate following alloxan-induced diabetes and the influence of insulin replacement. Micron 43, 326-333 (2012).
    • (2012) Micron , vol.43 , pp. 326-333
    • Gobbo, M.G.1    Taboga, S.R.2    Ribeiro, D.L.3    Goes, R.M.4
  • 4
    • 0036992806 scopus 로고    scopus 로고
    • Dedifferentiation of stromal smooth muscle as a factor in prostate carcinogenesis
    • Wong, Y. C. & Tam, N. N. C. Dedifferentiation of stromal smooth muscle as a factor in prostate carcinogenesis. Differentiation 70, 633-645 (2002).
    • (2002) Differentiation , vol.70 , pp. 633-645
    • Wong, Y.C.1    Tam, N.N.C.2
  • 5
    • 33845892493 scopus 로고    scopus 로고
    • Ultrastructural changes in prostate cells during hormone-induced canine prostatic hyperplasia
    • Gallardo-Arrieta, F. et al. Ultrastructural changes in prostate cells during hormone-induced canine prostatic hyperplasia. Ultrastruct. Pathol. 30, 435-442 (2006).
    • (2006) Ultrastruct. Pathol. , vol.30 , pp. 435-442
    • Gallardo-Arrieta, F.1
  • 6
    • 77958474331 scopus 로고    scopus 로고
    • Changes in caveolae, caveolin, and polymerase 1 and transcript release factor (PTRF) expression in prostate cancer progression
    • Gould, M. L., Williams, G. & Nicholson, H. D. Changes in caveolae, caveolin, and polymerase 1 and transcript release factor (PTRF) expression in prostate cancer progression. Prostate 70, 1609-1621 (2010).
    • (2010) Prostate , vol.70 , pp. 1609-1621
    • Gould, M.L.1    Williams, G.2    Nicholson, H.D.3
  • 7
    • 0035851197 scopus 로고    scopus 로고
    • Caveolin-1 null mice are viable but show evidence of hyperproliferative and vascular abnormalities
    • Razani, B. et al. Caveolin-1 null mice are viable but show evidence of hyperproliferative and vascular abnormalities. J. Biol. Chem. 276, 38121-38138 (2001).
    • (2001) J. Biol. Chem. , vol.276 , pp. 38121-38138
    • Razani, B.1
  • 8
    • 0037143769 scopus 로고    scopus 로고
    • Defects in caveolin-1 cause dilated cardiomyopathy and pulmonary hypertension in knockout mice
    • Zhao, Y. Y. et al. Defects in caveolin-1 cause dilated cardiomyopathy and pulmonary hypertension in knockout mice. Proc. Natl Acad. Sci. USA 99, 11375-11380 (2002).
    • (2002) Proc. Natl Acad. Sci. USA , vol.99 , pp. 11375-11380
    • Zhao, Y.Y.1
  • 9
    • 0035964954 scopus 로고    scopus 로고
    • Loss of caveolae, vascular dysfunction, and pulmonary defects in caveolin-1 gene-disrupted mice
    • Drab, M. et al. Loss of caveolae, vascular dysfunction, and pulmonary defects in caveolin-1 gene-disrupted mice. Science 293, 2449-2452 (2001).
    • (2001) Science , vol.293 , pp. 2449-2452
    • Drab, M.1
  • 10
    • 0037131313 scopus 로고    scopus 로고
    • Microvascular hyperpermeability in caveolin-1 (-/-) knock-out mice Treatment with a specific nitric-oxide synthase inhibitor, L-name, restores normal microvascular permeability in Cav-1 null mice
    • Schubert, W. et al. Microvascular hyperpermeability in caveolin-1 (-/-) knock-out mice. Treatment with a specific nitric-oxide synthase inhibitor, L-name, restores normal microvascular permeability in Cav-1 null mice. J. Biol. Chem. 277, 40091-40098 (2002).
    • (2002) J. Biol. Chem. , Issue.277 , pp. 40091-40098
    • Schubert, W.1
  • 11
    • 9144229688 scopus 로고    scopus 로고
    • Caveolin-1 null (-/-) mice show dramatic reductions in life span
    • Park, D. S. et al. Caveolin-1 null (-/-) mice show dramatic reductions in life span. Biochemistry 42, 15124-15131 (2003).
    • (2003) Biochemistry , vol.42 , pp. 15124-15131
    • Park, D.S.1
  • 12
    • 0037303007 scopus 로고    scopus 로고
    • Caveolin-1 null mice develop cardiac hypertrophy with hyperactivation of p42/44 MAP kinase in cardiac fibroblasts
    • Cohen, A. W. et al. Caveolin-1 null mice develop cardiac hypertrophy with hyperactivation of p42/44 MAP kinase in cardiac fibroblasts. Am. J. Physiol. Cell Physiol. 284, C457-C474 (2003).
    • (2003) Am. J. Physiol. Cell Physiol. , vol.284
    • Cohen, A.W.1
  • 13
    • 29644433075 scopus 로고    scopus 로고
    • Disruption of caveolin-1 leads to enhanced nitrosative stress and severe systolic and diastolic heart failure
    • Wunderlich, C. et al. Disruption of caveolin-1 leads to enhanced nitrosative stress and severe systolic and diastolic heart failure. Biochem. Biophys. Res. Commun. 340, 702-708 (2006).
    • (2006) Biochem. Biophys. Res. Commun. , vol.340 , pp. 702-708
    • Wunderlich, C.1
  • 14
    • 34548457220 scopus 로고    scopus 로고
    • Arterial remodeling and plasma volume expansion in caveolin-1-deficient mice
    • Albinsson, S. et al. Arterial remodeling and plasma volume expansion in caveolin-1-deficient mice. Am. J. Physiol. Regul. Integr. Comp. Physiol. 293, R1222-R1231 (2007).
    • (2007) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.293
    • Albinsson, S.1
  • 15
    • 3142579790 scopus 로고    scopus 로고
    • Caveolin-1 deficiency stimulates neointima formation during vascular injury
    • Hassan, G. S., Jasmin, J. F., Schubert, W., Frank, P. G. & Lisanti, M. P. Caveolin-1 deficiency stimulates neointima formation during vascular injury. Biochemistry 43, 8312-8321 (2004).
    • (2004) Biochemistry , vol.43 , pp. 8312-8321
    • Hassan, G.S.1    Jasmin, J.F.2    Schubert, W.3    Frank, P.G.4    Lisanti, M.P.5
  • 16
    • 33748426207 scopus 로고    scopus 로고
    • Transvascular protein transport in mice lacking endothelial caveolae
    • Rosengren, B. I. et al. Transvascular protein transport in mice lacking endothelial caveolae. Am. J. Physiol. Heart Circ. Physiol. 291, H1371-H1377 (2006).
    • (2006) Am. J. Physiol. Heart Circ. Physiol. , vol.291
    • Rosengren, B.I.1
  • 17
    • 33646422239 scopus 로고    scopus 로고
    • Direct evidence for the role of caveolin-1 and caveolae in mechanotransduction and remodeling of blood vessels
    • Yu, J. et al. Direct evidence for the role of caveolin-1 and caveolae in mechanotransduction and remodeling of blood vessels. J. Clin. Invest. 116, 1284-1291 (2006).
    • (2006) J. Clin. Invest. , vol.116 , pp. 1284-1291
    • Yu, J.1
  • 18
    • 0037040994 scopus 로고    scopus 로고
    • Caveolin-1-deficient mice are lean, resistant to diet-induced obesity, and show hypertriglyceridemia with adipocyte abnormalities
    • Razani, B. et al. Caveolin-1-deficient mice are lean, resistant to diet-induced obesity, and show hypertriglyceridemia with adipocyte abnormalities. J. Biol. Chem. 277, 8635-8647 (2002).
    • (2002) J. Biol. Chem. , vol.277 , pp. 8635-8647
    • Razani, B.1
  • 19
    • 0037663884 scopus 로고    scopus 로고
    • Caveolin-1-deficient mice show insulin resistance and defective insulin receptor protein expression in adipose tissue
    • Cohen, A. W. et al. Caveolin-1-deficient mice show insulin resistance and defective insulin receptor protein expression in adipose tissue. Am. J. Physiol. Cell Physiol. 285, C222-C235 (2003).
    • (2003) Am. J. Physiol. Cell Physiol. , vol.285
    • Cohen, A.W.1
  • 20
    • 33748773325 scopus 로고    scopus 로고
    • Caveolin-1 is essential for liver regeneration
    • Fernandez, M. A. et al. Caveolin-1 is essential for liver regeneration. Science 313, 1628-1632 (2006).
    • (2006) Science , vol.313 , pp. 1628-1632
    • Fernandez, M.A.1
  • 22
    • 53049091996 scopus 로고    scopus 로고
    • Deletion of cavin/PTRF causes global loss of caveolae, dyslipidemia, and glucose intolerance
    • Liu, L. et al. Deletion of cavin/PTRF causes global loss of caveolae, dyslipidemia, and glucose intolerance. Cell Metab. 8, 310-317 (2008).
    • (2008) Cell Metab. , vol.8 , pp. 310-317
    • Liu, L.1
  • 23
    • 0037378555 scopus 로고    scopus 로고
    • Disruption of the caveolin-1 gene impairs renal calcium reabsorption and leads to hypercalciuria and urolithiasis
    • Cao, G. et al. Disruption of the caveolin-1 gene impairs renal calcium reabsorption and leads to hypercalciuria and urolithiasis. Am. J. Pathol. 162, 1241-1248 (2003).
    • (2003) Am. J. Pathol. , vol.162 , pp. 1241-1248
    • Cao, G.1
  • 24
    • 9144225357 scopus 로고    scopus 로고
    • Urogenital alterations in aged male caveolin-1 knockout mice
    • Woodman, S. E. et al. Urogenital alterations in aged male caveolin-1 knockout mice. J. Urol. 171, 950-957 (2004).
    • (2004) J. Urol. , vol.171 , pp. 950-957
    • Woodman, S.E.1
  • 25
    • 29144505268 scopus 로고    scopus 로고
    • Getting rid of caveolins: Phenotypes of caveolin-deficient animals
    • Le Lay, S. & Kurzchalia, T. V. Getting rid of caveolins: Phenotypes of caveolin-deficient animals. Biochim. Biophys. Acta 1746, 322-333 (2005).
    • (2005) Biochim. Biophys. Acta , vol.1746 , pp. 322-333
    • Le Lay, S.1    Kurzchalia, T.V.2
  • 26
    • 79551494259 scopus 로고    scopus 로고
    • Biomechanical properties and innervation of the female caveolin-1-deficient detrusor
    • Sadegh, M. K. et al. Biomechanical properties and innervation of the female caveolin-1-deficient detrusor. Br. J. Pharmacol. 162, 1156-1170 (2011).
    • (2011) Br. J. Pharmacol. , vol.162 , pp. 1156-1170
    • Sadegh, M.K.1
  • 27
    • 84864285796 scopus 로고    scopus 로고
    • Impaired contractility and detrusor hypertrophy in cavin-1-deficient mice
    • Karbalaei, M. S. et al. Impaired contractility and detrusor hypertrophy in cavin-1-deficient mice. Eur. J. Pharmacol. 689, 179-185 (2012).
    • (2012) Eur. J. Pharmacol. , vol.689 , pp. 179-185
    • Karbalaei, M.S.1
  • 28
    • 76949095336 scopus 로고    scopus 로고
    • The role of caveolin-1 in prostate cancer: Clinical implications
    • Thompson, T. C. et al. The role of caveolin-1 in prostate cancer: Clinical implications. Prostate Cancer Prostatic Dis. 13, 6-11 (2010).
    • (2010) Prostate Cancer Prostatic Dis. , vol.13 , pp. 6-11
    • Thompson, T.C.1
  • 29
    • 37649011760 scopus 로고    scopus 로고
    • PTRF-cavin, a conserved cytoplasmic protein required for caveola formation and function
    • Hill, M. M. et al. PTRF-cavin, a conserved cytoplasmic protein required for caveola formation and function. Cell 132, 113-124 (2008).
    • (2008) Cell , vol.132 , pp. 113-124
    • Hill, M.M.1
  • 30
    • 84863011674 scopus 로고    scopus 로고
    • Expression of PTRF in PC-3 cells modulates cholesterol dynamics and the actin cytoskeleton impacting secretion pathways
    • M111.012245
    • Inder, K. L. et al. Expression of PTRF in PC-3 cells modulates cholesterol dynamics and the actin cytoskeleton impacting secretion pathways. Mol. Cell. Proteomics 11, M111.012245 (2011).
    • (2011) Mol. Cell. Proteomics , vol.11
    • Inder, K.L.1
  • 31
    • 79151475087 scopus 로고    scopus 로고
    • PTRF-cavin-1 expression decreases the migration of PC3 prostate cancer cells: Role of matrix metalloprotease 9
    • Aung, C. S., Hill, M. M., Bastiani, M., Parton, R. G. & Parat, M. O. PTRF-cavin-1 expression decreases the migration of PC3 prostate cancer cells: Role of matrix metalloprotease 9. Eur. J. Cell Biol. 90, 136-142 (2010).
    • (2010) Eur. J. Cell Biol. , vol.90 , pp. 136-142
    • Aung, C.S.1    Hill, M.M.2    Bastiani, M.3    Parton, R.G.4    Parat, M.O.5
  • 32
    • 84865055662 scopus 로고    scopus 로고
    • Co-regulation of cell polarization and migration by caveolar proteins PTRF/Cavin-1 and caveolin-1
    • Hill, M. M. et al. Co-regulation of cell polarization and migration by caveolar proteins PTRF/Cavin-1 and caveolin-1. PLoS ONE 7, e43041 (2012).
    • (2012) PLoS ONE , vol.7
    • Hill, M.M.1
  • 33
    • 21844454457 scopus 로고    scopus 로고
    • Kinase-regulated quantal assemblies and kiss-and-run recycling of caveolae
    • Pelkmans, L. & Zerial, M. Kinase-regulated quantal assemblies and kiss-and-run recycling of caveolae. Nature 436, 128-133 (2005).
    • (2005) Nature , vol.436 , pp. 128-133
    • Pelkmans, L.1    Zerial, M.2
  • 34
    • 0035877753 scopus 로고    scopus 로고
    • Caveolin-3 null mice show a loss of caveolae, changes in the microdomain distribution of the dystrophin-glycoprotein complex, and t-tubule abnormalities
    • Galbiati, F. et al. Caveolin-3 null mice show a loss of caveolae, changes in the microdomain distribution of the dystrophin-glycoprotein complex, and t-tubule abnormalities. J. Biol. Chem. 276, 21425-21433 (2001).
    • (2001) J. Biol. Chem. , vol.276 , pp. 21425-21433
    • Galbiati, F.1
  • 35
    • 0036123019 scopus 로고    scopus 로고
    • Caveolin-2-deficient mice show evidence of severe pulmonary dysfunction without disruption of caveolae
    • Razani, B. et al. Caveolin-2-deficient mice show evidence of severe pulmonary dysfunction without disruption of caveolae. Mol. Cell. Biol. 22, 2329-2344 (2002).
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 2329-2344
    • Razani, B.1
  • 36
    • 0030941001 scopus 로고    scopus 로고
    • Identification of peptide and protein ligands for the caveolin-scaffolding domain Implications for the interaction of caveolin with caveolae-associated proteins
    • Couet, J., Li, S., Okamoto, T., Ikezu, T. & Lisanti, M. P. Identification of peptide and protein ligands for the caveolin-scaffolding domain. Implications for the interaction of caveolin with caveolae-associated proteins. J. Biol. Chem. 272, 6525-6533 (1997).
    • (1997) J. Biol. Chem. , vol.272 , pp. 6525-6533
    • Couet, J.1    Li, S.2    Okamoto, T.3    Ikezu, T.4    Lisanti, M.P.5
  • 37
    • 0032489443 scopus 로고    scopus 로고
    • Caveolins a family of scaffolding proteins for organizing preassembled signaling complexes at the plasma membrane
    • Okamoto, T., Schlegel, A., Scherer, P. E. & Lisanti, M. P. Caveolins, a family of scaffolding proteins for organizing "preassembled signaling complexes" at the plasma membrane. J. Biol. Chem. 273, 5419-5422 (1998).
    • (1998) J. Biol. Chem. , vol.273 , pp. 5419-5422
    • Okamoto, T.1    Schlegel, A.2    Scherer, P.E.3    Lisanti, M.P.4
  • 38
    • 84866443110 scopus 로고    scopus 로고
    • Evaluating caveolin interactions: Do proteins interact with the caveolin scaffolding domain through a widespread aromatic residue-rich motif?
    • Byrne, D. P., Dart, C. & Rigden, D. J. Evaluating caveolin interactions: Do proteins interact with the caveolin scaffolding domain through a widespread aromatic residue-rich motif? PLoS ONE 7, e44879 (2012).
    • (2012) PLoS ONE , vol.7
    • Byrne, D.P.1    Dart, C.2    Rigden, D.J.3
  • 39
    • 84864025624 scopus 로고    scopus 로고
    • Structure-based reassessment of the caveolin signaling model: Do caveolae regulate signaling through caveolin-protein interactions?
    • Collins, B., Davis, M., Hancock, J. & Parton, R. Structure-based reassessment of the caveolin signaling model: Do caveolae regulate signaling through caveolin-protein interactions? Dev. Cell 23, 11-20 (2012).
    • (2012) Dev. Cell , vol.23 , pp. 11-20
    • Collins, B.1    Davis, M.2    Hancock, J.3    Parton, R.4
  • 40
    • 0024317054 scopus 로고
    • Tyrosine phosphorylation of a 22-kDa protein is correlated with transformation by Rous sarcoma virus
    • Glenney, J. R. Jr. Tyrosine phosphorylation of a 22-kDa protein is correlated with transformation by Rous sarcoma virus. J. Biol. Chem. 264, 20163-20166 (1989).
    • (1989) J. Biol. Chem. , vol.264 , pp. 20163-20166
    • Glenney Jr., J.R.1
  • 41
    • 0035158471 scopus 로고    scopus 로고
    • Caveolin-1 expression negatively regulates cell cycle progression by inducing G (0)/G(1) arrest via a p53/p21(WAF1/Cip1)-dependent mechanism
    • Galbiati, F. et al. Caveolin-1 expression negatively regulates cell cycle progression by inducing G(0)/G(1) arrest via a p53/p21(WAF1/Cip1)-dependent mechanism. Mol. Biol. Cell 12, 2229-2244 (2001).
    • (2001) Mol Biol Cell , vol.12 , pp. 2229-2244
    • Galbiati, F.1
  • 42
    • 0030960332 scopus 로고    scopus 로고
    • Recombinant expression of caveolin-1 in oncogenically transformed cells abrogates anchorage-independent growth
    • Engelman, J. A. et al. Recombinant expression of caveolin-1 in oncogenically transformed cells abrogates anchorage-independent growth. J. Biol. Chem. 272, 16374-16381 (1997).
    • (1997) J. Biol. Chem. , vol.272 , pp. 16374-16381
    • Engelman, J.A.1
  • 43
    • 0038751964 scopus 로고    scopus 로고
    • Absence of caveolin-1 sensitizes mouse skin to carcinogen-induced epidermal hyperplasia and tumor formation
    • Capozza, F. et al. Absence of caveolin-1 sensitizes mouse skin to carcinogen-induced epidermal hyperplasia and tumor formation. Am. J. Pathol. 162, 2029-2039 (2003).
    • (2003) Am. J. Pathol. , vol.162 , pp. 2029-2039
    • Capozza, F.1
  • 44
    • 0037342807 scopus 로고    scopus 로고
    • Loss of caveolin-1 gene expression accelerates the development of dysplastic mammary lesions in tumor-prone transgenic mice
    • Williams, T. M. et al. Loss of caveolin-1 gene expression accelerates the development of dysplastic mammary lesions in tumor-prone transgenic mice. Mol. Biol. Cell 14, 1027-1042 (2003).
    • (2003) Mol. Biol. Cell , vol.14 , pp. 1027-1042
    • Williams, T.M.1
  • 45
    • 19944366937 scopus 로고    scopus 로고
    • Caveolin-1 gene disruption promotes mammary tumorigenesis and dramatically enhances lung metastasis in vivo Role of Cav-1 in cell invasiveness and matrix metalloproteinase (MMP-2/9) secretion
    • Williams, T. M. et al. Caveolin-1 gene disruption promotes mammary tumorigenesis and dramatically enhances lung metastasis in vivo. Role of Cav-1 in cell invasiveness and matrix metalloproteinase (MMP-2/9) secretion. J. Biol. Chem. 279, 51630-51646 (2004).
    • (2004) J. Biol. Chem. , vol.279 , pp. 51630-51646
    • Williams, T.M.1
  • 46
    • 0031758918 scopus 로고    scopus 로고
    • Genes encoding human caveolin-1 and -2 are co-localized to the D7S522 locus (7q31.1), a known fragile site (FRA7G) that is frequently deleted in human cancers
    • Engelman, J. A., Zhang, X. L. & Lisanti, M. P. Genes encoding human caveolin-1 and -2 are co-localized to the D7S522 locus (7q31.1), a known fragile site (FRA7G) that is frequently deleted in human cancers. FEBS Lett. 436, 403-410 (1998).
    • (1998) FEBS Lett. , vol.436 , pp. 403-410
    • Engelman, J.A.1    Zhang, X.L.2    Lisanti, M.P.3
  • 47
    • 33749244775 scopus 로고    scopus 로고
    • Is caveolin-1 a viable therapeutic target to reduce cancer metastasis?
    • van Golen, K. L. Is caveolin-1 a viable therapeutic target to reduce cancer metastasis? Expert Opin. Ther. Targets 10, 709-721 (2006).
    • (2006) Expert Opin. Ther. Targets , vol.10 , pp. 709-721
    • Van Golen, K.L.1
  • 48
    • 52549127487 scopus 로고    scopus 로고
    • Caveolin-1 in tumor progression: The good, the bad and the ugly
    • Goetz, J., Lajoie, P., Wiseman, S. & Nabi, I. Caveolin-1 in tumor progression: The good, the bad and the ugly. Cancer Metastasis Rev. 27, 715-735 (2008).
    • (2008) Cancer Metastasis Rev. , vol.27 , pp. 715-735
    • Goetz, J.1    Lajoie, P.2    Wiseman, S.3    Nabi, I.4
  • 49
    • 38449093572 scopus 로고    scopus 로고
    • The overexpression of caveolin-1 and caveolin-2 correlates with a poor prognosis and tumor progression in esophageal squamous cell carcinoma
    • Ando, T. et al. The overexpression of caveolin-1 and caveolin-2 correlates with a poor prognosis and tumor progression in esophageal squamous cell carcinoma. Oncol. Rep. 18, 601-609 (2007).
    • (2007) Oncol. Rep. , vol.18 , pp. 601-609
    • Ando, T.1
  • 50
    • 11144355393 scopus 로고    scopus 로고
    • Caveolins as tumour markers in lung cancer detected by combined use of cDNA and tissue microarrays
    • Wikman, H. et al. Caveolins as tumour markers in lung cancer detected by combined use of cDNA and tissue microarrays. J. Pathol. 203, 584-593 (2004).
    • (2004) J. Pathol. , vol.203 , pp. 584-593
    • Wikman, H.1
  • 51
    • 85047687155 scopus 로고    scopus 로고
    • Expression of caveolin-1 and caveolin-2 in urothelial carcinoma of the urinary bladder correlates with tumor grade and squamous differentiation
    • Fong, A. et al. Expression of caveolin-1 and caveolin-2 in urothelial carcinoma of the urinary bladder correlates with tumor grade and squamous differentiation. Am. J. Clin. Pathol. 120, 93-100 (2003).
    • (2003) Am. J. Clin. Pathol. , vol.120 , pp. 93-100
    • Fong, A.1
  • 52
    • 33846288318 scopus 로고    scopus 로고
    • Caveolin 1 is overexpressed and amplified in a subset of basal-like and metaplastic breast carcinomas: A morphologic, ultrastructural, immunohistochemical, and in situ hybridization analysis
    • Savage, K. et al. Caveolin 1 is overexpressed and amplified in a subset of basal-like and metaplastic breast carcinomas: A morphologic, ultrastructural, immunohistochemical, and in situ hybridization analysis. Clin. Cancer Res. 13, 90-101 (2007).
    • (2007) Clin. Cancer Res. , vol.13 , pp. 90-101
    • Savage, K.1
  • 53
    • 33645237240 scopus 로고    scopus 로고
    • Overexpression of caveolin-1 and -2 in cell lines and in human samples of inflammatory breast cancer
    • Eynden, G. et al. Overexpression of caveolin-1 and -2 in cell lines and in human samples of inflammatory breast cancer. Breast Cancer Res. Treat. 95, 219-228 (2006).
    • (2006) Breast Cancer Res. Treat. , vol.95 , pp. 219-228
    • Eynden, G.1
  • 54
    • 48149115981 scopus 로고    scopus 로고
    • Caveolin 1 and Caveolin 2 are associated with breast cancer basal-like and triple-negative immunophenotype
    • Elsheikh, S. E. et al. Caveolin 1 and Caveolin 2 are associated with breast cancer basal-like and triple-negative immunophenotype. Br. J. Cancer 99, 327-334 (2008).
    • (2008) Br. J. Cancer , vol.99 , pp. 327-334
    • Elsheikh, S.E.1
  • 55
    • 4644345009 scopus 로고    scopus 로고
    • Clinical significance of caveolin-1 caveolin-2 and her2neu mrna expression in human breast cancer
    • Sagara, Y. et al. Clinical significance of Caveolin-1, Caveolin-2 and HER2/neu mRNA expression in human breast cancer. Br. J. Cancer 91, 959-965 (2004).
    • (2004) Br. J. Cancer , vol.91 , pp. 959-965
    • Sagara, Y.1
  • 56
    • 0031872767 scopus 로고    scopus 로고
    • Elevated expression of caveolin is associated with prostate and breast cancer
    • Yang, G. et al. Elevated expression of caveolin is associated with prostate and breast cancer. Clin. Cancer Res. 4, 1873-1880 (1998).
    • (1998) Clin. Cancer Res. , vol.4 , pp. 1873-1880
    • Yang, G.1
  • 57
    • 0035872436 scopus 로고    scopus 로고
    • Secreted caveolin-1 stimulates cell survival/clonal growth and contributes to metastasis in androgen-insensitive prostate cancer
    • Tahir, S. A. et al. Secreted caveolin-1 stimulates cell survival/clonal growth and contributes to metastasis in androgen-insensitive prostate cancer. Cancer Res. 61, 3882-3885 (2001).
    • (2001) Cancer Res. , vol.61 , pp. 3882-3885
    • Tahir, S.A.1
  • 58
    • 0037369151 scopus 로고    scopus 로고
    • Caveolin-1 expression is a predictor of recurrence-free survival in pT2N0 prostate carcinoma diagnosed in Japanese patients
    • Satoh, T. et al. Caveolin-1 expression is a predictor of recurrence-free survival in pT2N0 prostate carcinoma diagnosed in Japanese patients. Cancer 97, 1225-1233 (2003).
    • (2003) Cancer , vol.97 , pp. 1225-1233
    • Satoh, T.1
  • 59
    • 14744275841 scopus 로고    scopus 로고
    • Combined c-Myc and caveolin-1 expression in human prostate carcinoma predicts prostate carcinoma progression
    • Yang, G., Timme, T. L., Frolov, A., Wheeler, T. M. & Thompson, T. C. Combined c-Myc and caveolin-1 expression in human prostate carcinoma predicts prostate carcinoma progression. Cancer 103, 1186-1194 (2005).
    • (2005) Cancer , vol.103 , pp. 1186-1194
    • Yang, G.1    Timme, T.L.2    Frolov, A.3    Wheeler, T.M.4    Thompson, T.C.5
  • 60
    • 84856292514 scopus 로고    scopus 로고
    • Caveolin-1 as a potential high-risk prostate cancer biomarker
    • Gumulec, J. et al. Caveolin-1 as a potential high-risk prostate cancer biomarker. Oncol. Rep. 27, 831-841 (2012).
    • (2012) Oncol. Rep. , vol.27 , pp. 831-841
    • Gumulec, J.1
  • 61
    • 34247589588 scopus 로고    scopus 로고
    • Caveolin-1 overexpression is associated with aggressive prostate cancer recurrence
    • Karam, J. A. et al. Caveolin-1 overexpression is associated with aggressive prostate cancer recurrence. Prostate 67, 614-622 (2007).
    • (2007) Prostate , vol.67 , pp. 614-622
    • Karam, J.A.1
  • 62
    • 35348900076 scopus 로고    scopus 로고
    • Correlative evidence that prostate cancer cell-derived caveolin-1 mediates angiogenesis
    • Yang, G. et al. Correlative evidence that prostate cancer cell-derived caveolin-1 mediates angiogenesis. Hum. Pathol. 38, 1688-1695 (2007).
    • (2007) Hum. Pathol. , vol.38 , pp. 1688-1695
    • Yang, G.1
  • 63
    • 0033571471 scopus 로고    scopus 로고
    • Caveolin-1 expression in clinically confined human prostate cancer: A novel prognostic marker
    • Yang, G., Truong, L. D., Wheeler, T. M. & Thompson, T. C. Caveolin-1 expression in clinically confined human prostate cancer: A novel prognostic marker. Cancer Res. 59, 5719-5723 (1999).
    • (1999) Cancer Res. , vol.59 , pp. 5719-5723
    • Yang, G.1    Truong, L.D.2    Wheeler, T.M.3    Thompson, T.C.4
  • 64
    • 33748342150 scopus 로고    scopus 로고
    • Preoperative serum caveolin-1 as a prognostic marker for recurrence in a radical prostatectomy cohort
    • Tahir, S. A. et al. Preoperative serum caveolin-1 as a prognostic marker for recurrence in a radical prostatectomy cohort. Clin. Cancer Res. 12, 4872-4875 (2006).
    • (2006) Clin. Cancer Res. , vol.12 , pp. 4872-4875
    • Tahir, S.A.1
  • 65
    • 41749119194 scopus 로고    scopus 로고
    • Expression changes of CAV1 and EZH2, located on 7q31 approximately q36, are rarely related to genomic alterations in primary prostate carcinoma
    • Bachmann, N. et al. Expression changes of CAV1 and EZH2, located on 7q31 approximately q36, are rarely related to genomic alterations in primary prostate carcinoma. Cancer Genet. Cytogenet. 182, 103-110 (2008).
    • (2008) Cancer Genet. Cytogenet. , vol.182 , pp. 103-110
    • Bachmann, N.1
  • 66
    • 84855729427 scopus 로고    scopus 로고
    • Expression of endothelial factors in prostate cancer: A possible role of caveolin-1 for tumour progression
    • Steiner, I., Jung, K., Miller, K., Stephan, C. & Erbersdobler, A. Expression of endothelial factors in prostate cancer: A possible role of caveolin-1 for tumour progression. Oncol. Rep. 27, 389-395 (2012).
    • (2012) Oncol. Rep. , vol.27 , pp. 389-395
    • Steiner, I.1    Jung, K.2    Miller, K.3    Stephan, C.4    Erbersdobler, A.5
  • 67
    • 79953251675 scopus 로고    scopus 로고
    • Significant association of caveolin-1 (CAV1) genotypes with prostate cancer susceptibility in Taiwan
    • Wu, H. C. et al. Significant association of caveolin-1 (CAV1) genotypes with prostate cancer susceptibility in Taiwan. Anticancer Res. 31, 745-749 (2011).
    • (2011) Anticancer Res. , vol.31 , pp. 745-749
    • Wu, H.C.1
  • 68
    • 25444458079 scopus 로고    scopus 로고
    • Association of a CAV-1 haplotype to familial aggressive prostate cancer
    • Haeusler, J. et al. Association of a CAV-1 haplotype to familial aggressive prostate cancer. Prostate 65, 171-177 (2005).
    • (2005) Prostate , vol.65 , pp. 171-177
    • Haeusler, J.1
  • 69
    • 0035130638 scopus 로고    scopus 로고
    • Hypermethylation of the caveolin-1 gene promoter in prostate cancer
    • Cui, J. et al. Hypermethylation of the caveolin-1 gene promoter in prostate cancer. Prostate 46, 249-256 (2001).
    • (2001) Prostate , vol.46 , pp. 249-256
    • Cui, J.1
  • 70
    • 77952896637 scopus 로고    scopus 로고
    • Association of caveolin-1 and -2 genetic variants and post-treatment serum caveolin-1 with prostate cancer risk and outcomes
    • Langeberg, W. J. et al. Association of caveolin-1 and -2 genetic variants and post-treatment serum caveolin-1 with prostate cancer risk and outcomes. Prostate 70, 1020-1035 (2010).
    • (2010) Prostate , vol.70 , pp. 1020-1035
    • Langeberg, W.J.1
  • 71
    • 0035361376 scopus 로고    scopus 로고
    • Caveolin-1 mediates testosterone-stimulated survival/clonal growth and promotes metastatic activities in prostate cancer cells
    • Li, L. et al. Caveolin-1 mediates testosterone-stimulated survival/clonal growth and promotes metastatic activities in prostate cancer cells. Cancer Res. 61, 4386-4392 (2001).
    • (2001) Cancer Res. , vol.61 , pp. 4386-4392
    • Li, L.1
  • 72
    • 0034612591 scopus 로고    scopus 로고
    • Caveolin-1 is regulated by c-myc and suppresses c-myc-induced apoptosis
    • Timme, T. L. et al. Caveolin-1 is regulated by c-myc and suppresses c-myc-induced apoptosis. Oncogene 19, 3256-3265 (2000).
    • (2000) Oncogene , vol.19 , pp. 3256-3265
    • Timme, T.L.1
  • 73
    • 72449146370 scopus 로고    scopus 로고
    • Caveolin-1 promotes autoregulatory Akt-mediated induction of cancer-promoting growth factors in prostate cancer cells
    • Li, L. et al. Caveolin-1 promotes autoregulatory, Akt-mediated induction of cancer-promoting growth factors in prostate cancer cells. Mol. Cancer Res. 7, 1781-1791 (2009).
    • (2009) Mol. Cancer Res. , vol.7 , pp. 1781-1791
    • Li, L.1
  • 74
    • 73949102921 scopus 로고    scopus 로고
    • Caveolin-1 regulates VEGF-stimulated angiogenic activities in prostate cancer and endothelial cells
    • Tahir, S. A., Park, S. & Thompson, T. C. Caveolin-1 regulates VEGF-stimulated angiogenic activities in prostate cancer and endothelial cells. Cancer Biol. Ther. 8, 2286-2296 (2009).
    • (2009) Cancer Biol. Ther. , vol.8 , pp. 2286-2296
    • Tahir, S.A.1    Park, S.2    Thompson, T.C.3
  • 75
    • 0031665843 scopus 로고    scopus 로고
    • Suppression of caveolin expression induces androgen sensitivity in metastatic androgen-insensitive mouse prostate cancer cells
    • Nasu, Y. et al. Suppression of caveolin expression induces androgen sensitivity in metastatic androgen-insensitive mouse prostate cancer cells. Nat. Med. 4, 1062-1064 (1998).
    • (1998) Nat. Med. , vol.4 , pp. 1062-1064
    • Nasu, Y.1
  • 76
    • 21644452110 scopus 로고    scopus 로고
    • Caveolin-1 promotes tumor progression in an autochthonous mouse model of prostate cancer: Genetic ablation of Cav-1 delays advanced prostate tumor development in tramp mice
    • Williams, T. M. et al. Caveolin-1 promotes tumor progression in an autochthonous mouse model of prostate cancer: Genetic ablation of Cav-1 delays advanced prostate tumor development in tramp mice. J. Biol. Chem. 280, 25134-25145 (2005).
    • (2005) J. Biol. Chem. , vol.280 , pp. 25134-25145
    • Williams, T.M.1
  • 77
    • 70349487554 scopus 로고    scopus 로고
    • Functional analysis of secreted caveolin-1 in mouse models of prostate cancer progression
    • Watanabe, M. et al. Functional analysis of secreted caveolin-1 in mouse models of prostate cancer progression. Mol. Cancer Res. 7, 1446-1455 (2009).
    • (2009) Mol. Cancer Res. , vol.7 , pp. 1446-1455
    • Watanabe, M.1
  • 78
    • 38849095886 scopus 로고    scopus 로고
    • Tumor cell-secreted caveolin-1 has proangiogenic activities in prostate cancer
    • Tahir, S. A. et al. Tumor cell-secreted caveolin-1 has proangiogenic activities in prostate cancer. Cancer Res. 68, 731-739 (2008).
    • (2008) Cancer Res. , vol.68 , pp. 731-739
    • Tahir, S.A.1
  • 79
    • 0033203564 scopus 로고    scopus 로고
    • Identification of caveolin-1 in lipoprotein particles secreted by exocrine cells
    • Liu, P., Li, W. P., Machleidt, T. & Anderson, R. G. Identification of caveolin-1 in lipoprotein particles secreted by exocrine cells. Nat. Cell Biol. 1, 369-375 (1999).
    • (1999) Nat. Cell Biol. , vol.1 , pp. 369-375
    • Liu, P.1    Li, W.P.2    Machleidt, T.3    Anderson, R.G.4
  • 80
    • 0035031405 scopus 로고    scopus 로고
    • Cell-specific targeting of caveolin-1 to caveolae, secretory vesicles, cytoplasm or mitochondria
    • Li, W. P., Liu, P., Pilcher, B. K. & Anderson, R. G. Cell-specific targeting of caveolin-1 to caveolae, secretory vesicles, cytoplasm or mitochondria. J. Cell Sci. 114, 1397-1408 (2001).
    • (2001) J. Cell Sci. , vol.114 , pp. 1397-1408
    • Li, W.P.1    Liu, P.2    Pilcher, B.K.3    Anderson, R.G.4
  • 82
    • 37349060696 scopus 로고    scopus 로고
    • Caveolin-1 secreting LNCaP cells induce tumor growth of caveolin-1 negative LNCaP cells in vivo
    • Bartz, R. et al. Caveolin-1 secreting LNCaP cells induce tumor growth of caveolin-1 negative LNCaP cells in vivo. Int. J. Cancer 122, 520-525 (2008).
    • (2008) Int. J. Cancer , vol.122 , pp. 520-525
    • Bartz, R.1
  • 83
    • 33645805450 scopus 로고    scopus 로고
    • Prostasomes-their effects on human male reproduction and fertility
    • Burden, H. P., Holmes, C. H., Persad, R. & Whittington, K. Prostasomes - their effects on human male reproduction and fertility. Hum. Reprod. Update 12, 283-292 (2006).
    • (2006) Hum. Reprod. Update , vol.12 , pp. 283-292
    • Burden, H.P.1    Holmes, C.H.2    Persad, R.3    Whittington, K.4
  • 84
    • 9444253500 scopus 로고    scopus 로고
    • Caveolin-1 and MAL are located on prostasomes secreted by the prostate cancer PC-3 cell line
    • Llorente, A., de Marco, M. C. & Alonso, M. A. Caveolin-1 and MAL are located on prostasomes secreted by the prostate cancer PC-3 cell line. J. Cell Sci. 117, 5343-5351 (2004).
    • (2004) J. Cell Sci. , vol.117 , pp. 5343-5351
    • Llorente, A.1    De Marco, M.C.2    Alonso, M.A.3
  • 85
    • 79957673695 scopus 로고    scopus 로고
    • Multiple recognition assay reveals prostasomes as promising plasma biomarkers for prostate cancer
    • Tavoosidana, G. et al. Multiple recognition assay reveals prostasomes as promising plasma biomarkers for prostate cancer. Proc. Natl Acad. Sci. USA 108, 8809-8814 (2011).
    • (2011) Proc. Natl Acad. Sci. USA , vol.108 , pp. 8809-8814
    • Tavoosidana, G.1
  • 86
    • 77950544231 scopus 로고    scopus 로고
    • Proteomic analysis of prostate cancer metastasis-derived prostasomes
    • Ronquist, K. G., Ronquist, G., Larsson, A. & Carlsson, L. Proteomic analysis of prostate cancer metastasis-derived prostasomes. Anticancer Res. 30, 285-290 (2010).
    • (2010) Anticancer Res. , vol.30 , pp. 285-290
    • Ronquist, K.G.1    Ronquist, G.2    Larsson, A.3    Carlsson, L.4
  • 87
    • 84868208632 scopus 로고    scopus 로고
    • Large oncosomes in human prostate cancer tissues and in the circulation of mice with metastatic disease
    • Di Vizio, D. et al. Large oncosomes in human prostate cancer tissues and in the circulation of mice with metastatic disease. Am. J. Pathol. 181, 1573-1584 (2012).
    • (2012) Am. J. Pathol. , vol.181 , pp. 1573-1584
    • Di Vizio, D.1
  • 88
    • 33744929384 scopus 로고    scopus 로고
    • Stromal antiapoptotic paracrine loop in perineural invasion of prostatic carcinoma
    • Ayala, G. E. et al. Stromal antiapoptotic paracrine loop in perineural invasion of prostatic carcinoma. Cancer Res. 66, 5159-5164 (2006).
    • (2006) Cancer Res. , vol.66 , pp. 5159-5164
    • Ayala, G.E.1
  • 89
    • 84859969455 scopus 로고    scopus 로고
    • Anti-caveolin-1 antibodies as anti-prostate cancer therapeutics
    • Kuo, S. R. et al. Anti-caveolin-1 antibodies as anti-prostate cancer therapeutics. Hybridoma (Larchmt) 31, 77-86 (2012).
    • (2012) Hybridoma (Larchmt) , vol.31 , pp. 77-86
    • Kuo, S.R.1
  • 90
    • 68449103256 scopus 로고    scopus 로고
    • An absence of stromal caveolin-1 is associated with advanced prostate cancer, metastatic disease and epithelial Akt activation
    • Di, V. D. et al. An absence of stromal caveolin-1 is associated with advanced prostate cancer, metastatic disease and epithelial Akt activation. Cell Cycle 8, 2420-2424 (2009).
    • (2009) Cell Cycle , vol.8 , pp. 2420-2424
    • Di, V.D.1
  • 91
    • 84868380040 scopus 로고    scopus 로고
    • The metabolic interactions between tumor cells and tumor-associated stroma (TAS) in prostatic cancer
    • Giatromanolaki, A., Koukourakis, M. I., Koutsopoulos, A., Mendrinos, S. & Sivridis, E. The metabolic interactions between tumor cells and tumor-associated stroma (TAS) in prostatic cancer. Cancer Biol. Ther. 13, 1284-1289 (2012).
    • (2012) Cancer Biol. Ther. , vol.13 , pp. 1284-1289
    • Giatromanolaki, A.1    Koukourakis, M.I.2    Koutsopoulos, A.3    Mendrinos, S.4    Sivridis, E.5
  • 92
    • 84883742376 scopus 로고    scopus 로고
    • PTRF/cavin-1 neutralizes non-caveolar caveolin-1 microdomains in prostate cancer
    • in press
    • Moon, H. PTRF/cavin-1 neutralizes non-caveolar caveolin-1 microdomains in prostate cancer. Oncogene (in press).
    • Oncogene
    • Moon, H.1
  • 93
    • 84857224992 scopus 로고    scopus 로고
    • Caveolin-1 upregulation contributes to c-Myc-induced high-grade prostatic intraepithelial neoplasia and prostate cancer
    • Yang, G. et al. Caveolin-1 upregulation contributes to c-Myc-induced high-grade prostatic intraepithelial neoplasia and prostate cancer. Mol. Cancer Res. 10, 218-229 (2012).
    • (2012) Mol. Cancer Res. , vol.10 , pp. 218-229
    • Yang, G.1
  • 94
    • 12444333159 scopus 로고    scopus 로고
    • Development of an immunoassay for serum caveolin-1: A novel biomarker for prostate cancer
    • Tahir, S. A. et al. Development of an immunoassay for serum caveolin-1: A novel biomarker for prostate cancer. Clin. Cancer Res. 9, 3653-3659 (2003).
    • (2003) Clin. Cancer Res. , Issue.9 , pp. 3653-3659
    • Tahir, S.A.1
  • 95
    • 84873472216 scopus 로고    scopus 로고
    • Serum caveolin-1, a biomarker of drug response and therapeutic target in prostate cancer models
    • Tahir, S. A. et al. Serum caveolin-1, a biomarker of drug response and therapeutic target in prostate cancer models. Cancer Biol. Ther. 14, 117-126 (2013).
    • (2013) Cancer Biol. Ther. , vol.14 , pp. 117-126
    • Tahir, S.A.1
  • 96
    • 67649583182 scopus 로고    scopus 로고
    • MURC/Cavin-4 and cavin family members form tissue-specific caveolar complexes
    • Bastiani, M. et al. MURC/Cavin-4 and cavin family members form tissue-specific caveolar complexes. J. Cell Biol. 185, 1259-1273 (2009).
    • (2009) J. Cell Biol. , vol.185 , pp. 1259-1273
    • Bastiani, M.1
  • 97
    • 42949174820 scopus 로고    scopus 로고
    • A critical role of cavin (PTRF) in caveolae formation and organization
    • Liu, L. & Pilch, P. F. A critical role of cavin (PTRF) in caveolae formation and organization. J. Biol. Chem. 283, 4314-4322 (2008).
    • (2008) J. Biol. Chem. , vol.283 , pp. 4314-4322
    • Liu, L.1    Pilch, P.F.2
  • 98
    • 67650072744 scopus 로고    scopus 로고
    • SDPR induces membrane curvature and functions in the formation of caveolae
    • Hansen, C. G., Bright, N. A., Howard, G. & Nichols, B. J. SDPR induces membrane curvature and functions in the formation of caveolae. Nat. Cell. Biol. 11, 807-814 (2009).
    • (2009) Nat. Cell. Biol. , vol.11 , pp. 807-814
    • Hansen, C.G.1    Bright, N.A.2    Howard, G.3    Nichols, B.J.4
  • 99
    • 67349244346 scopus 로고    scopus 로고
    • SRBC/cavin-3 is a caveolin adapter protein that regulates caveolae function
    • McMahon, K. A. et al. SRBC/cavin-3 is a caveolin adapter protein that regulates caveolae function. EMBO J. 28, 1001-1015 (2009).
    • (2009) EMBO J. , vol.28 , pp. 1001-1015
    • McMahon, K.A.1
  • 100
    • 78649729522 scopus 로고    scopus 로고
    • Caveolae at a glance
    • Bastiani, M. & Parton, R. G. Caveolae at a glance. J. Cell Sci. 123, 3831-3836 (2010).
    • (2010) J. Cell Sci. , vol.123 , pp. 3831-3836
    • Bastiani, M.1    Parton, R.G.2
  • 101
    • 0032696407 scopus 로고    scopus 로고
    • Mechanism of transcription termination: PTRF interacts with the largest subunit of RNA polymerase I and dissociates paused transcription complexes from yeast and mouse
    • Jansa, P. & Grummt, I. Mechanism of transcription termination: PTRF interacts with the largest subunit of RNA polymerase I and dissociates paused transcription complexes from yeast and mouse. Mol. Gen. Genet. 262, 508-514 (1999).
    • (1999) Mol. Gen. Genet. , vol.262 , pp. 508-514
    • Jansa, P.1    Grummt, I.2
  • 102
    • 0032525134 scopus 로고    scopus 로고
    • Cloning and functional characterization of PTRF, a novel protein which induces dissociation of paused ternary transcription complexes
    • Jansa, P., Mason, S. W., Hoffmann-Rohrer, U. & Grummt, I. Cloning and functional characterization of PTRF, a novel protein which induces dissociation of paused ternary transcription complexes. EMBO J. 17, 2855-2864 (1998).
    • (1998) EMBO J. , vol.17 , pp. 2855-2864
    • Jansa, P.1    Mason, S.W.2    Hoffmann-Rohrer, U.3    Grummt, I.4
  • 103
    • 0035863852 scopus 로고    scopus 로고
    • The transcript release factor PTRF augments ribosomal gene transcription by facilitating reinitiation of RNA polymerase I
    • Jansa, P., Burek, C., Sander, E E. & Grummt, I. The transcript release factor PTRF augments ribosomal gene transcription by facilitating reinitiation of RNA polymerase I. Nucleic Acids Res. 29, 423-429 (2001).
    • (2001) Nucleic Acids Res. , vol.29 , pp. 423-429
    • Jansa, P.1    Burek, C.2    Sander, E.E.3    Grummt, I.4
  • 105
    • 80051690151 scopus 로고    scopus 로고
    • Polymerase I and transcript release factor (PTRF)/cavin-1 is a novel regulator of stress-induced premature senescence
    • Volonte, D. & Galbiati, F. Polymerase I and transcript release factor (PTRF)/cavin-1 is a novel regulator of stress-induced premature senescence. J. Biol. Chem. 286, 28657-28661 (2011).
    • (2011) J. Biol. Chem. , vol.286 , pp. 28657-28661
    • Volonte, D.1    Galbiati, F.2
  • 106
    • 79960128557 scopus 로고    scopus 로고
    • Regulation of cellular senescence by the essential caveolar component PTRF/Cavin-1
    • Bai, L. et al. Regulation of cellular senescence by the essential caveolar component PTRF/Cavin-1. Cell Res. 21, 1088-1101 (2011).
    • (2011) Cell Res. , vol.21 , pp. 1088-1101
    • Bai, L.1
  • 107
    • 79953836217 scopus 로고    scopus 로고
    • Polymerase transcriptase release factor (PTRF) anchors MG53 protein to cell injury site for initiation of membrane repair
    • Zhu, H. et al. Polymerase transcriptase release factor (PTRF) anchors MG53 protein to cell injury site for initiation of membrane repair. J. Biol. Chem. 286, 12820-12824 (2011).
    • (2011) J. Biol. Chem. , vol.286 , pp. 12820-12824
    • Zhu, H.1
  • 108
    • 79952383922 scopus 로고    scopus 로고
    • Polymerase I and transcript release factor regulates lipolysis via a phosphorylation-dependent mechanism
    • Aboulaich, N., Chui, P. C., Asara, J. M., Flier, J. S. & Maratos-Flier, E. Polymerase I and transcript release factor regulates lipolysis via a phosphorylation-dependent mechanism. Diabetes 60, 757-765 (2011).
    • (2011) Diabetes , vol.60 , pp. 757-765
    • Aboulaich, N.1    Chui, P.C.2    Asara, J.M.3    Flier, J.S.4    Maratos-Flier, E.5
  • 109
    • 77955285719 scopus 로고    scopus 로고
    • The early nutritional environment of mice determines the capacity for adipose tissue expansion by modulating genes of caveolae structure
    • Kozak, L. P., Newman, S., Chao, P. M., Mendoza, T. & Koza, R. A. The early nutritional environment of mice determines the capacity for adipose tissue expansion by modulating genes of caveolae structure. PLoS ONE 5, e11015 (2010).
    • (2010) PLoS ONE , vol.5
    • Kozak, L.P.1    Newman, S.2    Chao, P.M.3    Mendoza, T.4    Koza, R.A.5
  • 110
    • 70349195987 scopus 로고    scopus 로고
    • Human PTRF mutations cause secondary deficiency of caveolins resulting in muscular dystrophy with generalized lipodystrophy
    • Hayashi, Y. K. et al. Human PTRF mutations cause secondary deficiency of caveolins resulting in muscular dystrophy with generalized lipodystrophy. J. Clin. Invest. 119, 2623-2633 (2009).
    • (2009) J. Clin. Invest. , vol.119 , pp. 2623-2633
    • Hayashi, Y.K.1
  • 111
    • 77950431859 scopus 로고    scopus 로고
    • Fatal cardiac arrhythmia and long-QT syndrome in a new form of congenital generalized lipodystrophy with muscle rippling (CGL4) due to PTRF-CAVIN mutations
    • Rajab, A. et al. Fatal cardiac arrhythmia and long-QT syndrome in a new form of congenital generalized lipodystrophy with muscle rippling (CGL4) due to PTRF-CAVIN mutations. PLoS Genet. 6, e1000874 (2010).
    • (2010) PLoS Genet. , vol.6
    • Rajab, A.1
  • 112
    • 77957244115 scopus 로고    scopus 로고
    • A Japanese child with asymptomatic elevation of serum creatine kinase shows PTRF-CAVIN mutation matching with congenital generalized lipodystrophy type 4
    • Dwianingsih, E. K. et al. A Japanese child with asymptomatic elevation of serum creatine kinase shows PTRF-CAVIN mutation matching with congenital generalized lipodystrophy type 4. Mol. Genet. Metab. 101, 233-237 (2010).
    • (2010) Mol. Genet. Metab. , vol.101 , pp. 233-237
    • Dwianingsih, E.K.1
  • 113
    • 77956097576 scopus 로고    scopus 로고
    • Congenital generalized lipodystrophy type 4 (CGL4) associated with myopathy due to novel PTRF mutations
    • Shastry, S. et al. Congenital generalized lipodystrophy, type 4 (CGL4) associated with myopathy due to novel PTRF mutations. Am. J. Med. Genet. 152A, 2245-2253 (2010).
    • (2010) Am. J. Med. Genet. 152A , pp. 2245-2253
    • Shastry, S.1
  • 114
    • 84862093428 scopus 로고    scopus 로고
    • Two preferentially expressed proteins protect vascular endothelial cells from an attack by peptide-specific CTL
    • Thommen, D. S. et al. Two preferentially expressed proteins protect vascular endothelial cells from an attack by peptide-specific CTL. J. Immunol. 188, 5283-5292 (2012).
    • (2012) J. Immunol. , vol.188 , pp. 5283-5292
    • Thommen, D.S.1
  • 115
    • 52949123622 scopus 로고    scopus 로고
    • Comparisons of tyrosine phosphorylated proteins in cells expressing lung cancer-specific alleles of EGFR and KRAS
    • Guha, U. et al. Comparisons of tyrosine phosphorylated proteins in cells expressing lung cancer-specific alleles of EGFR and KRAS. Proc. Natl Acad. Sci. USA 105, 14112-14117 (2008).
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 14112-14117
    • Guha, U.1
  • 116
    • 84055177023 scopus 로고    scopus 로고
    • Down-regulation of the cavin family proteins in breast cancer
    • Bai, L. et al. Down-regulation of the cavin family proteins in breast cancer. J. Cell. Biochem. 113, 322-328 (2012).
    • (2012) J. Cell. Biochem. , vol.113 , pp. 322-328
    • Bai, L.1
  • 117
    • 84858844311 scopus 로고    scopus 로고
    • PTRF/cavin-1 and MIF proteins are identified as non-small cell lung cancer biomarkers by label-free proteomics
    • Gamez-Pozo, A. et al. PTRF/cavin-1 and MIF proteins are identified as non-small cell lung cancer biomarkers by label-free proteomics. PLoS ONE 7, e33752 (2012).
    • (2012) PLoS ONE , vol.7
    • Gamez-Pozo, A.1
  • 118
    • 33845731701 scopus 로고    scopus 로고
    • Identification and validation of differences in protein levels in normal, premalignant, and malignant lung cells and tissues using high-throughput Western array and immunohistochemistry
    • Shen, J. et al. Identification and validation of differences in protein levels in normal, premalignant, and malignant lung cells and tissues using high-throughput Western array and immunohistochemistry. Cancer Res. 66, 11194-11206 (2006).
    • (2006) Cancer Res. , vol.66 , pp. 11194-11206
    • Shen, J.1
  • 119
    • 84873371589 scopus 로고    scopus 로고
    • PTRF/Cavin-1 is essential for multidrug resistance in cancer cells
    • Yi, J. S. et al. PTRF/Cavin-1 is essential for multidrug resistance in cancer cells. J. Proteome Res. 12, 605-614 (2012).
    • (2012) J. Proteome Res. , vol.12 , pp. 605-614
    • Yi, J.S.1
  • 120
    • 84855688769 scopus 로고    scopus 로고
    • A systems biology approach identifies SART1 as a novel determinant of both 5-fluorouracil and SN38 drug resistance in colorectal cancer
    • Allen, W. L. et al. A systems biology approach identifies SART1 as a novel determinant of both 5-fluorouracil and SN38 drug resistance in colorectal cancer. Mol. Cancer Ther. 11, 119-131 (2012).
    • (2012) Mol. Cancer Ther. , vol.11 , pp. 119-131
    • Allen, W.L.1
  • 121
    • 84869115072 scopus 로고    scopus 로고
    • Phosphocaveolin-1 is a mechanotransducer that induces caveola biogenesis via Egr1 transcriptional regulation
    • Joshi, B. et al. Phosphocaveolin-1 is a mechanotransducer that induces caveola biogenesis via Egr1 transcriptional regulation. J. Cell Biol. 199, 425-435 (2012).
    • (2012) J. Cell Biol. , vol.199 , pp. 425-435
    • Joshi, B.1
  • 122
    • 0032100588 scopus 로고    scopus 로고
    • Expression of early growth response genes in human prostate cancer
    • Eid, M. A., Kumar, M. V., Iczkowski, K. A., Bostwick, D. G. & Tindall, D. J. Expression of early growth response genes in human prostate cancer. Cancer Res. 58, 2461-2468 (1998).
    • (1998) Cancer Res. , vol.58 , pp. 2461-2468
    • Eid, M.A.1    Kumar, M.V.2    Iczkowski, K.A.3    Bostwick, D.G.4    Tindall, D.J.5
  • 123
    • 0034177159 scopus 로고    scopus 로고
    • PTRF (polymerase I and transcript-release factor) is tissue-specific and interacts with the BFCOL1 (binding factor of a type-I collagen promoter) zinc-finger transcription factor which binds to the two mouse type-I collagen gene promoters
    • Hasegawa, T. et al. PTRF (polymerase I and transcript-release factor) is tissue-specific and interacts with the BFCOL1 (binding factor of a type-I collagen promoter) zinc-finger transcription factor which binds to the two mouse type-I collagen gene promoters. Biochem. J. 347, 55-59 (2000).
    • (2000) Biochem. J. , vol.347 , pp. 55-59
    • Hasegawa, T.1
  • 125
    • 1842689994 scopus 로고    scopus 로고
    • Expression of caveolin-1 enhances cholesterol efflux in hepatic cells
    • Fu, Y. et al. Expression of caveolin-1 enhances cholesterol efflux in hepatic cells. J. Biol. Chem. 279, 14140-14146 (2004).
    • (2004) J. Biol. Chem. , vol.279 , pp. 14140-14146
    • Fu, Y.1
  • 126
    • 84873416628 scopus 로고    scopus 로고
    • Dysregulation of cholesterol homeostasis in human prostate cancer through loss of ABCA1
    • Lee, B. H. et al. Dysregulation of cholesterol homeostasis in human prostate cancer through loss of ABCA1. Cancer Res. 73, 1211-1218 (2012).
    • (2012) Cancer Res. , vol.73 , pp. 1211-1218
    • Lee, B.H.1


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