Down-regulation of the cavin family proteins in breast cancer

Journal of Cellular Biochemistry

Volumn 113, Issue 1, 2012, Pages 322-328

  Bai, Lin ^a   Deng, Xiaoli ^a   Li, Qian ^a   Wang, Miao ^a   An, Wei ^a   Deli, A ^a   Gao, Zhuo ^b   Xie, Yuntao ^c   Dai, Yifan ^b   Cong, Yu Sheng ^a  

^a Beijing Normal University   (China)

^b NANJING MEDICAL UNIVERSITY   (China)

^c PEKING UNIVERSITY CANCER HOSPITAL AND INSTITUTE   (China)

Author keywords

Caveolae; Caveolin 1; Methylation; PTRF; SDPR; SRBC

Indexed keywords

CAVEOLIN 1; DNA; GENE PRODUCT; POLYMERASE 1 AND TRANSCRIPT RELEASE FACTOR; PROTEIN; SERUM DEPRIVATION RESPONSE FACTOR RELATED GENE PRODUCT THAT BINDS TO C KINASE; SERUM DEPRIVATION RESPONSE PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CANCER TISSUE; CAVEOLA; CLINICAL ARTICLE; CONTROLLED STUDY; DNA METHYLATION; DOWN REGULATION; EPIGENETICS; GENE INACTIVATION; HUMAN; HUMAN CELL; HUMAN TISSUE; INTRACELLULAR SIGNALING; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION;

BASE SEQUENCE; BREAST; BREAST NEOPLASMS; CARRIER PROTEINS; CAVEOLAE; CAVEOLIN 1; CELL LINE, TUMOR; CELL MEMBRANE; DNA METHYLATION; DOWN-REGULATION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; PROMOTER REGIONS, GENETIC; RNA-BINDING PROTEINS; SEQUENCE ANALYSIS, DNA; SIGNAL TRANSDUCTION;

EID: 84055177023     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.23358     Document Type: Article

References (24)

1. Bai L, Deng X, Li J, Wang M, Li Q, An W, A D, Cong YS,. 2011. Regulation of cellular senescence by the essential caveolar component PTRF/cavin-1. Cell Res 21: 1088-1101.
2. Bastiani M, Parton RG,. 2010. Caveolae at a glance. J Cell Sci 123: 3831-3836.
3. Chan TF, Su TH, Yeh KT, Chang JY, Lin TH, Chen JC, Yuang SS, Chang JG,. 2003. Mutational, epigenetic and expressional analyses of caveolin-1 gene in cervical cancers. Int J Oncol 23: 599-604.
4. Chen ST, Lin SY, Yeh KT, Kuo SJ, Chan WL, Chu YP, Chang JG,. 2004. Mutational, epigenetic and expressional analyses of caveolin-1 gene in breast cancers. Int J Mol Med 14: 577-582.
5. Fiucci G, Ravid D, Reich R, Liscovitch M,. 2002. Caveolin-1 inhibits anchorage-independent growth, anoikis and invasiveness in MCF-7 human breast cancer cells. Oncogene 21: 2365-2375. (Pubitemid 34413560)
6. Hansen CG, Nichols BJ,. 2010. Exploring the caves: Cavins, caveolins and caveolae. Trends Cell Biol 20: 177-186.
7. Hayashi YK, Matsuda C, Ogawa M, Goto K, Tominaga K, Mitsuhashi S, Park YE, Nonaka I, Hino-Fukuyo N, Haginoya K, Sugano H, Nishino I,. 2009. Human PTRF mutations cause secondary deficiency of caveolins resulting in muscular dystrophy with generalized lipodystrophy. J Clin Invest 119: 2623-2633.
8. Hill MM, Bastiani M, Luetterforst R, Kirkham M, Kirkham A, Nixon SJ, Walser P, Abankwa D, Oorschot VM, Martin S, Hancock JF, Parton RG,. 2008. PTRF-Cavin, a conserved cytoplasmic protein required for caveola formation and function. Cell 132: 113-124.
9. Jones PA, Baylin SB,. 2007. The epigenomics of cancer. Cell 128: 683-692. (Pubitemid 46273572)
10. Lee JH, Byun DS, Lee MG, Ryu BK, Kang MJ, Chae KS, Lee KY, Kim HJ, Park H, Chi SG,. 2008. Frequent epigenetic inactivation of hSRBC in gastric cancer and its implication in attenuated p53 response to stresses. Int J Cancer 122: 1573-1584. (Pubitemid 351294966)
11. Li X, Jia Z, Shen Y, Ichikawa H, Jarvik J, Nagele RG, Goldberg GS,. 2008. Coordinate suppression of Sdpr and Fhl1 expression in tumors of the breast, kidney, and prostate. Cancer Sci 99: 1326-1333. (Pubitemid 351761720)
12. Liu L, Pilch PF,. 2008. A critical role of cavin (polymerase I and transcript release factor) in caveolae formation and organization. J Biol Chem 283: 4314-4322.
13. Liu P, Rudick M, Anderson RG,. 2002. Multiple functions of caveolin-1. J Biol Chem 277: 41295-41298. (Pubitemid 35257426)
14. Liu L, Brown D, McKee M, Lebrasseur NK, Yang D, Albrecht KH, Ravid K, Pilch PF,. 2008. Deletion of Cavin/PTRF causes global loss of caveolae, dyslipidemia, and glucose intolerance. Cell Metab 8: 310-317.
15. Nabi IR,. 2009. Cavin fever: Regulating caveolae. Nat Cell Biol 11: 789-791.
16. Parton RG, Simons K,. 2007. The multiple faces of caveolae. Nat Rev Mol Cell Biol 8: 185-194.
17. Rajab A, Straub V, McCann LJ, Seelow D, Varon R, Barresi R, Schulze A, Lucke B, Lutzkendorf S, Karbasiyan M, Bachmann S, Spuler S, Schuelke M,. 2010. Fatal cardiac arrhythmia and long-QT syndrome in a new form of congenital generalized lipodystrophy with muscle rippling (CGL4) due to PTRF-CAVIN mutations. PLoS Genet 6: e1000874.
18. Sotgia F, Rui H, Bonuccelli G, Mercier I, Pestell RG, Lisanti MP,. 2006. Caveolin-1, mammary stem cells, and estrogen-dependent breast cancers. Cancer Res 66: 10647-10651. (Pubitemid 44876957)
19. Tong SY, Ki KD, Lee JM, Kang MJ, Ha TK, Chung SI, Chi SG, Lee SK,. 2010. Frequent inactivation of hSRBC in ovarian cancers by promoter CpG island hypermethylation. Acta Obstet Gynecol Scand 89: 629-635.
20. Williams TM, Lisanti MP,. 2005. Caveolin-1 in oncogenic transformation, cancer, and metastasis. Am J Physiol Cell Physiol 288: C494-506. (Pubitemid 40229478)
21. Williams TM, Cheung MW, Park DS, Razani B, Cohen AW, Muller WJ, Di Vizio D, Chopra NG, Pestell RG, Lisanti MP,. 2003. Loss of caveolin-1 gene expression accelerates the development of dysplastic mammary lesions in tumor-prone transgenic mice. Mol Biol Cell 14: 1027-1042. (Pubitemid 36337450)
22. Williams TM, Lee H, Cheung MW, Cohen AW, Razani B, Iyengar P, Scherer PE, Pestell RG, Lisanti MP,. 2004. Combined loss of INK4a and caveolin-1 synergistically enhances cell proliferation and oncogene-induced tumorigenesis: Role of INK4a/CAV-1 in mammary epithelial cell hyperplasia. J Biol Chem 279: 24745-24756. (Pubitemid 38725342)
23. Xu XL, Wu LC, Du F, Davis A, Peyton M, Tomizawa Y, Maitra A, Tomlinson G, Gazdar AF, Weissman BE, Bowcock AM, Baer R, Minna JD,. 2001. Inactivation of human SRBC, located within the 11p15.5-p15.4 tumor suppressor region, in breast and lung cancers. Cancer Res 61: 7943-7949. (Pubitemid 33049385)
24. Zochbauer-Muller S, Fong KM, Geradts J, Xu X, Seidl S, End-Pfutzenreuter A, Lang G, Heller G, Zielinski CC, Gazdar AF, Minna JD,. 2005. Expression of the candidate tumor suppressor gene hSRBC is frequently lost in primary lung cancers with and without DNA methylation. Oncogene 24: 6249-6255. (Pubitemid 43080048)