Evaluating Caveolin Interactions: Do Proteins Interact with the Caveolin Scaffolding Domain through a Widespread Aromatic Residue-Rich Motif?

PLoS ONE

Volumn 7, Issue 9, 2012, Pages

  Byrne, Dominic P ^a   Dart, Caroline ^a   Rigden, Daniel J ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CAVEOLIN;

AMINO ACID COMPOSITION; AMINO ACID SEQUENCE; AROMATIC RICH CAVEOLIN BINDING MOTIF; ARTICLE; BINDING SITE; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; RESIDUE ANALYSIS; STRUCTURAL BIOINFORMATICS; STRUCTURE ACTIVITY RELATION;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; AMINO ACIDS, AROMATIC; CAVEOLINS; COMPUTATIONAL BIOLOGY; HUMANS; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEOME; SOLVENTS;

EID: 84866443110     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0044879     Document Type: Article

References (135)

1. Anderson RGW, (1998) The caveolae membrane system. Annu Rev Biochem 67: 199-225.
2. Galbiati F, Razani B, Lisanti MP, (2001) Emerging themes in lipid rafts and caveolae. Cell 106: 403-411.
3. Razani B, Woodman SE, Lisanti MP, (2002) Caveolae: from cell biology to animal physiology. Pharmacol Rev 54: 431-467.
4. Parton RG, Simons K, (2007) The multiple faces of caveolae. Nat Rev Mol Cell Biol 8: 185-194.
5. Patel HH, Murray F, Insel PA, (2008) Caveolae as organizers of pharmacologically relevant signal transduction molecules. Annu Rev Pharmacol Toxicol 48: 359-391.
6. Couet J, Li SW, Okamoto T, Ikezu T, Lisanti MP, (1997) Identification of peptide and protein ligands for the caveolin-scaffolding domain- Implications for the interaction of caveolin with caveolae-associated proteins. J Biol Chem 272: 6525-6533.
7. Okamoto T, Schlegel A, Scherer PE, Lisanti MP, (1998) Caveolins, a family of scaffolding proteins for organizing "preassembled signaling complexes at the plasma membrane". J Biol Chem 273: 5419-5422.
8. Sbaa E, Frerart F, Feron O, (2005) The double regulation of endothelial nitric oxide synthase by caveolae and caveolin: a paradox solved through the study of angiogenesis. Trends Cardiovas Med 15: 157-162.
9. Schilling K, Opitz N, Wiesenthal A, Oess S, Tikkanen R, et al. (2006) Translocation of endothelial nitric-oxide synthase involves a ternary complex with caveolin-1 and NOSTRIN. Mol Biol Cell 17: 3870-3880.
10. Liou JY, Deng WG, Gilroy DW, Shyue SK, Wu KK, (2001) Colocalization and interaction of cyclooxygenase-2 with caveolin-1 in human fibroblasts. J Biol Chem 276: 34975-34982.
11. Bilderback TR, Gazula VR, Lisanti MP, Dobrowsky RT, (1999) Caveolin interacts with Trk A and p75NTR and regulates neurotrophin signaling pathways. J Biol Chem 274: 257-263.
12. Lee H, Volonte D, Galbiati F, Iyengar P, Lublin DM, et al. (2000) Constitutive and growth factor-regulated phosphorylation of caveolin-1 occurs at the same site (Tyr-14) in vivo: Identification of a c-Src/Cav-1/Grb7 signaling cassette. Mol Endocrinol 14: 1750-1775.
13. Panetta D, Biedi C, Repetto S, Cordera R, Maggi D, (2004) IGF-I regulates caveolin 1 and IRS1 interaction in caveolae. Biochem Biophys Res Commun 316: 240-243.
14. Razani B, Lisanti MP, (2001) Two distinct caveolin-1 domains mediate the functional interaction of caveolin-1 with protein kinase A. Am J Phys Cell Physiol. 281: C1241-C1250.
15. Yao Q, Chen J, Cao H, Orth JD, McCaffery JM, et al. (2005) Caveolin-1 interacts directly with dynamin-2. J Mol Biol 348: 491-501.
16. Yamaguchi T, Murata Y, Fujiyoshi Y, Doi T, (2003) Regulated interaction of endothelin B receptor with caveolin-1. Eur J Biochem 270: 1816-1827.
17. Schubert AL, Schubert W, Spray DC, Lisanti MP, (2002) Connexin family members target to lipid raft domains and interact with caveolin-1. Biochemistry 41: 5754-5764.
18. Hagiwara M, Shirai Y, Nomura R, Sasaki M, Kobayashi K, et al. (2009) Caveolin-1 activates Rab5 and enhances endocytosis through direct interaction. Biochem Biophys Res. Commun 378: 73-78.
19. Cabrita MA, Jaggi F, Widjaja SP, Christofori G, (2006) A functional interaction between Sprouty proteins and Caveolin-1. J Biol Chem 281: 29201-29212.
20. Moh MC, Lee LH, Zhang T, Shen S, (2009) Interaction of the immunoglobulin-like cell adhesion molecule hepaCAM with caveolin-1. Biochem Biophys Res Commun. 378: 755-760.
21. Zhang XM, Ling MT, Wang Q, Lau CK, Leung SCL, et al. (2007) Identification of a novel inhibitor of differentiation-1 (ID-1) binding partner, caveolin-1, and its role in epithelial-mesenchymal transition and resistance to apoptosis in prostate cancer cells. J Biol Chem 282: 33284-33294.
22. Gingras D, Gauthier F, Lamy S, Desrosiers RR, Beliveau R, (1998) Localization of RhoA GTPase to endothelial caveolae-enriched membrane domains. Biochem Biophys Res Commun 247: 888-893.
23. Caselli A, Taddei ML, Bini C, Paoli P, Camici G, et al. (2007) Low molecular weight protein tyrosine phosphatase and caveolin-1: Interaction and isoenzyme-dependent regulation. Biochemistry 46: 6383-6392.
24. Neduva V, Linding R, Su-Angrand I, Stark A, de Masi F, et al. (2005) Systematic discovery of new recognition peptides mediating protein interaction networks. PLoS Biol 3: e405.
25. Edwards RJ, Davey NE, Shields DC, (2007) SLiMFinder: A probabilistic method for identifying over-represented, convergently evolved, short linear motifs in proteins. PLoS One 2: e967.
26. Davey NE, Haslam NJ, Shields DC, Edwards RJ, (2010) SLiMFinder: a web server to find novel, significantly over-represented, short protein motifs. Nuc Acids Res 38: W534-W539.
27. Mooney C, Pollastri G, Shields DC, Haslam NJ, (2012) Prediction of short linear protein binding regions. J Mol Biol 415: 193-204.
28. Meszaros B, Simon I, Dosztanyi Z, (2009) Prediction of protein binding regions in disordered proteins. PLoS Comput Biol 5: e1000376.
29. Weatheritt R, Luck K, Petsalaki E, Davey N, Gibson T (2012) The identification of short linear motif-mediated interfaces within the human interactome. Bioinformatics 10.1093/bioinformatics/bts072.
30. Alioua A, Lu R, Kumar Y, Eghbali M, Kundu P, et al. (2008) Slo1 caveolin-binding motif, a mechanism of caveolin-1-Slo1 interaction regulating Slo1 surface expression. J Biol Chem 283: 4808-4817.
31. Chun J, Hyun S, Kwon T, Lee EJ, Hong SK, et al. (2005) The subcellular localization control of integrin linked kinase 1 through its protein-protein interaction with caveolin-1. Cell Signal 17: 751-760.
32. Santibanez JF, Blanco FJ, Garrido-Martin EM, Sanz-Rodriguez F, del Pozo MA, et al. (2008) Caveolin-1 interacts and cooperates with the transforming growth factor-beta type I receptor ALK1 in endothelial caveolae. Cardiovasc Res 77: 791-799.
33. Kong MMC, Hasbi A, Mattocks M, Fan T, O'Dowd BF, et al. (2007) Regulation of D1 dopamine receptor trafficking and signaling by caveolin-1. Mol Pharmacol 72: 1157-1170.
34. Vihanto MM, Vindis C, Djonov V, Cerretti DP, Huynh-Do U, (2006) Caveolin-1 is required for signaling and membrane targeting of EphB1 receptor tyrosine kinase. J Cell Sci 119: 2299-2309.
35. Syme CA, Zhang L, Bisello A, (2006) Caveolin-1 regulates cellular trafficking and function of the glucagon-like peptide 1 receptor. Mol Endocrinol 20: 3400-3411.
36. Wang Y, Yamaguchi K, Wada T, Hata K, Zhao XJ, et al. (2002) A close association of the ganglioside-specific sialidase Neu3 with caveolin in membrane microdomains. J Biol Chem 277: 26252-26259.
37. Chun J, Kwon T, Lee EJ, Hyun S, Hong SK, et al. (2005) The subcellular localization of 3-phosphoinositide-dependent protein kinase is controlled by caveolin-1 binding. Biochem Biophys Res Commun 326: 136-146.
38. Hong YH, Kim JY, Lee JH, Chae HG, Jang SS, et al. (2009) Agonist-induced internalization of mGluR1 alpha is mediated by caveolin. J Neurochem 111: 61-71.
39. Xia H, Khalil W, Kahm J, Jessurun J, Kleidon J, et al. (2010) Pathologic caveolin-1 regulation of PTEN in idiopathic pulmonary fibrosis. Am J Pathol 176: 2626-2637.
40. Taira J, Sugishima M, Kida Y, Oda E, Noguchi M, et al. (2011) Caveolin-1 is a competitive inhibitor of heme oxygenase-1 (HO-1) with heme: identification of a minimum sequence in caveolin-1 for binding to HO-1. Biochemistry 50: 6824-6831.
41. Nystrom FH, Chen H, Cong LN, Li YH, Quon MJ, (1999) Caveolin-1 interacts with the insulin receptor and can differentially modulate insulin signaling in transfected Cos-7 cells and rat adipose cells. Mol Endocrinol 13: 2013-2024.
42. Jodoin J, Demeule M, Fenart L, Cecchelli R, Farmer S, et al. (2003) P-glycoprotein in blood-brain barrier endothelial cells: interaction and oligomerization with caveolins. J Neurochem 87: 1010-1023.
43. Sato Y, Sagami I, Shimizu T, (2004) Identification of caveolin-1-interacting sites in neuronal nitric-oxide synthase- Molecular mechanism for inhibition of NO formation. J Biol Chem 279: 8827-8836.
44. Brainard AM, Korovkina VP, England SK, (2009) Disruption of the maxi-K-caveolin-1 interaction alters current expression in human myometrial cells. Reprod Biol Endocrinol 7: 131.
45. Davey NE, Shields DC, Edwards RJ, (2009) Masking residues using context-specific evolutionary conservation significantly improves short linear motif discovery. Bioinformatics 25: 443-450.
46. Dinkel H, Michael S, Weatheritt RJ, Davey NE, Van Roey K, et al. (2012) ELM-the database of eukaryotic linear motifs. Nuc Acids Res 40: D242-251.
47. Fuxreiter M, Tompa P, Simon I, (2007) Local structural disorder imparts plasticity on linear motifs. Bioinformatics 23: 950-956.
48. Dosztanyi Z, Csizmok V, Tompa P, Simon I, (2005) IUPred: web server for the prediction of intrinsically unstructured regions of proteins based on estimated energy content. Bioinformatics 21: 3433-3434.
49. Yamamoto M, Toya Y, Schwencke C, Lisanti MP, Myers MG, (1998) Caveolin is an activator of insulin receptor signaling. J Biol Chem 273: 26962-26968.
50. Boraston AB, Bolam DN, Gilbert HJ, Davies GJ, (2004) Carbohydrate-binding modules: fine-tuning polysaccharide recognition. Biochem J 382: 769-781.
51. Coleman DE, Sprang SR, (1999) Structure of Gialpha1.GppNHp, autoinhibition in a galpha protein-substrate complex. J Biol Chem 274: 16669-16672.
52. Zheng W, Doniach S, (2003) A comparative study of motor-protein motions by using a simple elastic-network model. Proc Natl Acad Sci U.S.A 100: 13253-13258.
53. Chen HL, Zhou HX, (2005) Prediction of solvent accessibility and sites of deleterious mutations from protein sequence. Nucleic Acids Res 33: 3193-3199.
54. Adamczak R, Porollo A, Meller J, (2005) Combining prediction of secondary structure and solvent accessibility in proteins. Proteins Struct Funct Bioinformatics 59: 467-475.
55. Dehouck Y, Kwasigroch JM, Gilis D, Rooman M, (2011) PoPMuSiC 2.1: a web server for the estimation of protein stability changes upon mutation and sequence optimality. Bmc Bioinformatics 12: 151.
56. Dehouck Y, Grosfils A, Folch B, Gilis D, Bogaerts P, et al. (2009) Fast and accurate predictions of protein stability changes upon mutations using statistical potentials and neural networks: PoPMuSiC-2.0. Bioinformatics 25: 2537-2543.
57. Tokuriki N, Stricher F, Schymkowitz J, Serrano L, Tawfik DS, (2007) The stability effects of protein mutations appear to be universally distributed. J Mol Biol 369: 1318-1332.
58. Iwanishi M, Haruta T, Takata Y, Ishibashi O, Sasaoka T, et al. (1993) A mutation (Trp1193->Leu1193) in the tyrosine kinase domain of the insulin-receptor associated with type-A syndrome of insulin resistance. Diabetologia 36: 414-422.
59. Imamura T, Takata Y, Sasaoka T, Takada Y, Morioka H, et al. (1994) Two naturally occurring mutations in the kinase domain of insulin receptor accelerate degradation of the insulin receptor and impair the kinase activity. J Biol Chem 269: 31019-31027.
60. Imamura T, Haruta T, Takata Y, Usui I, Iwata M, et al. (1998) Involvement of heat shock protein 90 in the degradation of mutant insulin receptors by the proteasome. J Biol Chem 273: 11183-11188.
61. Wyse BD, Prior IA, Qian HW, Morrow IC, Nixon S, et al. (2003) Caveolin interacts with the angiotensin II type 1 receptor during exocytic transport but not at the plasma membrane. J Biol Chem 278: 23738-23746.
62. Sotgia F, Razani B, Bonuccelli G, Schubert W, Battista M, et al. (2002) Intracellular retention of glycosylphosphatidyl inositol-linked proteins in caveolin-deficient cells. Mol Cell Biol 22: 3905-3926.
63. Yue L, Mazzone T, (2011) Endogenous adipocyte apolipoprotein E is colocalized with caveolin at the adipocyte plasma membrane. J Lipid Res 52: 489-498.
64. Levin AM, Coroneus JG, Cocco MJ, Weiss GA, (2006) Exploring the interaction between the protein kinase A catalytic subunit and caveolin-1 scaffolding domain with shotgun scanning, oligomer complementation, NMR, and docking. Protein Sci 15: 478-486.
65. Prieto C, Rivas JDL, (2006) APID: Agile Protein Interaction Data Analyzer. Nucleic Acids Res 34: W298-W302.
66. Stark C, Breitkreutz BJ, Chatr-aryamontri A, Boucher L, Oughtred R, et al. (2010) The BioGRID interaction database: 2011 update. Nucleic Acids Res 39: D698-D704.
67. Kerrien S, Aranda B, Breuza L, Bridge A, Broackes-Carter F, et al. (2012) The IntAct molecular interaction database in 2012. Nucleic Acids Res 40: D841-6.
68. Gattiker A, Gasteiger E, Bairoch A, (2002) ScanProsite: a reference implementation of a PROSITE scanning tool. Appl Bioinformatics 1: 107-108.
69. UniProt Consortium, (2012) Reorganizing the protein space at the Universal Protein Resource (UniProt). Nucleic Acids Res 40: D71-5.
70. Kiefer F, Arnold K, Kunzli M, Bordoli L, Schwede T, (2009) The SWISS-MODEL Repository and associated resources. Nucleic Acids Res 37: D387-D392.
71. Kabsch W, Sander C, (1983) Dictionary of protein secondary structure - Pattern-recognition of hydrogen-bonded and geometrical features. Biopolymers 22: 2577-2637.
72. Shatsky M, Nussinov R, Wolfson HJ, (2004) A method for simultaneous alignment of multiple protein structures. Proteins 56: 143-156.
73. Ikezu T, Trapp BD, Song KS, Schlegel A, Lisanti MP, et al. (1998) Caveolae, plasma membrane microdomains for alpha-secretase-mediated processing of the amyloid precursor protein. J Biol Chem 273: 10485-10495.
74. Escriche M, Burgueno J, Ciruela F, Canela EI, Mallol J, et al. (2003) Ligand-induced caveolae-mediated internalization of A1 adenosine receptors: morphological evidence of endosomal sorting and receptor recycling. Exp Cell Res 285: 72-90.
75. Jablonski EM, Hughes FM, (2006) The potential role of caveolin-1 in inhibition of aquaporins during the AVD. Biol Cell 98: 33-42.
76. Carman CV, Lisanti MP, Benovic JL, (1999) Regulation of G protein-coupled receptor kinases by caveolin. J Biol Chem 274: 8858-8864.
77. Vargas L, Nore BF, Berglof A, Heinonen JE, Mattsson PT, et al. (2002) Functional interaction of caveolin-1 with Bruton's tyrosine kinase and Bmx. J Biol Chem 277: 9351-9357.
78. Nilsson R, Ahmad F, Sward K, Andersson U, Weston M, et al. (2006) Plasma membrane cyclic nucleotide phosphodiesterase 3B (PDE3B) is associated with caveolae in primary adipocytes. Cell Signal 18: 1713-1721.
79. Gaudreault SB, Chabot C, Gratton JP, Poirier J, (2004) The caveolin scaffolding domain modifies 2-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor binding properties by inhibiting phospholipase A(2) activity. J Biol Chem 279: 356-362.
80. Couet J, Sargiacomo M, Lisanti MP, (1997) Interaction of a receptor tyrosine kinase, EGF-R, with caveolins- Caveolin binding negatively regulates tyrosine and serine/threonine kinase activities. J Biol Chem 272: 30429-30438.
81. Di Vizio D, Adam RM, Kim J, Kim R, Sotgia F, et al. (2008) Caveolin-1 interacts with a lipid raft-associated population of fatty acid synthase. Cell Cycle 7: 2257-2267.
82. Feng L, Liao WX, Luo Q, Zhang HH, Wang W, et al. (2012) Caveolin-1 orchestrates fibroblast growth factor 2 signaling control of angiogenesis in placental artery endothelial cell caveolae. J Cell Physiol 227: 2480-2491.
83. Adebiyi A, Narayanan D, Jaggar JH, (2011) Caveolin-1 assembles type 1 inositol 1,4,5-trisphosphate receptors and canonical transient receptor potential 3 channels into a functional signaling complex in arterial smooth muscle cells. J Biol Chem 286: 4341-4348.
84. Sundivakkam PC, Kwiatek AM, Sharma TT, Minshall RD, Malik AB, et al. (2009) Caveolin-1 scaffold domain interacts with TRPC1 and IP3R3 to regulate Ca2+ store release-induced Ca2+ entry in endothelial cells. Am J Cell Physiol 293: C403-413.
85. Yamamoto M, Toya Y, Schwencke C, Lisanti MP, Myers MG Jr, et al. (1998) Caveolin is an activator of insulin receptor signaling. J Biol Chem. 273: 26962-26968.
86. Lee KW, Liu BR, Ma LQ, Li HJ, Bang P, et al. (2004) Cellular internalization of insulin-like growth factor binding protein-3- Distinct endocytic pathways facilitate re-uptake and nuclear localization. J Biol Chem 279: 469-476.
87. Sasaki N, Shinomi M, Hirano K, Ui-Tei K, Nishihara S, (2011) LacdiNAc (GalNAcbeta1-4GlcNAc) contributes to self-renewal of mouse embryonic stem cells by regulating leukemia inhibitory factor/STAT3 signaling. Stem Cells 29: 641-650.
88. Martinez-Marmol R, Villalonga N, Sole L, Vicente R, Tamkun MM, et al. (2008) Multiple Kv1.5 targeting to membrane surface microdomains. J Cell Physiol 217: 667-673.
89. de Marco MD, Kremer L, Albar JP, Martinez-Menarguez JA, Ballesta J, et al. (2001) BENE, a novel raft-associated protein of the MAL proteolipid family, interacts with caveolin-1 in human endothelial-like ECV304 cells. J Biol Chem 276: 23009-23017.
90. Chambaut-Guerin AM, Pairault J, (2005) Tumour necrosis factor alpha-induced adipose-related protein (TIARP): co-localization with caveolin-1. Biol Cell 97: 339-347.
91. Boyanapalli M, Lahoud OB, Messiaen L, Kim B, de Sylor MSA, et al. (2006) Neurofibromin binds to caveolin-1 and regulates ras, FAK, and Akt. Biochem Biophys Res Commun 340: 1200-1208.
92. Felley-Bosco E, Bender FC, Courjault-Gautier F, Bron C, Quest AFG, (2000) Caveolin-1 down-regulates inducible nitric oxide synthase via the proteasome pathway in human colon carcinoma cells. Proc Natl Acad Sci USA. 97: 14334-14339.
93. GarciaCardena G, Martasek P, Masters BSS, Skidd PM, Couet J, et al. (1997) Dissecting the interaction between nitric oxide synthase (NOS) and caveolin- Functional significance of the NOS caveolin binding domain in vivo. J Biol Chem 272: 25437-25440.
94. Yamamoto M, Toya Y, Jensen RA, Ishikawa Y, (1999) Caveolin is an inhibitor of platelet-derived growth factor receptor signaling. Exp Cell Res 247: 380-388.
95. Li LK, Ren CH, Tahir SA, Ren CZ, Thompson TC, (2003) Caveolin-1 maintains activated Akt in prostate cancer cells through scaffolding domain binding site interactions with and inhibition of serine/threonine protein phosphatases PP1 and PP2A. Mol Cell Biol 23: 9389-9404.
96. Oka N, Yamamoto M, Schwencke C, Kawabe J, Ebina T, et al. (1997) Caveolin interaction with protein kinase C- Isoenzyme-dependent regulation of kinase activity by the caveolin scaffolding domain peptide. J Biol Chem 272: 33416-33421.
97. Lin D, Zhou J, Zelenka PS, Takemoto DJ, (2003) Protein kinase Cγ regulation of gap junction activity through caveolin-1-containing lipid rafts. Invest Ophthalmol Vis Sci 44: 5259-5268.
98. Karpen HE, Bukowski JT, Hughes T, Gratton JP, Sessa WC, et al. (2001) The sonic hedgehog receptor patched associates with caveolin-1 in cholesterol-rich microdomains of the plasma membrane. J Biol Chem 276: 19503-19511.
99. Caselli A, Mazzinghi B, Camici G, Manao G, Ramponi G, (2002) Some protein tyrosine phosphatases target in part to lipid rafts and interact with caveolin-1. Biochem Biophys Res Commun 296: 692-697.
100. Miyagawa Y, Ohguro H, Odagiri H, Maruyama I, Maeda T, et al. (2003) Aberrantly expressed recoverin is functionally associated with G-protein-coupled receptor kinases in cancer cell lines. Biochem Biophys Res Commun 300: 669-673.
101. Rashid-Doubell F, Tannetta D, Redman CW, Sargent IL, Boyd CA, et al. (2007) Caveolin-1 and lipid rafts in confluent BeWo trophoblasts: evidence for Rock-1 association with caveolin-1. Placenta 28: 139-151.
102. Lin M, DiVito MM, Merajver SD, Boyanapalli M, van Golen KL, (2005) Regulation of pancreatic cancer cell migration and invasion by RhoC GTPase and caveolin-1. Mol Cancer 4: 21.
103. Cha SH, Shin SY, Jung SY, Kim YT, Park YJ, et al. (2004) Evidence for Na+/Ca2+ exchanger 1 association with caveolin-1 and-2 in C6 glioma cells. IUBMB Life 56: 621-627.
104. Cai T, Wang H, Chen Y, Liu L, Gunning WT, et al. (2008) Regulation of caveolin-1 membrane trafficking by the Na/K-ATPase. J Cell Biol 182: 1153-1169.
105. Wang H, Haas M, Liang M, Cai T, Tian J, et al. (2004) Ouabain assembles signaling cascades through the caveolar Na+/K+-ATPase. J Biol Chem 279: 17250-17259.
106. Lee WK, Choi JK, Cha SH, (2008) Co-localization and interaction of human organic anion transporter 4 with caveolin-1 in primary cultured human placental trophoblasts. Exp Mol Med 40: 505-513.
107. Kwak JO, Kim HW, Song JH, Kim MJ, Park HS, et al. (2005) Evidence for rat organic anion transporter 3 association with caveolin-1 in rat kidney. IUBMB Life 57: 109-117.
108. Gaillard S, Bartoli M, Castets F, Monneron A, (2001) Striatin, a calmodulin-dependent scaffolding protein, directly binds caveolin-1. FEBS Lett 508: 49-52.
109. Davies LM, Purves GI, Barrett-Jolley R, Dart C, (2010) Interaction with caveolin-1 modulates vascular ATP-sensitive potassium (KATP) channel activity. J Physiol 588: 3254-3265.
110. Wang XM, Kim HP, Nakahira K, Ryter SW, Choi AM, (2009) The Heme Oxygenase-1/Carbon Monoxide Pathway Suppresses TLR4 Signaling by Regulating the Interaction of TLR4 with Caveolin-1. J Immunol 182: 3809-3818.
111. Feng X, Gaeta ML, Madge LA, Yang JH, Bradley JR, et al. (2001) Caveolin-1 associates with TRAF2 to form a complex that is recruited to tumor necrosis factor receptors. J Biol Chem 276: 8341-8349.
112. Kwiatek AM, Minshall RD, Cool DR, Skidgel RA, Malik AB, et al. (2006) Caveolin-1 regulates store-operated Ca2+ influx by binding of its scaffolding domain to transient receptor potential channel-1 in endothelial cells. Mol Pharmacol 70: 1174-1183.
113. LeClerc PC, Auger-Messier M, Lanctot PM, Escher E, Leduc R, et al. (2002) A polyaromatic caveolin-binding-like motif in the cytoplasmic tail of the type 1 receptor for angiotensin II plays an important role in receptor trafficking and signaling. Endocrinology 143: 4702-4710.
114. Labrecque L, Royal I, Surprenant DS, Patterson C, Gingras D, et al. (2003) Regulation of vascular endothelial growth factor receptor-2 activity by caveolin-1 and plasma membrane cholesterol. Mol Biol Cell 14: 334-347.
115. Galvagni F, Anselmi F, Salameh A, Orlandini M, Rocchigiani M, et al. (2007) Vascular endothelial growth factor receptor-3 activity is modulated by its association with caveolin-1 on endothelial membrane. Biochemistry 46: 3998-4005.
116. Lu ML, Schneider MC, Zheng YX, Zhang XB, Richie JP, (2001) Caveolin-1 interacts with androgen receptor- A positive modulator of androgen receptor mediated transactivation. J Biol Chem 276: 13442-13451.
117. Storch CH, Ehehalt R, Haefeli WE, Weiss J, (2007) Localization of the human breast cancer resistance protein (BCRP/ABCG2) in lipid rafts/caveolae and modulation of its activity by cholesterol in vitro. J Pharmacol Exp Ther 323: 257-264.
118. Yu F, Sun L, Machaca K, (2010) Constitutive recycling of the store-operated Ca2+ channel Orai1 and its internalization during meiosis. J Cell Biol 191: 523-535.
119. Brennan D, Peltonen S, Dowling A, Medhat W, Green KJ, et al. (2011) A role for caveolin-1 in desmoglein binding and desmosome dynamics. Oncogene 10.1038/onc.2011.346.
120. Schlegel A, Wang CG, Pestell RG, Lisanti MP, (2001) Ligand-independent activation of oestrogen receptor alpha by caveolin-1. Biochem J 359: 203-210.
121. Mayer G, Boileau G, Bendayan M, (2004) The proprotein convertase furin colocalizes with caveolin-1 in the Golgi apparatus and endosomes of hepatocytes. Cell Tissue Res 316: 55-63.
122. Langlois S, Cowan KN, Shao Q, Cowan BJ, Laird DW, (2008) Caveolin-1 and-2 interact with connexin43 and regulate gap junctional intercellular communication in keratinocytes. Mol Biol Cell. 19: 912-928.
123. Yamaguchi Y, Yasuoka H, Stolz DB, Feghali-Bostwick CA, (2011) Decreased caveolin-1 levels contribute to fibrosis and deposition of extracellular IGFBP-5. J Cell Mol Med 15: 957-969.
124. Burgermeister E, Tencer L, Liscovitch M, (2003) Peroxisome proliferator-activated receptor-gamma upregulates caveolin-1 and caveolin-2 expression in human carcinoma cells. Oncogene 22: 3888-3900.
125. Burgermeister E, Friedrich T, Hitkova I, Regel I, Einwachter H, et al. (2011) The Ras inhibitors caveolin-1 and docking protein 1 activate peroxisome proliferator-activated receptor gamma through spatial relocalization at helix 7 of its ligand-binding domain. Mol Cell Biol 31: 3497-3510.
126. Spisni E, Griffoni C, Santi S, Riccio M, Marulli R, et al. (2001) Colocalization prostacyclin (PGI2) synthase-caveolin-1 in endothelial cells and new roles for PGI2 in angiogenesis. Exp Cell Res 266: 31-43.
127. Steinberg SF, (2008) Structural basis of protein kinase C isoform function. Physiol Rev 88: 1341-1378.
128. Razani B, Zhang XL, Bitzer M, von Gersdorff G, Bottinger EP, et al. (2001) Caveolin-1 regulates transforming growth factor (TGF)-beta/SMAD signaling through an interaction with the TGF-beta type I receptor. J Biol Chem 276: 6727-6738.
129. Zhang M, Lee SJ, An C, Xu JF, Joshi B, et al. (2011) Caveolin-1 mediates Fas-BID signaling in hyperoxia-induced apoptosis. Free Radic Biol Med 50: 1252-1262.
130. Ramirez CM, Gonzalez M, Diaz M, Alonso R, Ferrer I, et al. (2009) VDAC and ERalpha interaction in caveolae from human cortex is altered in Alzheimer's disease. Mol Cell Neurosci 42: 172-183.
131. Yun CH, Boggon TJ, Li Y, Woo MS, Greulich H, et al. (2007) Structures of lung cancer-derived EGFR mutants and inhibitor complexes: mechanism of activation and insights into differential inhibitor sensitivity. Cancer Cell 11: 217-227.
132. Wu J, Tseng YD, Xu CF, Neubert TA, White MF, et al. (2008) Structural and biochemical characterization of the KRLB region in insulin receptor substrate-2. Nat Struct Mol Biol 15: 251-258.
133. Lee JO, Yang H, Georgescu MM, Di Cristofano A, Maehama T, et al. (1999) Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association. Cell 99: 323-334.
134. Yuan P, Leonetti MD, Pico AR, Hsiung Y, MacKinnon R, (2010) Structure of the human BK channel Ca2+-activation apparatus at 3.0 A resolution. Science 329: 182-186.
135. Komander D, Kular GS, Schuttelkopf AW, Deak M, Prakash KR, et al. (2004) Interactions of LY333531 and other bisindolyl maleimide inhibitors with PDK1. Structure 12: 215-226.